सेलेजिलिन के इंटरैक्शन
हम जिन FDA लेबल और फैक्ट शीट को इंडेक्स करते हैं, उनमें सेलेजिलिन (Emsam, Zelapar, Eldepryl; MAO इनहिबिटर) के 255 इंटरैक्शन दर्ज हैं: 127 गंभीर, 120 मध्यम, 8 मामूली, और 0 ऐसे जिनमें लेबल बताता है कि कोई महत्वपूर्ण इंटरैक्शन नहीं है। नीचे की हर प्रविष्टि उस वाक्य को उद्धृत करती है जिस पर वह आधारित है। दवा का यह पेज एक शुरुआती बिंदु है, आपकी स्थिति के लिए कोई फ़ैसला नहीं।
लेबल से लिए गए इंटरैक्शन
गंभीर इंटरैक्शन (127)
• Concomitant use of other drugs in the monoamine oxidase inhibitor (MAOI) class or other drugs that are potent inhibitors of monoamine oxidase, including linezolid), because of an increased risk for hypertensive crisis [see Warnings and Precautions (5.1)]. (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
Taking, or within 14 days of stopping, a monoamine oxidase inhibitor (MAOI) [see Drug Interactions (7) ] . (एटोमोक्सेटिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
CONTRAINDICATIONS IOPIDINE 1% Ophthalmic Solution is contraindicated for patients receiving monoamine oxidase inhibitor therapy and for patients with hypersensitivity to any component of this medication or to clonidine. (एप्राक्लोनिडिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
Patients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive crisis [ see Warnings and Precautions (5.7) , Drug Interactions (7.1) ]. (एम्फेटामाइन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
Hypersensitivity reactions such as angioedema and anaphylactic reactions have been reported in patients treated with other amphetamine products [see Adverse Reactions ( 6.2 )] . taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive… (एम्फेटामाइन और डेक्सट्रोएम्फेटामाइन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
Selective Serotonin Reuptake Inhibitors/Serotonin and Norepinephrine Reuptake Inhibitors and Serotonin Syndrome Cases of serotonin syndrome have been reported during co-administration of triptans and SSRIs, SNRIs, TCAs and MAO inhibitors [see Warnings and Precautions (5.7) ]. (एलेट्रिप्टान लेबल, दवाओं के इंटरैक्शन)
• May cause serotonin syndrome when used with antidepressants (5.2) (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
Patients should be monitored for the emergence of serotonin syndrome, especially with concomitant use of Ondansetron Injection and other serotonergic drugs. (ओन्डैनसेट्रॉन लेबल, चेतावनियां और सावधानियां)
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
…serotonin reuptake inhibitors-SSRIs, serotonin-norepinephrine reuptake inhibitors-SNRIs, tricyclic antidepressants, tetracyclic antidepressants, triazolopyridine antidepressants) and a non-selective MAOI (e.g., phenelzine, tranylcypromine) or selective MAO-B inhibitors, such as selegiline (ELDEPRYL), rasagiline (AZILECT), and olanzapine (Zydis) selegiline (ZELAPAR). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
• May cause serotonin syndrome when used with antidepressants (5.2) (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Concomitant use of monoamine oxidase inhibitors (MAOIs). (कार्बामाज़ेपिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
- कार्बिडोपागंभीर
Nonselective monoamine oxidase (MAO) inhibitors are contraindicated for use with levodopa or carbidopa-levodopa combination products with or without carbidopa. (कार्बिडोपा लेबल, निषेध (कॉन्ट्राइंडिकेशन))
DUOPA is contraindicated in patients who are currently taking a nonselective monoamine oxidase (MAO) inhibitor (e.g., phenelzine and tranylcypromine) or have recently (within 2 weeks) taken a nonselective MAO inhibitor. (कार्बिडोपा और लेवोडोपा लेबल, निषेध (कॉन्ट्राइंडिकेशन))
Carbidopa, levodopa and entacapone tablets is contraindicated in patients: Taking nonselective monoamine oxidase (MAO) inhibitors (e.g., phenelzine and tranylcypromine). (कार्बिडोपा, लेवोडोपा और एंटाकैपोन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
