पियोग्लिटाज़ोन के इंटरैक्शन

Hypoglycemia Chloroquine has been shown to cause severe hypoglycemia including loss of consciousness that could be life-threatening in patients treated with or without antidiabetic medications (see PRECAUTIONS , Drug Interactions ). (क्लोरोक्वीन लेबल, चेतावनियां)

This warning is based on the study conducted by the University Group Diabetes Program (UGDP), a long-term prospective clinical trial designed to evaluate the effectiveness of glucose-lowering drugs in preventing or delaying vascular complications in patients with non-insulin-dependent diabetes. (ग्लिपिज़ाइड और मेटफॉर्मिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))

Oral hypoglycemics Clinically significant hypoglycemia may be precipitated by the use of fluconazole with oral hypoglycemic agents; one fatality has been reported from hypoglycemia in association with combined fluconazole and glyburide use. (फ्लुकोनाज़ोल लेबल, दवाओं के इंटरैक्शन)

Antidiabetic agents Hypoglycemia including fatal outcomes have been reported. (सिप्रोफ्लॉक्सासिन लेबल, दवाओं के इंटरैक्शन)

Hypoglycemia PLAQUENIL can cause severe and potentially life-threatening hypoglycemia, in the presence or absence of antidiabetic agents [see Drug Interactions (7) ]. (हाइड्रॉक्सीक्लोरोक्वीन लेबल, चेतावनियां और सावधानियां)

Combination use with insulin and use in congestive heart failure NYHA Class I and II may increase risk. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Combination use with insulin and use in congestive heart failure NYHA Class I and II may increase risk. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Combination use with insulin and use in congestive heart failure NYHA Class I and II may increase risk. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Combination use with insulin and use in congestive heart failure NYHA Class I and II may increase risk. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Combination use with insulin and use in congestive heart failure NYHA Class I and II may increase risk. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Antidiabetic Drugs Repaglinide Saxagliptin Monitor for adverse reactions. (इट्राकोनाज़ोल लेबल, दवाओं के इंटरैक्शन)

Antidiabetic drugs: Dosage adjustment of antidiabetic may be required. (इर्बेसार्टन और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Some patients required either initiation or dose adjustments of insulin or oral hypoglycemic agents for treatment of these events. (एटाज़ानाविर लेबल, चेतावनियां और सावधानियां)

In diabetic patients dosage adjustments of insulin or oral hypoglycemic agents may be required. (एनालाप्रिल और हाइड्रोक्लोरोथायज़ाइड लेबल, सावधानियां)

Hypoglycemia: Severe hypoglycemia has been reported in patients with pre-existing diabetes who are taking medications containing thiazolidinediones (including pioglitazone) or repaglinide. (एबिराटेरोन लेबल, चेतावनियां और सावधानियां)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Antidiabetic Agents: In rare cases, diabetic patients receiving an ACE inhibitor (including benazepril) concomitantly with insulin or oral antidiabetics may develop hypoglycemia. (एम्लोडिपिन और बेनाज़ेप्रिल लेबल, दवाओं के इंटरैक्शन)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Consideration should be taken in patients being treated with antidiabetic agents. (एसिटाज़ोलामाइड लेबल, दवाओं के इंटरैक्शन)

Glyburide: In a trial of 7 healthy male volunteers, acitretin treatment potentiated the blood glucose-lowering effect of glyburide (a sulfonylurea similar to chlorpropamide) in 3 of the 7 subjects. (एसिट्रेटिन लेबल, दवाओं के इंटरैक्शन)

Oral Hypoglycemics Moderate doses of aspirin may increase the effectiveness of oral hypoglycemic drugs, leading to hypoglycemia. (एस्पिरिन और डाइपिरिडामोल लेबल, दवाओं के इंटरैक्शन)

Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed (‎ 5.2 ). (ऑक्ट्रियोटाइड लेबल, चेतावनियां और सावधानियां)

A reduction in dose of oral hypoglycemic medication (e.g., sulfonylureas) or insulin may be required in some patients [see Clinical Studies (14) ] . (ऑर्लिस्टैट लेबल, चेतावनियां और सावधानियां)

Fluoroquinolones have been associated with disturbances of blood glucose, including symptomatic hyperglycemia and hypoglycemia, usually in diabetic patients receiving concomitant treatment with an oral hypoglycemic agent (e.g., glyburide) or with insulin. (ओफ्लॉक्सासिन लेबल, चेतावनियां)

