Interaksi Tretinoin

Tretinoin (Retin-A, Renova, Altreno), golongan retinoid, memiliki 106 interaksi terdokumentasi dalam label FDA dan lembar fakta yang kami indeks: 96 mayor, 9 moderat, 1 minor, dan 0 dengan label yang melaporkan tidak ada interaksi bermakna. Setiap entri di bawah ini mengutip kalimat yang mendasarinya. Halaman obat ini adalah titik awal, bukan putusan untuk situasi Anda.

Interaksi dari label

Interaksi mayor (96)

  • AdapalenretinoidMayor

    Tretinoin capsules are contraindicated in patients with a known hypersensitivity to tretinoin capsules, any of its components, or other retinoids. (label Tretinoin, Kontraindikasi)

  • AmiodaronantiaritmiaMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • Aprepitantpenghambat CYP3A4Mayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • Armodafinilstimulan SSPMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • Asam aminokaproatantifibrinolitikMayor

    Avoid concomitant use of tretinoin capsules and anti-fibrinolytic agents, such as tranexamic acid, aminocaproic acid or aprotinin [see Drug Interactions ( 7.4 )] . (label Tretinoin, Peringatan dan perhatian)

  • Asam traneksamatantifibrinolitikMayor

    Avoid concomitant use of tretinoin capsules and anti-fibrinolytic agents, such as tranexamic acid, aminocaproic acid or aprotinin [see Drug Interactions ( 7.4 )] . (label Tretinoin, Peringatan dan perhatian)

  • AsitretinretinoidMayor

    Tretinoin capsules are contraindicated in patients with a known hypersensitivity to tretinoin capsules, any of its components, or other retinoids. (label Tretinoin, Kontraindikasi)

  • AtazanavirantiretroviralMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • Azelastin dan flutikasonantihistaminMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • BeklometasonkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • BeksarotenretinoidMayor

    Tretinoin capsules are contraindicated in patients with a known hypersensitivity to tretinoin capsules, any of its components, or other retinoids. (label Tretinoin, Kontraindikasi)

  • BetametasonkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • Bosentanpenginduksi CYP3A4Mayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • BudesonidkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • Budesonid dan formoterolkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • DarunavirantiretroviralMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • Darunavir dan kobisistatantiretroviralMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • Deferasirokssuplemen zat besiMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • DeflazakortkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • DeksametasonkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • DesonidkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • Diltiazempenghambat kanal kalsiumMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • DronedaronantiaritmiaMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • EfavirenzantiretroviralMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • Eritromisinantibiotik makrolidaMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • EslikarbazepinantikonvulsanMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • EtravirinantiretroviralMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • EverolimusimunosupresanMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • FenitoinantikonvulsanMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • FenobarbitalbarbituratMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • Fentermin dan topiramatstimulan SSPMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • FludrokortisonkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • Flukonazolantijamur azolMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • FlunisolidkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • FluosinonidkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • FlutikasonkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • Flutikason dan salmeterolkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • FosamprenavirantiretroviralMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • Fosaprepitantpenghambat CYP3A4Mayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • FosfenitoinantikonvulsanMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • GriseofulvinantijamurMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • HalobetasolkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • HidrokortisonkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • HidroksiureaantimetabolitMayor

    • Leukocytosis: Consider administering cytoreductive chemotherapy (including an anthracycline if not contraindicated or hydroxyurea) with tretinoin capsules in the setting of leukocytosis, as clinically indicated. (label Tretinoin, Peringatan dan perhatian)

  • Imatinibpenghambat CYP3A4Mayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • IsoniazidantibiotikMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • IsotretinoinretinoidMayor

    Tretinoin capsules are contraindicated in patients with a known hypersensitivity to tretinoin capsules, any of its components, or other retinoids. (label Tretinoin, Kontraindikasi)

  • Itrakonazolantijamur azolMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • Ivakaftorpenghambat CYP3A4Mayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • KarbamazepinantikonvulsanMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • Ketokonazolantijamur azolMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • Klaritromisinantibiotik makrolidaMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • KlobazambenzodiazepinMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • KlobetasolkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • LenakapavirantiretroviralMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • Lopinavir dan ritonavirantiretroviralMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • Lorlatinibpenginduksi CYP3A4Mayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • MetilprednisolonkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • Mifepristonpenghambat CYP3A4Mayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • Minosiklinantibiotik tetrasiklinMayor

    Avoid concomitant use of isotretinoin and EMROSI because isotretinoin, a systemic retinoid, is also known to cause idiopathic intracranial hypertension. (label Minosiklin, Peringatan dan perhatian)

