Interações de Acetazolamida

Acetazolamida (Diamox), inibidor da anidrase carbônica, tem 348 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 60; moderadas: 255; leves: 30; casos em que uma bula relata não haver interação significativa: 3). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.

Aparência de Acetazolamida

Todas as 30 versões
Acetazolamida 125 mg em comprimido: branco, redondo, 9 mm, sulcado, com a gravação 1238.
1238
125 mg · branco · redondo · 9 mm · sulcado
Zydus Pharmaceuticals (USA)
Acetazolamida 250 mg em comprimido: branco, redondo, 11 mm, com a gravação 1239.
1239
250 mg · branco · redondo · 11 mm
Zydus Pharmaceuticals (USA)
Acetazolamida 500 mg em cápsula: laranja, 24 mm, com a gravação A de um lado e 247 do outro.
A / 247
500 mg · laranja · cápsula · 24 mm
Alembic
Acetazolamida 500 mg em cápsula: amarelo e branco, 26 mm, com a gravação XYL de um lado e 34 do outro.
XYL / 34
500 mg · amarelo e branco · cápsula · 26 mm
Zydus Pharmaceuticals (USA)

Representações criadas a partir das listas de produtos das bulas da FDA: cor, formato, tamanho e gravação. 30 versões documentadas de 21 fabricantes.

Interações segundo a bula

Interações graves (60)

  • Caution is advised for patients receiving concomitant high-dose aspirin and acetazolamide, as anorexia, tachypnea, lethargy, metabolic acidosis, coma, and death have been reported. (bula de Acetazolamida, Advertências)

  • Ácido acetilsalicílico + dipiridamolantiagregante plaquetárioGrave

    Caution is advised for patients receiving concomitant high-dose aspirin and acetazolamide, as anorexia, tachypnea, lethargy, metabolic acidosis, coma, and death have been reported. (bula de Acetazolamida, Advertências)

  • Ácido etacrínicodiurético de alçaGrave

    Like other diuretics it may precipitate hepatic coma and death. (bula de Ácido etacrínico, Advertências)

  • Because the use of diuretics can accentuate the diminished intravascular volume, avoid diuretics except in the late phase of resolution. (bula de Alfacoriogonadotropina, Advertências)

  • Alogliptina + metforminainibidor da DPP-4Grave

    Risk factors for metformin-associated lactic acidosis include renal impairment, concomitant use of certain drugs (e.g., carbonic anhydrase inhibitors such as topiramate), age 65 years old or greater, having a radiological study with contrast, surgery and other procedures, hypoxic states (e.g., acute congestive heart failure), excessive alcohol intake, hepatic… (bula de Alogliptina + metformina, Advertência em caixa preta)

  • Atenolol + clortalidonabetabloqueadorGrave

    CONTRAINDICATIONS Atenolol and chlorthalidone is contraindicated in patients with: sinus bradycardia; heart block greater than first degree; cardiogenic shock; overt cardiac failure (See WARNINGS ); anuria; hypersensitivity to this product or to sulfonamide-derived drugs. (bula de Atenolol + clortalidona, Contraindicações)

  • Benazepril + hidroclorotiazidainibidor da ECAGrave

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (bula de Benazepril + hidroclorotiazida, Contraindicações)

  • Bicarbonato de sódioantiácidoGrave

    Sodium bicarbonate injection is contraindicated in patients who are losing chloride by vomiting or from continuous gastrointestinal suction and in patients receiving diuretics known to produce a hypochloremic alkalosis. (bula de Bicarbonato de sódio, Contraindicações)

  • CONTRAINDICATIONS Bisoprolol fumarate and hydrochlorothiazide tablets are contraindicated in patients in cardiogenic shock, overt cardiac failure (see WARNINGS ), second or third degree AV block, marked sinus bradycardia, anuria, and hypersensitivity to either component of this product or to other sulfonamide-derived drugs. (bula de Bisoprolol + hidroclorotiazida, Contraindicações)

  • Caution is advised for patients receiving concomitant high-dose aspirin and acetazolamide, as anorexia, tachypnea, lethargy, metabolic acidosis, coma, and death have been reported. (bula de Acetazolamida, Advertências)

  • Caution is advised for patients receiving concomitant high-dose aspirin and acetazolamide, as anorexia, tachypnea, lethargy, metabolic acidosis, coma, and death have been reported. (bula de Acetazolamida, Advertências)

  • Candesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Grave

    CONTRAINDICATIONS Candesartan cilexetil and hydrochlorothiazide tablets are contraindicated in patients who are hypersensitive to candesartan, to hydrochlorothiazide or to other sulfonamide-derived drugs. (bula de Candesartana + hidroclorotiazida, Contraindicações)

  • CelecoxibeAINEGrave

    • In patients who have demonstrated allergic-type reactions to sulfonamides [ see Warnings and Precautions (5.7) ]. (bula de Celecoxibe, Contraindicações)

