Naltrexone and bupropion and Tobacco and smoking interaction

Naltrexone and bupropion and Tobacco and smoking: the Naltrexone and bupropion prescribing label mentions this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Naltrexone and bupropion (Contrave Extended-Release) label · effective 2025-11-10

Minor

Some patients who stopped smoking may have been experiencing symptoms of nicotine withdrawal, including depressed mood.

Warnings and precautionsnames Tobacco and smokingView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.