التداخل بين ميتوكسانترون وبريدنيزون

In a randomized comparative trial of mitoxantrone injection plus low-dose prednisone vs. low-dose prednisone, 7 of 128 patients (5.5 %) treated with mitoxantrone injection had a cardiac event defined as any decrease in LVEF below the normal range, congestive heart failure (n = 3), or myocardial ischemia.

Following concurrent administration of mitoxantrone injection with corticosteroids, no evidence of drug interactions has been observed.