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Wechselwirkungen von Hyaluronidase

Hyaluronidase (Hylenex, Amphadase, Vitrase) hat in den von uns erfassten FDA-Fachinformationen und Faktenblättern 106 dokumentierte Wechselwirkungen: 12 schwerwiegende, 78 mittelschwere, 16 geringfügige und 0, bei denen eine Fachinformation keine relevante Wechselwirkung berichtet. Jeder Eintrag unten zitiert den Satz, auf dem er beruht. Diese Medikamentenseite ist ein Ausgangspunkt, kein Urteil über Ihre persönliche Situation.

Wechselwirkungen laut Fachinformation

Schwerwiegende Wechselwirkungen (12)

  • AdrenalinSympathomimetikumSchwerwiegend

    • Hyaluronidase should not be used to enhance the absorption and dispersion of dopamine and/or alpha agonist drugs ( 7.2 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • ApraclonidinAlpha-Adrenozeptor-AgonistSchwerwiegend

    • Hyaluronidase should not be used to enhance the absorption and dispersion of dopamine and/or alpha agonist drugs ( 7.2 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • BrimonidinAlpha-Adrenozeptor-AgonistSchwerwiegend

    • Hyaluronidase should not be used to enhance the absorption and dispersion of dopamine and/or alpha agonist drugs ( 7.2 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Brimonidin und TimololAlpha-Adrenozeptor-AgonistSchwerwiegend

    • Hyaluronidase should not be used to enhance the absorption and dispersion of dopamine and/or alpha agonist drugs ( 7.2 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • ClonidinAlpha-Adrenozeptor-AgonistSchwerwiegend

    • Hyaluronidase should not be used to enhance the absorption and dispersion of dopamine and/or alpha agonist drugs ( 7.2 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • DexmedetomidinAlpha-Adrenozeptor-AgonistSchwerwiegend

    • Hyaluronidase should not be used to enhance the absorption and dispersion of dopamine and/or alpha agonist drugs ( 7.2 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • GuanfacinAlpha-Adrenozeptor-AgonistSchwerwiegend

    • Hyaluronidase should not be used to enhance the absorption and dispersion of dopamine and/or alpha agonist drugs ( 7.2 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • LofexidinAlpha-Adrenozeptor-AgonistSchwerwiegend

    • Hyaluronidase should not be used to enhance the absorption and dispersion of dopamine and/or alpha agonist drugs ( 7.2 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • MethyldopaAntihypertensivumSchwerwiegend

    • Hyaluronidase should not be used to enhance the absorption and dispersion of dopamine and/or alpha agonist drugs ( 7.2 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • MidodrinAlpha-Adrenozeptor-AgonistSchwerwiegend

    • Hyaluronidase should not be used to enhance the absorption and dispersion of dopamine and/or alpha agonist drugs ( 7.2 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • TizanidinMuskelrelaxansSchwerwiegend

    • Hyaluronidase should not be used to enhance the absorption and dispersion of dopamine and/or alpha agonist drugs ( 7.2 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • VincristinSchwerwiegend

    Local injection of hyaluronidase and the application of moderate heat to the area of leakage help disperse the drug and are thought to minimize discomfort and the possibility of cellulitis. (Fachinformation zu Vincristin, Boxed Warning (umrahmter Warnhinweis))

Mittelschwere Wechselwirkungen (78)

  • AcetylsalicylsäureNSARMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Acetylsalicylsäure und DipyridamolThrombozytenaggregationshemmerMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Articain und AdrenalinLokalanästhetikumMittelschwer

    Admixture stability studies have shown that 2% lidocaine with 1:100,000 or 1:200,000 epinephrine is incompatible with hyaluronidase due to the presence of sodium metabisulfite, a common additive in anesthetic products containing epinephrine. (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • AzelastinAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Azelastin und FluticasonAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • BalsalazidSalicylatMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • BismutsubsalicylatSalicylatMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Brompheniramin, Pseudoephedrin und DextromethorphanAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • BupivacainLokalanästhetikumMittelschwer