  • CiclosporinaimunossupressorGrave

    Potassium-Sparing Diuretics Cyclosporine should not be used with potassium-sparing diuretics because hyperkalemia can occur. (bula de Ciclosporina, Interações medicamentosas)

  • CidofovirantiviralGrave

    Cidofovir injection is contraindicated in patients with a history of clinically severe hypersensitivity to probenecid or other sulfa-containing medications. (bula de Cidofovir, Contraindicações)

  • Citrato de potássiosuplemento de potássioGrave

    The following drug interactions may occur with potassium citrate: Potassium-sparing diuretics: concomitant administration should be avoided since the simultaneous administration of these agents can produce severe hyperkalemia (7.1) (bula de Citrato de potássio, Interações medicamentosas)

  • Cloroprocaínaanestésico localGrave

    Therefore, chloroprocaine should not be used in any condition in which a sulfonamide drug is being employed. (bula de Cloroprocaína, Precauções)

  • Clorotiazidadiurético tiazídicoGrave

    Hypersensitivity to this product or to other sulfonamide-derived drugs. (bula de Clorotiazida, Contraindicações)

  • Clortalidonadiurético tiazídicoGrave

    THALITONE is contraindicated in patients with anuria or hypersensitivity to chlorthalidone or other sulfonamide-derived drugs. (bula de Clortalidona, Contraindicações)

  • Dapagliflozina + metforminainibidor do SGLT2Grave

    • Risk factors for metformin-associated lactic acidosis include renal impairment, concomitant use of certain drugs (e.g., carbonic anhydrase inhibitors such as topiramate), age 65 years old or greater, having a radiological study with contrast, surgery and other procedures, hypoxic states (e.g., acute congestive heart failure), excessive alcohol intake, hepatic… (bula de Dapagliflozina + metformina, Advertência em caixa preta)

  • Diclorfenamidainibidor da anidrase carbônicaGrave

    KEVEYIS is contraindicated in the following circumstances: Hypersensitivity to dichlorphenamide or other sulfonamides [see Warnings and Precautions (5.1) ] Concomitant use of KEVEYIS and high dose aspirin [see Warnings and Precautions (5.2) and Drug Interactions (7.1) ] Severe pulmonary disease, limiting compensation to metabolic acidosis caused by KEVEYIS [see… (bula de Diclorfenamida, Contraindicações)

  • DofetilidaantiarrítmicoGrave

    In the DIAMOND trials, 1252 patients were treated with dofetilide and diuretics concomitantly, of whom 493 died compared to 508 deaths among the 1248 patients receiving placebo and diuretics. (bula de Dofetilida, Interações medicamentosas)

  • Droperidolantagonista da dopaminaGrave

    Droperidol should be administered with extreme caution to patients who may be at risk for development of prolonged QT syndrome (e.g., congestive heart failure, bradycardia, use of a diuretic, cardiac hypertrophy, hypokalemia, hypomagnesemia, or administration of other drugs known to increase the QT interval). (bula de Droperidol, Advertência em caixa preta)

  • Dutasterida + tansulosinainibidor da 5-alfa-redutaseGrave

    If a patient reports a serious or life-threatening sulfa allergy, caution is warranted when administering tamsulosin-containing products, including JALYN. (bula de Dutasterida + tansulosina, Advertências e precauções)

  • Empagliflozina + metforminainibidor do SGLT2Grave

    Risk factors for metformin-associated lactic acidosis include renal impairment, concomitant use of certain drugs (e.g., carbonic anhydrase inhibitors such as topiramate), age 65 years old or greater, having a radiological study with contrast, surgery and other procedures, hypoxic states (e.g., acute congestive heart failure), excessive alcohol intake, hepatic… (bula de Empagliflozina + metformina, Advertência em caixa preta)

  • Enalapril + hidroclorotiazidainibidor da ECAGrave

    Because of the hydrochlorothiazide component, this product is contraindicated in patients with anuria or hypersensitivity to other sulfonamide-derived drugs. (bula de Enalapril + hidroclorotiazida, Contraindicações)

  • Enalaprilateinibidor da ECAGrave

    …sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include those with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (bula de Enalaprilate, Advertências)

  • Espironolactona + hidroclorotiazidaantagonista da aldosteronaGrave

    CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (bula de Espironolactona + hidroclorotiazida, Contraindicações)

  • Fentermina + topiramatoestimulante do SNCGrave

    Avoid use of phentermine and topiramate extended-release capsules with other carbonic anhydrase inhibitors. (bula de Fentermina + topiramato, Advertências e precauções)

  • Because the use of diuretics can accentuate the diminished intravascular volume, diuretics should be avoided except in the late phase of resolution as described below. (bula de Folitropina, Advertências e precauções)

