टिर्ज़ेपाटाइड के इंटरैक्शन
हम जिन FDA लेबल और फैक्ट शीट को इंडेक्स करते हैं, उनमें टिर्ज़ेपाटाइड (Mounjaro, Zepbound; GLP-1 रिसेप्टर एगोनिस्ट) के 184 इंटरैक्शन दर्ज हैं: 17 गंभीर, 143 मध्यम, 21 मामूली, और 3 ऐसे जिनमें लेबल बताता है कि कोई महत्वपूर्ण इंटरैक्शन नहीं है। नीचे की हर प्रविष्टि उस वाक्य को उद्धृत करती है जिस पर वह आधारित है। दवा का यह पेज एक शुरुआती बिंदु है, आपकी स्थिति के लिए कोई फ़ैसला नहीं।
लेबल से लिए गए इंटरैक्शन
गंभीर इंटरैक्शन (17)
To avoid medication errors between LEVEMIR and other insulins, instruct patients to always check the insulin label before each injection. (इंसुलिन डेटेमिर लेबल, चेतावनियां और सावधानियां)
To avoid medication errors between LYUMJEV and other insulins, instruct patients to always check the insulin label before each injection. (इंसुलिन लिस्प्रो लेबल, चेतावनियां और सावधानियां)
Hypoglycemia Chloroquine has been shown to cause severe hypoglycemia including loss of consciousness that could be life-threatening in patients treated with or without antidiabetic medications (see PRECAUTIONS , Drug Interactions ). (क्लोरोक्वीन लेबल, चेतावनियां)
Diabetic ketoacidosis should be treated with insulin. (ग्लिपिज़ाइड और मेटफॉर्मिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
These conditions should be treated with insulin. (ग्लिबेनक्लामाइड लेबल, निषेध (कॉन्ट्राइंडिकेशन))
WARNING: RISK OF THYROID C-CELL TUMORS In rats, tirzepatide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. (टिर्ज़ेपाटाइड लेबल, बॉक्स्ड चेतावनी)
Diabetic ketoacidosis should be treated with insulin [see Warnings and Precautions (5.1) and Warnings and Precautions (5.2) ] . (डैपाग्लिफ्लोज़िन और मेटफॉर्मिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
- प्रोटामिनगंभीर
Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (प्रोटामिन लेबल, बॉक्स्ड चेतावनी)
WARNING: RISK OF THYROID C-CELL TUMORS In rats, tirzepatide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. (टिर्ज़ेपाटाइड लेबल, बॉक्स्ड चेतावनी)
Oral hypoglycemics Clinically significant hypoglycemia may be precipitated by the use of fluconazole with oral hypoglycemic agents; one fatality has been reported from hypoglycemia in association with combined fluconazole and glyburide use. (फ्लुकोनाज़ोल लेबल, दवाओं के इंटरैक्शन)
WARNING: RISK OF THYROID C-CELL TUMORS In rats, tirzepatide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. (टिर्ज़ेपाटाइड लेबल, बॉक्स्ड चेतावनी)
WARNING: RISK OF THYROID C-CELL TUMORS In rats, tirzepatide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. (टिर्ज़ेपाटाइड लेबल, बॉक्स्ड चेतावनी)
WARNING: RISK OF THYROID C-CELL TUMORS In rats, tirzepatide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. (टिर्ज़ेपाटाइड लेबल, बॉक्स्ड चेतावनी)
WARNING: RISK OF THYROID C-CELL TUMORS In rats, tirzepatide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. (टिर्ज़ेपाटाइड लेबल, बॉक्स्ड चेतावनी)
Antidiabetic agents Hypoglycemia including fatal outcomes have been reported. (सिप्रोफ्लॉक्सासिन लेबल, दवाओं के इंटरैक्शन)
Diabetic ketoacidosis should be treated with insulin. (सैक्साग्लिप्टिन और मेटफॉर्मिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
Hypoglycemia PLAQUENIL can cause severe and potentially life-threatening hypoglycemia, in the presence or absence of antidiabetic agents [see Drug Interactions (7) ]. (हाइड्रॉक्सीक्लोरोक्वीन लेबल, चेतावनियां और सावधानियां)
मध्यम इंटरैक्शन (143)
Increase frequency of glucose monitoring with changes to: insulin dosage, concomitantly administered glucose lowering medications, meal pattern, physical activity; and in patients with renal or hepatic impairments and hypoglycemia unawareness ( 5. (इंसुलिन एस्पार्ट लेबल, चेतावनियां और सावधानियां)
For patients with type 2 diabetes, dosage adjustments of concomitant oral and antidiabetic products may be needed. (इंसुलिन ग्लार्जिन लेबल, चेतावनियां और सावधानियां)
The risk of hypoglycemia after an injection is related to the duration of action of the insulin [see Clinical Pharmacology ( 12.2 )] and, in general, is highest when the glucose lowering effect of the insulin is maximal. (इंसुलिन डेग्लुडेक लेबल, चेतावनियां और सावधानियां)