…because deaths have been reported in this age group [see Warnings and Precautions (5.1)]. patients who are hypersensitive to carbinoxamine maleate or any of the inactive ingredients in Carbinoxamine Maleate Extended-Release Oral Suspension [see Warnings and Precautions (5.4)]. patients who are taking monoamine oxidase inhibitors (MAOI) [see Drug Interactions (7)]. (कार्बिनोक्सामिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
Patients should be monitored for the emergence of serotonin syndrome, especially with concomitant use of granisetron and other serotonergic drugs. (ग्रैनिसेट्रॉन लेबल, चेतावनियां और सावधानियां)
• Concomitant use of monoamine oxidase inhibitors (MAOIs), or use within 14 days of stopping MAOIs. (ज़िप्रासिडोन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
• Taking monoamine oxidase inhibitors (MAOIs). (टेट्राबेनाज़िन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
• May cause serotonin syndrome when used with antidepressants (5.2) (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
…serotonin reuptake inhibitors-SSRIs, serotonin-norepinephrine reuptake inhibitors-SNRIs, tricyclic antidepressants, tetracyclic antidepressants, triazolopyridine antidepressants) and a non-selective MAOI (e.g., phenelzine, tranylcypromine) or selective MAO-B inhibitors, such as selegiline (ELDEPRYL), rasagiline (AZILECT), and olanzapine (Zydis) selegiline (ZELAPAR). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
During or within 14 days following the administration of monoamine oxidase inhibitors, hypertensive crises may result. (डाइएथिलप्रोपियॉन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
Avoid use of diphenoxylate hydrochloride and atropine sulfate in patients who take MAOIs and monitor for signs and symptoms of hypertensive crisis (headache, hyperthermia, hypertension). (डाइफेनोक्सिलेट और एट्रोपिन लेबल, दवाओं के इंटरैक्शन)
• May cause serotonin syndrome when used with antidepressants (5.2) (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Antihistamines are also contraindicated in the following conditions: Hypersensitivity to dexchlorpheniramine maleate or other antihistamines of similar chemical structure Monoamine oxidase inhibitor therapy (See Drug Interaction section) (डेक्सक्लोरफेनिरामिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
Patients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive crisis [see Warnings and Drug Interactions ]. (डेक्सट्रोएम्फेटामाइन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
• Concomitant use of dextromethorphan, because of reported episodes of psychosis or bizarre behavior. (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
• Concomitant use of dextromethorphan, because of reported episodes of psychosis or bizarre behavior. (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
• Concomitant treatment with monoamine oxidase inhibitors (MAOIs) or within 14 days following discontinuation of treatment with an MAOI, because of the risk of hypertensive crises [see Drug Interactions ( 7.1 )] . (डेक्समिथाइलफेनिडेट लेबल, निषेध (कॉन्ट्राइंडिकेशन))
• May cause serotonin syndrome when used with antidepressants (5.2) (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
…Known hypersensitivity to doxylamine succinate, other ethanolamine derivative antihistamines, pyridoxine hydrochloride or any inactive ingredient in the formulation Monoamine oxidase (MAO) inhibitors intensify and prolong the adverse central nervous system effects of doxylamine succinate and pyridoxine hydrochloride delayed-release tablets [ see Drug Interactions… (डॉक्सीलामिन और पाइरिडोक्सिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
Taking monoamine oxidase inhibitors (MAOIs). (ड्यूटेट्राबेनाज़िन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
However, based on mechanism of action, the use of non-selective MAO inhibitors and linezolid should be avoided as there is a potential for increased blood pressure when taken with NORTHERA. (ड्रॉक्सीडोपा लेबल, दवाओं के इंटरैक्शन)
Selective Serotonin Reuptake Inhibitors/Serotonin Norepinephrine Reuptake Inhibitors and Serotonin Syndrome Cases of serotonin syndrome have been reported during co-administration of triptans and SSRIs, SNRIs, TCAs, and MAO inhibitors [see Warnings and Precautions (5.7)] . (नाराट्रिप्टान लेबल, दवाओं के इंटरैक्शन)
