Interacciones de Probenecid

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (etiqueta de Probenecid, Advertencias)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (etiqueta de Probenecid, Advertencias)

Co-administration with probenecid is not recommended. (etiqueta de Amoxicilina y ácido clavulánico, Interacciones medicamentosas)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (etiqueta de Probenecid, Advertencias)

Thus, probenecid should not be administered concurrently with bumetanide. (etiqueta de Bumetanida, Interacciones medicamentosas)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (etiqueta de Probenecid, Advertencias)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (etiqueta de Probenecid, Advertencias)

Co-administration of probenecid with cephalexin for oral suspension is not recommended. (etiqueta de Cefalexina, Interacciones medicamentosas)

Co-administration of probenecid with Cefazolin for Injection is not recommended. (etiqueta de Cefazolina, Interacciones medicamentosas)

Administration of cefotaxime in excess of 6 grams/day should be avoided in patients receiving probenecid (see CLINICAL PHARMACOLOGY, Drug Interactions ). (etiqueta de Cefotaxima, Interacciones medicamentosas)

Coadministration with probenecid increases systemic exposure to cefuroxime axetil and is therefore not recommended. (etiqueta de Cefuroxima, Interacciones medicamentosas)

TO REDUCE POSSIBLE NEPHROTOXICITY, INTRAVENOUS PREHYDRATION WITH NORMAL SALINE AND ADMINISTRATION OF PROBENECID MUST BE USED WITH EACH CIDOFOVIR INFUSION. (etiqueta de Cidofovir, Advertencia en recuadro)

Effect of Other Drugs on FERRIPROX UDP-Glucuronosyltransferases (UGT) Avoid use of UGT1A6 inhibitors (e.g., diclofenac, probenecid, or silymarin (milk thistle)) with FERRIPROX [ see Dosage and Administration ( 2.2 ) , Adverse Reactions ( 6.1 ), Clinical Pharmacology ( 12.3 ) ] . (etiqueta de Deferiprona, Interacciones medicamentosas)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (etiqueta de Probenecid, Advertencias)

Co-administration with probenecid inhibits the renal excretion of ertapenem and is therefore not recommended. (etiqueta de Ertapenem, Interacciones medicamentosas)

Therefore, it is not recommended that probenecid be given concomitantly with PRIMAXIN. (etiqueta de Imipenem y cilastatina, Interacciones medicamentosas)

Therefore, the combination of ketoprofen and probenecid is not recommended. (etiqueta de Ketoprofeno, Advertencias y precauciones)

The concomitant use of ketorolac tromethamine and probenecid is contraindicated. (etiqueta de Ketorolaco, Contraindicaciones)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (etiqueta de Probenecid, Advertencias)

Co-administration of Meropenem for injection with probenecid inhibits renal excretion of meropenem and is therefore not recommended ( 7.1 ) (etiqueta de Meropenem, Interacciones medicamentosas)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (etiqueta de Probenecid, Advertencias)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (etiqueta de Probenecid, Advertencias)

Probenecid prolongs the half-lives of piperacillin and tazobactam and should not be co-administered with Piperacillin and Tazobactam for Injection and Sodium Chloride Injection unless the benefit outweighs the risk. (etiqueta de Piperacilina y tazobactam, Interacciones medicamentosas)

Avoid coadministration with probenecid or nonsteroidal anti-inflammatory drugs. (etiqueta de Pralatrexato, Interacciones medicamentosas)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (etiqueta de Probenecid, Advertencias)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (etiqueta de Probenecid, Advertencias)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (etiqueta de Probenecid, Advertencias)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (etiqueta de Probenecid, Interacciones medicamentosas)

Drug Interactions Coadministration of probenecid with intravenous acyclovir has been shown to increase the mean acyclovir half-life and the area under the concentration-time curve. (etiqueta de Aciclovir, Interacciones medicamentosas)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

In patients taking strong Organic Anion Transporter 3 (OAT3) inhibitors (e.g., probenecid) the recommended dosage should be reduced. (etiqueta de Baricitinib, Interacciones medicamentosas)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (etiqueta de Probenecid, Interacciones medicamentosas)

Therefore, CYCLOSET may increase the unbound fraction of other concomitantly used highly protein-bound therapies (e.g., salicylates, sulfonamides, chloramphenicol and probenecid), which may alter their effectiveness and risk for side effects. (etiqueta de Bromocriptina, Interacciones medicamentosas)

In patients on probenecid who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (etiqueta de Probenecid, Advertencias)

In patients on probenecid who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (etiqueta de Probenecid, Advertencias)

In patients on probenecid who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (etiqueta de Probenecid, Advertencias)

Monitor patients for increased toxicity when MRP2 inhibitors (e.g., abacavir, adefovir, cidofovir, furosemide, lamivudine, nevirapine, ritonavir, probenecid, saquinavir, and tenofovir) are co-administered with COMETRIQ [see Clinical Pharmacology ( 12.3 )] . (etiqueta de Cabozantinib, Interacciones medicamentosas)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