  • Fosinopril + hidroclorotiazidainibidor da ECAGrave

    Fosinopril sodium and hydrochlorothiazide is also contraindicated in patients who are hypersensitive to fosinopril, to any other ACE inhibitor, to hydrochlorothiazide, or other sulfonamide-derived drugs, or any other ingredient or component in the formulation. (bula de Fosinopril + hidroclorotiazida, Contraindicações)

  • GentamicinaaminoglicosídeoGrave

    The concurrent use of gentamicin with potent diuretics, such as ethacrynic acid or furosemide, should be avoided, since certain diuretics by themselves may cause ototoxicity. (bula de Gentamicina, Advertência em caixa preta)

  • Glibenclamida + metforminasulfonilureiaGrave

    Risk factors for metformin-associated lactic acidosis include renal impairment, concomitant use of certain drugs (e.g., carbonic anhydrase inhibitors such as topiramate), age 65 years old or greater, having a radiological study with contrast, surgery and other procedures, hypoxic states (e.g. , acute congestive heart failure), excessive alcohol intake, hepatic… (bula de Glibenclamida + metformina, Advertência em caixa preta)

  • GlimepiridasulfonilureiaGrave

    • Sulfonamide derivatives: Patients who have developed an allergic reaction to sulfonamide derivatives may develop an allergic reaction to glimepiride tablets.Do not use glimepiride tablets in patients who have a history of an allergic reaction to sulfonamide derivatives. (bula de Glimepirida, Contraindicações)

  • GlipizidasulfonilureiaGrave

    • Hypersensitivity to sulfonamide derivatives. ▪ Known hypersensitivity to glipizide or any of the product's ingredients ( 4 ). ▪ Hypersensitivity to sulfonamide derivatives ( 4 ). (bula de Glipizida, Contraindicações)

  • Hidroclorotiazidadiurético tiazídicoGrave

    In patients with hypersensitivity to sulfonamide-derived drugs. (bula de Hidroclorotiazida, Contraindicações)

  • Indapamidadiurético tiazídicoGrave

    Known hypersensitivity to indapamide or to other sulfonamide-derived drugs. (bula de Indapamida, Contraindicações)

  • Irbesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Grave

    Because of the hydrochlorothiazide component, this product is contraindicated in patients with anuria or hypersensitivity to other sulfonamide-derived drugs. (bula de Irbesartana + hidroclorotiazida, Contraindicações)

  • Avoid diuretics or laxatives in patients with diarrhea. (bula de Irinotecano, Advertências e precauções)

  • Itraconazolantifúngico azólicoGrave

    Diuretics Eplerenone Contraindicated during and 2 weeks after TOLSURA treatment. (bula de Itraconazol, Interações medicamentosas)

  • Linagliptina + metforminainibidor da DPP-4Grave

    Risk factors for metformin-associated lactic acidosis include renal impairment, concomitant use of certain drugs (e.g., carbonic anhydrase inhibitors such as topiramate), age 65 years old or greater, having a radiological study with contrast, surgery and other procedures, hypoxic states (e.g., acute congestive heart failure), excessive alcohol intake, hepatic… (bula de Linagliptina + metformina, Advertência em caixa preta)

  • Lisinopril + hidroclorotiazidainibidor da ECAGrave

    Because of the hydrochlorothiazide component, this product is contraindicated in patients with anuria or hypersensitivity to other sulfonamide-derived drugs. (bula de Lisinopril + hidroclorotiazida, Contraindicações)

  • Mecamilaminaanti-hipertensivoGrave

    Patients receiving antibiotics and sulfonamides should generally not be treated with ganglion blockers. (bula de Mecamilamina, Contraindicações)

  • MetforminabiguanidaGrave

    Risk factors for metformin-associated lactic acidosis include renal impairment, concomitant use of certain drugs (e.g., carbonic anhydrase inhibitors such as topiramate), age 65 years old or greater, having a radiological study with contrast, surgery and other procedures, hypoxic states (e.g., acute congestive heart failure), excessive alcohol intake, and hepatic… (bula de Metformina, Advertência em caixa preta)

  • Anuria Hypersensitivity to metoprolol tartrate or hydrochlorothiazide or to other sulfonamide- derived drugs. (bula de Metoprolol + hidroclorotiazida, Contraindicações)

  • MinoxidilvasodilatadorGrave

    Minoxidil should be reserved for hypertensive patients who do not respond adequately to maximum therapeutic doses of a diuretic and two other antihypertensive agents. (bula de Minoxidil, Advertência em caixa preta)

  • NeomicinaaminoglicosídeoGrave

    The concurrent use of neomycin with potent diuretics such as ethacrynic acid or furosemide should be avoided, since certain diuretics by themselves may cause ototoxicity. (bula de Neomicina, Advertência em caixa preta)

  • Olmesartana + anlodipino + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Grave