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
• May cause serotonin syndrome when used with antidepressants (5.2) (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
• May cause serotonin syndrome when used with antidepressants (5.2) (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
• May cause serotonin syndrome when used with antidepressants (5.2) (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Patients should be monitored for the emergence of serotonin syndrome, especially with concomitant use of POSFREA and other serotonergic drugs. (पैलोनोसेट्रॉन लेबल, चेतावनियां और सावधानियां)
John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
• Concomitant use of dextromethorphan, because of reported episodes of psychosis or bizarre behavior. (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
…cardiovascular disease (e.g., coronary artery disease, stroke, arrhythmias, congestive heart failure, uncontrolled hypertension) • During or within 14 days following the administration of monoamine oxidase inhibitors • Hyperthyroidism • Glaucoma • Agitated states • History of drug abuse • Pregnancy [ see Use in Specific Populations () ] • Nursing [ see Use in Specific… (फेंटरमिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
…Warnings and Precautions (5.1) and Use in Specific Populations (8.1) ] With glaucoma [see Warnings and Precautions (5.3) ] With hyperthyroidism Taking or within 14 days of stopping a monoamine oxidase inhibitors [see Drug Interactions (7) ] With known hypersensitivity to phentermine, topiramate or any of the excipients in phentermine and topiramate extended-release… (फेंटरमिन और टोपिरामेट लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
…coronary artery disease, stroke, arrhythmias, congestive heart failure, uncontrolled hypertension, pulmonary hypertension) • During or within 14 days following the administration of monoamine oxidase inhibitors • Hyperthyroidism • Glaucoma • Agitated states • History of drug abuse • Pregnancy (see PRECAUTIONS, Pregnancy ) • Nursing • Use in combination with other… (फेनडाइमेट्राज़िन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
• Concomitant use of other drugs in the monoamine oxidase inhibitor (MAOI) class or other drugs that are potent inhibitors of monoamine oxidase, including linezolid), because of an increased risk for hypertensive crisis [see Warnings and Precautions (5.1)]. (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
Selective Serotonin Reuptake Inhibitors / Serotonin Norepinephrine Reuptake Inhibitors and Serotonin Syndrome Cases of serotonin syndrome have been reported during combined use of triptans and SSRIs, SNRIs, TCAs, and MAO inhibitors [ see Warnings and Precautions (5.7) ]. (फ्रोवाट्रिप्टान लेबल, दवाओं के इंटरैक्शन)
• May cause serotonin syndrome when used with antidepressants (5.2) (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
• May cause serotonin syndrome when used with antidepressants (5.2) (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
The use of monoamine oxidase inhibitors (MAOIs) intended to treat depression with buspirone or within 14 days of stopping treatment with buspirone is contraindicated because of an increased risk of serotonin syndrome and/or elevated blood pressure. (बस्पिरोन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
Hypertensive crises have resulted when sympathomimetic amines have been used concomitantly or within 14 days following use of monoamine oxidase inhibitors. (बेंज़फेटामाइन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
• May cause serotonin syndrome when used with antidepressants (5.2) (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
• Concomitant use of dextromethorphan, because of reported episodes of psychosis or bizarre behavior. (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
Avoid use of MAO inhibitors or linezolid with midodrine. (मिडोड्रिन लेबल, दवाओं के इंटरैक्शन)
