Conjugated estrogens and bazedoxifene and Tobacco and smoking interaction

Conjugated estrogens and bazedoxifene and Tobacco and smoking: the Conjugated estrogens and bazedoxifene prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Conjugated estrogens and bazedoxifene (Duavee) label · effective 2026-07-31

Moderate

Risk factors for arterial vascular disease (for example, hypertension, diabetes mellitus, tobacco use, hypercholesterolemia, and obesity) and/or VTE (for example, personal history or family history of VTE, obesity, and systemic lupus erythematosus) should be managed appropriately.

Warnings and precautionsnames Tobacco and smokingView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.