    • Local anesthetics: Hyaluronidase hastens onset and shortens duration of effect, increases incidence of systemic reactions ( 7.3 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Bupivacain und AdrenalinLokalanästhetikumMittelschwer

    Admixture stability studies have shown that 2% lidocaine with 1:100,000 or 1:200,000 epinephrine is incompatible with hyaluronidase due to the presence of sodium metabisulfite, a common additive in anesthetic products containing epinephrine. (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Butalbital, Acetylsalicylsäure und KoffeinBarbituratMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Butalbital, Acetylsalicylsäure, Koffein und CodeinBarbituratMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • CarbinoxaminAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • CetirizinAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • ChloroprocainLokalanästhetikumMittelschwer

    • Local anesthetics: Hyaluronidase hastens onset and shortens duration of effect, increases incidence of systemic reactions ( 7.3 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • ChlorphenaminAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • ClemastinAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • CyproheptadinAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • DesfluranAllgemeinanästhetikumMittelschwer

    • Local anesthetics: Hyaluronidase hastens onset and shortens duration of effect, increases incidence of systemic reactions ( 7.3 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • DesloratadinAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Desogestrel und Ethinylestradiolorales KontrazeptivumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • DexchlorpheniraminAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • DiflunisalNSARMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • DimenhydrinatAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • DiphenhydraminAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • DoxylaminAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Doxylamin und PyridoxinAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Drospirenon und Ethinylestradiolorales KontrazeptivumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • EstradiolEstrogenMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Estradiol und Dienogestorales KontrazeptivumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Estradiol und NorethisteronEstrogenMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • EtomidatAllgemeinanästhetikumMittelschwer

    • Local anesthetics: Hyaluronidase hastens onset and shortens duration of effect, increases incidence of systemic reactions ( 7.3 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Etonogestrel und EthinylestradiolEstrogenMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Etynodioldiacetat und Ethinylestradiolorales KontrazeptivumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • FexofenadinAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • FulvestrantEstrogenMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Hydrocodon und ChlorphenaminOpioidMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • HydroxyzinAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • IsofluranAllgemeinanästhetikumMittelschwer

    • Local anesthetics: Hyaluronidase hastens onset and shortens duration of effect, increases incidence of systemic reactions ( 7.3 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • KetaminZNS-dämpfendes ArzneimittelMittelschwer

    • Local anesthetics: Hyaluronidase hastens onset and shortens duration of effect, increases incidence of systemic reactions ( 7.3 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • KokainLokalanästhetikumMittelschwer

    • Local anesthetics: Hyaluronidase hastens onset and shortens duration of effect, increases incidence of systemic reactions ( 7.3 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Konjugierte EstrogeneEstrogenMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Konjugierte Estrogene und BazedoxifenEstrogenMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • LevocetirizinAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Levonorgestrel und Ethinylestradiolorales KontrazeptivumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • LevothyroxinSchilddrüsenhormonMittelschwer

    …recommended that appropriate references first be consulted to determine the usual precautions for the use of the other drug; e.g., when epinephrine is injected along with hyaluronidase, the precautions for the use of epinephrine in cardiovascular disease, thyroid disease, diabetes, digital nerve block, ischemia of the fingers and toes etc., should be observed. (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Levothyroxin und LiothyroninSchilddrüsenhormonMittelschwer

    …recommended that appropriate references first be consulted to determine the usual precautions for the use of the other drug; e.g., when epinephrine is injected along with hyaluronidase, the precautions for the use of epinephrine in cardiovascular disease, thyroid disease, diabetes, digital nerve block, ischemia of the fingers and toes etc., should be observed. (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • LidocainLokalanästhetikumMittelschwer

    Admixture stability studies have shown that 2% lidocaine with 1:100,000 or 1:200,000 epinephrine is incompatible with hyaluronidase due to the presence of sodium metabisulfite, a common additive in anesthetic products containing epinephrine. (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Lidocain und AdrenalinLokalanästhetikumMittelschwer