  • Mirabegronagonis beta-adrenergikMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • Mitapivatpenginduksi CYP3A4Mayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • Mitotanpenginduksi CYP3A4Mayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • Modafinilstimulan SSPMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • MometasonkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • Nafsilinantibiotik penisilinMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • NefazodonantidepresanMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • NevirapinantiretroviralMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • OkskarbazepinantikonvulsanMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • Olopatadin dan mometasonantihistaminMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • Palbosiklibpenghambat CYP3A4Mayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • PerampanelantikonvulsanMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • Posakonazolantijamur azolMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • PrednisolonkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • PrednisonkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • PrimidonantikonvulsanMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • Ranolazinobat yang memperpanjang interval QTMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • RifabutinantibiotikMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • RifampisinantibiotikMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • RifapentinantibiotikMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • RitonavirantiretroviralMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • SenobamatantikonvulsanMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • SiklesonidkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • SiklosporinimunosupresanMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • Simetidinpenghambat H2Mayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • Suvoreksantsedatif-hipnotikMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • Suzetriginpenginduksi CYP3A4Mayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • Tetrasiklinantibiotik tetrasiklinMayor

    Concomitant use of isotretinoin and tetracycline should be avoided because isotretinoin, a systemic retinoid, is also known to cause pseudotumor cerebri. (label Tetrasiklin, Peringatan)

  • TikagrelorantiplateletMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • TopiramatantikonvulsanMayor

    Avoid concomitant use with strong CYP3A inducers if possible. (label Tretinoin, Interaksi obat)

  • TriamsinolonkortikosteroidMayor

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (label Tretinoin, Peringatan kotak hitam)

  • Verapamilpenghambat kanal kalsiumMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

  • Vorikonazolantijamur azolMayor

    • Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. (label Tretinoin, Interaksi obat)

Interaksi moderat (9)

  • Arsen trioksidaobat yang memperpanjang interval QTModerat

    Hepatotoxicity: Elevated aspartate aminotransferase (AST), alkaline phosphatase and serum bilirubin have occurred in patients with newly-diagnosed low-risk APL treated with arsenic trioxide in combination with tretinoin. (label Arsen trioksida, Peringatan dan perhatian)

  • The concomitant use of other products (e.g., tetracyclines) that can cause intracranial hypertension may increase the risk. (label Tretinoin, Peringatan dan perhatian)

  • Demeklosiklinantibiotik tetrasiklinModerat

    The concomitant use of other products (e.g., tetracyclines) that can cause intracranial hypertension may increase the risk. (label Tretinoin, Peringatan dan perhatian)

  • Doksisiklinantibiotik tetrasiklinModerat

    The concomitant use of other products (e.g., tetracyclines) that can cause intracranial hypertension may increase the risk. (label Tretinoin, Peringatan dan perhatian)

  • Patients with elevated vitamin A levels may be at increased risk. (label Eleksakaftor, tezakaftor, dan ivakaftor, Peringatan dan perhatian)

  • Drugs That Increase the Risk of Hypercalcemia Increase frequency of monitoring of calcium concentrations in patients taking concomitant Calcium Chloride Injection and other drugs that increase the risk of hypercalcemia (e.g., calcipotriene, estrogen, lithium, parathyroid hormone, teriparatide, thiazide diuretics, Vitamin A, and Vitamin D). (label Kalsium klorida, Interaksi obat)

  • MetotreksatimunosupresanModerat

    Monitor patients receiving XATMEP with other potential hepatotoxins (e.g., azathioprine, retinoids, and sulfasalazine) for possible signs of hepatotoxicity. (label Metotreksat, Interaksi obat)

  • OrlistatModerat

    The effect of ORLISTAT on the absorption of supplemental vitamin D, vitamin A, and nutritionally-derived vitamin K is not known at this time [see Clinical Pharmacology (12.3) , and Warnings and Precautions (5.1) ] . (label Orlistat, Interaksi obat)

  • Tigesiklinantibiotik tetrasiklinModerat

    The concomitant use of other products (e.g., tetracyclines) that can cause intracranial hypertension may increase the risk. (label Tretinoin, Peringatan dan perhatian)

Penyebutan minor (1)

  • Drugs that may cause hypercalcemia: Vitamin D, vitamin A, thiazide diuretics, estrogen, calcipotriene and teriparatide administration may cause hypercalcemia. (label Kalsium glukonat, Interaksi obat)

Periksa Tretinoin terhadap semua yang Anda gunakan. Tambahkan seluruh daftar Anda; setiap pasangan diperiksa sekaligus.

Buka di pemeriksa

Bukan nasihat medis. Tingkat keparahan mencerminkan kata-kata dalam label, bukan keadaan Anda. Tanda “mayor” bisa merupakan hal yang rutin di bawah pengawasan, dan tanda “minor” bisa menjadi penting pada dosis tinggi. Tanyakan kepada apoteker.