Aspirin and Menthol and methyl salicylate interaction

Aspirin and Menthol and methyl salicylate: the Menthol and methyl salicylate prescribing label flag this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Menthol and methyl salicylate (Icy Hot Pain Relieving Balm) label · effective 2026-06-12

Major

Warnings For external use only Allergy alert: do not use if you are allergic to salicylates (including aspirin) unless directed by a doctor.

Warningsnames AspirinView label on DailyMed
Minor

Warnings For external use only SEE INSIDE LABEL FOR COMPLETE DRUG FACTS Allergy Alert: If prone to allergic reaction from aspirin or salicylates, consult a doctor before use.

Warningsnames AspirinView label on DailyMed
Minor

Warnings For external use only Allergy alert: if prone to allergic reaction from aspirin or salicylates, consult a doctor before use When using this product ■ use only as directed.

Warningsnames AspirinView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.