    Because of the hydrochlorothiazide component, olmesartan medoxomil, amlodipine and hydrochlorothiazide tablet is contraindicated in patients with anuria, hypersensitivity to any component, or hypersensitivity to other sulfonamide-derived drugs. (bula de Olmesartana + anlodipino + hidroclorotiazida, Contraindicações)

  • Caution is advised for patients receiving concomitant high-dose aspirin and acetazolamide, as anorexia, tachypnea, lethargy, metabolic acidosis, coma, and death have been reported. (bula de Acetazolamida, Advertências)

  • Pioglitazona + glimepiridatiazolidinedionaGrave

    Use in patients with known history of an allergic reaction to sulfonamide derivatives. (bula de Pioglitazona + glimepirida, Contraindicações)

  • Pioglitazona + metforminatiazolidinedionaGrave

    Risk factors for metformin-associated lactic acidosis include renal impairment, concomitant use of certain drugs (e.g., carbonic anhydrase inhibitors such as topiramate), age 65 years old or greater, having a radiological study with contrast, surgery and other procedures, hypoxic states (e.g., acute congestive heart failure), excessive alcohol intake, hepatic… (bula de Pioglitazona + metformina, Advertência em caixa preta)

  • Quinaprilinibidor da ECAGrave

    …sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include patients with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (bula de Quinapril, Advertências)

  • Quinapril + hidroclorotiazidainibidor da ECAGrave

    Because of the hydrochlorothiazide components, this product is contraindicated in patients with anuria or hypersensitivity to other sulfonamide-derived drugs. (bula de Quinapril + hidroclorotiazida, Contraindicações)

  • Saxagliptina + metforminainibidor da DPP-4Grave

    • Risk factors for metformin-associated lactic acidosis include renal impairment, concomitant use of certain drugs (e.g., carbonic anhydrase inhibitors such as topiramate), age 65 years old or greater, having a radiological study with contrast, surgery and other procedures, hypoxic states (e.g., acute congestive heart failure ), excessive alcohol intake, hepatic… (bula de Saxagliptina + metformina, Advertência em caixa preta)

  • Sitagliptina + metforminainibidor da DPP-4Grave

    Risk factors for metformin-associated lactic acidosis include renal impairment, concomitant use of certain drugs (e.g., carbonic anhydrase inhibitors such as topiramate), age 65 years old or greater, having a radiological study with contrast, surgery and other procedures, hypoxic states (e.g., acute congestive heart failure), excessive alcohol intake, hepatic… (bula de Sitagliptina + metformina, Advertência em caixa preta)

  • TansulosinaalfabloqueadorGrave

    If a patient reports a serious or life-threatening sulfa allergy, caution is warranted when administering tamsulosin hydrochloride capsules. (bula de Tansulosina, Advertências e precauções)

  • TopiramatoanticonvulsivanteGrave

    Kidney stones: avoid use with other carbonic anhydrase inhibitors, drugs causing metabolic acidosis, or in patients on a ketogenic diet ( 5.13 ) (bula de Topiramato, Advertências e precauções)

  • Triantereno + hidroclorotiazidadiurético poupador de potássioGrave

    Hypersensitivity Hypersensitivity to either drug in the preparation or to other sulfonamide-derived drugs is a contraindication. (bula de Triantereno + hidroclorotiazida, Contraindicações)

  • Trióxido de arsêniomedicamento que prolonga o intervalo QTGrave

    The risk of torsade de pointes is related to the extent of QTc prolongation, concomitant administration of QTc prolonging drugs, a history of torsade de pointes, pre-existing QTc interval prolongation, congestive heart failure, administration of potassium-wasting diuretics, or other conditions that result in hypokalemia or hypomagnesemia. (bula de Trióxido de arsênio, Advertências e precauções)

  • Valsartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Grave

    Because of the hydrochlorothiazide component, this product is contraindicated in patients with anuria or hypersensitivity to other sulfonamide-derived drugs. (bula de Valsartana + hidroclorotiazida, Contraindicações)

Interações moderadas (255)

  • AcarboseantidiabéticoModerada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • AcebutololbetabloqueadorModerada

    Although β-blockers should be avoided in overt cardiac failure, acebutolol can be used with caution in patients with a history of heart failure who are controlled with digitalis and/or diuretics. (bula de Acebutolol, Advertências)

  • Ácido fólico (folato)Vitaminas e mineraisModerada

    Acetazolamide may increase the effects of other folic acid antagonists. (bula de Acetazolamida, Interações medicamentosas)

  • Ácido mefenâmicoAINEModerada

    Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors or ARBs, and the elderly. (bula de Ácido mefenâmico, Advertências e precauções)

  • Ácido valproicoanticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • Ácido zoledrônicobisfosfonatoModerada

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (bula de Ácido zoledrônico, Advertências e precauções)

  • Alisquirenoanti-hipertensivoModerada

    Risk factors for the development of hyperkalemia include renal insufficiency, diabetes, combination use with ARBs or ACEIs [see Contraindications ( 4 ), Warnings and Precautions ( 5.2 ), and Clinical Studies ( 14.3 )] , NSAIDs, or potassium supplements or potassium sparing diuretics. (bula de Alisquireno, Advertências e precauções)

