التداخل بين هيدروكورتيزون وميتوكسانترون

Among 112 patients evaluable for safety on the mitoxantrone injection + hydrocortisone arm of the CALGB trial, 18 patients (19%) had a reduction in cardiac function, 5 patients (5%) had cardiac ischemia, and 2 patients (2%) experienced pulmonary edema.

Following concurrent administration of mitoxantrone injection with corticosteroids, no evidence of drug interactions has been observed.