एथिनोडिओल डाइएसीटेट और एथिनिल एस्ट्राडियोल और फ्लुड्रोकॉर्टिसोन का इंटरैक्शन

Estrogen —increased levels of corticosteroid-binding globulin thereby increasing the bound (inactive) fraction; this effect is at least balanced by decreased metabolism of corticosteroids.

When estrogen therapy is initiated, a reduction in corticosteroid dosage may be required, and increased amounts may be required when estrogen is terminated.

The amount of both steroids should be considered in the choice of an oral contraceptive.

Free T 3 resin uptake is decreased, reflecting the elevated TBG; free T 4 concentration is unaltered. c) Other binding proteins may be elevated in the serum. d) Sex-steroid binding globulins are increased and result in elevated levels of total circulating sex steroids and corticoids; however, free or biologically active levels remain unchanged. e) Triglycerides…