Interaksi Asam zoledronat

Asam zoledronat (Reclast, Zometa), golongan bisfosfonat, memiliki 113 interaksi terdokumentasi dalam label FDA dan lembar fakta yang kami indeks: 1 mayor, 102 moderat, 10 minor, dan 0 dengan label yang melaporkan tidak ada interaksi bermakna. Setiap entri di bawah ini mengutip kalimat yang mendasarinya. Halaman obat ini adalah titik awal, bukan putusan untuk situasi Anda.

Interaksi dari label

Interaksi mayor (1)

  • PamidronatbisfosfonatMayor

    Pamidronate disodium is contraindicated in patients with hypersensitivity to pamidronate disodium, other bisphosphonates, or mannitol. (label Pamidronat, Kontraindikasi)

Interaksi moderat (102)

  • AmikasinaminoglikosidaModerat

    • Aminoglycosides: May lower serum calcium for prolonged periods ( 7.1 ) (label Asam zoledronat, Interaksi obat)

  • Amiloriddiuretik hemat kaliumModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Asam etakrinatdiuretik loopModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Asam mefenamatOAINSModerat

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • Asetazolamidpenghambat karbonat anhidraseModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • AspirinOAINSModerat

    Use Reclast with caution in aspirin-sensitive patients. (label Asam zoledronat, Peringatan dan perhatian)

  • Aspirin dan dipiridamolantiplateletModerat

    Use Reclast with caution in aspirin-sensitive patients. (label Asam zoledronat, Peringatan dan perhatian)

  • Atenolol dan klortalidonpenyekat betaModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Azelastin dan flutikasonantihistaminModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • BeklometasonkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • Benazepril dan hidroklorotiazidpenghambat ACEModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • BetametasonkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • BudesonidkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • Budesonid dan formoterolkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • Bumetaniddiuretik loopModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Use Reclast with caution in aspirin-sensitive patients. (label Asam zoledronat, Peringatan dan perhatian)

  • Use Reclast with caution in aspirin-sensitive patients. (label Asam zoledronat, Peringatan dan perhatian)

  • Deferasirokssuplemen zat besiModerat

    The risk of GI hemorrhage may be increased when administering Exjade in combination with drugs that have ulcerogenic or hemorrhagic potential, such as nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, oral bisphosphonates, or anticoagulants. (label Deferasiroks, Peringatan dan perhatian)

  • DeflazakortkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • DeksametasonkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • DesonidkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • DiflunisalOAINSModerat

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • Digoksinglikosida digitalisModerat

    In patients with renal impairment, the exposure to concomitant medications that are primarily renally excreted (e.g., digoxin) may increase. (label Asam zoledronat, Interaksi obat)

  • DiklofenakOAINSModerat

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • Dokserkalsiferolanalog vitamin DModerat

    All patients should be instructed about the symptoms of hypocalcemia and the importance of calcium and vitamin D supplementation in maintaining serum calcium levels [see Dosage and Administration ( 2.8 ), Adverse Reactions ( 6.1 ), Patient Counseling Information ( 17 )]. (label Asam zoledronat, Peringatan dan perhatian)

  • Enalapril dan hidroklorotiazidpenghambat ACEModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Eplerenonantagonis aldosteronModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • EtodolakOAINSModerat

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • FenoprofenOAINSModerat

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • FludrokortisonkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • FlunisolidkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • FluosinonidkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • FlurbiprofenOAINSModerat

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • FlutikasonkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • Flutikason dan salmeterolkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • Fosinopril dan hidroklorotiazidpenghambat ACEModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Furosemiddiuretik loopModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • GentamisinaminoglikosidaModerat

    • Aminoglycosides: May lower serum calcium for prolonged periods ( 7.1 ) (label Asam zoledronat, Interaksi obat)

  • HalobetasolkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • Hidroklorotiaziddiuretik tiazidModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • HidrokortisonkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • IbuprofenOAINSModerat

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • Indapamiddiuretik tiazidModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • IndometasinOAINSModerat

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • Irbesartan dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Moderat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Kalsipotriolanalog vitamin DModerat

    All patients should be instructed about the symptoms of hypocalcemia and the importance of calcium and vitamin D supplementation in maintaining serum calcium levels [see Dosage and Administration ( 2.8 ), Adverse Reactions ( 6.1 ), Patient Counseling Information ( 17 )]. (label Asam zoledronat, Peringatan dan perhatian)

