Interaksi Butalbital, aspirin, kafein, dan kodein dan Trazodon

Butalbital, aspirin, kafein, dan kodein dan Trazodon: kedua label peresepan menandai kombinasi ini dengan bahasa yang paling tegas, seperti kontraindikasi, peringatan kotak hitam, atau instruksi untuk menghindarinya.

Mayor

Jangan dikombinasikan tanpa arahan dokter yang meresepkan. Bahasa label di bawah ini adalah yang paling tegas yang digunakan FDA.

Apa kata label FDA

Dari label Butalbital, aspirin, kafein, dan kodein (BUTALBITAL, ASPIRIN, CAFFEINE and CODEINE PHOSPHATE) · berlaku sejak 2026-01-15

Mayor

Concomitant use of opioids or a barbiturate with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death.

Peringatan kotak hitamberdasarkan golongan obatLihat label di DailyMed
Mayor

Risks From Concomitant Use With Benzodiazepines Or Other CNS Depressants Concomitant use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death.

Peringatan kotak hitamberdasarkan golongan obatLihat label di DailyMed
Mayor

Reserve concomitant prescribing of BUTALBITAL, ASPIRIN, CAFFEINE and CODEINE PHOSPHATE and benzodiazepines or other CNS depressants for use in patients for whom alternative treatment options are inadequate. [see Warnings and Precautions ( 5.3 , 5.9 ), Drug Interactions ( 7 )].

Peringatan kotak hitamberdasarkan golongan obatLihat label di DailyMed
Mayor

Risks from Concomitant Use with Benzodiazepines or Other CNS Depressants Profound sedation, respiratory depression, coma, and death may result from the concomitant use of BUTALBITAL, ASPIRIN, CAFFEINE and CODEINE PHOSPHATE with benzodiazepines and/or other CNS depressants, including alcohol (e.g., non-benzodiazepine sedatives/hypnotics, anxiolytics, tranquilizers,…

Peringatan dan perhatianberdasarkan golongan obatLihat label di DailyMed
Mayor

Screen patients for risk of substance use disorders, including opioid abuse and misuse, and warn them of the risk for overdose and death associated with the use of additional CNS depressants including alcohol and illicit drugs [see Drug Interactions ( 7 ) and Patient Counseling Information ( 17 ) ].

Peringatan dan perhatianberdasarkan golongan obatLihat label di DailyMed

Dari label Trazodon (RALDESY TM) · berlaku sejak 2026-09-01

Moderat

Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.5 ).

Peringatan dan perhatianberdasarkan golongan obatLihat label di DailyMed
Moderat

Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDS), other antiplatelet drugs, warfarin, and other anticoagulants may add to this risk.

Peringatan dan perhatianberdasarkan golongan obatLihat label di DailyMed
Moderat

Inform patients about the risk of bleeding associated with the concomitant use of RALDESY and antiplatelet agents or anticoagulants.

Peringatan dan perhatianberdasarkan golongan obatLihat label di DailyMed
Moderat

CNS Depressants: RALDESY may enhance effects of alcohol, barbiturates, or other CNS depressants ( 7 ).

Interaksi obatberdasarkan golongan obatLihat label di DailyMed
Moderat

The concurrent use of an antiplatelet agent or anticoagulant with RALDESY may potentiate the risk of bleeding.

Interaksi obatberdasarkan golongan obatLihat label di DailyMed

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