    Admixture stability studies have shown that 2% lidocaine with 1:100,000 or 1:200,000 epinephrine is incompatible with hyaluronidase due to the presence of sodium metabisulfite, a common additive in anesthetic products containing epinephrine. (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Lidocain und PrilocainLokalanästhetikumMittelschwer

    Admixture stability studies have shown that 2% lidocaine with 1:100,000 or 1:200,000 epinephrine is incompatible with hyaluronidase due to the presence of sodium metabisulfite, a common additive in anesthetic products containing epinephrine. (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • LiothyroninSchilddrüsenhormonMittelschwer

    …recommended that appropriate references first be consulted to determine the usual precautions for the use of the other drug; e.g., when epinephrine is injected along with hyaluronidase, the precautions for the use of epinephrine in cardiovascular disease, thyroid disease, diabetes, digital nerve block, ischemia of the fingers and toes etc., should be observed. (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • LoratadinAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • MeclozinAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Menthol und MethylsalicylatSalicylatMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • MepivacainLokalanästhetikumMittelschwer

    • Local anesthetics: Hyaluronidase hastens onset and shortens duration of effect, increases incidence of systemic reactions ( 7.3 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • MesalazinSalicylatMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • MethohexitalBarbituratMittelschwer

    • Local anesthetics: Hyaluronidase hastens onset and shortens duration of effect, increases incidence of systemic reactions ( 7.3 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • NatriumhydrogencarbonatAntazidumMittelschwer

    Extravasation: Prompt elevation of the area, warmth, and local injection of lidocaine or hyaluronidase are recommended to reduce the likelihood of tissue sloughing at the site. (Fachinformation zu Natriumhydrogencarbonat, Warnhinweise und Vorsichtsmaßnahmen)

  • Norelgestromin und EthinylestradiolEstrogenMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Norethisteron und Ethinylestradiolorales KontrazeptivumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Norgestimat und Ethinylestradiolorales KontrazeptivumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Norgestrel und Ethinylestradiolorales KontrazeptivumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • OlopatadinAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Olopatadin und MometasonAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Orphenadrin, Acetylsalicylsäure und KoffeinMuskelrelaxansMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Prilocain und AdrenalinLokalanästhetikumMittelschwer

    Admixture stability studies have shown that 2% lidocaine with 1:100,000 or 1:200,000 epinephrine is incompatible with hyaluronidase due to the presence of sodium metabisulfite, a common additive in anesthetic products containing epinephrine. (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • PromethazinAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Promethazin und CodeinOpioidMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Promethazin und DextromethorphanAntihistaminikumMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • PropofolZNS-dämpfendes ArzneimittelMittelschwer

    • Local anesthetics: Hyaluronidase hastens onset and shortens duration of effect, increases incidence of systemic reactions ( 7.3 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • PropylthiouracilThyreostatikumMittelschwer

    …recommended that appropriate references first be consulted to determine the usual precautions for the use of the other drug; e.g., when epinephrine is injected along with hyaluronidase, the precautions for the use of epinephrine in cardiovascular disease, thyroid disease, diabetes, digital nerve block, ischemia of the fingers and toes etc., should be observed. (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • RopivacainLokalanästhetikumMittelschwer

    • Local anesthetics: Hyaluronidase hastens onset and shortens duration of effect, increases incidence of systemic reactions ( 7.3 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • SalsalatNSARMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • SevofluranAllgemeinanästhetikumMittelschwer

    • Local anesthetics: Hyaluronidase hastens onset and shortens duration of effect, increases incidence of systemic reactions ( 7.3 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • SulfasalazinSulfonamidMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • TeriparatidSchilddrüsenhormonMittelschwer

    …recommended that appropriate references first be consulted to determine the usual precautions for the use of the other drug; e.g., when epinephrine is injected along with hyaluronidase, the precautions for the use of epinephrine in cardiovascular disease, thyroid disease, diabetes, digital nerve block, ischemia of the fingers and toes etc., should be observed. (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • ThiamazolThyreostatikumMittelschwer

