Interaction Checker

Interaksi Bortezomib

Bortezomib (Velcade) memiliki 204 interaksi terdokumentasi dalam label FDA dan lembar fakta yang kami indeks: 33 mayor, 163 moderat, 5 minor, dan 3 dengan label yang melaporkan tidak ada interaksi bermakna. Setiap entri di bawah ini mengutip kalimat yang mendasarinya. Halaman obat ini adalah titik awal, bukan putusan untuk situasi Anda.

Interaksi dari label

Interaksi mayor (33)

  • Aprepitantpenghambat CYP3A4Mayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • Armodafinilstimulan SSPMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • Bosentanpenginduksi CYP3A4Mayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • Deferasirokssuplemen zat besiMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • DeksametasonkortikosteroidMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • EfavirenzantiretroviralMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • Efavirenz, lamivudin, dan tenofovirantiretroviralMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • EslikarbazepinantikonvulsanMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • EtravirinantiretroviralMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • FenitoinantikonvulsanMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • FenobarbitalbarbituratMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • Fentermin dan topiramatstimulan SSPMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • FosfenitoinantikonvulsanMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • GriseofulvinantijamurMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • KarbamazepinantikonvulsanMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • Ketokonazolantijamur azolMayor

    …caution with ketoconazole, and specifically, should not be used within at least 72 hours of treatment with ketoconazole Antineoplastics irinotecan dasatinib, lapatinib, nilotinib bortezomib, busulphan, docetaxel, erlotinib, imatinib, ixabepilone, paclitaxel, trimetrexate, vinca alkaloids Irinotecan: The potential increase in plasma concentrations of irinotecan… (label Ketokonazol, Interaksi obat)

  • KlobazambenzodiazepinMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • Lopinavir dan ritonavirantiretroviralMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • Lorlatinibpenginduksi CYP3A4Mayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • Mitapivatpenginduksi CYP3A4Mayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • Mitotanpenginduksi CYP3A4Mayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • Modafinilstimulan SSPMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • Nafsilinantibiotik penisilinMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • NevirapinantiretroviralMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • OkskarbazepinantikonvulsanMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • PrimidonantikonvulsanMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • RifabutinantibiotikMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • RifampisinantibiotikMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • RifapentinantibiotikMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • RitonavirantiretroviralMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • SenobamatantikonvulsanMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • Suzetriginpenginduksi CYP3A4Mayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

  • TopiramatantikonvulsanMayor

    Strong CYP3A4 Inducers: Avoid concomitant use. (label Bortezomib, Interaksi obat)

Interaksi moderat (163)

  • AliskirenantihipertensiModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Amfetaminstimulan SSPModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Amfetamin dan dekstroamfetaminstimulan SSPModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Amiloriddiuretik hemat kaliumModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • AmiodaronantiaritmiaModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Amlodipinpenghambat kanal kalsium dihidropiridinModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Amlodipin dan atorvastatinpenghambat kanal kalsium dihidropiridinModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Amlodipin dan benazeprilpenghambat kanal kalsium dihidropiridinModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Amlodipin dan olmesartanpenghambat kanal kalsium dihidropiridinModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Amlodipin dan valsartanpenghambat kanal kalsium dihidropiridinModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Arformoterolagonis beta-adrenergikModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Artikain dan epinefrinanestetik lokalModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Asam etakrinatdiuretik loopModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Asebutololpenyekat betaModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • AtazanavirantiretroviralModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Atenololpenyekat betaModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Atenolol dan klortalidonpenyekat betaModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Azilsartanpenghambat reseptor angiotensin II (ARB)Moderat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Benazeprilpenghambat ACEModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Benazepril dan hidroklorotiazidpenghambat ACEModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Benzfetaminstimulan SSPModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Betaksololpenyekat betaModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Bisoprololpenyekat betaModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Bisoprolol dan hidroklorotiazidpenyekat betaModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Bromfeniramin, pseudoefedrin, dan dekstrometorfanantihistaminModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Budesonid dan formoterolkortikosteroidModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Bupivakain dan epinefrinanestetik lokalModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Butalbital, aspirin, dan kafeinbarbituratModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Butalbital, aspirin, kafein, dan kodeinbarbituratModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Butalbital, parasetamol, dan kafeinbarbituratModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Butalbital, parasetamol, kafein, dan kodeinbarbituratModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • DarunavirantiretroviralModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Darunavir dan kobisistatantiretroviralModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • DaunorubisinModerat

    In a clinical trial, the first two patients given high-dose cytarabine (2 g/m 2 per day) by continuous infusion with daunorubicin and bortezomib for relapsed acute myelogenous leukemia died of ARDS early in the course of therapy. (label Bortezomib, Peringatan dan perhatian)