Antidiabetic Drugs Repaglinide Saxagliptin Monitor for adverse reactions. (इट्राकोनाज़ोल लेबल, दवाओं के इंटरैक्शन)
Antidiabetic drugs: Dosage adjustment of antidiabetic may be required. (इर्बेसार्टन और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)
When such drugs are withdrawn from patients receiving acarbose tablets in combination with sulfonylureas or insulin, patients should be observed closely for any evidence of hypoglycemia. (एकार्बोज़ लेबल, दवाओं के इंटरैक्शन)
• Hypoglycemia with Concomitant Use of Insulin Secretagogues or Insulin: Patients taking an insulin secretagogue or insulin may have an increased risk of hypoglycemia, including severe hypoglycemia. (एक्सेनाटाइड लेबल, चेतावनियां और सावधानियां)
At recommended doses atenolol does not potentiate insulin-induced hypoglycemia and, unlike nonselective beta- blockers, does not delay recovery of blood glucose to normal levels. (एटेनोलोल और क्लोरथैलिडोन लेबल, चेतावनियां)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Anti-diabetic drugs (oral agents and insulin) Dosage adjustment of the anti-diabetic drug may be required. (एनालाप्रिल और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)
Monitor blood glucose in patients with diabetes and assess if antidiabetic agent dose modifications are required. (एबिराटेरोन लेबल, चेतावनियां और सावधानियां)
Hypoglycemia: Adult patients taking an insulin secretagogue or insulin may have an increased risk of hypoglycemia. (एम्पाग्लिफ्लोज़िन लेबल, चेतावनियां और सावधानियां)
Hypoglycemia: Adult patients taking an insulin secretagogue or insulin may have an increased risk of hypoglycemia. (एम्पाग्लिफ्लोज़िन और मेटफॉर्मिन लेबल, चेतावनियां और सावधानियां)
Antidiabetic Agents: In rare cases, diabetic patients receiving an ACE inhibitor (including benazepril) concomitantly with insulin or oral antidiabetics may develop hypoglycemia. (एम्लोडिपिन और बेनाज़ेप्रिल लेबल, दवाओं के इंटरैक्शन)
Hypoglycemia: Consider lowering the dosage of insulin secretagogue or insulin to reduce the risk of hypoglycemia when initiating Alogliptin tablets. (एलोग्लिप्टिन लेबल, चेतावनियां और सावधानियां)
Hypoglycemia: Consider lowering the dosage of insulin secretagogue or insulin to reduce the risk of hypoglycemia when initiating Alogliptin and metformin HCl tablets. (एलोग्लिप्टिन और मेटफॉर्मिन लेबल, चेतावनियां और सावधानियां)
The effects of increases in the concentration of the progestational component norgestimate are not fully known and can include increased risk of insulin resistance, dyslipidemia, acne, and venous thrombosis. (एल्विटेग्राविर, कोबिसिस्टैट, एमट्रिसिटाबिन और टेनोफोविर लेबल, दवाओं के इंटरैक्शन)
Consideration should be taken in patients being treated with antidiabetic agents. (एसिटाज़ोलामाइड लेबल, दवाओं के इंटरैक्शन)
Glyburide: In a trial of 7 healthy male volunteers, acitretin treatment potentiated the blood glucose-lowering effect of glyburide (a sulfonylurea similar to chlorpropamide) in 3 of the 7 subjects. (एसिट्रेटिन लेबल, दवाओं के इंटरैक्शन)
Diabetes and Hypoglycemia β-blockers may potentiate insulin-induced hypoglycemia and mask some of its manifestations such as tachycardia; however, dizziness and sweating are usually not significantly affected. (एसिब्यूटोलोल लेबल, चेतावनियां)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Oral Hypoglycemics Moderate doses of aspirin may increase the effectiveness of oral hypoglycemic drugs, leading to hypoglycemia. (एस्पिरिन और डाइपिरिडामोल लेबल, दवाओं के इंटरैक्शन)
- ऑक्ट्रियोटाइडमध्यम
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (ऑक्ट्रियोटाइड लेबल, चेतावनियां और सावधानियां)
- ऑर्लिस्टैटमध्यम
A reduction in dose of oral hypoglycemic medication (e.g., sulfonylureas) or insulin may be required in some patients [see Clinical Studies (14) ] . (ऑर्लिस्टैट लेबल, चेतावनियां और सावधानियां)
Fluoroquinolones have been associated with disturbances of blood glucose, including symptomatic hyperglycemia and hypoglycemia, usually in diabetic patients receiving concomitant treatment with an oral hypoglycemic agent (e.g., glyburide) or with insulin. (ओफ्लॉक्सासिन लेबल, चेतावनियां)
• Antidiabetic drugs: Dosage adjustment may be required. (ओल्मेसार्टन और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)
