Wechselwirkungen von Probenecid

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (Fachinformation zu Probenecid, Warnhinweise)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (Fachinformation zu Probenecid, Warnhinweise)

Co-administration with probenecid is not recommended. (Fachinformation zu Amoxicillin und Clavulansäure, Arzneimittelwechselwirkungen)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (Fachinformation zu Probenecid, Warnhinweise)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (Fachinformation zu Probenecid, Warnhinweise)

Thus, probenecid should not be administered concurrently with bumetanide. (Fachinformation zu Bumetanid, Arzneimittelwechselwirkungen)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (Fachinformation zu Probenecid, Warnhinweise)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (Fachinformation zu Probenecid, Warnhinweise)

Co-administration of probenecid with cephalexin for oral suspension is not recommended. (Fachinformation zu Cefalexin, Arzneimittelwechselwirkungen)

Co-administration of probenecid with Cefazolin for Injection is not recommended. (Fachinformation zu Cefazolin, Arzneimittelwechselwirkungen)

Administration of cefotaxime in excess of 6 grams/day should be avoided in patients receiving probenecid (see CLINICAL PHARMACOLOGY, Drug Interactions ). (Fachinformation zu Cefotaxim, Arzneimittelwechselwirkungen)

Coadministration with probenecid increases systemic exposure to cefuroxime axetil and is therefore not recommended. (Fachinformation zu Cefuroxim, Arzneimittelwechselwirkungen)

TO REDUCE POSSIBLE NEPHROTOXICITY, INTRAVENOUS PREHYDRATION WITH NORMAL SALINE AND ADMINISTRATION OF PROBENECID MUST BE USED WITH EACH CIDOFOVIR INFUSION. (Fachinformation zu Cidofovir, Boxed Warning (umrahmter Warnhinweis))

Effect of Other Drugs on FERRIPROX UDP-Glucuronosyltransferases (UGT) Avoid use of UGT1A6 inhibitors (e.g., diclofenac, probenecid, or silymarin (milk thistle)) with FERRIPROX [ see Dosage and Administration ( 2.2 ) , Adverse Reactions ( 6.1 ), Clinical Pharmacology ( 12.3 ) ] . (Fachinformation zu Deferipron, Arzneimittelwechselwirkungen)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (Fachinformation zu Probenecid, Warnhinweise)

Co-administration with probenecid inhibits the renal excretion of ertapenem and is therefore not recommended. (Fachinformation zu Ertapenem, Arzneimittelwechselwirkungen)

Therefore, it is not recommended that probenecid be given concomitantly with PRIMAXIN. (Fachinformation zu Imipenem und Cilastatin, Arzneimittelwechselwirkungen)

Therefore, the combination of ketoprofen and probenecid is not recommended. (Fachinformation zu Ketoprofen, Warnhinweise und Vorsichtsmaßnahmen)

The concomitant use of ketorolac tromethamine and probenecid is contraindicated. (Fachinformation zu Ketorolac, Gegenanzeigen)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (Fachinformation zu Probenecid, Warnhinweise)

Co-administration of Meropenem for injection with probenecid inhibits renal excretion of meropenem and is therefore not recommended ( 7.1 ) (Fachinformation zu Meropenem, Arzneimittelwechselwirkungen)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (Fachinformation zu Probenecid, Warnhinweise)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (Fachinformation zu Probenecid, Warnhinweise)

Probenecid prolongs the half-lives of piperacillin and tazobactam and should not be co-administered with Piperacillin and Tazobactam for Injection and Sodium Chloride Injection unless the benefit outweighs the risk. (Fachinformation zu Piperacillin und Tazobactam, Arzneimittelwechselwirkungen)

Avoid coadministration with probenecid or nonsteroidal anti-inflammatory drugs. (Fachinformation zu Pralatrexat, Arzneimittelwechselwirkungen)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (Fachinformation zu Probenecid, Warnhinweise)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (Fachinformation zu Probenecid, Warnhinweise)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Drug Interactions Coadministration of probenecid with intravenous acyclovir has been shown to increase the mean acyclovir half-life and the area under the concentration-time curve. (Fachinformation zu Aciclovir, Arzneimittelwechselwirkungen)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

In patients taking strong Organic Anion Transporter 3 (OAT3) inhibitors (e.g., probenecid) the recommended dosage should be reduced. (Fachinformation zu Baricitinib, Arzneimittelwechselwirkungen)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Therefore, CYCLOSET may increase the unbound fraction of other concomitantly used highly protein-bound therapies (e.g., salicylates, sulfonamides, chloramphenicol and probenecid), which may alter their effectiveness and risk for side effects. (Fachinformation zu Bromocriptin, Arzneimittelwechselwirkungen)

