Ciprofloxacin and Lanthanum interaction
Ciprofloxacin and Lanthanum: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Ciprofloxacin label · effective 2026-06-30
…Ciprofloxacin Antacids, Sucralfate, Multivitamins and Other Products Containing Multivalent Cations (magnesium/aluminum antacids; polymeric phosphate binders (for example, sevelamer, lanthanum carbonate); sucralfate; Videx ® (didanosine) chewable/buffered tablets or pediatric powder; other highly buffered drugs; or products containing calcium, iron, or zinc and…
From the Lanthanum (Lanthanum carbonate) label · effective 2025-12-15
The bioavailability of oral ciprofloxacin was decreased by approximately 50% when taken with LANTHANUM CARBONATE in a single-dose study in healthy volunteers.
Examples of relevant classes of compounds where antacids have been demonstrated to reduce bioavailability include antibiotics (such as quinolones, ampicillin, and tetracyclines), thyroid hormones, ACE inhibitors, statin lipid regulators, and anti-malarials.
Quinolone Antibiotics Co-administration of LANTHANUM CARBONATE with quinolone antibiotics may reduce the extent of their absorption.
When oral quinolones are given for short courses, consider eliminating the doses of LANTHANUM CARBONATE that would normally be scheduled near the time of quinolone intake to improve quinolone absorption [see Clinical Pharmacology (12.3) ] .
Oral quinolone antibiotics must be taken at least 1 hour before or 4 hours after LANTHANUM CARBONATE.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.