Decrease ciprofloxacin absorption, resulting in lower serum and urine levels Probenecid Use with caution (interferes with renal tubular secretion of ciprofloxacin and increases ciprofloxacin serum levels) Potentiation of ciprofloxacin toxicity may occur. (etiqueta de Ciprofloxacino, Interacciones medicamentosas)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (etiqueta de Probenecid, Interacciones medicamentosas)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (etiqueta de Probenecid, Interacciones medicamentosas)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (etiqueta de Probenecid, Interacciones medicamentosas)

Probenecid: May increase penciclovir levels. (etiqueta de Famciclovir, Interacciones medicamentosas)

Probenecid : May inhibit renal excretion of metabolites of PHEBURANE including phenylacetate and phenylacetylglutamine; monitor for potential neurotoxicity. (etiqueta de Fenilbutirato de sodio, Interacciones medicamentosas)

Probenecid ↑Ganciclovir Ganciclovir for Injection dose may need to be reduced. (etiqueta de Ganciclovir, Interacciones medicamentosas)

Probenecid may prolong or enhance the action of oral sulfonylureas and thereby increase the risk of hypoglycemia. (etiqueta de Probenecid, Interacciones medicamentosas)

Probenecid may prolong or enhance the action of oral sulfonylureas and thereby increase the risk of hypoglycemia. (etiqueta de Probenecid, Interacciones medicamentosas)

Probenecid may prolong or enhance the action of oral sulfonylureas and thereby increase the risk of hypoglycemia. (etiqueta de Probenecid, Interacciones medicamentosas)

Probenecid may prolong or enhance the action of oral sulfonylureas and thereby increase the risk of hypoglycemia. (etiqueta de Probenecid, Interacciones medicamentosas)

Probenecid may prolong or enhance the action of oral sulfonylureas and thereby increase the risk of hypoglycemia. (etiqueta de Probenecid, Interacciones medicamentosas)

In patients on probenecid who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (etiqueta de Probenecid, Advertencias)

Probenecid Clinical Impact: When indomethacin is given to patients receiving probenecid, the plasma levels of indomethacin are likely to be increased. (etiqueta de Indometacina, Interacciones medicamentosas)

In addition, ketamine and thiopental anesthesia were significantly prolonged in rats receiving probenecid. (etiqueta de Probenecid, Interacciones medicamentosas)

Renal clearance of ucb L057 in the presence of probenecid decreased 60%, probably related to competitive inhibition of tubular secretion of ucb L057. (etiqueta de Levetiracetam, Interacciones medicamentosas)

However, these changes do not warrant dosage adjustment for Levofloxacin in 5% Dextrose Injection when probenecid or cimetidine is co-administered. (etiqueta de Levofloxacino, Interacciones medicamentosas)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (etiqueta de Probenecid, Interacciones medicamentosas)

Probenecid increases plasma concentrations of methotrexate in both animals and humans. (etiqueta de Probenecid, Advertencias)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

Probenecid Clinical Impact: Probenecid given concurrently increases naproxen anion plasma levels and extends its plasma half-life significantly. (etiqueta de Naproxeno, Interacciones medicamentosas)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

In patients on probenecid who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (etiqueta de Probenecid, Advertencias)

In patients on probenecid who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (etiqueta de Probenecid, Advertencias)

In patients on probenecid who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (etiqueta de Probenecid, Advertencias)

In patients on probenecid who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (etiqueta de Probenecid, Advertencias)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (etiqueta de Probenecid, Interacciones medicamentosas)

Probenecid may prolong or enhance the action of oral sulfonylureas and thereby increase the risk of hypoglycemia. (etiqueta de Probenecid, Interacciones medicamentosas)

Concomitant use with probenecid and cotrimoxazole increases the concentration of rifampin which may increase the risk of rifampin toxicities. (etiqueta de Rifampicina, Interacciones medicamentosas)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (etiqueta de Probenecid, Interacciones medicamentosas)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (etiqueta de Probenecid, Interacciones medicamentosas)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (etiqueta de Probenecid, Interacciones medicamentosas)

Probenecid given concomitantly with sulindac had only a slight effect on plasma sulfide levels, while plasma levels of sulindac and sulfone were increased. (etiqueta de Probenecid, Interacciones medicamentosas)

Probenecid Clinical Impact: Probenecid given concurrently increases naproxen anion plasma levels and extends its plasma half-life significantly. (etiqueta de Sumatriptán y naproxeno, Interacciones medicamentosas)

Organic Anion Drugs Coadministration of organic anion drugs (e.g., probenecid) that undergo significant renal tubular secretion have the potential to reduce secretion of torsemide into the proximal tubule and thereby decreases the diuretic activity of torsemide. (etiqueta de Torasemida, Interacciones medicamentosas)

In patients on probenecid who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (etiqueta de Probenecid, Advertencias)