  • Kalsitriolanalog vitamin DModerat

    All patients should be instructed about the symptoms of hypocalcemia and the importance of calcium and vitamin D supplementation in maintaining serum calcium levels [see Dosage and Administration ( 2.8 ), Adverse Reactions ( 6.1 ), Patient Counseling Information ( 17 )]. (label Asam zoledronat, Peringatan dan perhatian)

  • KalsiumVitamin dan mineralModerat

    Kalsium mengikat obat-obat ini di usus dan dapat sangat mengurangi jumlah yang diserap; pisahkan waktu minum dosisnya. (NIH Office of Dietary Supplements, Calcium)

  • Kandesartan dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Moderat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • KapesitabinantimetabolitModerat

    Closely monitor for signs of renal toxicity when XELODA is used concomitantly with nephrotoxic drugs (e.g. platinum salts, irinotecan, methotrexate, intravenous bisphosphonates). (label Kapesitabin, Interaksi obat)

  • KetoprofenOAINSModerat

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • KetorolakOAINSModerat

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • KlobetasolkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • Klorotiaziddiuretik tiazidModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Klortalidondiuretik tiazidModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Kuinapril dan hidroklorotiazidpenghambat ACEModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Lisinopril dan hidroklorotiazidpenghambat ACEModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Losartan dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Moderat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • MagnesiumVitamin dan mineralModerat

    Suplemen dan antasida yang mengandung magnesium mengurangi penyerapan obat-obat ini; pisahkan dosisnya dengan jarak setidaknya dua jam. (NIH Office of Dietary Supplements, Magnesium)

  • MeloksikamOAINSModerat

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • MetilprednisolonkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • Metolazondiuretik tiazidModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • MometasonkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • NabumetonOAINSModerat

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • NaproksenOAINSModerat

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • NeomisinaminoglikosidaModerat

    • Aminoglycosides: May lower serum calcium for prolonged periods ( 7.1 ) (label Asam zoledronat, Interaksi obat)

  • OksaprozinOAINSModerat

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • OksibutininantikolinergikModerat

    Oxybutynin chloride extended-release tablets should be used with caution in patients who have gastroesophageal reflux and/or who are concurrently taking drugs (such as bisphosphonates) that can cause or exacerbate esophagitis. (label Oksibutinin, Peringatan dan perhatian)

  • Olmesartan dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Moderat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Olmesartan, amlodipin, dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Moderat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Olopatadin dan mometasonantihistaminModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • Use Reclast with caution in aspirin-sensitive patients. (label Asam zoledronat, Peringatan dan perhatian)

  • Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • Parikalsitolanalog vitamin DModerat

    All patients should be instructed about the symptoms of hypocalcemia and the importance of calcium and vitamin D supplementation in maintaining serum calcium levels [see Dosage and Administration ( 2.8 ), Adverse Reactions ( 6.1 ), Patient Counseling Information ( 17 )]. (label Asam zoledronat, Peringatan dan perhatian)

  • PiroksikamOAINSModerat

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • PlazomisinaminoglikosidaModerat

    • Aminoglycosides: May lower serum calcium for prolonged periods ( 7.1 ) (label Asam zoledronat, Interaksi obat)

  • PrednisolonkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • PrednisonkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • SalsalatOAINSModerat

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • SelekoksibOAINSModerat

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • SiklesonidkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • Spironolaktonantagonis aldosteronModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Spironolakton dan hidroklorotiazidantagonis aldosteronModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • SulindakOAINSModerat

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • SunitinibModerat

    Concomitant exposure to other risk factors, such as bisphosphonates or dental disease/invasive dental procedures, may increase the risk of ONJ. (label Sunitinib, Peringatan dan perhatian)

  • Telmisartan dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Moderat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • TobramisinaminoglikosidaModerat

    • Aminoglycosides: May lower serum calcium for prolonged periods ( 7.1 ) (label Asam zoledronat, Interaksi obat)

  • TolmetinOAINSModerat

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (label Asam zoledronat, Interaksi obat)

  • Torasemiddiuretik loopModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • TriamsinolonkortikosteroidModerat

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (label Asam zoledronat, Peringatan dan perhatian)

  • Triamterendiuretik hemat kaliumModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Triamteren dan hidroklorotiaziddiuretik hemat kaliumModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Valsartan dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Moderat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Vitamin DVitamin dan mineralModerat