CONTRAINDICATIONS Methyldopa is contraindicated in patients: – with active hepatic disease, such as acute hepatitis and active cirrhosis. – with liver disorders previously associated with methyldopa therapy (see WARNINGS ). – with hypersensitivity to any component of this product. – on therapy with monoamine oxidase (MAO) inhibitors. (मिथाइलडोपा लेबल, निषेध (कॉन्ट्राइंडिकेशन))
Concomitant treatment with monoamine oxidase inhibitors (MAOIs), and also within a minimum of 14 days following discontinuation of treatment with a monoamine oxidase inhibitor because of the risk of hypertensive crisis [see Drug Interactions (7.1) ]. (मिथाइलफेनिडेट लेबल, निषेध (कॉन्ट्राइंडिकेशन))
• Concomitant use of other drugs in the monoamine oxidase inhibitor (MAOI) class or other drugs that are potent inhibitors of monoamine oxidase, including linezolid), because of an increased risk for hypertensive crisis [see Warnings and Precautions (5.1)]. (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
• May cause serotonin syndrome when used with antidepressants (5.2) (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
• Serotonin Syndrome and MAOIs: Do not use MAOIs intended to treat psychiatric disorders with milnacipran hydrochloride or within 5 days of stopping treatment with milnacipran hydrochloride. (मिल्नासिप्रान लेबल, निषेध (कॉन्ट्राइंडिकेशन))
John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
In one study in hypertensive patients, intravenously administered metoclopramide was shown to release catecholamines; hence, avoid use in patients with hypertension or in patients taking monoamine oxidase inhibitors [see Drug Interactions ( 7.1 )] . (मेटोक्लोप्रामाइड लेबल, चेतावनियां और सावधानियां)
Hypersensitivity reactions such as angioedema and anaphylactic reactions have been reported in patients treated with other amphetamine products [see Adverse Reactions ( 6 )]. taking monoamine oxidase inhibitors (MAOIs), or within 14 days following discontinuation of treatment with an MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because… (मेथएम्फेटामाइन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
…serotonin reuptake inhibitors-SSRIs, serotonin-norepinephrine reuptake inhibitors-SNRIs, tricyclic antidepressants, tetracyclic antidepressants, triazolopyridine antidepressants) and a non-selective MAOI (e.g., phenelzine, tranylcypromine) or selective MAO-B inhibitors, such as selegiline (ELDEPRYL), rasagiline (AZILECT), and olanzapine (Zydis) selegiline (ZELAPAR). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Monoamine Oxidase Inhibitors MAXALT is contraindicated in patients taking MAO-A inhibitors and non-selective MAO inhibitors. (रिज़ाट्रिप्टान लेबल, दवाओं के इंटरैक्शन)
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
If concomitant use of lithium with other serotonergic drugs is clinically warranted, inform patients of the increased risk for serotonin syndrome and monitor for symptoms. (लिथियम लेबल, चेतावनियां और सावधानियां)
MAO Inhibitors ZELAPAR is contraindicated for concomitant use with other drugs in the MAOI class or other drugs that are potent inhibitors of monoamine oxidase (including linezolid, an oxazolidinone antibacterial, which also has reversible nonselective MAO inhibition activity) because of the increased risk for hypertensive crisis [see Contraindications (4) and… (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Patients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive crisis [see Warnings and Precautions (5.7) and Drug Interactions (7.1) ] . (लिसडेक्सएम्फेटामाइन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
INBRIJA is contraindicated in patients currently taking a nonselective monoamine oxidase (MAO) inhibitor (e.g., phenelzine and tranylcypromine) or who have recently (within 2 weeks) taken a nonselective MAO inhibitor. (लेवोडोपा लेबल, निषेध (कॉन्ट्राइंडिकेशन))
• May cause serotonin syndrome when used with antidepressants (5.2) (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Dose adjustments due to drug interactions ( 2.4 , 7.1 ): Factors Dose Adjustments for INGREZZA and INGREZZA SPRINKLE Use of MAOIs with INGREZZA or INGREZZA SPRINKLE Avoid concomitant use with MAOIs. (वाल्बेनाज़िन लेबल, दवाओं के इंटरैक्शन)
