Acamprosate and Alcohol interaction
Acamprosate and Alcohol: the Acamprosate prescribing label mentions this combination without an instruction to avoid it or change the dose.
Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.
What the FDA labels say
From the Acamprosate (ACAMPROSATE CALCIUM) label · effective 2026-07-14
Alcohol Withdrawal Use of acamprosate calcium does not eliminate or diminish withdrawal symptoms.
Acamprosate does not affect the pharmacokinetics of alcohol.
The pharmacokinetics of acamprosate are not affected by alcohol, diazepam, or disulfiram, and clinically important interactions between naltrexone and acamprosate were not observed [ see Clinical Pharmacology ( 12.3 ) ].
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.