Wechselwirkungen von Isotretinoin

Isotretinoin (Accutane, Absorica, Claravis), ein Retinoid, hat in den von uns erfassten FDA-Fachinformationen und Faktenblättern 44 dokumentierte Wechselwirkungen: 8 schwerwiegende, 7 mittelschwere, 29 geringfügige und 0, bei denen eine Fachinformation keine relevante Wechselwirkung berichtet. Jeder Eintrag unten zitiert den Satz, auf dem er beruht. Diese Medikamentenseite ist ein Ausgangspunkt, kein Urteil über Ihre persönliche Situation.

Wechselwirkungen laut Fachinformation

Schwerwiegende Wechselwirkungen (8)

  • AcitretinRetinoidSchwerwiegend

    Acitretin is contraindicated in cases of hypersensitivity (e.g., angioedema, urticaria) to the preparation (acitretin or excipients) or to other retinoids . (Fachinformation zu Acitretin, Gegenanzeigen)

  • Intracranial Hypertension ( Pseudotumor Cerebri ): Avoid concomitant use with tetracyclines ( 5.5 ) (Fachinformation zu Isotretinoin, Warnhinweise und Vorsichtsmaßnahmen)

  • DemeclocyclinTetracyclin-AntibiotikumSchwerwiegend

    Intracranial Hypertension ( Pseudotumor Cerebri ): Avoid concomitant use with tetracyclines ( 5.5 ) (Fachinformation zu Isotretinoin, Warnhinweise und Vorsichtsmaßnahmen)

  • DoxycyclinTetracyclin-AntibiotikumSchwerwiegend

    Intracranial Hypertension ( Pseudotumor Cerebri ): Avoid concomitant use with tetracyclines ( 5.5 ) (Fachinformation zu Isotretinoin, Warnhinweise und Vorsichtsmaßnahmen)

  • MinocyclinTetracyclin-AntibiotikumSchwerwiegend

    Intracranial Hypertension ( Pseudotumor Cerebri ): Avoid concomitant use with tetracyclines ( 5.5 ) (Fachinformation zu Isotretinoin, Warnhinweise und Vorsichtsmaßnahmen)

  • TetracyclinTetracyclin-AntibiotikumSchwerwiegend

    Intracranial Hypertension ( Pseudotumor Cerebri ): Avoid concomitant use with tetracyclines ( 5.5 ) (Fachinformation zu Isotretinoin, Warnhinweise und Vorsichtsmaßnahmen)

  • TigecyclinTetracyclin-AntibiotikumSchwerwiegend

    Intracranial Hypertension ( Pseudotumor Cerebri ): Avoid concomitant use with tetracyclines ( 5.5 ) (Fachinformation zu Isotretinoin, Warnhinweise und Vorsichtsmaßnahmen)

  • TretinoinRetinoidSchwerwiegend

    Tretinoin capsules are contraindicated in patients with a known hypersensitivity to tretinoin capsules, any of its components, or other retinoids. (Fachinformation zu Tretinoin, Gegenanzeigen)

Mittelschwere Wechselwirkungen (7)

  • AlkoholAlkoholMittelschwer

    Some patients have been able to reverse triglyceride elevation by reduction in weight and restriction of dietary fat and alcohol while continuing isotretinoin or through dosage reduction. (Fachinformation zu Isotretinoin, Warnhinweise und Vorsichtsmaßnahmen)

  • CalciumchloridMittelschwer

    Drugs That Increase the Risk of Hypercalcemia Increase frequency of monitoring of calcium concentrations in patients taking concomitant Calcium Chloride Injection and other drugs that increase the risk of hypercalcemia (e.g., calcipotriene, estrogen, lithium, parathyroid hormone, teriparatide, thiazide diuretics, Vitamin A, and Vitamin D). (Fachinformation zu Calciumchlorid, Arzneimittelwechselwirkungen)

  • Patients with elevated vitamin A levels may be at increased risk. (Fachinformation zu Elexacaftor, Tezacaftor und Ivacaftor, Warnhinweise und Vorsichtsmaßnahmen)

  • IvacaftorCYP3A4-HemmerMittelschwer

    Patients with elevated vitamin A levels may be at increased risk. (Fachinformation zu Ivacaftor, Warnhinweise und Vorsichtsmaßnahmen)

  • LomitapidMittelschwer

    Caution should be exercised when JUXTAPID is used with other medications known to have potential for hepatotoxicity, such as isotretinoin, amiodarone, acetaminophen (>4 g/day for ≥3 days/week), methotrexate, tetracyclines, and tamoxifen. (Fachinformation zu Lomitapid, Warnhinweise und Vorsichtsmaßnahmen)