• May cause serotonin syndrome when used with antidepressants (5.2) (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Qelbree is contraindicated in patients: receiving concomitant treatment with monoamine oxidase inhibitors (MAOI), or within 14 days following discontinuing an MAOI, because of an increased risk of hypertensive crisis [see Drug Interactions (7.1) ] . receiving concomitant administration of sensitive CYP1A2 substrates or CYP1A2 substrates with a narrow therapeutic… (विलोक्साज़िन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
• May cause serotonin syndrome when used with antidepressants (5.2) (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
• May cause serotonin syndrome when used with antidepressants (5.2) (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
• May cause serotonin syndrome when used with antidepressants (5.2) (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
Monoamine oxidase inhibitor therapy (See DRUG INTERACTIONS ). (साइप्रोहेप्टाडीन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
• May cause serotonin syndrome when used with antidepressants (5.2) (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Selective Serotonin Reuptake Inhibitors/Serotonin Norepinephrine Reuptake Inhibitors and Serotonin Syndrome Cases of serotonin syndrome have been reported during coadministration of triptans and SSRIs, SNRIs, TCAs, and MAO inhibitors [see Warnings and Precautions (5.7)] . (सुमाट्रिप्टान लेबल, दवाओं के इंटरैक्शन)
Selective Serotonin Reuptake Inhibitors/Serotonin Norepinephrine Reuptake Inhibitors and Serotonin Syndrome Clinical Impact: Cases of serotonin syndrome have been reported during coadministration of triptans and SSRIs, SNRIs, TCAs, and MAO inhibitors [see Warnings and Precautions (5.11)] . (सुमाट्रिप्टान और नेप्रोक्सेन लेबल, दवाओं के इंटरैक्शन)
सेंट जॉन्स वॉर्ट को एंटीडिप्रेसेंट और अन्य सेरोटोनर्जिक दवाओं के साथ लेने से सेरोटोनिन सिंड्रोम का जोखिम बढ़ता है। (NCCIH, St. John's Wort)
SUNOSI is contraindicated in patients receiving concomitant treatment with monoamine oxidase (MAO) inhibitors, or within 14 days following discontinuation of monoamine oxidase inhibitor, because of the risk of hypertensive reaction [see Drug Interactions ( 7.1 )] . (सोलरियमफेटोल लेबल, निषेध (कॉन्ट्राइंडिकेशन))
Warnings Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. (स्यूडोएफेड्रिन लेबल, चेतावनियां)
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (सेलेजिलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))
मध्यम इंटरैक्शन (120)
Dyskinesia ZELAPAR may potentiate dopaminergic side effects of levodopa and may cause dyskinesia or exacerbate preexisting dyskinesia. (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Concomitant Use with MAO Inhibitors Concomitant use of MAO inhibitors and inhalational anesthetics may increase the risk of hemodynamic instability during surgery or medical procedures. (आइसोफ्लुरेन लेबल, दवाओं के इंटरैक्शन)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analog (e.g., octreotide), and sulfonamide antibiotics. (इंसुलिन एस्पार्ट लेबल, दवाओं के इंटरैक्शन)
…Glargine-yfgn Drugs that May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors,… (इंसुलिन ग्लार्जिन लेबल, दवाओं के इंटरैक्शन)
…Degludec Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors,… (इंसुलिन डेग्लुडेक लेबल, दवाओं के इंटरैक्शन)
…with LEVEMIR Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors,… (इंसुलिन डेटेमिर लेबल, दवाओं के इंटरैक्शन)
Clinically Significant Drug Interactions with LYUMJEV Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics. (इंसुलिन लिस्प्रो लेबल, दवाओं के इंटरैक्शन)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