• Antidiabetic drugs: Dosage adjustment may be required. (ओल्मेसार्टन और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)

• Increased amlodipine exposure when coadministered with CYP3A inhibitors Hydrochlorothiazide ( 7.3 ): • Antidiabetic drugs: Dosage adjustment of antidiabetic may be required. (ओल्मेसार्टन, एम्लोडिपिन और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)

Insulin and oral hypoglycemics action may be enhanced. (कार्वेडिलोल लेबल, दवाओं के इंटरैक्शन)

Antidiabetics repaglinide, saxagliptin Antihelmintics and Antiprotozoals praziquantel Antimigraine Drugs ergot alkaloids, such as dihydroergotamine, ergometrine (ergonovine), ergotamine, methylergometrine (methylergonovine) eletriptan Ergot alkaloids: The potential increase in plasma concentrations of ergot alkaloids when coadministered with ketoconazole tablets… (कीटोकोनाज़ोल लेबल, दवाओं के इंटरैक्शन)

Antidiabetic drugs (oral agents and insulin) − Dosage adjustment of the antidiabetic drug may be required. (कैंडेसार्टन और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

• Strong CYP2C8 inhibitors (e.g., gemfibrozil) increase pioglitazone concentrations. (पियोग्लिटाज़ोन लेबल, दवाओं के इंटरैक्शन)

Closely monitor for adverse reactions of CYP2C9 substrates where minimal concentration changes may lead to serious adverse reactions when used concomitantly with XELODA (e.g., anticoagulants, antidiabetic drugs). (कैपेसिटाबिन लेबल, दवाओं के इंटरैक्शन)

…TG levels occurred when colesevelam hydrochloride was used as monotherapy (median increase 9.7% compared to placebo) and when colesevelam hydrochloride was used in combination with pioglitazone (median increase 11% compared to placebo in combination with pioglitazone), sulfonylureas (median increase 18% compared to placebo in combination with sulfonylureas), and… (कोलेसेवेलम लेबल, चेतावनियां और सावधानियां)

With certain hypoglycemic drugs such as nateglinide, pioglitazone, repaglinide and rosiglitazone, inhibition of CYP3A enzyme by clarithromycin may be involved and could cause hypoglycemia when used concomitantly. (क्लैरिथ्रोमाइसिन लेबल, चेतावनियां और सावधानियां)

Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (क्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)

• Hypoglycemia: When used with insulin or an insulin secretagogue, a lower dose of the insulin or insulin secretagogue may be needed to reduce the risk of hypoglycemia. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

• Hypoglycemia: When used with insulin or an insulin secretagogue, a lower dose of the insulin or insulin secretagogue may be needed to reduce the risk of hypoglycemia. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

• Hypoglycemia: When used with insulin or an insulin secretagogue, a lower dose of the insulin or insulin secretagogue may be needed to reduce the risk of hypoglycemia. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

• Hypoglycemia: When used with insulin or an insulin secretagogue, a lower dose of the insulin or insulin secretagogue may be needed to reduce the risk of hypoglycemia. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

• Strong CYP2C8 inhibitors (e.g., gemfibrozil) increase pioglitazone concentrations. (पियोग्लिटाज़ोन लेबल, दवाओं के इंटरैक्शन)

Masking of Hypoglycemic Symptoms in Patients with Diabetes Mellitus Beta-adrenergic blocking agents should be administered with caution in patients subject to spontaneous hypoglycemia or to diabetic patients (especially those with labile diabetes) who are receiving insulin or oral hypoglycemic agents. (टिमोलोल लेबल, चेतावनियां और सावधानियां)

Combination use with insulin and use in congestive heart failure NYHA Class I and II may increase risk. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

This may result in the need for an increase in the dose of, or initiation of, insulin and/or oral hypoglycemic agent therapy. (टेम्सिरोलिमस लेबल, चेतावनियां और सावधानियां)

In patients taking AUBAGIO, exposure of drugs metabolized by CYP2C8 (e.g., paclitaxel, pioglitazone, repaglinide, rosiglitazone) may be increased. (टेरिफ्लुनोमाइड लेबल, दवाओं के इंटरैक्शन)