Didanosine ↔ Ganciclovir ↑ Didanosine Patients should be closely monitored for didanosine toxicity (e.g., pancreatitis) Probenecid ↑ Ganciclovir Valganciclovir hydrochloride dose may need to be reduced. (etiqueta de Valganciclovir, Interacciones medicamentosas)

Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (etiqueta de Probenecid, Interacciones medicamentosas)

Falsely high readings for theophylline have been reported in an in vitro study, using the Schack and Waxler technique, when therapeutic concentrations of theophylline and probenecid were added to human plasma. (etiqueta de Probenecid, Interacciones medicamentosas)

Falsely high readings for theophylline have been reported in an in vitro study, using the Schack and Waxler technique, when therapeutic concentrations of theophylline and probenecid were added to human plasma. (etiqueta de Probenecid, Interacciones medicamentosas)

These include probenecid, cholestyramine, and some antibiotics (e.g., erythromycin, rifampicin, ampicillin and chloramphenicol). (etiqueta de Carbidopa, levodopa y entacapona, Interacciones medicamentosas)

WARNINGS Exacerbation of gout following therapy with probenecid may occur; in such cases colchicine or other appropriate therapy is advisable. (etiqueta de Probenecid, Advertencias)

These include probenecid, cholestyramine, and some antibiotics (e.g., erythromycin, rifampicin, ampicillin, and chloramphenicol). (etiqueta de Entacapona, Precauciones)

Falsely high readings for theophylline have been reported in an in vitro study, using the Schack and Waxler technique, when therapeutic concentrations of theophylline and probenecid were added to human plasma. (etiqueta de Probenecid, Interacciones medicamentosas)

Falsely high readings for theophylline have been reported in an in vitro study, using the Schack and Waxler technique, when therapeutic concentrations of theophylline and probenecid were added to human plasma. (etiqueta de Probenecid, Interacciones medicamentosas)

Probenecid is known to inhibit the renal transport of many organic compounds, including aminohippuric acid, and may affect renal excretion of phenylacetylglutamine and hippurate. (etiqueta de Fenilacetato de sodio y benzoato de sodio, Interacciones medicamentosas)

Probenecid : May affect renal excretion of metabolites of glycerol phenylbutyrate, including phenylacetylglutamine (PAGN) and PAA. (etiqueta de Fenilbutirato de glicerol, Interacciones medicamentosas)

Probenecid Probenecid is a blocker of renal tubular secretion. (etiqueta de Gabapentina, Interacciones medicamentosas)

These include agents such as indomethacin, acetaminophen, naproxen, ketoprofen, meclofenamate, lorazepam, and rifampin. (etiqueta de Probenecid, Interacciones medicamentosas)

These include agents such as indomethacin, acetaminophen, naproxen, ketoprofen, meclofenamate, lorazepam, and rifampin. (etiqueta de Probenecid, Interacciones medicamentosas)

Uricosuric Drugs Uricosuric drugs, such as probenecid and sulfinpyrazone, can inhibit renal tubular secretion of nitrofurantoin. (etiqueta de Nitrofurantoína, Interacciones medicamentosas)

Probenecid The concomitant use of probenecid with certain other quinolones has been reported to affect renal tubular secretion. (etiqueta de Ofloxacino, Interacciones medicamentosas)

Falsely high readings for theophylline have been reported in an in vitro study, using the Schack and Waxler technique, when therapeutic concentrations of theophylline and probenecid were added to human plasma. (etiqueta de Probenecid, Interacciones medicamentosas)

The uricosuric action of probenecid is also antagonized by pyrazinamide. (etiqueta de Probenecid, Interacciones medicamentosas)

…hypoglycemics–insulin, chlorpropamide, phenformin, tolazamide, and tolbutamide; (3) tranquilizers and sedatives–chlordiazepoxide, diazepam, and phenobarbital; (4) antigout–allopurinol, colchicine, and probenecid; (5) antiarrhythmics–procainamide, propranolol (see WARNINGS however), and quinidine; and (6) analgesics, antipyretics and anti-inflammatories–propoxyphene, aspirin, indomethacin,… (etiqueta de Prazosina, Interacciones medicamentosas)

Falsely high readings for theophylline have been reported in an in vitro study, using the Schack and Waxler technique, when therapeutic concentrations of theophylline and probenecid were added to human plasma. (etiqueta de Probenecid, Interacciones medicamentosas)

Probenecid does not affect renal tubular transport of gentamicin. (etiqueta de Gentamicina, Interacciones medicamentosas)

Examples Acyclovir, ganciclovir, probenecid, valacyclovir, valganciclovir Combination Oral Contraceptives Clinical Impact Concomitant use with mycophenolate mofetil decreased the systemic exposure to levonorgestrel, but did not affect the systemic exposure to ethinylestradiol [see Clinical Pharmacology ( 12.3 )], which may result in reduced combination oral contraceptive… (etiqueta de Micofenolato, Interacciones medicamentosas)