The action of the benzodiazepines may be potentiated by anticonvulsants, antihistamines, alcohol, barbiturates, monoamine oxidase inhibitors, narcotics, phenothiazines, psychotropic medications, or other drugs that produce CNS depression. (एस्टाज़ोलम लेबल, दवाओं के इंटरैक्शन)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Hypotensive agents (e.g., reserpine, MAO inhibitors, clonidine) may increase the risk of hypotension and/or severe bradycardia. (कार्वेडिलोल लेबल, दवाओं के इंटरैक्शन)
Dyskinesia ZELAPAR may potentiate dopaminergic side effects of levodopa and may cause dyskinesia or exacerbate preexisting dyskinesia. (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Monoamine-oxidase inhibitors: Concomitant administration may potentiate the effects and toxicity of monoamine-oxidase inhibitors. (कोकेन लेबल, दवाओं के इंटरैक्शन)
Monoamine oxidase (MAO) inhibitors prolong and intensify the anticholinergic effects of antihistamines. (क्लेमास्टिन लेबल, दवाओं के इंटरैक्शन)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
…Interactions The CNS-depressant action of the benzodiazepine class of drugs may be potentiated by alcohol, narcotics, barbiturates, nonbarbiturate hypnotics, antianxiety agents, the phenothiazines, thioxanthene and butyrophenone classes of antipsychotic agents, monoamine oxidase inhibitors and the tricyclic antidepressants, and by other anticonvulsant drugs. (क्लोनाज़ेपाम लेबल, दवाओं के इंटरैक्शन)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
The actions of the benzodiazepines may be potentiated by barbiturates, narcotics, phenothiazines, monoamine oxidase inhibitors or other antidepressants. (क्लोराज़ेपेट लेबल, दवाओं के इंटरैक्शन)
Drug Interactions The administration of local anesthetic solutions containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors, tricyclic antidepressants or phenothiazines may produce severe, prolonged hypotension or hypertension. (क्लोरोप्रोकेन लेबल, सावधानियां)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
…increase the susceptibility to and/or intensity of hypoglycemia: antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analogs (e.g., octreotide), sulfonamide antibiotics, nonsteroidal anti-inflammatory… (ग्लिपिज़ाइड लेबल, दवाओं के इंटरैक्शन)
Glipizide: The hypoglycemic action of sulfonylureas may be potentiated by certain drugs, including nonsteroidal anti-inflammatory agents, some azoles, and other drugs that are highly protein bound, salicylates, sulfonamides, chloramphenicol, probenecid, coumarins, monoamine oxidase inhibitors, and beta-adrenergic blocking agents. (ग्लिपिज़ाइड और मेटफॉर्मिन लेबल, सावधानियां)
…Interactions The hypoglycemic action of sulfonylureas may be potentiated by certain drugs including nonsteroidal anti-inflammatory agents, ACE inhibitors, disopyramide, fluoxetine, clarithromycin, and other drugs that are highly protein bound, salicylates, sulfonamides, chloramphenicol, probenecid, monoamine oxidase inhibitors, and beta adrenergic blocking agents. (ग्लिबेनक्लामाइड लेबल, दवाओं के इंटरैक्शन)
…steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides, chloramphenicol, coumarins, probenecid and monoamine oxidase inhibitors. (ग्लिमेपिराइड लेबल, दवाओं के इंटरैक्शन)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
- टोलकैपोनमध्यम
Baseline treatment with dopamine agonists or selegiline did not appear to increase the likelihood of experiencing orthostatic hypotension when treated with Tolcapone tablets. (टोलकैपोन लेबल, सावधानियां)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
MAO inhibitors prolong and intensify the anticholinergic (drying) effects of antihistamines. (डाइफेनहाइड्रामिन लेबल, दवाओं के इंटरैक्शन)
…drugs including dicyclomine hydrochloride: amantadine, antiarrhythmic agents of Class I (e.g., quinidine), antihistamines, antipsychotic agents (e.g., phenothiazines), benzodiazepines, MAO inhibitors, narcotic analgesics (e.g., meperidine), nitrates and nitrites, sympathomimetic agents, tricyclic antidepressants, and other drugs having anticholinergic activity. (डाइसाइक्लोमिन लेबल, दवाओं के इंटरैक्शन)