Antidiabetic drugs: Dosage adjustment may be required ( 7.6 ) (टेल्मिसार्टन और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)

• Topiramate may decrease pioglitazone concentrations. (पियोग्लिटाज़ोन लेबल, दवाओं के इंटरैक्शन)

• Strong CYP2C8 inhibitors (e.g., gemfibrozil) increase pioglitazone concentrations. (पियोग्लिटाज़ोन लेबल, दवाओं के इंटरैक्शन)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (ट्रायमटेरिन लेबल, दवाओं के इंटरैक्शन)

Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (ट्रायमटेरिन और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)

Antidiabetics: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (ट्रायमसिनोलोन लेबल, दवाओं के इंटरैक्शन)

(See PRECAUTIONS . ) Antidiabetic Agents Concomitant use of ACE inhibitors and antidiabetic medicines (insulin or oral hypoglycemic agents) may cause an increased blood glucose lowering effect with greater risk of hypoglycemia. (ट्रैंडोलाप्रिल लेबल, दवाओं के इंटरैक्शन)

Hypoglycemia in Diabetic Patients Some MAOIs have contributed to hypoglycemic episodes in diabetic patients receiving insulin or other blood-glucose-lowering agents. (ट्रैनिलसाइप्रोमिन लेबल, चेतावनियां और सावधानियां)

Initiation or dose adjustments of insulin or oral hypoglycemic agents may be required. (डारुनाविर लेबल, चेतावनियां और सावधानियां)

Some patients required either initiation or dose adjustments of insulin or oral hypoglycemic agents for treatment of these events. (डारुनाविर और कोबिसिस्टैट लेबल, चेतावनियां और सावधानियां)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Hyperglycemia Corticosteroids can increase blood glucose, worsen pre-existing diabetes, and predispose those on long-term therapy to diabetes mellitus, and may reduce the effect of the antidiabetic drugs. (डेक्सामेथासोन लेबल, चेतावनियां और सावधानियां)

• Strong CYP2C8 inhibitors (e.g., gemfibrozil) increase pioglitazone concentrations. (पियोग्लिटाज़ोन लेबल, दवाओं के इंटरैक्शन)

Caution should be exercised when used with antidiabetic drugs. (डैनाज़ोल लेबल, दवाओं के इंटरैक्शन)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Masking of Hypoglycemic Symptoms in Patients with Diabetes Mellitus Beta-adrenergic blocking agents should be administered with caution in patients subject to spontaneous hypoglycemia or to diabetic patients (especially those with labile diabetes) who are receiving insulin or oral hypoglycemic agents. (डोरज़ोलामाइड और टिमोलोल लेबल, चेतावनियां और सावधानियां)

Beta-blockade also reduces the release of insulin in response to hyperglycemia; therefore, it may be necessary to adjust the dose of antidiabetic drugs. (नाडोलोल लेबल, चेतावनियां)

Use of Antidiabetic Medications: Weight loss may cause hypoglycemia. (नाल्ट्रेक्सोन और ब्यूप्रोपियॉन लेबल, चेतावनियां और सावधानियां)

• Strong CYP2C8 inhibitors (e.g., gemfibrozil) increase pioglitazone concentrations. (पियोग्लिटाज़ोन लेबल, दवाओं के इंटरैक्शन)

• Hypoglycemia: When used with insulin or an insulin secretagogue, a lower dose of the insulin or insulin secretagogue may be needed to reduce the risk of hypoglycemia. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Beta-blockade also reduces the release of insulin in response to hyperglycemia; therefore, it may be necessary to adjust the dose of antidiabetic drugs. (पिंडोलोल लेबल, चेतावनियां)

• Hypoglycemia: When used with insulin or an insulin secretagogue, a lower dose of the insulin or insulin secretagogue may be needed to reduce the risk of hypoglycemia. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

• Strong CYP2C8 inhibitors (e.g., gemfibrozil) increase pioglitazone concentrations. (पियोग्लिटाज़ोन लेबल, दवाओं के इंटरैक्शन)

Monitor patients for the development of edema when co-administering LYRICA CR and thiazolidinedione antidiabetic agents. (प्रीगैबलिन लेबल, चेतावनियां और सावधानियां)

Antidiabetic agents: May increase blood glucose concentrations. (प्रेडनिसोन लेबल, दवाओं के इंटरैक्शन)

Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (प्रेडनिसोलोन लेबल, दवाओं के इंटरैक्शन)

• A reduction in dose of insulin or oral hypoglycemic medication may be required in some patients. (फेंटरमिन लेबल, चेतावनियां और सावधानियां)

• Topiramate may decrease pioglitazone concentrations. (पियोग्लिटाज़ोन लेबल, दवाओं के इंटरैक्शन)

Some patients required either initiation or dose adjustments of insulin or oral hypoglycemic agents for treatment of these events. (फोसएम्प्रेनाविर लेबल, चेतावनियां और सावधानियां)

As is true with many other types of medication when taken concurrently by patients with diabetes, insulin and/or oral hypoglycemic, dosage may need to be adjusted when therapy with PROZAC is instituted or discontinued. (फ्लुओक्सेटिन लेबल, चेतावनियां और सावधानियां)

Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (फ्लुड्रोकॉर्टिसोन लेबल, दवाओं के इंटरैक्शन)

However, patients subject to spontaneous hypoglycemia, or diabetic patients receiving insulin or oral hypoglycemic agents, should be cautioned about these possibilities and bisoprolol fumarate should be used with caution. (बिसोप्रोलोल लेबल, चेतावनियां)

Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (बिसोप्रोलोल और हाइड्रोक्लोरोथायज़ाइड लेबल, सावधानियां)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (बेक्सारोटीन लेबल, चेतावनियां और सावधानियां)

Antidiabetics: Increased risk of hypoglycemia ( 7.2 ) (बेनाज़ेप्रिल लेबल, दवाओं के इंटरैक्शन)

Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (बेनाज़ेप्रिल और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)

Oral antidiabetic agents and insulin, causing hypoglycemia by contributing an additive effect, if dosage of Butalbital, Aspirin, and Caffeine Capsules exceeds maximum recommended daily dosage. (ब्यूटाल्बिटल, एस्पिरिन और कैफीन लेबल, दवाओं के इंटरैक्शन)

Evaluate the blood pressure and renal function of patients Examples: Metoprolol, propranolol Hypoglycemic Agents Clinical Impact: Aspirin may increase the serum glucose-lowering action of insulin and sulfonylureas leading to hypoglycemia. (ब्यूटाल्बिटल, एस्पिरिन, कैफीन और कोडीन लेबल, दवाओं के इंटरैक्शन)

Masking of Hypoglycemic Symptoms in Patients with Diabetes Mellitus Beta-adrenergic blocking agents should be administered with caution in patients subject to spontaneous hypoglycemia or to diabetic patients (especially those with labile diabetes) who are receiving insulin or oral hypoglycemic agents. (ब्रिमोनिडिन और टिमोलोल लेबल, चेतावनियां और सावधानियां)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (मिथाइलप्रेडनिसोलोन लेबल, दवाओं के इंटरैक्शन)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Antidiabetic drugs: Dosage adjustment may be required. (मेटोप्रोलोल और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)

Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (मेटोलाज़ोन लेबल, दवाओं के इंटरैक्शन)

Antidiabetic agents Carefully monitor blood glucose. (मॉक्सीफ्लॉक्सासिन लेबल, दवाओं के इंटरैक्शन)

Some patients required either initiation or dose adjustments of insulin or oral hypoglycemic agents for treatment of these events. (रिटोनाविर लेबल, चेतावनियां और सावधानियां)

…Diazepam Beta-Blockers Propranolol Calcium Channel Blockers Diltiazem, nifedipine, verapamil Cardiac Glycoside Preparations Digoxin Corticosteroids Prednisone Fibrates Clofibrate Oral Hypoglycemics Sulfonylureas (e.g., glyburide, glipizide) Hormonal Contraceptives/Progestins Ethinyl estradiol, levonorgestrel Immunosuppressants Cyclosporine, tacrolimus Methylxanthines… (रिफापेंटिन लेबल, दवाओं के इंटरैक्शन)

• CYP2C8 inducers (e.g., rifampin) may decrease pioglitazone concentrations. (पियोग्लिटाज़ोन लेबल, दवाओं के इंटरैक्शन)

Combination use with insulin and use in congestive heart failure NYHA Class I and II may increase risk. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

• Hypoglycemia: When used with insulin or an insulin secretagogue, a lower dose of the insulin or insulin secretagogue may be needed to reduce the risk of hypoglycemia. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

