Interaction Checker

Interaksi Trilasiklib

Trilasiklib (Cosela) memiliki 8 interaksi terdokumentasi dalam label FDA dan lembar fakta yang kami indeks: 1 mayor, 2 moderat, 5 minor, dan 0 dengan label yang melaporkan tidak ada interaksi bermakna. Setiap entri di bawah ini mengutip kalimat yang mendasarinya. Halaman obat ini adalah titik awal, bukan putusan untuk situasi Anda.

Interaksi dari label

Interaksi mayor (1)

  • DofetilidantiaritmiaMayor

    Increased plasma concentrations of dofetilide may cause serious ventricular arrhythmias associated with QT interval prolongation, including torsade de pointes. (label Trilasiklib, Interaksi obat)

Interaksi moderat (2)

  • Dalfampridinsuplemen kaliumModerat

    Co-administration of COSELA may increase the concentration or net accumulation of OCT2, MATE1, and MATE-2K substrates in the kidney (e.g., dofetilide, dalfampridine, and cisplatin) [see Clinical Pharmacology ( 12.3 )]. (label Trilasiklib, Interaksi obat)

  • SisplatinModerat

    Co-administration of COSELA may increase the concentration or net accumulation of OCT2, MATE1, and MATE-2K substrates in the kidney (e.g., dofetilide, dalfampridine, and cisplatin) [see Clinical Pharmacology ( 12.3 )]. (label Trilasiklib, Interaksi obat)

Penyebutan minor (5)

  • Artikain dan epinefrinanestetik lokalMinor

    One patient experienced a Grade 2 anaphylactic reaction 4 days after receiving COSELA, which resolved with epinephrine, and treatment with COSELA was continued. (label Trilasiklib, Peringatan dan perhatian)

  • Bupivakain dan epinefrinanestetik lokalMinor

    One patient experienced a Grade 2 anaphylactic reaction 4 days after receiving COSELA, which resolved with epinephrine, and treatment with COSELA was continued. (label Trilasiklib, Peringatan dan perhatian)

  • EpinefrinsimpatomimetikMinor

    One patient experienced a Grade 2 anaphylactic reaction 4 days after receiving COSELA, which resolved with epinephrine, and treatment with COSELA was continued. (label Trilasiklib, Peringatan dan perhatian)

  • Lidokain dan epinefrinanestetik lokalMinor

    One patient experienced a Grade 2 anaphylactic reaction 4 days after receiving COSELA, which resolved with epinephrine, and treatment with COSELA was continued. (label Trilasiklib, Peringatan dan perhatian)

  • Prilokain dan epinefrinanestetik lokalMinor

    One patient experienced a Grade 2 anaphylactic reaction 4 days after receiving COSELA, which resolved with epinephrine, and treatment with COSELA was continued. (label Trilasiklib, Peringatan dan perhatian)

Periksa Trilasiklib terhadap semua yang Anda gunakan. Tambahkan seluruh daftar Anda; setiap pasangan diperiksa sekaligus.

Buka di pemeriksa

Bukan nasihat medis. Tingkat keparahan mencerminkan kata-kata dalam label, bukan keadaan Anda. Tanda “mayor” bisa merupakan hal yang rutin di bawah pengawasan, dan tanda “minor” bisa menjadi penting pada dosis tinggi. Tanyakan kepada apoteker.