…be given to the pharmacology of the agents employed particularly with compounds that may potentiate or be potentiated by the action of Valium, such as phenothiazines, antipsychotics, anxiolytics/sedatives, hypnotics, anticonvulsants, narcotic analgesics, anesthetics, sedative antihistamines, narcotics, barbiturates, MAO inhibitors and other antidepressants. (डायज़ेपाम लेबल, दवाओं के इंटरैक्शन)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
…1) clinically significant bradycardia (less than 50 bpm), 2) any clinically significant cardiac disease, 3) treatment with Class I and Class III antiarrhythmics, 4) treatment with monoamine oxidase inhibitors (MAOI's), 5) concomitant treatment with other drug products known to prolong the QT interval (see PRECAUTIONS, Drug Interactions ), and 6) electrolyte imbalance,… (ड्रोपेरिडोल लेबल, चेतावनियां)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
…Nateglinide Drugs That May Increase the Blood-Glucose-Lowering Effect of Nateglinide and Susceptibility to Hypoglycemia Drugs: Nonsteroidal anti-inflammatory drugs (NSAIDs), salicylates, monoamine oxidase inhibitors, non-selective beta-adrenergic-blocking agents, anabolic hormones (e.g., methandrostenolone), guanethidine, gymnema sylvestre, glucomannan, thioctic acid,… (नेटेग्लिनाइड लेबल, दवाओं के इंटरैक्शन)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
…steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides, chloramphenicol, coumarins, probenecid and monoamine oxidase inhibitors. (पियोग्लिटाज़ोन और ग्लिमेपिराइड लेबल, दवाओं के इंटरैक्शन)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Dyskinesia ZELAPAR may potentiate dopaminergic side effects of levodopa and may cause dyskinesia or exacerbate preexisting dyskinesia. (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Monoamine Oxidase Inhibitors (MAOI) Drug interactions, including an increased incidence of extrapyramidal effects, have been reported when some MAOI and phenothiazines are used concomitantly. (प्रोमेथाज़िन लेबल, दवाओं के इंटरैक्शन)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Drug Interactions The CNS effects of butalbital may be enhanced by monoamine oxidase (MAO) inhibitors. (ब्यूटाल्बिटल और पैरासिटामोल लेबल, दवाओं के इंटरैक्शन)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
…of Adverse Reactions Due to Drug Interactions with MARCAINE WITH EPINEPHRINE Risk of Severe, Persistent Hypertension Due to Drug Interactions Between MARCAINE WITH EPINEPHRINE and Monoamine Oxidase Inhibitors and Tricyclic Antidepressants Administration of MARCAINE WITH EPINEPHRINE (containing a vasoconstrictor) in patients receiving monoamine oxidase inhibitors… (ब्यूपिवाकेन लेबल, चेतावनियां और सावधानियां)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Monoamine oxidase inhibitors may result in increased hypotension. (ब्रिमोनिडिन लेबल, दवाओं के इंटरैक्शन)
Monoamine oxidase inhibitors may result in increased hypotension. (ब्रिमोनिडिन और टिमोलोल लेबल, दवाओं के इंटरैक्शन)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Dyskinesia ZELAPAR may potentiate dopaminergic side effects of levodopa and may cause dyskinesia or exacerbate preexisting dyskinesia. (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Catecholamine depleting drugs (e.g., reserpine, monoamine oxidase (MAO) inhibitors) may have an additive effect when given with beta-blocking agents. (मेटोप्रोलोल लेबल, दवाओं के इंटरैक्शन)
Catecholamine-depleting drugs (e.g., MAO inhibitors): Hypotension, bradycardia. (मेटोप्रोलोल और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)
Likewise, solutions of mepivacaine containing a vasoconstrictor, such as epinephrine, should be used with extreme caution in patients receiving monoamine oxidase inhibitors (MAOI) or antidepressants of the triptyline or imipramine types, because severe prolonged hypertension may result. (मेपिवाकेन लेबल, चेतावनियां)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
…Significant Drug Interactions with AFREZZA Antidiabetic agents, Angiotensin-Converting Enzyme Inhibitors, Angiotensin II Receptor Blocking Agents, Disopyramide, Fibrates, Fluoxetine, Monoamine Oxidase Inhibitors, Pentoxifylline, Pramlintide, Salicylates, Somatostatin Analogs (e.g., octreotide), and Sulfonamide Antibiotics Prevention or Management Monitor blood glucose… (रेगुलर इंसुलिन (ह्यूमन) लेबल, दवाओं के इंटरैक्शन)