    …recommended that appropriate references first be consulted to determine the usual precautions for the use of the other drug; e.g., when epinephrine is injected along with hyaluronidase, the precautions for the use of epinephrine in cardiovascular disease, thyroid disease, diabetes, digital nerve block, ischemia of the fingers and toes etc., should be observed. (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Veresterte Estrogene und MethyltestosteronEstrogenMittelschwer

    • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

Geringfügige Erwähnungen (16)

  • AlprazolamBenzodiazepinGeringfügig

    • Furosemide, the benzodiazepines and phenytoin are incompatible with hyaluronidase ( 7.1 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • ChlordiazepoxidBenzodiazepinGeringfügig

    • Furosemide, the benzodiazepines and phenytoin are incompatible with hyaluronidase ( 7.1 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • Chlordiazepoxid und ClidiniumbromidBenzodiazepinGeringfügig

    • Furosemide, the benzodiazepines and phenytoin are incompatible with hyaluronidase ( 7.1 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • ClobazamBenzodiazepinGeringfügig

    • Furosemide, the benzodiazepines and phenytoin are incompatible with hyaluronidase ( 7.1 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • ClonazepamBenzodiazepinGeringfügig

    • Furosemide, the benzodiazepines and phenytoin are incompatible with hyaluronidase ( 7.1 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • DiazepamBenzodiazepinGeringfügig

    • Furosemide, the benzodiazepines and phenytoin are incompatible with hyaluronidase ( 7.1 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • DikaliumclorazepatBenzodiazepinGeringfügig

    • Furosemide, the benzodiazepines and phenytoin are incompatible with hyaluronidase ( 7.1 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • EstazolamBenzodiazepinGeringfügig

    • Furosemide, the benzodiazepines and phenytoin are incompatible with hyaluronidase ( 7.1 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • FlumazenilBenzodiazepinGeringfügig

    • Furosemide, the benzodiazepines and phenytoin are incompatible with hyaluronidase ( 7.1 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • FurosemidSchleifendiuretikumGeringfügig

    • Furosemide, the benzodiazepines and phenytoin are incompatible with hyaluronidase ( 7.1 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • LorazepamBenzodiazepinGeringfügig

    • Furosemide, the benzodiazepines and phenytoin are incompatible with hyaluronidase ( 7.1 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • MidazolamBenzodiazepinGeringfügig

    • Furosemide, the benzodiazepines and phenytoin are incompatible with hyaluronidase ( 7.1 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • OxazepamBenzodiazepinGeringfügig

    • Furosemide, the benzodiazepines and phenytoin are incompatible with hyaluronidase ( 7.1 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • PhenytoinAntiepileptikumGeringfügig

    • Furosemide, the benzodiazepines and phenytoin are incompatible with hyaluronidase ( 7.1 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • TemazepamBenzodiazepinGeringfügig

    • Furosemide, the benzodiazepines and phenytoin are incompatible with hyaluronidase ( 7.1 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

  • TriazolamBenzodiazepinGeringfügig

    • Furosemide, the benzodiazepines and phenytoin are incompatible with hyaluronidase ( 7.1 ) (Fachinformation zu Hyaluronidase, Arzneimittelwechselwirkungen)

Prüfen Sie Hyaluronidase gegen alles, was Sie einnehmen. Fügen Sie Ihre gesamte Liste hinzu; alle Paare werden auf einmal geprüft.

Im Wechselwirkungscheck öffnen

Keine medizinische Beratung. Der Schweregrad gibt die Formulierung der Fachinformation wieder, nicht Ihre persönlichen Umstände. Eine als „schwerwiegend“ eingestufte Wechselwirkung kann unter Aufsicht Routine sein, und eine „geringfügige“ kann bei hohen Dosen von Bedeutung sein. Fragen Sie in einer Apotheke nach.