التداخل بين نيفيديبين وأوميبرازول

Antisecretory Drugs Omeprazole: In healthy volunteers receiving a single dose of 10 mg nifedipine, AUC and C max of nifedipine after pre-treatment with omeprazole 20 mg q.d. for 8 days were 1.26 and 0.87 times those after pre-treatment with placebo.

Pre-treatment with or co-administration of omeprazole did not impact the effect of nifedipine on blood pressure or heart rate.

The impact of omeprazole on nifedipine is not likely to be of clinical relevance.