التداخل بين إيماتينيب وميثوتريكسات

Gleevec may delay the clearance of methotrexate when methotrexate is used at high doses (> 500 mg/m 2 ).

Interactions With Methotrexate Gleevec may delay the clearance of methotrexate and result in sustained methotrexate concentrations when methotrexate is used at high doses (> 500 mg/m 2 ).

Refer to the prescribing information for methotrexate injection for recommendations on management of methotrexate concentrations.