Interaction Checker

Interacciones de Bortezomib

Bortezomib (Velcade) tiene 204 interacciones documentadas en las etiquetas de la FDA y las hojas informativas que indexamos. Graves: 33; moderadas: 163; leves: 5; casos en los que una etiqueta indica que no hay ninguna interacción significativa: 3. Cada entrada de abajo cita la frase que la respalda. Esta página del medicamento es un punto de partida, no un veredicto sobre su situación.

Interacciones según la etiqueta

Interacciones graves (33)

  • Aprepitantinhibidor de CYP3A4Grave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Armodafiniloestimulante del SNCGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Bosentáninductor de CYP3A4Grave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • CarbamazepinaanticonvulsivoGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • CenobamatoanticonvulsivoGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • ClobazambenzodiazepinaGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Deferasiroxsuplemento de hierroGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • DexametasonacorticosteroideGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • EfavirenzantirretroviralGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Efavirenz, lamivudina y tenofovirantirretroviralGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • EslicarbazepinaanticonvulsivoGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • EtravirinaantirretroviralGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • FenitoínaanticonvulsivoGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • FenobarbitalbarbitúricoGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Fentermina y topiramatoestimulante del SNCGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • FosfenitoínaanticonvulsivoGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • GriseofulvinaantifúngicoGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Ketoconazolantifúngico azólicoGrave

    …caution with ketoconazole, and specifically, should not be used within at least 72 hours of treatment with ketoconazole Antineoplastics irinotecan dasatinib, lapatinib, nilotinib bortezomib, busulphan, docetaxel, erlotinib, imatinib, ixabepilone, paclitaxel, trimetrexate, vinca alkaloids Irinotecan: The potential increase in plasma concentrations of irinotecan… (etiqueta de Ketoconazol, Interacciones medicamentosas)

  • Lopinavir y ritonavirantirretroviralGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Lorlatinibinductor de CYP3A4Grave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Mitapivatinductor de CYP3A4Grave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Mitotanoinductor de CYP3A4Grave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Modafiniloestimulante del SNCGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Nafcilinaantibiótico del grupo de las penicilinasGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • NevirapinaantirretroviralGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • OxcarbazepinaanticonvulsivoGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • PrimidonaanticonvulsivoGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • RifabutinaantibióticoGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • RifampicinaantibióticoGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • RifapentinaantibióticoGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • RitonavirantirretroviralGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Suzetriginainductor de CYP3A4Grave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • TopiramatoanticonvulsivoGrave

    Strong CYP3A4 Inducers: Avoid concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

Interacciones moderadas (163)

  • AcebutololbetabloqueanteModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Ácido etacrínicodiurético de asaModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • AdrenalinasimpaticomiméticoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • AliskirenoantihipertensivoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Amiloridadiurético ahorrador de potasioModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • AmiodaronaantiarrítmicoModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Amlodipinobloqueador de los canales de calcio dihidropiridínicoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Amlodipino y atorvastatinabloqueador de los canales de calcio dihidropiridínicoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Amlodipino y benazeprilbloqueador de los canales de calcio dihidropiridínicoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Amlodipino y olmesartánbloqueador de los canales de calcio dihidropiridínicoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Amlodipino y valsartánbloqueador de los canales de calcio dihidropiridínicoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Anfepramonaestimulante del SNCModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Anfetaminaestimulante del SNCModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Anfetamina y dexanfetaminaestimulante del SNCModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Arformoterolagonista beta-adrenérgicoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Articaína y adrenalinaanestésico localModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • AtazanavirantirretroviralModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • AtenololbetabloqueanteModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Atenolol y clortalidonabetabloqueanteModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Azilsartánantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Benazeprilinhibidor de la ECAModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Benazepril e hidroclorotiazidainhibidor de la ECAModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Benzfetaminaestimulante del SNCModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • BetaxololbetabloqueanteModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • BisoprololbetabloqueanteModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Bisoprolol e hidroclorotiazidabetabloqueanteModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Bromfeniramina, pseudoefedrina y dextrometorfanoantihistamínicoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Budesonida y formoterolcorticosteroideModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Bupivacaína y adrenalinaanestésico localModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Butalbital, ácido acetilsalicílico y cafeínabarbitúricoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Butalbital, ácido acetilsalicílico, cafeína y codeínabarbitúricoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Butalbital, paracetamol y cafeínabarbitúricoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Butalbital, paracetamol, cafeína y codeínabarbitúricoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Candesartánantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Candesartán e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Captoprilinhibidor de la ECAModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • CarvedilolbetabloqueanteModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • CiclosporinainmunosupresorModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Cimetidinaantagonista H2Moderada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • CitarabinaantimetabolitoModerada

    In a clinical trial, the first two patients given high-dose cytarabine (2 g/m 2 per day) by continuous infusion with daunorubicin and bortezomib for relapsed acute myelogenous leukemia died of ARDS early in the course of therapy. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Claritromicinaantibiótico macrólidoModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Clonidinaagonista alfa-adrenérgicoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Clorotiazidadiurético tiazídicoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Clortalidonadiurético tiazídicoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • DarunavirantirretroviralModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Darunavir y cobicistatantirretroviralModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • DaunorubicinaModerada

    In a clinical trial, the first two patients given high-dose cytarabine (2 g/m 2 per day) by continuous infusion with daunorubicin and bortezomib for relapsed acute myelogenous leukemia died of ARDS early in the course of therapy. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Dexanfetaminaestimulante del SNCModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Dexmetilfenidatoestimulante del SNCModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Diltiazembloqueador de los canales de calcioModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Dinitrato de isosorbida e hidralazinanitratoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • DobutaminasimpaticomiméticoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • DoxazosinaalfabloqueanteModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • DronedaronaantiarrítmicoModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • DroxidopasimpaticomiméticoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • EfedrinasimpaticomiméticoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Elvitegravir, cobicistat, emtricitabina y tenofovirantirretroviralModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Enalaprilinhibidor de la ECAModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Enalapril e hidroclorotiazidainhibidor de la ECAModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Enalaprilatoinhibidor de la ECAModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Eplerenonaantagonista de la aldosteronaModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Ergotamina y cafeínaalcaloide ergóticoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Eritromicinaantibiótico macrólidoModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Espironolactonaantagonista de la aldosteronaModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Espironolactona e hidroclorotiazidaantagonista de la aldosteronaModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • EverolimusinmunosupresorModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Felodipinobloqueador de los canales de calcio dihidropiridínicoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Fendimetrazinaestimulante del SNCModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • FenilefrinadescongestionanteModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • FenoxibenzaminaalfabloqueanteModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Fenterminaestimulante del SNCModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Fluconazolantifúngico azólicoModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • FludrocortisonacorticosteroideModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Fluticasona y salmeterolcorticosteroideModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Formoterolagonista beta-adrenérgicoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • FosamprenavirantirretroviralModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Fosaprepitantinhibidor de CYP3A4Moderada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Fosinoprilinhibidor de la ECAModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Fosinopril e hidroclorotiazidainhibidor de la ECAModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Furosemidadiurético de asaModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Guanfacinaagonista alfa-adrenérgicoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • HidralazinavasodilatadorModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Hidroclorotiazidadiurético tiazídicoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Imatinibinhibidor de CYP3A4Moderada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Indapamidadiurético tiazídicoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Ipratropio y salbutamolanticolinérgicoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Irbesartánantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Irbesartán e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • IsoniazidaantibióticoModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Isoprenalina (isoproterenol)agonista beta-adrenérgicoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Isradipinobloqueador de los canales de calcio dihidropiridínicoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Itraconazolantifúngico azólicoModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Ivacaftorinhibidor de CYP3A4Moderada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • LabetalolbetabloqueanteModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • LenacapavirantirretroviralModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Levosalbutamolagonista beta-adrenérgicoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Lidocaína y adrenalinaanestésico localModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Lisdexanfetaminaestimulante del SNCModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Lisinoprilinhibidor de la ECAModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Lisinopril e hidroclorotiazidainhibidor de la ECAModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Lofexidinaagonista alfa-adrenérgicoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Losartánantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Losartán e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • MecamilaminaantihipertensivoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Metanfetaminaestimulante del SNCModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • MetildopaantihipertensivoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Metilfenidatoestimulante del SNCModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Metolazonadiurético tiazídicoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • MetoprololbetabloqueanteModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Metoprolol e hidroclorotiazidabetabloqueanteModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Midodrinaagonista alfa-adrenérgicoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Mifepristonainhibidor de CYP3A4Moderada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • MinoxidilvasodilatadorModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Mirabegrónagonista beta-adrenérgicoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Moexiprilinhibidor de la ECAModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • NadololbetabloqueanteModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • NebivololbetabloqueanteModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • NefazodonaantidepresivoModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Nicardipinobloqueador de los canales de calcio dihidropiridínicoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Nifedipinobloqueador de los canales de calcio dihidropiridínicoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Nirmatrelvir y ritonavirantiviralModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Nisoldipinobloqueador de los canales de calcio dihidropiridínicoModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • NitroprusiatovasodilatadorModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Olmesartánantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Olmesartán e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Olmesartán, amlodipino e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Orfenadrina, ácido acetilsalicílico y cafeínarelajante muscularModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • OximetazolinadescongestionanteModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Palbociclibinhibidor de CYP3A4Moderada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • PerampanelanticonvulsivoModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Perindoprilinhibidor de la ECAModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • PindololbetabloqueanteModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Posaconazolantifúngico azólicoModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • PrazosinaalfabloqueanteModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Prilocaína y adrenalinaanestésico localModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • PropranololbetabloqueanteModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • PseudoefedrinadescongestionanteModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Quinaprilinhibidor de la ECAModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Quinapril e hidroclorotiazidainhibidor de la ECAModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Ramiprilinhibidor de la ECAModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Ranolazinafármaco que prolonga el intervalo QTModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Sacubitrilo y valsartánantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Salbutamolagonista beta-adrenérgicoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Salmeterolagonista beta-adrenérgicoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Solriamfetolestimulante del SNCModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Suvorexantsedante-hipnóticoModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Telmisartánantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Telmisartán e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Telmisartán y amlodipinoantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • TerazosinaalfabloqueanteModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Terbutalinaagonista beta-adrenérgicoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Ticagrelorantiagregante plaquetarioModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Tizanidinarelajante muscularModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Torasemidadiurético de asaModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Trandolaprilinhibidor de la ECAModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Triamterenodiurético ahorrador de potasioModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Triamtereno e hidroclorotiazidadiurético ahorrador de potasioModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Umeclidinio y vilanterolanticolinérgicoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Valsartánantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Valsartán e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Verapamilobloqueador de los canales de calcioModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Vibegrónagonista beta-adrenérgicoModerada

