डॉक्साज़ोसिन और सिलोडोसिन का इंटरैक्शन

Silodosin capsules should not be used in combination with other alpha-blockers.

However, interactions may be expected, and silodosin capsules should not be used in combination with other alpha-blockers [see DRUG INTERACTIONS (7.3) ].

However, patients in the Phase 3 clinical studies taking concomitant antihypertensive medications with silodosin capsules did not experience a significant increase in the incidence of syncope, dizziness, or orthostasis.

Nevertheless, exercise caution during concomitant use with antihypertensives and monitor patients for possible adverse events [see ADVERSE REACTIONS (6.1)

Exercise caution during concomitant use with antihypertensives and monitor patients for possible adverse events [see WARNINGS AND PRECAUTIONS (5.5) ].

As with other alpha-blockers, there is a potential for syncope, especially after the initial dose or after an increase in dosage strength.