• Increased amlodipine exposure when coadministered with CYP3A inhibitors Hydrochlorothiazide ( 7.3 ): • Antidiabetic drugs: Dosage adjustment of antidiabetic may be required. (ओल्मेसार्टन, एम्लोडिपिन और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Insulin and oral hypoglycemics action may be enhanced. (कार्वेडिलोल लेबल, दवाओं के इंटरैक्शन)
Antidiabetics repaglinide, saxagliptin Antihelmintics and Antiprotozoals praziquantel Antimigraine Drugs ergot alkaloids, such as dihydroergotamine, ergometrine (ergonovine), ergotamine, methylergometrine (methylergonovine) eletriptan Ergot alkaloids: The potential increase in plasma concentrations of ergot alkaloids when coadministered with ketoconazole tablets… (कीटोकोनाज़ोल लेबल, दवाओं के इंटरैक्शन)
Antidiabetic drugs (oral agents and insulin) − Dosage adjustment of the antidiabetic drug may be required. (कैंडेसार्टन और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)
• Hypoglycemia with Concomitant Use with Insulin or Insulin Secretagogues : Consider a lower dose of insulin or the insulin secretagogue to reduce the risk of hypoglycemia when used in combination with INVOKANA ( 5.5 ). (कैनाग्लिफ्लोज़िन लेबल, चेतावनियां और सावधानियां)
Closely monitor for adverse reactions of CYP2C9 substrates where minimal concentration changes may lead to serious adverse reactions when used concomitantly with XELODA (e.g., anticoagulants, antidiabetic drugs). (कैपेसिटाबिन लेबल, दवाओं के इंटरैक्शन)
During the 8-week trial, serum insulin levels increased by 12 pmol/L in the VRAYLAR 1 mg to 2 mg per day group, 20 pmol/L in the VRAYLAR 2 mg to 4.5 mg per day group, and 8.5 pmol/L in the placebo group. (कैरिप्राज़िन लेबल, चेतावनियां और सावधानियां)
…placebo) and when colesevelam hydrochloride was used in combination with pioglitazone (median increase 11% compared to placebo in combination with pioglitazone), sulfonylureas (median increase 18% compared to placebo in combination with sulfonylureas), and insulin (median increase 22% compared to placebo in combination with insulin) [see Adverse Reactions (6.1) ]. (कोलेसेवेलम लेबल, चेतावनियां और सावधानियां)
Oral Hypoglycemic Agents/Insulin: The concomitant use of clarithromycin tablets and oral hypoglycemic agents and/or insulin can result in significant hypoglycemia. (क्लैरिथ्रोमाइसिन लेबल, चेतावनियां और सावधानियां)
Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (क्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)
Hypoglycemia Quinine stimulates release of insulin from the pancreas, and patients, especially pregnant women, may experience clinically significant hypoglycemia. (क्विनीन लेबल, चेतावनियां और सावधानियां)
Hypoglycemia: Concomitant use with insulin or an insulin secretagogue may increase the risk of hypoglycemia, including severe hypoglycemia. (टिर्ज़ेपाटाइड लेबल, चेतावनियां और सावधानियां)
Hypoglycemia: Concomitant use with insulin or an insulin secretagogue may increase the risk of hypoglycemia, including severe hypoglycemia. (टिर्ज़ेपाटाइड लेबल, चेतावनियां और सावधानियां)
Hypoglycemia: Concomitant use with insulin or an insulin secretagogue may increase the risk of hypoglycemia, including severe hypoglycemia. (टिर्ज़ेपाटाइड लेबल, चेतावनियां और सावधानियां)
- ग्लूकागॉनमध्यम
Hypoglycemia in Patients with Insulinoma: In patients with insulinoma, administration may produce an initial increase in blood glucose; however, glucagon may stimulate exaggerated insulin release from an insulinoma and cause hypoglycemia. (ग्लूकागॉन लेबल, चेतावनियां और सावधानियां)
Masking of Hypoglycemic Symptoms in Patients with Diabetes Mellitus Beta-adrenergic blocking agents should be administered with caution in patients subject to spontaneous hypoglycemia or to diabetic patients (especially those with labile diabetes) who are receiving insulin or oral hypoglycemic agents. (टिमोलोल लेबल, चेतावनियां और सावधानियां)
- टेम्सिरोलिमसमध्यम
This may result in the need for an increase in the dose of, or initiation of, insulin and/or oral hypoglycemic agent therapy. (टेम्सिरोलिमस लेबल, चेतावनियां और सावधानियां)