  • MethotrexatImmunsuppressivumMittelschwer

    Monitor patients receiving XATMEP with other potential hepatotoxins (e.g., azathioprine, retinoids, and sulfasalazine) for possible signs of hepatotoxicity. (Fachinformation zu Methotrexat, Arzneimittelwechselwirkungen)

  • OrlistatMittelschwer

    The effect of ORLISTAT on the absorption of supplemental vitamin D, vitamin A, and nutritionally-derived vitamin K is not known at this time [see Clinical Pharmacology (12.3) , and Warnings and Precautions (5.1) ] . (Fachinformation zu Orlistat, Arzneimittelwechselwirkungen)

Geringfügige Erwähnungen (29)

  • AcetylsalicylsäureNSARGeringfügig

    Although the overall incidence of tartrazine sensitivity in the general population is low, it is frequently seen in patients who also have aspirin hypersensitivity. (Fachinformation zu Isotretinoin, Warnhinweise und Vorsichtsmaßnahmen)

  • Acetylsalicylsäure und DipyridamolThrombozytenaggregationshemmerGeringfügig

    Although the overall incidence of tartrazine sensitivity in the general population is low, it is frequently seen in patients who also have aspirin hypersensitivity. (Fachinformation zu Isotretinoin, Warnhinweise und Vorsichtsmaßnahmen)

  • Although the overall incidence of tartrazine sensitivity in the general population is low, it is frequently seen in patients who also have aspirin hypersensitivity. (Fachinformation zu Isotretinoin, Warnhinweise und Vorsichtsmaßnahmen)

  • Although the overall incidence of tartrazine sensitivity in the general population is low, it is frequently seen in patients who also have aspirin hypersensitivity. (Fachinformation zu Isotretinoin, Warnhinweise und Vorsichtsmaßnahmen)

  • CalciumgluconatGeringfügig

    Drugs that may cause hypercalcemia: Vitamin D, vitamin A, thiazide diuretics, estrogen, calcipotriene and teriparatide administration may cause hypercalcemia. (Fachinformation zu Calciumgluconat, Arzneimittelwechselwirkungen)

  • Desogestrel und Ethinylestradiolorales KontrazeptivumGeringfügig

    Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • Drospirenon und Ethinylestradiolorales KontrazeptivumGeringfügig

    Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • EstradiolEstrogenGeringfügig

    Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • Estradiol und Dienogestorales KontrazeptivumGeringfügig

    Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • Estradiol und NorethisteronEstrogenGeringfügig

    Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • Etynodioldiacetat und Ethinylestradiolorales KontrazeptivumGeringfügig

    Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • FluconazolAzol-AntimykotikumGeringfügig

    Vitamin A Based on a case report in one patient receiving combination therapy with all-trans-retinoid acid (an acid form of vitamin A) and fluconazole, central nervous system (CNS) related undesirable effects have developed in the form of pseudotumor cerebri, which disappeared after discontinuation of fluconazole treatment. (Fachinformation zu Fluconazol, Arzneimittelwechselwirkungen)

  • FulvestrantEstrogenGeringfügig

    Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • Konjugierte EstrogeneEstrogenGeringfügig

    Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • LevonorgestrelGestagenGeringfügig

    Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • Levonorgestrel und Ethinylestradiolorales KontrazeptivumGeringfügig

    Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • MedroxyprogesteronGestagenGeringfügig

    Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • MegestrolGestagenGeringfügig

    Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • MifepristonCYP3A4-HemmerGeringfügig

    Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • NorethisteronGestagenGeringfügig

    Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • Norethisteron und Ethinylestradiolorales KontrazeptivumGeringfügig

    Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • Norgestimat und Ethinylestradiolorales KontrazeptivumGeringfügig

    Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • Norgestrel und Ethinylestradiolorales KontrazeptivumGeringfügig

    Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • Although the overall incidence of tartrazine sensitivity in the general population is low, it is frequently seen in patients who also have aspirin hypersensitivity. (Fachinformation zu Isotretinoin, Warnhinweise und Vorsichtsmaßnahmen)

  • ProgesteronGestagenGeringfügig

    Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

  • Oral Contraceptives Isotretinoin Capsules did not result in clinically significant changes in the pharmacokinetics of norethindrone and ethinyl estradiol when used concomitantly with a norethindrone and ethinyl estradiol oral contraceptive [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Isotretinoin, Arzneimittelwechselwirkungen)

Prüfen Sie Isotretinoin gegen alles, was Sie einnehmen. Fügen Sie Ihre gesamte Liste hinzu; alle Paare werden auf einmal geprüft.

Im Wechselwirkungscheck öffnen

Keine medizinische Beratung. Der Schweregrad gibt die Formulierung der Fachinformation wieder, nicht Ihre persönlichen Umstände. Eine als „schwerwiegend“ eingestufte Wechselwirkung kann unter Aufsicht Routine sein, und eine „geringfügige“ kann bei hohen Dosen von Bedeutung sein. Fragen Sie in einer Apotheke nach.