  • Deksmetilfenidatstimulan SSPModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Dekstroamfetaminstimulan SSPModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Dietilpropionstimulan SSPModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Diltiazempenghambat kanal kalsiumModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • DobutaminsimpatomimetikModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Doksazosinpenyekat alfaModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • DroksidopasimpatomimetikModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • DronedaronantiaritmiaModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • EfedrinsimpatomimetikModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Elvitegravir, kobisistat, emtrisitabin, dan tenofovirantiretroviralModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Enalaprilpenghambat ACEModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Enalapril dan hidroklorotiazidpenghambat ACEModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Enalaprilatpenghambat ACEModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • EpinefrinsimpatomimetikModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Eplerenonantagonis aldosteronModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Ergotamin dan kafeinalkaloid ergotModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Eritromisinantibiotik makrolidaModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • EverolimusimunosupresanModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Felodipinpenghambat kanal kalsium dihidropiridinModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Fendimetrazinstimulan SSPModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • FenilefrindekongestanModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Fenoksibenzaminpenyekat alfaModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Fenterminstimulan SSPModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • FludrokortisonkortikosteroidModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Flukonazolantijamur azolModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Flutikason dan salmeterolkortikosteroidModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Formoterolagonis beta-adrenergikModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • FosamprenavirantiretroviralModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Fosaprepitantpenghambat CYP3A4Moderat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Fosinoprilpenghambat ACEModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Fosinopril dan hidroklorotiazidpenghambat ACEModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Furosemiddiuretik loopModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Guanfasinagonis alfa-adrenergikModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • HidralazinvasodilatorModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Hidroklorotiaziddiuretik tiazidModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Imatinibpenghambat CYP3A4Moderat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Indapamiddiuretik tiazidModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Ipratropium dan salbutamolantikolinergikModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Irbesartanpenghambat reseptor angiotensin II (ARB)Moderat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Irbesartan dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Moderat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • IsoniazidantibiotikModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Isoprenalinagonis beta-adrenergikModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Isosorbid dinitrat dan hidralazinnitratModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Isradipinpenghambat kanal kalsium dihidropiridinModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Itrakonazolantijamur azolModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Ivakaftorpenghambat CYP3A4Moderat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Kandesartanpenghambat reseptor angiotensin II (ARB)Moderat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Kandesartan dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Moderat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Kaptoprilpenghambat ACEModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Karvedilolpenyekat betaModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Klaritromisinantibiotik makrolidaModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Klonidinagonis alfa-adrenergikModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Klorotiaziddiuretik tiazidModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Klortalidondiuretik tiazidModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Kuinaprilpenghambat ACEModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Kuinapril dan hidroklorotiazidpenghambat ACEModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Labetalolpenyekat betaModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • LenakapavirantiretroviralModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Levosalbutamolagonis beta-adrenergikModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Lidokain dan epinefrinanestetik lokalModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Lisdeksamfetaminstimulan SSPModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Lisinoprilpenghambat ACEModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Lisinopril dan hidroklorotiazidpenghambat ACEModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Lofeksidinagonis alfa-adrenergikModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Losartanpenghambat reseptor angiotensin II (ARB)Moderat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Losartan dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Moderat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • MekamilaminantihipertensiModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Metamfetaminstimulan SSPModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • MetildopaantihipertensiModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Metilfenidatstimulan SSPModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Metolazondiuretik tiazidModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Metoprololpenyekat betaModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Metoprolol dan hidroklorotiazidpenyekat betaModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Midodrinagonis alfa-adrenergikModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Mifepristonpenghambat CYP3A4Moderat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • MinoksidilvasodilatorModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Mirabegronagonis beta-adrenergikModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Moeksiprilpenghambat ACEModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Nadololpenyekat betaModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Nebivololpenyekat betaModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • NefazodonantidepresanModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Nifedipinpenghambat kanal kalsium dihidropiridinModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Nikardipinpenghambat kanal kalsium dihidropiridinModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Nirmatrelvir dan ritonavirantivirusModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Nisoldipinpenghambat kanal kalsium dihidropiridinModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • NitroprusidvasodilatorModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • OksimetazolindekongestanModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Olmesartanpenghambat reseptor angiotensin II (ARB)Moderat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Olmesartan dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Moderat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Olmesartan, amlodipin, dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Moderat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Orfenadrin, aspirin, dan kafeinpelemas ototModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Palbosiklibpenghambat CYP3A4Moderat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • PerampanelantikonvulsanModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Perindoprilpenghambat ACEModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Pindololpenyekat betaModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Posakonazolantijamur azolModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Prazosinpenyekat alfaModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Prilokain dan epinefrinanestetik lokalModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Propranololpenyekat betaModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • PseudoefedrindekongestanModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Ramiprilpenghambat ACEModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Ranolazinobat yang memperpanjang interval QTModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Sakubitril dan valsartanpenghambat reseptor angiotensin II (ARB)Moderat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Salbutamolagonis beta-adrenergikModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Salmeterolagonis beta-adrenergikModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • SiklosporinimunosupresanModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Simetidinpenghambat H2Moderat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • SitarabinantimetabolitModerat

    In a clinical trial, the first two patients given high-dose cytarabine (2 g/m 2 per day) by continuous infusion with daunorubicin and bortezomib for relapsed acute myelogenous leukemia died of ARDS early in the course of therapy. (label Bortezomib, Peringatan dan perhatian)