  • AlmotriptanatriptanoModerada

    Use with caution in patients with a known hypersensitivity to sulfonamides ( 5.8 ) (bula de Almotriptana, Advertências e precauções)

  • Alogliptinainibidor da DPP-4Moderada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • Alopurinolinibidor da xantina oxidaseModerada

    Hypersensitivity reactions to allopurinol tablets may be increased in patients with decreased kidney function receiving thiazide diuretics and allopurinol tablets concurrently. (bula de Alopurinol, Advertências e precauções)

  • AmicacinaaminoglicosídeoModerada

    Ethacrynic Acid, Furosemide, Urea, or Mannitol Some diuretics can enhance aminoglycoside toxicity by altering aminoglycoside concentrations in serum and tissue. (bula de Amicacina, Interações medicamentosas)

  • AmiodaronaantiarrítmicoModerada

    Give special attention to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or in patients receiving concomitant diuretics and laxatives. (bula de Amiodarona, Advertências e precauções)

  • Anfepramona (dietilpropiona)estimulante do SNCModerada

    Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect. (bula de Acetazolamida, Interações medicamentosas)

  • Anfetaminaestimulante do SNCModerada

    Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect. (bula de Acetazolamida, Interações medicamentosas)

  • Anfetamina + dextroanfetaminaestimulante do SNCModerada

    Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect. (bula de Acetazolamida, Interações medicamentosas)

  • Anlodipino + benazeprilbloqueador dos canais de cálcio di-hidropiridínicoModerada

    Symptomatic hypotension is most likely to occur in patients who have heart failure, severe aortic or mitral stenosis, obstructive hypertrophic cardiomyopathy or have been volume or salt depleted as a result of diuretic therapy, dietary salt restriction, dialysis, diarrhea, or vomiting. (bula de Anlodipino + benazepril, Advertências e precauções)

  • Anlodipino + olmesartanabloqueador dos canais de cálcio di-hidropiridínicoModerada

    In patients with an activated renin-angiotensin system, such as volume and/or salt-depleted patients (e.g., those being treated with high doses of diuretics) symptomatic hypotension may be anticipated after initiation of treatment with olmesartan medoxomil . (bula de Anlodipino + olmesartana, Advertências e precauções)

  • Anlodipino + valsartanabloqueador dos canais de cálcio di-hidropiridínicoModerada

    In patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients receiving high doses of diuretics, symptomatic hypotension may occur in patients receiving angiotensin receptor blockers. (bula de Anlodipino + valsartana, Advertências e precauções)

  • Arformoterolagonista beta-adrenérgicoModerada

    Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (bula de Arformoterol, Interações medicamentosas)

  • Armodafinilaestimulante do SNCModerada

    Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect. (bula de Acetazolamida, Interações medicamentosas)

  • Articaína + epinefrinaanestésico localModerada

    …procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine Monoamine… (bula de Articaína + epinefrina, Interações medicamentosas)

  • Azilsartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Hypotension in Volume- or Salt-Depleted Patients In patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment with azilsartan medoxomil. (bula de Azilsartana, Advertências e precauções)

  • Beladona + ópioopioideModerada

    Diuretics Clinical Impact : Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Beladona + ópio, Interações medicamentosas)

  • Benazeprilinibidor da ECAModerada

    Patients at risk of excessive hypotension include those with the following conditions or characteristics: heart failure with systolic blood pressure below 100 mm Hg, ischemic heart disease, cerebrovascular disease, hyponatremia, high dose diuretic therapy, renal dialysis, or severe volume and/or salt depletion of any etiology. (bula de Benazepril, Advertências e precauções)

  • Benzfetaminaestimulante do SNCModerada

    Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect. (bula de Acetazolamida, Interações medicamentosas)

  • Bexagliflozinainibidor do SGLT2Moderada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • Brinzolamidainibidor da anidrase carbônicaModerada

    Because of possible additive effects with other carbonic anhydrase inhibitors, concomitant use is not advisable. (bula de Acetazolamida, Interações medicamentosas)

  • BrivaracetamanticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • Bromocriptinaagonista da dopaminaModerada

    Therefore, CYCLOSET may increase the unbound fraction of other concomitantly used highly protein-bound therapies (e.g., salicylates, sulfonamides, chloramphenicol and probenecid), which may alter their effectiveness and risk for side effects. (bula de Bromocriptina, Interações medicamentosas)

  • Budesonida + formoterolcorticosteroideModerada

    Diuretics: Use with caution. (bula de Budesonida + formoterol, Interações medicamentosas)

  • Bumetanidadiurético de alçaModerada

    Like other members of this class of diuretics, bumetanide probably shares this risk. (bula de Bumetanida, Advertências)