In patients on probenecid who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (Fachinformation zu Probenecid, Warnhinweise)

In patients on probenecid who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (Fachinformation zu Probenecid, Warnhinweise)

In patients on probenecid who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (Fachinformation zu Probenecid, Warnhinweise)

Monitor patients for increased toxicity when MRP2 inhibitors (e.g., abacavir, adefovir, cidofovir, furosemide, lamivudine, nevirapine, ritonavir, probenecid, saquinavir, and tenofovir) are co-administered with COMETRIQ [see Clinical Pharmacology ( 12.3 )] . (Fachinformation zu Cabozantinib, Arzneimittelwechselwirkungen)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Decrease ciprofloxacin absorption, resulting in lower serum and urine levels Probenecid Use with caution (interferes with renal tubular secretion of ciprofloxacin and increases ciprofloxacin serum levels) Potentiation of ciprofloxacin toxicity may occur. (Fachinformation zu Ciprofloxacin, Arzneimittelwechselwirkungen)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Probenecid: May increase penciclovir levels. (Fachinformation zu Famciclovir, Arzneimittelwechselwirkungen)

Probenecid ↑Ganciclovir Ganciclovir for Injection dose may need to be reduced. (Fachinformation zu Ganciclovir, Arzneimittelwechselwirkungen)

Probenecid may prolong or enhance the action of oral sulfonylureas and thereby increase the risk of hypoglycemia. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Probenecid may prolong or enhance the action of oral sulfonylureas and thereby increase the risk of hypoglycemia. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Probenecid may prolong or enhance the action of oral sulfonylureas and thereby increase the risk of hypoglycemia. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Probenecid may prolong or enhance the action of oral sulfonylureas and thereby increase the risk of hypoglycemia. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Probenecid may prolong or enhance the action of oral sulfonylureas and thereby increase the risk of hypoglycemia. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

In patients on probenecid who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (Fachinformation zu Probenecid, Warnhinweise)

Probenecid Clinical Impact: When indomethacin is given to patients receiving probenecid, the plasma levels of indomethacin are likely to be increased. (Fachinformation zu Indometacin, Arzneimittelwechselwirkungen)

In addition, ketamine and thiopental anesthesia were significantly prolonged in rats receiving probenecid. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Renal clearance of ucb L057 in the presence of probenecid decreased 60%, probably related to competitive inhibition of tubular secretion of ucb L057. (Fachinformation zu Levetiracetam, Arzneimittelwechselwirkungen)

However, these changes do not warrant dosage adjustment for Levofloxacin in 5% Dextrose Injection when probenecid or cimetidine is co-administered. (Fachinformation zu Levofloxacin, Arzneimittelwechselwirkungen)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Probenecid increases plasma concentrations of methotrexate in both animals and humans. (Fachinformation zu Probenecid, Warnhinweise)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Probenecid Clinical Impact: Probenecid given concurrently increases naproxen anion plasma levels and extends its plasma half-life significantly. (Fachinformation zu Naproxen, Arzneimittelwechselwirkungen)

Probenecid : May inhibit renal excretion of metabolites of PHEBURANE including phenylacetate and phenylacetylglutamine; monitor for potential neurotoxicity. (Fachinformation zu Natriumphenylbutyrat, Arzneimittelwechselwirkungen)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

In patients on probenecid who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (Fachinformation zu Probenecid, Warnhinweise)

In patients on probenecid who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (Fachinformation zu Probenecid, Warnhinweise)

In patients on probenecid who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (Fachinformation zu Probenecid, Warnhinweise)

In patients on probenecid who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (Fachinformation zu Probenecid, Warnhinweise)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Probenecid may prolong or enhance the action of oral sulfonylureas and thereby increase the risk of hypoglycemia. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Concomitant use with probenecid and cotrimoxazole increases the concentration of rifampin which may increase the risk of rifampin toxicities. (Fachinformation zu Rifampicin, Arzneimittelwechselwirkungen)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Probenecid given concomitantly with sulindac had only a slight effect on plasma sulfide levels, while plasma levels of sulindac and sulfone were increased. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Probenecid Clinical Impact: Probenecid given concurrently increases naproxen anion plasma levels and extends its plasma half-life significantly. (Fachinformation zu Sumatriptan und Naproxen, Arzneimittelwechselwirkungen)

Organic Anion Drugs Coadministration of organic anion drugs (e.g., probenecid) that undergo significant renal tubular secretion have the potential to reduce secretion of torsemide into the proximal tubule and thereby decreases the diuretic activity of torsemide. (Fachinformation zu Torasemid, Arzneimittelwechselwirkungen)

