Cholestyramine and Leflunomide interaction
Cholestyramine and Leflunomide: the Leflunomide prescribing label mentions this combination without an instruction to avoid it or change the dose.
Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.
What the FDA labels say
From the Leflunomide (Arava) label · effective 2025-06-04
Elimination can be accelerated by the following procedures: Administer cholestyramine 8 grams orally 3 times daily for 11 days.
If plasma teriflunomide concentrations are higher than 0.02 mg/L, repeat cholestyramine and/or activated charcoal treatment.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.