التداخل بين أوميبرازول وبيكربونات الصوديوم وريفامبيسين

John’s Wort or Rifampin : Avoid concomitant use of KONVOMEP.

John’s Wort, rifampin : Avoid concomitant use with KONVOMEP [see Warnings and Precautions ( 5.11 )] .

John’s wort or rifampin) can substantially decrease omeprazole concentrations [see Drug Interactions ( 7 )] .

Table 6: Clinically Relevant Interactions Affecting Omeprazole when Co-Administered with Other Drugs CYP2C19 or CYP3A4 Inducers Clinical Impact: Decreased exposure of omeprazole when used concomitantly with strong inducers [see Clinical Pharmacology ( 12.3 )] .

John’s wort or rifampin.

Quinine Prevention or Management : Avoid concomitant use Decrease AUC by 75%-85% Telithromycin Decrease AUC by 86% Theophylline Decrease exposure by 20%-40% Effect of Other Drugs on Rifampin Concomitant antacid administration may reduce the absorption of rifampin.

Daily doses of rifampin should be given at least 1 hour before the ingestion of antacids.