In patients on probenecid who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (Fachinformation zu Probenecid, Warnhinweise)

Didanosine ↔ Ganciclovir ↑ Didanosine Patients should be closely monitored for didanosine toxicity (e.g., pancreatitis) Probenecid ↑ Ganciclovir Valganciclovir hydrochloride dose may need to be reduced. (Fachinformation zu Valganciclovir, Arzneimittelwechselwirkungen)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Falsely high readings for theophylline have been reported in an in vitro study, using the Schack and Waxler technique, when therapeutic concentrations of theophylline and probenecid were added to human plasma. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Falsely high readings for theophylline have been reported in an in vitro study, using the Schack and Waxler technique, when therapeutic concentrations of theophylline and probenecid were added to human plasma. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

These include probenecid, cholestyramine, and some antibiotics (e.g., erythromycin, rifampicin, ampicillin and chloramphenicol). (Fachinformation zu Carbidopa, Levodopa und Entacapon, Arzneimittelwechselwirkungen)

WARNINGS Exacerbation of gout following therapy with probenecid may occur; in such cases colchicine or other appropriate therapy is advisable. (Fachinformation zu Probenecid, Warnhinweise)

These include probenecid, cholestyramine, and some antibiotics (e.g., erythromycin, rifampicin, ampicillin, and chloramphenicol). (Fachinformation zu Entacapon, Vorsichtsmaßnahmen)

Falsely high readings for theophylline have been reported in an in vitro study, using the Schack and Waxler technique, when therapeutic concentrations of theophylline and probenecid were added to human plasma. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Falsely high readings for theophylline have been reported in an in vitro study, using the Schack and Waxler technique, when therapeutic concentrations of theophylline and probenecid were added to human plasma. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Probenecid Probenecid is a blocker of renal tubular secretion. (Fachinformation zu Gabapentin, Arzneimittelwechselwirkungen)

Probenecid : May affect renal excretion of metabolites of glycerol phenylbutyrate, including phenylacetylglutamine (PAGN) and PAA. (Fachinformation zu Glycerolphenylbutyrat, Arzneimittelwechselwirkungen)

These include agents such as indomethacin, acetaminophen, naproxen, ketoprofen, meclofenamate, lorazepam, and rifampin. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

These include agents such as indomethacin, acetaminophen, naproxen, ketoprofen, meclofenamate, lorazepam, and rifampin. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Probenecid is known to inhibit the renal transport of many organic compounds, including aminohippuric acid, and may affect renal excretion of phenylacetylglutamine and hippurate. (Fachinformation zu Natriumphenylacetat und Natriumbenzoat, Arzneimittelwechselwirkungen)

Uricosuric Drugs Uricosuric drugs, such as probenecid and sulfinpyrazone, can inhibit renal tubular secretion of nitrofurantoin. (Fachinformation zu Nitrofurantoin, Arzneimittelwechselwirkungen)

Probenecid The concomitant use of probenecid with certain other quinolones has been reported to affect renal tubular secretion. (Fachinformation zu Ofloxacin, Arzneimittelwechselwirkungen)

Falsely high readings for theophylline have been reported in an in vitro study, using the Schack and Waxler technique, when therapeutic concentrations of theophylline and probenecid were added to human plasma. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

…hypoglycemics–insulin, chlorpropamide, phenformin, tolazamide, and tolbutamide; (3) tranquilizers and sedatives–chlordiazepoxide, diazepam, and phenobarbital; (4) antigout–allopurinol, colchicine, and probenecid; (5) antiarrhythmics–procainamide, propranolol (see WARNINGS however), and quinidine; and (6) analgesics, antipyretics and anti-inflammatories–propoxyphene, aspirin, indomethacin,… (Fachinformation zu Prazosin, Arzneimittelwechselwirkungen)

The uricosuric action of probenecid is also antagonized by pyrazinamide. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Falsely high readings for theophylline have been reported in an in vitro study, using the Schack and Waxler technique, when therapeutic concentrations of theophylline and probenecid were added to human plasma. (Fachinformation zu Probenecid, Arzneimittelwechselwirkungen)

Probenecid does not affect renal tubular transport of gentamicin. (Fachinformation zu Gentamicin, Arzneimittelwechselwirkungen)

Examples Acyclovir, ganciclovir, probenecid, valacyclovir, valganciclovir Combination Oral Contraceptives Clinical Impact Concomitant use with mycophenolate mofetil decreased the systemic exposure to levonorgestrel, but did not affect the systemic exposure to ethinylestradiol [see Clinical Pharmacology ( 12.3 )], which may result in reduced combination oral contraceptive… (Fachinformation zu Mycophenolat, Arzneimittelwechselwirkungen)