Dyskinesia ZELAPAR may potentiate dopaminergic side effects of levodopa and may cause dyskinesia or exacerbate preexisting dyskinesia. (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Clinically Significant Drug Interactions The administration of local anesthetic solutions containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors or tricyclic antidepressants may produce severe, prolonged hypertension. (लिडोकेन लेबल, दवाओं के इंटरैक्शन)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
The neuromuscular blocking effect of succinylcholine may be enhanced by drugs that reduce plasma cholinesterase activity (e.g., chronically administered oral contraceptives, glucocorticoids, or certain monoamine oxidase inhibitors) or by drugs that irreversibly inhibit plasma cholinesterase [see Warnings and Precautions (5.9) ]. (सक्सिनिलकोलिन लेबल, दवाओं के इंटरैक्शन)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (सेलेजिलिन लेबल, दवाओं के इंटरैक्शन)
Non-selective MAO-inhibitors Concomitant use of MAO inhibitors and inhalational anesthetics may increase the risk of hemodynamic instability during surgery or medical procedures. (सेवोफ्लुरेन लेबल, दवाओं के इंटरैक्शन)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
Drug Interactions MAO inhibitors should be used with caution in patients receiving hydralazine. (हाइड्रालाज़िन लेबल, दवाओं के इंटरैक्शन)
Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (सेलेजिलिन लेबल, चेतावनियां और सावधानियां)
मामूली ज़िक्र (8)
- एंटाकैपोनमामूली
Entacapone can be taken concomitantly with a selective MAO-B inhibitor (e.g., selegiline). (एंटाकैपोन लेबल, चेतावनियां)
Examples: Nonsteroidal anti-inflammatory agents and other highly protein-boind drugs, salicylcates, sulfonamides, chloramphenicol, probenecid, coumarins, monoamine oxidase inhibitors, beta-adrenergic blocking agents; potentially with ciprofloxacin, micronazole. (ग्लिबेनक्लामाइड और मेटफॉर्मिन लेबल, दवाओं के इंटरैक्शन)
Serotonin Syndrome Serotonin syndrome may occur with triptans, including zolmitriptan, particularly during co-administration with selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), and MAO inhibitors [see Drug Interactions ( 7.5 )] . (ज़ोल्मिट्रिप्टान लेबल, चेतावनियां और सावधानियां)
Drugs predominantly metabolized by the CYP450 2D6 isozyme include the following drug classes: tricyclic antidepressants, selective serotonin reuptake inhibitors, beta-blockers, antiarrhythmics class 1C (e.g., flecainide and propafenone) and monoamine oxidase inhibitors Type B. (टर्बिनाफिन लेबल, दवाओं के इंटरैक्शन)
Monoamine oxidase inhibitors and tricyclic antidepressants possessing significant anticholinergic activity may intensify the anticholinergic effects of antidyskinetic agents because of the secondary anticholinergic activities of these medications. (ट्राइहेक्सीफेनिडिल लेबल, दवाओं के इंटरैक्शन)
- डाइफेनॉक्सिन और एट्रोपिनमामूली
Drug Interactions Since the chemical structure of difenoxin hydrochloride is similar to meperidine hydrochloride, the concurrent use of MOTOFEN ® with monoamine oxidase inhibitors may, in theory, precipitate a hypertensive crisis. (डाइफेनॉक्सिन और एट्रोपिन लेबल, दवाओं के इंटरैक्शन)
Antidepressants: The hypotensive effect of MAO inhibitors or tricyclic antidepressants may be exacerbated when administered with beta-blockers. (प्रोप्रानोलोल लेबल, दवाओं के इंटरैक्शन)
Examples: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, nonsteroidal anti-inflammatory agents (NSAIDs), pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics. (रेपाग्लिनाइड लेबल, दवाओं के इंटरैक्शन)
आप जो कुछ भी लेते हैं, उस सबके साथ सेलेजिलिन को जांचें। अपनी पूरी सूची जोड़ें; हर जोड़ी एक साथ जांची जाती है।
चेकर में खोलेंयह चिकित्सकीय सलाह नहीं है। गंभीरता लेबल के शब्दों को दर्शाती है, आपकी परिस्थितियों को नहीं। “गंभीर” चिह्न वाला संयोजन डॉक्टर की देखरेख में सामान्य बात हो सकता है, और “मामूली” चिह्न वाला संयोजन ऊंची खुराक पर मायने रख सकता है। फार्मासिस्ट से पूछें।