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (etiqueta de Bortezomib, Advertencias y precauciones)

  • Voriconazolantifúngico azólicoModerada

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (etiqueta de Bortezomib, Interacciones medicamentosas)

Menciones leves (5)

  • CiclofosfamidainmunosupresorLeve

    …* A baseline platelet count of 50,000/μL was required for study eligibility ‡ Data were missing at baseline for one patient In the combination study of bortezomib with rituximab, cyclophosphamide, doxorubicin and prednisone (BR-CAP) in previously untreated mantle cell lymphoma patients, the incidence of thrombocytopenia (≥ Grade 4) was 32% vs 1% for the rituximab,… (etiqueta de Bortezomib, Advertencias y precauciones)

  • DoxorubicinaLeve

    …platelet count of 50,000/μL was required for study eligibility ‡ Data were missing at baseline for one patient In the combination study of bortezomib with rituximab, cyclophosphamide, doxorubicin and prednisone (BR-CAP) in previously untreated mantle cell lymphoma patients, the incidence of thrombocytopenia (≥ Grade 4) was 32% vs 1% for the rituximab, cyclophosphamide,… (etiqueta de Bortezomib, Advertencias y precauciones)

  • PrednisonacorticosteroideLeve

    …50,000/μL was required for study eligibility ‡ Data were missing at baseline for one patient In the combination study of bortezomib with rituximab, cyclophosphamide, doxorubicin and prednisone (BR-CAP) in previously untreated mantle cell lymphoma patients, the incidence of thrombocytopenia (≥ Grade 4) was 32% vs 1% for the rituximab, cyclophosphamide, doxorubicin,… (etiqueta de Bortezomib, Advertencias y precauciones)

  • RituximabinmunosupresorLeve

    …(14%) 5 (71%) * A baseline platelet count of 50,000/μL was required for study eligibility ‡ Data were missing at baseline for one patient In the combination study of bortezomib with rituximab, cyclophosphamide, doxorubicin and prednisone (BR-CAP) in previously untreated mantle cell lymphoma patients, the incidence of thrombocytopenia (≥ Grade 4) was 32% vs 1% for… (etiqueta de Bortezomib, Advertencias y precauciones)

  • VincristinaLeve

    …baseline for one patient In the combination study of bortezomib with rituximab, cyclophosphamide, doxorubicin and prednisone (BR-CAP) in previously untreated mantle cell lymphoma patients, the incidence of thrombocytopenia (≥ Grade 4) was 32% vs 1% for the rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) arm as shown in Table 12 . (etiqueta de Bortezomib, Advertencias y precauciones)

Sin interacción significativa según la etiqueta (3)

  • MelfalánSin interacción

    Drugs Without Clinically Significant Interactions with Bortezomib No clinically significant drug interactions have been observed when bortezomib was coadministered with dexamethasone, omeprazole, or melphalan in combination with prednisone [see Clinical Pharmacology (12.3) ] . (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Omeprazolinhibidor de la bomba de protonesSin interacción

    Drugs Without Clinically Significant Interactions with Bortezomib No clinically significant drug interactions have been observed when bortezomib was coadministered with dexamethasone, omeprazole, or melphalan in combination with prednisone [see Clinical Pharmacology (12.3) ] . (etiqueta de Bortezomib, Interacciones medicamentosas)

  • Omeprazol y bicarbonato de sodioinhibidor de la bomba de protonesSin interacción

    Drugs Without Clinically Significant Interactions with Bortezomib No clinically significant drug interactions have been observed when bortezomib was coadministered with dexamethasone, omeprazole, or melphalan in combination with prednisone [see Clinical Pharmacology (12.3) ] . (etiqueta de Bortezomib, Interacciones medicamentosas)

Compruebe Bortezomib frente a todo lo que toma. Añada su lista completa; todos los pares se comprueban a la vez.

Abrir en el verificador

No es un consejo médico. La gravedad refleja la redacción de la etiqueta, no sus circunstancias. Una señal «grave» puede ser algo habitual bajo supervisión y una «leve» puede ser importante a dosis altas. Consulte a un farmacéutico.