Antidiabetic drugs: Dosage adjustment may be required ( 7.6 ) (टेल्मिसार्टन और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)
Insulin: In patients with diabetes, concomitant use with TLANDO may decrease blood glucose and insulin requirements ( 7.1) . (टेस्टोस्टेरोन लेबल, दवाओं के इंटरैक्शन)
Infusion of glucose and insulin has also been used to treat hyperkalemia. (ट्रायमटेरिन लेबल, चेतावनियां और सावधानियां)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (ट्रायमटेरिन और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)
Antidiabetics: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (ट्रायमसिनोलोन लेबल, दवाओं के इंटरैक्शन)
(See PRECAUTIONS . ) Antidiabetic Agents Concomitant use of ACE inhibitors and antidiabetic medicines (insulin or oral hypoglycemic agents) may cause an increased blood glucose lowering effect with greater risk of hypoglycemia. (ट्रैंडोलाप्रिल लेबल, दवाओं के इंटरैक्शन)
Hypoglycemia in Diabetic Patients Some MAOIs have contributed to hypoglycemic episodes in diabetic patients receiving insulin or other blood-glucose-lowering agents. (ट्रैनिलसाइप्रोमिन लेबल, चेतावनियां और सावधानियां)
Hypoglycemia: Concomitant use with an insulin secretagogue or insulin may increase the risk of hypoglycemia, including severe hypoglycemia. (डुलाग्लूटाइड लेबल, चेतावनियां और सावधानियां)
Hyperglycemia Corticosteroids can increase blood glucose, worsen pre-existing diabetes, and predispose those on long-term therapy to diabetes mellitus, and may reduce the effect of the antidiabetic drugs. (डेक्सामेथासोन लेबल, चेतावनियां और सावधानियां)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Caution should be exercised when used with antidiabetic drugs. (डैनाज़ोल लेबल, दवाओं के इंटरैक्शन)
• Hypoglycemia: Consider a lower dose of insulin or the insulin secretagogue to reduce the risk of hypoglycemia when used in combination with DAPAGLIFLOZIN TABLETS. (डैपाग्लिफ्लोज़िन लेबल, चेतावनियां और सावधानियां)
Masking of Hypoglycemic Symptoms in Patients with Diabetes Mellitus Beta-adrenergic blocking agents should be administered with caution in patients subject to spontaneous hypoglycemia or to diabetic patients (especially those with labile diabetes) who are receiving insulin or oral hypoglycemic agents. (डोरज़ोलामाइड और टिमोलोल लेबल, चेतावनियां और सावधानियां)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Beta-blockade also reduces the release of insulin in response to hyperglycemia; therefore, it may be necessary to adjust the dose of antidiabetic drugs. (नाडोलोल लेबल, चेतावनियां)
Use of Antidiabetic Medications: Weight loss may cause hypoglycemia. (नाल्ट्रेक्सोन और ब्यूप्रोपियॉन लेबल, चेतावनियां और सावधानियां)
Hypoglycemia: Concomitant use with insulin or an insulin secretagogue may increase the risk of hypoglycemia, including severe hypoglycemia. (टिर्ज़ेपाटाइड लेबल, चेतावनियां और सावधानियां)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Beta-blockade also reduces the release of insulin in response to hyperglycemia; therefore, it may be necessary to adjust the dose of antidiabetic drugs. (पिंडोलोल लेबल, चेतावनियां)
Combination use with insulin and use in congestive heart failure NYHA Class I and II may increase risk. (पियोग्लिटाज़ोन लेबल, चेतावनियां और सावधानियां)
Hypoglycemia: Concomitant use with insulin or an insulin secretagogue may increase the risk of hypoglycemia, including severe hypoglycemia. (टिर्ज़ेपाटाइड लेबल, चेतावनियां और सावधानियां)
Combination use with insulin and use in congestive heart failure NYHA Class I and II may increase risk. (पियोग्लिटाज़ोन और मेटफॉर्मिन लेबल, चेतावनियां और सावधानियां)
Monitor patients for the development of edema when co-administering LYRICA CR and thiazolidinedione antidiabetic agents. (प्रीगैबलिन लेबल, चेतावनियां और सावधानियां)
Antidiabetic agents: May increase blood glucose concentrations. (प्रेडनिसोन लेबल, दवाओं के इंटरैक्शन)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (प्रेडनिसोलोन लेबल, दवाओं के इंटरैक्शन)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
• A reduction in dose of insulin or oral hypoglycemic medication may be required in some patients. (फेंटरमिन लेबल, चेतावनियां और सावधानियां)
