Lidocaine and Raloxifene interaction

Lidocaine and Raloxifene: the Raloxifene prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Raloxifene (Evista) label · effective 2026-02-11

Moderate

Other Highly Protein-Bound Drugs EVISTA should be used with caution with certain other highly protein-bound drugs such as diazepam, diazoxide, and lidocaine.

Drug interactionsnames LidocaineView label on DailyMed
Minor

Highly protein-bound drugs include diazepam, diazoxide, and lidocaine.

Drug interactionsnames LidocaineView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.