• Hypoglycemia: Postmarketing cases of symptomatic hypoglycemia have been reported in patients with diabetes mellitus receiving insulin or oral hypoglycemic agents. (लिनेज़ोलिड लेबल, चेतावनियां और सावधानियां)

• Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (लियोथायरोनिन लेबल, चेतावनियां और सावधानियां)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Antidiabetics Concomitant administration of Zestril and antidiabetic medicines (insulins, oral hypoglycemic agents) may cause an increased blood-glucose-lowering effect with risk of hypoglycemia. (लिसिनोप्रिल लेबल, दवाओं के इंटरैक्शन)

Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (लिसिनोप्रिल और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)

In patients taking ARAVA, exposure of drugs metabolized by CYP2C8 (e.g., paclitaxel, pioglitazone, repaglinide, rosiglitazone) may be increased. (लेफ्लुनोमाइड लेबल, दवाओं के इंटरैक्शन)

Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (लेवोथायरोक्सिन लेबल, चेतावनियां और सावधानियां)

Insulin or Oral Hypoglycemics — Initiating thyroid replacement therapy may cause increases in insulin or oral hypoglycemic requirements. (लेवोथायरोक्सिन और लियोथायरोनिन लेबल, दवाओं के इंटरैक्शन)

Blood Glucose Disturbances Fluoroquinolones, including Levofloxacin in 5% Dextrose Injection, have been associated with disturbances of blood glucose, including symptomatic hyperglycemia and hypoglycemia, usually in diabetic patients receiving concomitant treatment with an oral hypoglycemic agent (e.g., glyburide) or with insulin. (लेवोफ्लॉक्सासिन लेबल, चेतावनियां और सावधानियां)

Hyperglycemia and Hypoglycemia : Glucose monitoring is recommended and antidiabetic treatment adjusted accordingly. (लैनरियोटाइड लेबल, चेतावनियां और सावधानियां)

Some patients required either initiation or dose adjustments of insulin or oral hypoglycemic agents for treatment of these events. (लोपिनाविर और रिटोनाविर लेबल, चेतावनियां और सावधानियां)

Antidiabetic drugs: dosage adjustment of antidiabetic may be required. (लोसार्टन और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)

…ritonavir, saquinavir, telithromycin, tipranavir, voriconazole, zileuton armodafinil, amprenavir, aprepitant, bosentan, carbamazepine, efavirenz, etravirine, modafinil, nafcillin, phenytoin, pioglitazone, prednisone, rifampin, rufinamide 7.3 Drugs that Increase Bleeding Risk Examples of drugs known to increase the risk of bleeding are presented in Table 3 . (वारफेरिन लेबल, दवाओं के इंटरैक्शन)

Hydrochlorothiazide: When administered concurrently, the following drugs may interact with thiazide diuretics: Antidiabetic Drugs (oral agents and insulin) - Dosage adjustment of the antidiabetic drug may be required. (वाल्सार्टन और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)

Sulfonylurea Oral Hypoglycemics (CYP2C9 Inhibition) Not Studied In Vivo or In Vitro , but Drug Plasma Exposure Likely to be Increased Frequent monitoring of blood glucose and for signs and symptoms of hypoglycemia. (वोरिकोनाज़ोल लेबल, दवाओं के इंटरैक्शन)

• Strong CYP2C8 inhibitors (e.g., gemfibrozil) increase pioglitazone concentrations. (पियोग्लिटाज़ोन लेबल, दवाओं के इंटरैक्शन)

Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (साल्सालेट लेबल, दवाओं के इंटरैक्शन)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

• Hypoglycemia : Check blood glucose levels regularly and assess if antidiabetic drug dose modifications are required. (सुनिटिनिब लेबल, चेतावनियां और सावधानियां)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Congestive Heart Failure ACTOS, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when ACTOS is used in combination with insulin. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)

Insulin and Oral Antidiabetics Hyperglycemia may occur, and the dosage of insulin or antidiabetic drugs may require adjustment. (सोटालोल लेबल, दवाओं के इंटरैक्शन)

The doses of antidiabetic agents may require adjustment when HUMATROPE is initiated. (सोमाट्रोपिन लेबल, चेतावनियां और सावधानियां)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (स्पिरोनोलैक्टोन और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)