    All patients should be instructed about the symptoms of hypocalcemia and the importance of calcium and vitamin D supplementation in maintaining serum calcium levels [see Dosage and Administration ( 2.8 ), Adverse Reactions ( 6.1 ), Patient Counseling Information ( 17 )]. (label Asam zoledronat, Peringatan dan perhatian)

  • Zat besiVitamin dan mineralModerat

    Zat besi mengikat obat-obat ini di usus dan mengurangi penyerapannya; pisahkan waktu minum dosisnya. (NIH Office of Dietary Supplements, Iron)

Penyebutan minor (10)

  • AlendronatbisfosfonatMinor

    A subset had recurrence of symptoms when rechallenged with the same drug or another bisphosphonate [see Adverse Reactions ( 6.2 )] . (label Asam zoledronat, Peringatan dan perhatian)

  • Eksemestanpenghambat aromataseMinor

    Concomitant use of bisphosphonates, vitamin D supplementation, and calcium was not allowed. (label Eksemestan, Peringatan dan perhatian)

  • IbandronatbisfosfonatMinor

    A subset had recurrence of symptoms when rechallenged with the same drug or another bisphosphonate [see Adverse Reactions ( 6.2 )] . (label Asam zoledronat, Peringatan dan perhatian)

  • Levotiroksinhormon tiroidMinor

    Hypocalcemia and Mineral Metabolism Preexisting hypocalcemia and disturbances of mineral metabolism (e.g., hypoparathyroidism, thyroid surgery, parathyroid surgery; malabsorption syndromes, excision of small intestine) must be effectively treated before initiating therapy with Reclast. (label Asam zoledronat, Peringatan dan perhatian)

  • Levotiroksin dan liotironinhormon tiroidMinor

    Hypocalcemia and Mineral Metabolism Preexisting hypocalcemia and disturbances of mineral metabolism (e.g., hypoparathyroidism, thyroid surgery, parathyroid surgery; malabsorption syndromes, excision of small intestine) must be effectively treated before initiating therapy with Reclast. (label Asam zoledronat, Peringatan dan perhatian)

  • Liotironinhormon tiroidMinor

    Hypocalcemia and Mineral Metabolism Preexisting hypocalcemia and disturbances of mineral metabolism (e.g., hypoparathyroidism, thyroid surgery, parathyroid surgery; malabsorption syndromes, excision of small intestine) must be effectively treated before initiating therapy with Reclast. (label Asam zoledronat, Peringatan dan perhatian)

  • Propiltiourasilobat antitiroidMinor

    Hypocalcemia and Mineral Metabolism Preexisting hypocalcemia and disturbances of mineral metabolism (e.g., hypoparathyroidism, thyroid surgery, parathyroid surgery; malabsorption syndromes, excision of small intestine) must be effectively treated before initiating therapy with Reclast. (label Asam zoledronat, Peringatan dan perhatian)

  • RisedronatbisfosfonatMinor

    A subset had recurrence of symptoms when rechallenged with the same drug or another bisphosphonate [see Adverse Reactions ( 6.2 )] . (label Asam zoledronat, Peringatan dan perhatian)

  • Teriparatidhormon tiroidMinor

    Hypocalcemia and Mineral Metabolism Preexisting hypocalcemia and disturbances of mineral metabolism (e.g., hypoparathyroidism, thyroid surgery, parathyroid surgery; malabsorption syndromes, excision of small intestine) must be effectively treated before initiating therapy with Reclast. (label Asam zoledronat, Peringatan dan perhatian)

  • Tiamazolobat antitiroidMinor

    Hypocalcemia and Mineral Metabolism Preexisting hypocalcemia and disturbances of mineral metabolism (e.g., hypoparathyroidism, thyroid surgery, parathyroid surgery; malabsorption syndromes, excision of small intestine) must be effectively treated before initiating therapy with Reclast. (label Asam zoledronat, Peringatan dan perhatian)

Periksa Asam zoledronat terhadap semua yang Anda gunakan. Tambahkan seluruh daftar Anda; setiap pasangan diperiksa sekaligus.

Buka di pemeriksa

Bukan nasihat medis. Tingkat keparahan mencerminkan kata-kata dalam label, bukan keadaan Anda. Tanda “mayor” bisa merupakan hal yang rutin di bawah pengawasan, dan tanda “minor” bisa menjadi penting pada dosis tinggi. Tanyakan kepada apoteker.