Acamprosate and Methylnaltrexone interaction

Acamprosate and Methylnaltrexone: the Acamprosate prescribing label reports no clinically significant interaction between these two.

No interaction

No clinically significant interaction reported. The label studied or considered this pair and found nothing meaningful.

What the FDA labels say

From the Acamprosate (ACAMPROSATE CALCIUM) label · effective 2026-07-14

No interaction

The pharmacokinetics of acamprosate are not affected by alcohol, diazepam, or disulfiram, and clinically important interactions between naltrexone and acamprosate were not observed [ see Clinical Pharmacology ( 12.3 ) ].

Drug interactionsby drug classView label on DailyMed

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Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.