  • Bupivacaína + epinefrinaanestésico localModerada

    …procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine 7.6 Potent… (bula de Bupivacaína + epinefrina, Interações medicamentosas)

  • BuprenorfinaopioideModerada

    Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Buprenorfina, Interações medicamentosas)

  • Examples: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Buprenorfina + naloxona, Interações medicamentosas)

  • Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect. (bula de Acetazolamida, Interações medicamentosas)

  • Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect. (bula de Acetazolamida, Interações medicamentosas)

  • By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • Canagliflozinainibidor do SGLT2Moderada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • Candesartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Symptomatic hypotension is most likely to occur in patients who have been volume and/or salt depleted as a result of prolonged diuretic therapy, dietary salt restriction, dialysis, diarrhea, or vomiting. (bula de Candesartana, Advertências e precauções)

  • Captoprilinibidor da ECAModerada

    Hypotension Excessive hypotension was rarely seen in hypertensive patients but is a possible consequence of captopril use in salt/volume depleted persons (such as those treated vigorously with diuretics), patients with heart failure or those patients undergoing renal dialysis (see PRECAUTIONS : Drug Interactions ). (bula de Captopril, Advertências)

  • CarbamazepinaanticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • CarvedilolbetabloqueadorModerada

    If such symptoms occur, diuretics should be increased and the carvedilol dose should not be advanced until clinical stability resumes [see Dosage and Administration (2) ] . (bula de Carvedilol, Advertências e precauções)

  • CefepimacefalosporinaModerada

    Diuretics: Nephrotoxicity has been reported with concomitant administration of cephalosporins with potent diuretics such as furosemide. (bula de Cefepima, Interações medicamentosas)

  • CeftazidimacefalosporinaModerada

    Drug Interactions Nephrotoxicity has been reported following concomitant administration of cephalosporins with aminoglycoside antibacterial drugs or potent diuretics such as furosemide. (bula de Ceftazidima, Interações medicamentosas)

  • CenobamatoanticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • Cetoconazolantifúngico azólicoModerada

    Diuretics eplerenone The potential increase in plasma concentrations of eplerenone when coadministered with ketoconazole tablets may increase the risk of hyperkalemia and hypotension. (bula de Cetoconazol, Interações medicamentosas)

  • CetoprofenoAINEModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics, and the elderly. (bula de Cetoprofeno, Advertências e precauções)

  • CetorolacoAINEModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • CiclofosfamidaimunossupressorModerada

    …inhibitors can cause leukopenia. ● Natalizumab ● Paclitaxel: Increased hematotoxicity has been reported when cyclophosphamide was administered after paclitaxel infusion. ● Thiazide diuretics ● Zidovudine Increased cardiotoxicity ● Anthracyclines ● Cytarabine ● Pentostatin ● Radiation therapy of the cardiac region ● Trastuzumab Increased pulmonary toxicity ● Amiodarone… (bula de Ciclofosfamida, Interações medicamentosas)

  • Increase the dose of diuretics as needed [see Adverse Reactions (6) ] . (bula de Ciclossilicato de zircônio sódico, Advertências e precauções)

  • CitalopramISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume depleted may be at greater risk for developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (bula de Citalopram, Advertências e precauções)

  • ClobazambenzodiazepínicoModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • ClofarabinaantimetabólitoModerada

    Consider use of diuretics and/or albumin. (bula de Clofarabina, Advertências e precauções)

  • ClonazepambenzodiazepínicoModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • Drugs That Increase the Risk of Hypercalcemia Increase frequency of monitoring of calcium concentrations in patients taking concomitant Calcium Chloride Injection and other drugs that increase the risk of hypercalcemia (e.g., calcipotriene, estrogen, lithium, parathyroid hormone, teriparatide, thiazide diuretics, Vitamin A, and Vitamin D). (bula de Cloreto de cálcio, Interações medicamentosas)

  • ClorpromazinaantipsicóticoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (bula de Clorpromazina, Precauções)

  • ClozapinaantipsicóticoModerada

    Hypokalemia can result from diuretic therapy, diarrhea, and other causes. (bula de Clozapina, Advertências e precauções)

  • CodeínaopioideModerada

    Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Codeína, Interações medicamentosas)

  • Colestiraminasequestrante de ácidos biliaresModerada

    Drug Interactions Cholestyramine for Oral Suspension USP may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics (acidic), or propranolol (basic), as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins, and digitalis. (bula de Colestiramina, Interações medicamentosas)

  • Dapagliflozinainibidor do SGLT2Moderada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • DarunavirantirretroviralModerada

    Use with caution in patients with a known sulfonamide allergy. (bula de Darunavir, Advertências e precauções)

  • Darunavir + cobicistateantirretroviralModerada

    Monitor in patients with a known sulfonamide allergy. (bula de Darunavir + cobicistate, Advertências e precauções)