Insulin requirements in diabetic patients may be increased, decreased, or unchanged. (फोसिनोप्रिल और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)
As is true with many other types of medication when taken concurrently by patients with diabetes, insulin and/or oral hypoglycemic, dosage may need to be adjusted when therapy with PROZAC is instituted or discontinued. (फ्लुओक्सेटिन लेबल, चेतावनियां और सावधानियां)
Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (फ्लुड्रोकॉर्टिसोन लेबल, दवाओं के इंटरैक्शन)
Nonselective beta-blockers may potentiate insulin-induced hypoglycemia and delay recovery of serum glucose levels. (बिसोप्रोलोल लेबल, चेतावनियां)
Also, latent diabetes mellitus may become manifest and diabetic patients given thiazides may require adjustment of their insulin dose. (बिसोप्रोलोल और हाइड्रोक्लोरोथायज़ाइड लेबल, चेतावनियां)
Unlike nonselective beta-blockers, betaxolol does not prolong insulin-induced hypoglycemia. (बीटाक्सोलोल लेबल, चेतावनियां)
Hypoglycemia: Consider a lower dose of insulin or insulin secretagogue to reduce risk of hypoglycemia when used in combination with bexagliflozin tablets. (बेक्साग्लिफ्लोज़िन लेबल, चेतावनियां और सावधानियां)
Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (बेक्सारोटीन लेबल, चेतावनियां और सावधानियां)
Antidiabetics: Increased risk of hypoglycemia ( 7.2 ) (बेनाज़ेप्रिल लेबल, दवाओं के इंटरैक्शन)
Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (बेनाज़ेप्रिल और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)
Oral antidiabetic agents and insulin, causing hypoglycemia by contributing an additive effect, if dosage of Butalbital, Aspirin, and Caffeine Capsules exceeds maximum recommended daily dosage. (ब्यूटाल्बिटल, एस्पिरिन और कैफीन लेबल, दवाओं के इंटरैक्शन)
Evaluate the blood pressure and renal function of patients Examples: Metoprolol, propranolol Hypoglycemic Agents Clinical Impact: Aspirin may increase the serum glucose-lowering action of insulin and sulfonylureas leading to hypoglycemia. (ब्यूटाल्बिटल, एस्पिरिन, कैफीन और कोडीन लेबल, दवाओं के इंटरैक्शन)
Masking of Hypoglycemic Symptoms in Patients with Diabetes Mellitus Beta-adrenergic blocking agents should be administered with caution in patients subject to spontaneous hypoglycemia or to diabetic patients (especially those with labile diabetes) who are receiving insulin or oral hypoglycemic agents. (ब्रिमोनिडिन और टिमोलोल लेबल, चेतावनियां और सावधानियां)
Insulin: In diabetic patients the metabolic effects of androgens may decrease blood glucose and insulin requirements. (मिथाइलटेस्टोस्टेरोन लेबल, दवाओं के इंटरैक्शन)
Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (मिथाइलप्रेडनिसोलोन लेबल, दवाओं के इंटरैक्शन)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Hypoglycemia with Concomitant Use with Insulin and Insulin Secretagogues : Increased risk of hypoglycemia when used in combination with insulin and/or an insulin secretagogue. (मेटफॉर्मिन लेबल, चेतावनियां और सावधानियां)
Insulin Clinical Impact Increased GI motility by metoclopramide may increase delivery of food to the intestines and increase blood glucose. (मेटोक्लोप्रामाइड लेबल, दवाओं के इंटरैक्शन)
Antidiabetic drugs: Dosage adjustment may be required. (मेटोप्रोलोल और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)
Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (मेटोलाज़ोन लेबल, दवाओं के इंटरैक्शन)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Antidiabetic agents Carefully monitor blood glucose. (मॉक्सीफ्लॉक्सासिन लेबल, दवाओं के इंटरैक्शन)
…Diazepam Beta-Blockers Propranolol Calcium Channel Blockers Diltiazem, nifedipine, verapamil Cardiac Glycoside Preparations Digoxin Corticosteroids Prednisone Fibrates Clofibrate Oral Hypoglycemics Sulfonylureas (e.g., glyburide, glipizide) Hormonal Contraceptives/Progestins Ethinyl estradiol, levonorgestrel Immunosuppressants Cyclosporine, tacrolimus Methylxanthines… (रिफापेंटिन लेबल, दवाओं के इंटरैक्शन)
Decrease exposure Digitoxin Decrease exposure Fluoroquinolones Pefloxacin Administered with rifampin 900 mg daily Decrease exposure Moxifloxacin , Decrease exposure Oral Hypoglycemic Agents (e.g., sulfonylureas) Glyburide Decrease exposure Rifampin may worsen glucose control of glyburide. (रिफैम्पिसिन लेबल, दवाओं के इंटरैक्शन)
