Interacciones de Imipenem y cilastatina

Imipenem y cilastatina (Primaxin), antibiótico, tiene 60 interacciones documentadas en las etiquetas de la FDA y las hojas informativas que indexamos. Graves: 32; moderadas: 27; leves: 1; casos en los que una etiqueta indica que no hay ninguna interacción significativa: 0. Cada entrada de abajo cita la frase que la respalda. Esta página del medicamento es un punto de partida, no un veredicto sobre su situación.

Interacciones según la etiqueta

Interacciones graves (32)

  • Ácido valproicoanticonvulsivoGrave

    The concomitant use of PRIMAXIN and valproic acid/divalproex sodium is generally not recommended ( 5.3 , 7.3 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • Amoxicilinaantibiótico del grupo de las penicilinasGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • Amoxicilina y ácido clavulánicoantibiótico del grupo de las penicilinasGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • Ampicilinaantibiótico del grupo de las penicilinasGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • Ampicilina y sulbactamantibiótico del grupo de las penicilinasGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • CefaclorcefalosporinaGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • CefadroxilocefalosporinaGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • CefalexinacefalosporinaGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • CefazolinacefalosporinaGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • CefdinircefalosporinaGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • CefepimacefalosporinaGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • CefiximacefalosporinaGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • CefotaximacefalosporinaGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • CefotetáncefalosporinaGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • CefoxitinacefalosporinaGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • CefpodoximacefalosporinaGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • CefprozilocefalosporinaGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • CeftarolinacefalosporinaGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • CeftazidimacefalosporinaGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • CeftriaxonacefalosporinaGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • CefuroximacefalosporinaGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • Dicloxacilinaantibiótico del grupo de las penicilinasGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • The concomitant use of PRIMAXIN and valproic acid/divalproex sodium is generally not recommended ( 5.3 , 7.3 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • GanciclovirantiviralGrave

    …Significant Drug Interactions with Ganciclovir for Injection Name of the Concomitant Drug Change in the Concentration of Ganciclovir or Concomitant Drug Clinical Comment Imipenem-cilastatin Unknown Coadministration with imipenem-cilastatin is not recommended because generalized seizures have been reported in patients who received ganciclovir and imipenem-cilastatin. (etiqueta de Ganciclovir, Interacciones medicamentosas)

  • Nafcilinaantibiótico del grupo de las penicilinasGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • Oxacilinaantibiótico del grupo de las penicilinasGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • Penicilina Gantibiótico del grupo de las penicilinasGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • Penicilina Vantibiótico del grupo de las penicilinasGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • Piperacilina y tazobactamantibiótico del grupo de las penicilinasGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • Therefore, it is not recommended that probenecid be given concomitantly with PRIMAXIN. (etiqueta de Imipenem y cilastatina, Interacciones medicamentosas)

  • Therefore, it is not recommended that probenecid be given concomitantly with PRIMAXIN. (etiqueta de Imipenem y cilastatina, Interacciones medicamentosas)

  • ValganciclovirantiviralGrave

    …Other Potentially Significant Drug Interactions with Ganciclovir Name of the Concomitant Drug Change in the Concentration of Ganciclovir or Concomitant Drug Clinical Comment Imipenem-cilastatin Unknown Coadministration with imipenem-cilastatin is not recommended because generalized seizures have been reported in patients who received ganciclovir and imipenem-cilastatin. (etiqueta de Valganciclovir, Interacciones medicamentosas)

Interacciones moderadas (27)

  • BrivaracetamanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • Cannabidiol (con receta)anticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • CarbamazepinaanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • CenobamatoanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • ClobazambenzodiazepinaModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • ClonazepambenzodiazepinaModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • EslicarbazepinaanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • EtosuximidaanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • FelbamatoanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • FenitoínaanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • FenobarbitalbarbitúricoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • Fentermina y topiramatoestimulante del SNCModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • FosfenitoínaanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • GabapentinaanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • LacosamidaanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • LamotriginaanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • LevetiracetamanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • MesuximidaanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • OxcarbazepinaanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • PerampanelanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • PregabalinaanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • PrimidonaanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • RufinamidaanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • TiagabinaanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • TopiramatoanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • VigabatrinaanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

  • ZonisamidaanticonvulsivoModerada

    If focal tremors, myoclonus, or seizures occur, patients should be evaluated neurologically, placed on anticonvulsant therapy if not already instituted, and the dosage of PRIMAXIN re-examined to determine whether it should be decreased, or the antibacterial drug discontinued ( 5.2 ). (etiqueta de Imipenem y cilastatina, Advertencias y precauciones)

Menciones leves (1)

  • Tigeciclinaantibiótico del grupo de las tetraciclinasLeve

    In cIAI studies (n=1642), 6 patients treated with TYGACIL and 2 patients treated with imipenem/cilastatin presented with intestinal perforations and developed sepsis/septic shock. (etiqueta de Tigeciclina, Advertencias y precauciones)

Compruebe Imipenem y cilastatina frente a todo lo que toma. Añada su lista completa; todos los pares se comprueban a la vez.

Abrir en el verificador

No es un consejo médico. La gravedad refleja la redacción de la etiqueta, no sus circunstancias. Una señal «grave» puede ser algo habitual bajo supervisión y una «leve» puede ser importante a dosis altas. Consulte a un farmacéutico.