Atorvastatin and Digoxin interaction

Atorvastatin and Digoxin: the Atorvastatin prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Atorvastatin (Lipitor) label · effective 2024-04-15

Moderate

Digoxin: May increase digoxin plasma levels; monitor patients appropriately ( 7.3 ).

Drug interactionsnames DigoxinView label on DailyMed
Moderate

Digoxin Clinical Impact: When multiple doses of LIPITOR and digoxin were co-administered, steady state plasma digoxin concentrations increased [see Clinical Pharmacology (12.3) ].

Drug interactionsnames DigoxinView label on DailyMed
Moderate

Intervention: Monitor patients taking digoxin appropriately.

Drug interactionsnames DigoxinView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.