Antacids (Tums, Maalox, Mylanta) and Lanthanum interaction

Antacids (Tums, Maalox, Mylanta) and Lanthanum: the Lanthanum prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Lanthanum (Lanthanum carbonate) label · effective 2025-12-15

Major

There is a potential for LANTHANUM CARBONATE to interact with compounds that bind to cationic antacids (i.e., aluminum-, magnesium-, or calcium-based); therefore, do not take such compounds within 2 hours of dosing with LANTHANUM CARBONATE.

Drug interactionsnames Antacids (Tums, Maalox, Mylanta)View label on DailyMed
Major

Drugs Binding to Antacids There is a potential for LANTHANUM CARBONATE to interact with compounds which bind to cationic antacids (i.e., aluminum-, magnesium-, or calcium-based); therefore, do not administer such compounds within 2 hours of dosing with LANTHANUM CARBONATE.

Drug interactionsnames Antacids (Tums, Maalox, Mylanta)View label on DailyMed
Moderate

Examples of relevant classes of compounds where antacids have been demonstrated to reduce bioavailability include antibiotics (such as quinolones, ampicillin, and tetracyclines), thyroid hormones, ACE inhibitors, statin lipid regulators, and anti-malarials.

Drug interactionsnames Antacids (Tums, Maalox, Mylanta)View label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.