For patients with type 2 diabetes mellitus, oral antidiabetic treatment dosage modifications may be needed. (रेगुलर इंसुलिन (ह्यूमन) लेबल, चेतावनियां और सावधानियां)
Hypoglycemia: Concomitant use with insulin or an insulin secretagogue may increase the risk of hypoglycemia, including severe hypoglycemia. (टिर्ज़ेपाटाइड लेबल, चेतावनियां और सावधानियां)
Hypoglycemia: Consider lowering the dosage of insulin secretagogue or insulin to reduce the risk of hypoglycemia when initiating TRADJENTA ( 5.2 ) (लिनाग्लिप्टिन लेबल, चेतावनियां और सावधानियां)
Hypoglycemia: Consider lowering the dosage of insulin secretagogue or insulin to reduce the risk of hypoglycemia when initiating JENTADUETO XR. (लिनाग्लिप्टिन और मेटफॉर्मिन लेबल, चेतावनियां और सावधानियां)
• Hypoglycemia: Postmarketing cases of symptomatic hypoglycemia have been reported in patients with diabetes mellitus receiving insulin or oral hypoglycemic agents. (लिनेज़ोलिड लेबल, चेतावनियां और सावधानियां)
• Hypoglycemia : Adult patients taking an insulin secretagogue or insulin may have an increased risk of hypoglycemia, including severe hypoglycemia. (लिराग्लूटाइड लेबल, चेतावनियां और सावधानियां)
Antidiabetics Concomitant administration of Zestril and antidiabetic medicines (insulins, oral hypoglycemic agents) may cause an increased blood-glucose-lowering effect with risk of hypoglycemia. (लिसिनोप्रिल लेबल, दवाओं के इंटरैक्शन)
Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (लिसिनोप्रिल और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Blood Glucose Disturbances Fluoroquinolones, including Levofloxacin in 5% Dextrose Injection, have been associated with disturbances of blood glucose, including symptomatic hyperglycemia and hypoglycemia, usually in diabetic patients receiving concomitant treatment with an oral hypoglycemic agent (e.g., glyburide) or with insulin. (लेवोफ्लॉक्सासिन लेबल, चेतावनियां और सावधानियां)
- लैनरियोटाइडमध्यम
Hyperglycemia and Hypoglycemia : Glucose monitoring is recommended and antidiabetic treatment adjusted accordingly. (लैनरियोटाइड लेबल, चेतावनियां और सावधानियां)
Antidiabetic drugs: dosage adjustment of antidiabetic may be required. (लोसार्टन और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)
Monitor patients on oral medications dependent on threshold concentrations for efficacy and those with a narrow therapeutic index (e.g., warfarin) when concomitantly administered with ZEPBOUND. (टिर्ज़ेपाटाइड लेबल, दवाओं के इंटरैक्शन)
Hydrochlorothiazide: When administered concurrently, the following drugs may interact with thiazide diuretics: Antidiabetic Drugs (oral agents and insulin) - Dosage adjustment of the antidiabetic drug may be required. (वाल्सार्टन और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)
- वैरेनिक्लिनमध्यम
• Effect of Smoking Cessation on Other Drugs: Pharmacokinetics or pharmacodynamics of certain drugs (e.g., theophylline, warfarin, insulin) may be altered, necessitating dose adjustment. (वैरेनिक्लिन लेबल, दवाओं के इंटरैक्शन)
Sulfonylurea Oral Hypoglycemics (CYP2C9 Inhibition) Not Studied In Vivo or In Vitro , but Drug Plasma Exposure Likely to be Increased Frequent monitoring of blood glucose and for signs and symptoms of hypoglycemia. (वोरिकोनाज़ोल लेबल, दवाओं के इंटरैक्शन)
इंसुलिन या सल्फोनिलयूरिया के साथ शराब से ब्लड शुगर कम हो सकती है, और मेटफॉर्मिन के साथ भारी मात्रा में शराब पीने से लैक्टिक एसिडोसिस का जोखिम बढ़ता है। (NIAAA, Harmful Interactions: Mixing Alcohol with Medicines)
Like other sulfonamide-containing drugs, sulfamethoxazole and trimethoprim potentiates the effect of oral hypoglycemics. (सल्फामेथॉक्साज़ोल और ट्राइमेथोप्रिम लेबल, दवाओं के इंटरैक्शन)
Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (साल्सालेट लेबल, दवाओं के इंटरैक्शन)
Hypoglycemia with Concomitant Use with Insulin or Insulin Secretagogues: Increased risk of hypoglycemia when used in combination with insulin and/or an insulin secretagogue. (सिटाग्लिप्टिन लेबल, चेतावनियां और सावधानियां)
