Chlorpheniramine and Temsirolimus interaction
Chlorpheniramine and Temsirolimus: the Temsirolimus prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Temsirolimus (Torisel) label · effective 2025-12-26
TORISEL should be used with caution in patients with known hypersensitivity to an antihistamine, or patients who cannot receive an antihistamine for other medical reasons.
• To treat hypersensitivity reactions, stop TORISEL and treat with an antihistamine.
An H 1 antihistamine should be administered to patients before the start of the intravenous temsirolimus infusion.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.