  • Solriamfetolstimulan SSPModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Spironolaktonantagonis aldosteronModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Spironolakton dan hidroklorotiazidantagonis aldosteronModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Suvoreksantsedatif-hipnotikModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Telmisartanpenghambat reseptor angiotensin II (ARB)Moderat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Telmisartan dan amlodipinpenghambat reseptor angiotensin II (ARB)Moderat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Telmisartan dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Moderat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Terazosinpenyekat alfaModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Terbutalinagonis beta-adrenergikModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • TikagrelorantiplateletModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

  • Tizanidinpelemas ototModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Torasemiddiuretik loopModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Trandolaprilpenghambat ACEModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Triamterendiuretik hemat kaliumModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Triamteren dan hidroklorotiaziddiuretik hemat kaliumModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Umeklidinium dan vilanterolantikolinergikModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Valsartanpenghambat reseptor angiotensin II (ARB)Moderat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Valsartan dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Moderat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Verapamilpenghambat kanal kalsiumModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • Vibegronagonis beta-adrenergikModerat

    Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (label Bortezomib, Peringatan dan perhatian)

  • Vorikonazolantijamur azolModerat

    Strong CYP3A4 Inhibitors: Closely monitor patients with concomitant use. (label Bortezomib, Interaksi obat)

Penyebutan minor (5)

  • DoksorubisinMinor

    …platelet count of 50,000/μL was required for study eligibility ‡ Data were missing at baseline for one patient In the combination study of bortezomib with rituximab, cyclophosphamide, doxorubicin and prednisone (BR-CAP) in previously untreated mantle cell lymphoma patients, the incidence of thrombocytopenia (≥ Grade 4) was 32% vs 1% for the rituximab, cyclophosphamide,… (label Bortezomib, Peringatan dan perhatian)

  • PrednisonkortikosteroidMinor

    …50,000/μL was required for study eligibility ‡ Data were missing at baseline for one patient In the combination study of bortezomib with rituximab, cyclophosphamide, doxorubicin and prednisone (BR-CAP) in previously untreated mantle cell lymphoma patients, the incidence of thrombocytopenia (≥ Grade 4) was 32% vs 1% for the rituximab, cyclophosphamide, doxorubicin,… (label Bortezomib, Peringatan dan perhatian)

  • RituksimabimunosupresanMinor

    …(14%) 5 (71%) * A baseline platelet count of 50,000/μL was required for study eligibility ‡ Data were missing at baseline for one patient In the combination study of bortezomib with rituximab, cyclophosphamide, doxorubicin and prednisone (BR-CAP) in previously untreated mantle cell lymphoma patients, the incidence of thrombocytopenia (≥ Grade 4) was 32% vs 1% for… (label Bortezomib, Peringatan dan perhatian)

  • SiklofosfamidimunosupresanMinor

    …* A baseline platelet count of 50,000/μL was required for study eligibility ‡ Data were missing at baseline for one patient In the combination study of bortezomib with rituximab, cyclophosphamide, doxorubicin and prednisone (BR-CAP) in previously untreated mantle cell lymphoma patients, the incidence of thrombocytopenia (≥ Grade 4) was 32% vs 1% for the rituximab,… (label Bortezomib, Peringatan dan perhatian)

  • VinkristinMinor

    …baseline for one patient In the combination study of bortezomib with rituximab, cyclophosphamide, doxorubicin and prednisone (BR-CAP) in previously untreated mantle cell lymphoma patients, the incidence of thrombocytopenia (≥ Grade 4) was 32% vs 1% for the rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) arm as shown in Table 12 . (label Bortezomib, Peringatan dan perhatian)

Tidak ada interaksi bermakna yang dilaporkan (3)

  • MelfalanTanpa interaksi

    Drugs Without Clinically Significant Interactions with Bortezomib No clinically significant drug interactions have been observed when bortezomib was coadministered with dexamethasone, omeprazole, or melphalan in combination with prednisone [see Clinical Pharmacology (12.3) ] . (label Bortezomib, Interaksi obat)

  • Omeprazolpenghambat pompa protonTanpa interaksi

    Drugs Without Clinically Significant Interactions with Bortezomib No clinically significant drug interactions have been observed when bortezomib was coadministered with dexamethasone, omeprazole, or melphalan in combination with prednisone [see Clinical Pharmacology (12.3) ] . (label Bortezomib, Interaksi obat)

  • Omeprazol dan natrium bikarbonatpenghambat pompa protonTanpa interaksi

    Drugs Without Clinically Significant Interactions with Bortezomib No clinically significant drug interactions have been observed when bortezomib was coadministered with dexamethasone, omeprazole, or melphalan in combination with prednisone [see Clinical Pharmacology (12.3) ] . (label Bortezomib, Interaksi obat)

Periksa Bortezomib terhadap semua yang Anda gunakan. Tambahkan seluruh daftar Anda; setiap pasangan diperiksa sekaligus.

Buka di pemeriksa

Bukan nasihat medis. Tingkat keparahan mencerminkan kata-kata dalam label, bukan keadaan Anda. Tanda “mayor” bisa merupakan hal yang rutin di bawah pengawasan, dan tanda “minor” bisa menjadi penting pada dosis tinggi. Tanyakan kepada apoteker.