Hypoglycemia with Concomitant Use with Insulin or Insulin Secretagogues: Increased risk of hypoglycemia when used in combination with insulin and/or an insulin secretagogue. (सिटाग्लिप्टिन और मेटफॉर्मिन लेबल, चेतावनियां और सावधानियां)
- सुनिटिनिबमध्यम
• Hypoglycemia : Check blood glucose levels regularly and assess if antidiabetic drug dose modifications are required. (सुनिटिनिब लेबल, चेतावनियां और सावधानियां)
• Hypoglycemia with Concomitant Use of Insulin Secretagogues or Insulin : May increase the risk of hypoglycemia, including severe hypoglycemia. (सेमाग्लूटाइड लेबल, चेतावनियां और सावधानियां)
• Hypoglycemia with Concomitant Use of Insulin or Insulin Secretagogues: Consider a lower dosage of insulin or insulin secretagogue when used in combination wtih Saxagliptin tablets ( 5.3 ) (सैक्साग्लिप्टिन लेबल, चेतावनियां और सावधानियां)
Insulin and Oral Antidiabetics Hyperglycemia may occur, and the dosage of insulin or antidiabetic drugs may require adjustment. (सोटालोल लेबल, दवाओं के इंटरैक्शन)
- सोमाट्रोपिनमध्यम
Glucose Intolerance and Diabetes Mellitus: HUMATROPE may decrease insulin sensitivity, particularly at higher doses. (सोमाट्रोपिन लेबल, चेतावनियां और सावधानियां)
Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (स्पिरोनोलैक्टोन और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)
Hydroxyurea may falsely elevate sensor glucose results from certain continuous glucose monitoring (CGM) systems and may lead to hypoglycemia if sensor glucose results are relied upon to dose insulin. (हाइड्रॉक्सीयूरिया लेबल, चेतावनियां और सावधानियां)
Antidiabetic Agents Clinical Impact: Corticosteroids in supraphysiologic doses may increase blood glucose concentrations. (हाइड्रोकॉर्टिसोन लेबल, दवाओं के इंटरैक्शन)
Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)
मामूली ज़िक्र (21)
Such measures include the intravenous administration of sodium bicarbonate solution or oral or parenteral glucose with a rapid-acting insulin preparation. (एमिलोराइड लेबल, चेतावनियां)
In some cases, hyperglycemia has resolved when the atypical antipsychotic was discontinued; however, some patients required continuation of antidiabetic treatment despite discontinuation of the suspect drug. (क्लोज़ापिन लेबल, चेतावनियां और सावधानियां)
In some cases, hyperglycemia has resolved when the atypical antipsychotic was discontinued; however, some patients required continuation of antidiabetic treatment despite discontinuation of the suspect drug. (ज़िप्रासिडोन लेबल, चेतावनियां और सावधानियां)
Drug Interactions with Amlodipine In clinical trials, amlodipine has been safely administered with thiazide diuretics, beta-blockers, angiotensin-converting enzyme inhibitors, long-acting nitrates, sublingual nitroglycerin, digoxin, warfarin, non-steroidal anti-inflammatory drugs, antibiotics, and oral hypoglycemic drugs. (टेल्मिसार्टन और एम्लोडिपिन लेबल, दवाओं के इंटरैक्शन)
Hypoglycemic Agents: In adult diabetic patients under treatment with either sulfonylureas or insulin there is no change in the clinical effects of either TOLECTIN or the hypoglycemic agents. (टोल्मेटिन लेबल, दवाओं के इंटरैक्शन)
Antidiabetic drug requirements (i.e., insulin) may be altered. (डाइएथिलप्रोपियॉन लेबल, दवाओं के इंटरैक्शन)
Glucose Lowering Drugs Pioglitazone: Co-administration of pioglitazone for 7 days with 30 mg nifedipine ER administered orally q.d. for 4 days to male and female volunteers resulted in least square mean (90% CI) values for unchanged nifedipine of 0.83 (0.73-0.95) for C max and 0.88 (0.80-0.96) for AUC relative to nifedipine monotherapy. (निफेडिपिन लेबल, सावधानियां)
…been administered without any adverse drug interaction in limited clinical experience to date with the following: (1) cardiac glycosides– digitalis and digoxin; (2) hypoglycemics–insulin, chlorpropamide, phenformin, tolazamide, and tolbutamide; (3) tranquilizers and sedatives–chlordiazepoxide, diazepam, and phenobarbital; (4) antigout–allopurinol, colchicine,… (प्राज़ोसिन लेबल, दवाओं के इंटरैक्शन)
Insulin and Oral Hypoglycemic Medications Requirements may be altered. (फेनडाइमेट्राज़िन लेबल, दवाओं के इंटरैक्शन)
Hyperglycemia Hyperglycemia, resulting from the drug’s inhibitory effects on insulin release, has been reported. (फेनिटोइन लेबल, चेतावनियां और सावधानियां)