  • Desipraminaantidepressivo tricíclicoModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with NORPRAMIN. (bula de Desipramina, Advertências)

  • …Hyponatremia Concomitant administration of DESMODA with other drugs that may increase the risk of water intoxication with hyponatremia, (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, thiazide diuretics, NSAIDs, lamotrigine, sulfonylureas, particularly chlorpropamide, oxybutynin and carbamazepine). (bula de Desmopressina, Interações medicamentosas)

  • DesvenlafaxinaIRSNModerada

    Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk [see Use in Specific Populations (8.5) and Clinical Pharmacology (12.3) ] . (bula de Desvenlafaxina, Advertências e precauções)

  • Dexlansoprazolinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (bula de Dexlansoprazol, Advertências e precauções)

  • Dexmetilfenidatoestimulante do SNCModerada

    Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect. (bula de Acetazolamida, Interações medicamentosas)

  • Dextroanfetaminaestimulante do SNCModerada

    Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect. (bula de Acetazolamida, Interações medicamentosas)

  • Dextrometorfano + quinidinamedicamento serotoninérgicoModerada

    Acetazolamide reduces urinary excretion of quinidine and may enhance its effect. (bula de Acetazolamida, Interações medicamentosas)

  • DiazóxidoModerada

    The concomitant administration of thiazides or other diuretics may potentiate the hyperglycemic and hyperuricemic effects of PROGLYCEM. (bula de Diazóxido, Interações medicamentosas)

  • DiclofenacoAINEModerada

    Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors or ARBs, and the elderly. (bula de Diclofenaco, Advertências e precauções)

  • Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors or ARBs, and the elderly. (bula de Diclofenaco + misoprostol, Advertências e precauções)

  • DiflunisalAINEModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, patients who are volume depleted, and the elderly. (bula de Diflunisal, Advertências)

  • Digoxinaglicosídeo digitálicoModerada

    Serum potassium levels should be carefully monitored when digoxin is given to patients at high risk of hypokalemia ( e.g. , those receiving diuretics, corticosteroids, or other drugs that commonly lead to potassium loss; those with gastrointestinal losses through diarrhea, vomiting, or nasogastric suction; or those with potassium-losing endocrinopathies or nephropathies). (bula de Digoxina, Advertências e precauções)

  • Divalproato de sódio (valproato)anticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • Dorzolamidainibidor da anidrase carbônicaModerada

    Because of possible additive effects with other carbonic anhydrase inhibitors, concomitant use is not advisable. (bula de Acetazolamida, Interações medicamentosas)

  • Dorzolamida + timololinibidor da anidrase carbônicaModerada

    Because of possible additive effects with other carbonic anhydrase inhibitors, concomitant use is not advisable. (bula de Acetazolamida, Interações medicamentosas)

  • Doxercalciferolanálogo da vitamina DModerada

    Risk may be increased when used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (bula de Doxercalciferol, Advertências e precauções)

  • Drospirenona + etinilestradiolanticoncepcional oralModerada

    Medications that may increase serum potassium concentration include ACE inhibitors, angiotensin-II receptor antagonists, potassium-sparing diuretics, potassium supplementation, heparin, aldosterone antagonists, and NSAIDS. (bula de Drospirenona + etinilestradiol, Advertências e precauções)

  • Dulaglutidaagonista do receptor de GLP-1Moderada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • DuloxetinaIRSNModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (bula de Duloxetina, Advertências e precauções)

  • Empagliflozinainibidor do SGLT2Moderada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • Enalaprilinibidor da ECAModerada

    Patients at risk of excessive hypotension include those with the following conditions or characteristics: heart failure with systolic blood pressure below 100 mmHg, ischemic heart disease, cerebrovascular disease, hyponatremia, high dose diuretic therapy, renal dialysis, or severe volume and/or salt depletion of any etiology. (bula de Enalapril, Advertências e precauções)

  • Epinefrina (adrenalina)simpaticomiméticoModerada

    …Precautions (5.6) and Adverse Reactions (6) ]. β-blockers, such as propranolol Cyclopropane or halogenated hydrocarbon anesthetics, such as halothane Antihistamines Thyroid hormones Diuretics Cardiac glycosides, such as digitalis glycosides Quinidine Drugs potentiating hypokalemic effects of epinephrine • Potassium depleting diuretics • Corticosteroids • Theophylline… (bula de Epinefrina (adrenalina), Interações medicamentosas)

  • Epoprostenolanálogo de prostaglandinaModerada

    Additional reductions in blood pressure may occur when VELETRI is administered with diuretics, antihypertensive agents, or other vasodilators. (bula de Epoprostenol, Interações medicamentosas)

  • Ergotamina + cafeínaalcaloide do ergotModerada

    Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect. (bula de Acetazolamida, Interações medicamentosas)

  • EscitalopramISRSModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • EslicarbazepinaanticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • Esomeprazolinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (bula de Esomeprazol, Advertências e precauções)