Antidiabetic Agents Clinical Impact: Corticosteroids in supraphysiologic doses may increase blood glucose concentrations. (हाइड्रोकॉर्टिसोन लेबल, दवाओं के इंटरैक्शन)

Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)

In some cases, hyperglycemia has resolved when the atypical antipsychotic was discontinued; however, some patients required continuation of antidiabetic treatment despite discontinuation of the suspect drug. (क्लोज़ापिन लेबल, चेतावनियां और सावधानियां)

In some cases, hyperglycemia has resolved when the atypical antipsychotic was discontinued; however, some patients required continuation of antidiabetic treatment despite discontinuation of the suspect drug. (ज़िप्रासिडोन लेबल, चेतावनियां और सावधानियां)

Drug Interactions with Amlodipine In clinical trials, amlodipine has been safely administered with thiazide diuretics, beta-blockers, angiotensin-converting enzyme inhibitors, long-acting nitrates, sublingual nitroglycerin, digoxin, warfarin, non-steroidal anti-inflammatory drugs, antibiotics, and oral hypoglycemic drugs. (टेल्मिसार्टन और एम्लोडिपिन लेबल, दवाओं के इंटरैक्शन)

Hypoglycemic Agents: In adult diabetic patients under treatment with either sulfonylureas or insulin there is no change in the clinical effects of either TOLECTIN or the hypoglycemic agents. (टोल्मेटिन लेबल, दवाओं के इंटरैक्शन)

Antidiabetic drug requirements (i.e., insulin) may be altered. (डाइएथिलप्रोपियॉन लेबल, दवाओं के इंटरैक्शन)

Glucose Lowering Drugs Pioglitazone: Co-administration of pioglitazone for 7 days with 30 mg nifedipine ER administered orally q.d. for 4 days to male and female volunteers resulted in least square mean (90% CI) values for unchanged nifedipine of 0.83 (0.73-0.95) for C max and 0.88 (0.80-0.96) for AUC relative to nifedipine monotherapy. (निफेडिपिन लेबल, सावधानियां)

Moderate and weak CYP3A4 inducers include, for example: amprenavir, aprepitant, armodafinil, bosentan, efavirnenz, etravirine, Echinacea, modafinil, nafcillin, pioglitazone, prednisone, rufinamide, and vemurafenib. (निमोडिपिन लेबल, दवाओं के इंटरैक्शन)

Insulin and Oral Hypoglycemic Medications Requirements may be altered. (फेनडाइमेट्राज़िन लेबल, दवाओं के इंटरैक्शन)

Additional predisposing conditions include diabetes mellitus treated with oral hypoglycemic drugs or insulin, use of anorectic drugs, excessive use of alcohol, use of benzodiazepines, sedatives/hypnotics, or opiates. (ब्यूप्रोपियॉन लेबल, चेतावनियां और सावधानियां)

Although the systemic absorption of miconazole following ORAVIG administration is minimal and plasma concentrations of miconazole are substantially lower than when given intravenously, the potential for interaction with drugs metabolized through CYP2C9 and CYP3A4 such as oral hypoglycemics, phenytoin, or ergot alkaloids cannot be ruled out. (माइकोनाज़ोल लेबल, दवाओं के इंटरैक्शन)

Moexipril hydrochloride has been used in clinical trials concomitantly with calcium-channel-blocking agents, diuretics, H 2 blockers, digoxin, oral hypoglycemic agents, and cholesterol-lowering agents. (मोएक्सिप्रिल लेबल, दवाओं के इंटरैक्शन)

Oral Hypoglycemic Agents In pharmacokinetic studies of lovastatin in hypercholesterolemic non-insulin dependent diabetic patients, there was no drug interaction with glipizide or with chlorpropamide (see CLINICAL PHARMACOLOGY , Clinical Studies in Adults ). (लोवास्टेटिन लेबल, दवाओं के इंटरैक्शन)

Potentiation of the action of sulfonylurea hypoglycemic agents, thiazide diuretics and uricosuric agents may also be noted. (सल्फाडायज़िन लेबल, दवाओं के इंटरैक्शन)

Oral hypoglycemic agents Although sulindac and its sulfide metabolite are highly bound to protein, studies in which sulindac was given at a dose of 400 mg daily, have shown no clinically significant interaction with oral hypoglycemic agents. (सुलिंडैक लेबल, दवाओं के इंटरैक्शन)