कार्बिडोपा और सेलेजिलिन का इंटरैक्शन

Nonselective monoamine oxidase (MAO) inhibitors are contraindicated for use with levodopa or carbidopa-levodopa combination products with or without carbidopa.

Carbidopa-levodopa, or levodopa may be administered concomitantly with the manufacturer’s recommended dose of an MAO inhibitor with selectivity for MAO type B (e.g., selegiline HCl) (see PRECAUTIONS, Drug Interactions ).

Concomitant therapy with selegiline or rasigiline and carbidopa or carbidopa-levodopa may be associated with severe orthostatic hypotension not attributable to carbidopa-levodopa alone (see CONTRAINDICATIONS ).

For patients receiving monoamine oxidase inhibitors (Type A or B), (see CONTRAINDICATIONS ).