Hyperglycemia Hyperglycemia, resulting from the inhibitory effect of phenytoin (the active metabolite of CEREBYX) on insulin release, has been reported. (फॉस्फेनिटोइन लेबल, चेतावनियां और सावधानियां)
Additional predisposing conditions include diabetes mellitus treated with oral hypoglycemic drugs or insulin, use of anorectic drugs, excessive use of alcohol, use of benzodiazepines, sedatives/hypnotics, or opiates. (ब्यूप्रोपियॉन लेबल, चेतावनियां और सावधानियां)
Although the systemic absorption of miconazole following ORAVIG administration is minimal and plasma concentrations of miconazole are substantially lower than when given intravenously, the potential for interaction with drugs metabolized through CYP2C9 and CYP3A4 such as oral hypoglycemics, phenytoin, or ergot alkaloids cannot be ruled out. (माइकोनाज़ोल लेबल, दवाओं के इंटरैक्शन)
…been observed in limited experience with patients in whom milrinone was used concurrently with the following drugs: digitalis glycosides; lidocaine, quinidine; hydralazine, prazosin; isosorbide dinitrate, nitroglycerin; chlorthalidone, furosemide, hydrochlorothiazide, spironolactone; captopril; heparin, warfarin, diazepam, insulin; and potassium supplements. (मिलरिनोन लेबल, दवाओं के इंटरैक्शन)
- मेकासेर्मिनमामूली
Administer INCRELEX shortly before or after a meal or snack, because it has insulin-like hypoglycemic effects. (मेकासेर्मिन लेबल, चेतावनियां और सावधानियां)
Insulin requirements in diabetes mellitus may be altered in association with the use of methamphetamine and the concomitant dietary regimen. (मेथएम्फेटामाइन लेबल, दवाओं के इंटरैक्शन)
Moexipril hydrochloride has been used in clinical trials concomitantly with calcium-channel-blocking agents, diuretics, H 2 blockers, digoxin, oral hypoglycemic agents, and cholesterol-lowering agents. (मोएक्सिप्रिल लेबल, दवाओं के इंटरैक्शन)
In an uncontrolled open-label trial of CAPLYTA for up to 1 year in adult patients with stable schizophrenia, the percentages of patients with shifts in fasting glucose and insulin values from normal to high were 8% and 12%, respectively. (लुमाटेपेरोन लेबल, चेतावनियां और सावधानियां)
Oral Hypoglycemic Agents In pharmacokinetic studies of lovastatin in hypercholesterolemic non-insulin dependent diabetic patients, there was no drug interaction with glipizide or with chlorpropamide (see CLINICAL PHARMACOLOGY , Clinical Studies in Adults ). (लोवास्टेटिन लेबल, दवाओं के इंटरैक्शन)
Administration of intravenous calcium, bicarbonate, and glucose with insulin, with hyperventilation have resulted in successful resuscitation in some of the reported cases. (सक्सिनिलकोलिन लेबल, चेतावनियां और सावधानियां)
Potentiation of the action of sulfonylurea hypoglycemic agents, thiazide diuretics and uricosuric agents may also be noted. (सल्फाडायज़िन लेबल, दवाओं के इंटरैक्शन)
कोई महत्वपूर्ण इंटरैक्शन नहीं बताया गया (3)
Glyburide Clinical Impact: While oxaprozin does alter the pharmacokinetics of glyburide, coadministration of oxaprozin to type II non-insulin dependent diabetic patients did not affect the area under the glucose concentration curve nor the magnitude or duration of control. (ऑक्साप्रोज़िन लेबल, दवाओं के इंटरैक्शन)
Other interactions: Vardenafil hydrochloride tablets had no effect on the pharmacodynamics of glyburide (glucose and insulin concentrations) and warfarin (prothrombin time or other pharmacodynamic parameters). (वार्डेनाफिल लेबल, दवाओं के इंटरैक्शन)
Oral hypoglycemic agents Although sulindac and its sulfide metabolite are highly bound to protein, studies in which sulindac was given at a dose of 400 mg daily, have shown no clinically significant interaction with oral hypoglycemic agents. (सुलिंडैक लेबल, दवाओं के इंटरैक्शन)
आप जो कुछ भी लेते हैं, उस सबके साथ टिर्ज़ेपाटाइड को जांचें। अपनी पूरी सूची जोड़ें; हर जोड़ी एक साथ जांची जाती है।
चेकर में खोलेंयह चिकित्सकीय सलाह नहीं है। गंभीरता लेबल के शब्दों को दर्शाती है, आपकी परिस्थितियों को नहीं। “गंभीर” चिह्न वाला संयोजन डॉक्टर की देखरेख में सामान्य बात हो सकता है, और “मामूली” चिह्न वाला संयोजन ऊंची खुराक पर मायने रख सकता है। फार्मासिस्ट से पूछें।