एडोक्साबैन और टैमोक्सीफेन का इंटरैक्शन

For women with DCIS and for the reduction in breast cancer incidence in women at high risk, tamoxifen is contraindicated in women who require concomitant warfarin-type anticoagulant therapy or in women with a history of deep vein thrombosis or pulmonary embolus.

Closely monitor coagulation indices for increased anticoagulant effect when used with tamoxifen for metastatic breast cancer or as adjuvant therapy.

Warfarin A marked increase in anticoagulant effect may occur when tamoxifen is used in combination with warfarin.