  • Espironolactonaantagonista da aldosteronaModerada

    …drugs that can increase potassium include: ACE inhibitors angiotensin receptor blockers aldosterone blockers non-steroidal anti-inflammatory drugs (NSAIDs) heparin and low molecular weight heparin trimethoprim 7.2 Lithium Like other diuretics, spironolactone oral suspension reduces the renal clearance of lithium, thus increasing the risk of lithium toxicity. (bula de Espironolactona, Interações medicamentosas)

  • EtodolacoAINEModerada

    Patients at greater risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Etodolaco, Advertências)

  • EtossuximidaanticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • Exenatidaagonista do receptor de GLP-1Moderada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • FelbamatoanticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • Fendimetrazinaestimulante do SNCModerada

    Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect. (bula de Acetazolamida, Interações medicamentosas)

  • Fenelzinainibidor da MAOModerada

    …hydrochloride desipramine hydrochloride imipramine hydrochloride doxepin carbamazepine cyclobenzaprine HCl amoxapine maprotiline HCl trimipramine maleate protriptyline HCl mirtazapine Phenelzine sulfate should be used with caution in combination with antihypertensive drugs, including thiazide diuretics and β-blockers, since exaggerated hypotensive effects may result. (bula de Fenelzina, Advertências)

  • FenitoínaanticonvulsivanteModerada

    Acetazolamide modifies phenytoin metabolism with increased serum levels of phenytoin. (bula de Acetazolamida, Interações medicamentosas)

  • FenobarbitalbarbitúricoModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • FenoprofenoAINEModerada

    Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors or ARBs, and the elderly. (bula de Fenoprofeno, Advertências e precauções)

  • FentanilaopioideModerada

    …treatment with Class 1 and Class III antiarrhythmics, 4) treatment with monoamine oxidase inhibitors (MAOI's), 5) concomitant treatment with other drug products known to prolong the QT interval and 6) electrolyte imbalance, in particular hypokalemia and hypomagnesemia, or concomitant treatment with drugs (e.g., diuretics) that may cause electrolyte imbalance. (bula de Fentanila, Advertências e precauções)

  • Fenterminaestimulante do SNCModerada

    Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect. (bula de Acetazolamida, Interações medicamentosas)

  • Fluconazolantifúngico azólicoModerada

    An effect of this magnitude should not necessitate a change in the fluconazole dose regimen in subjects receiving concomitant diuretics. (bula de Fluconazol, Interações medicamentosas)

  • FludrocortisonacorticosteroideModerada

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (bula de Fludrocortisona, Interações medicamentosas)

  • FluoxetinaISRSModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (bula de Fluoxetina, Advertências e precauções)

  • FlurbiprofenoAINEModerada

    Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors or ARBs, and the elderly. (bula de Flurbiprofeno, Advertências e precauções)

  • Fluticasona + salmeterolcorticosteroideModerada

    Diuretics: Use with caution. (bula de Fluticasona + salmeterol, Interações medicamentosas)

  • FluvoxaminaISRSModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Fluvoxamina, Advertências e precauções)

  • Formoterolagonista beta-adrenérgicoModerada

    • Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (bula de Formoterol, Interações medicamentosas)

  • FosamprenavirantirretroviralModerada

    Fosamprenavir calcium should be used with caution in patients with a known sulfonamide allergy. (bula de Fosamprenavir, Advertências e precauções)

  • FoscarneteantiviralModerada

    When diuretics are indicated, thiazides are recommended over loop diuretics because the latter inhibit renal tubular secretion, and may impair elimination of FOSCAVIR, potentially leading to toxicity. (bula de Foscarnete, Interações medicamentosas)

  • FosfenitoínaanticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • Fosinoprilinibidor da ECAModerada

    Symptomatic hypotension is most likely to occur in patients who have been volume- and/or salt-depleted as a result of prolonged diuretic therapy, dietary salt restriction, dialysis, diarrhea, or vomiting. (bula de Fosinopril, Advertências)

  • GabapentinaanticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • GlibenclamidasulfonilureiaModerada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • Glipizida + metforminasulfonilureiaModerada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • HaloperidolantipsicóticoModerada

    Caution is advised when haloperidol decanoate is used in combination with drugs known to cause electrolyte imbalance (e.g., diuretics or corticosteroids) because hypokalemia, hypomagnesemia, and hypocalcemia are risk factors for QT prolongation. (bula de Haloperidol, Interações medicamentosas)

  • HidrocodonaopioideModerada

    Example: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Hidrocodona, Interações medicamentosas)

  • Diuretics : Hydrocodone may reduce the efficacy of diuretics. (bula de Hidrocodona + clorfeniramina, Interações medicamentosas)

  • Diuretics : Hydrocodone may reduce the efficacy of diuretics. (bula de Hidrocodona + homatropina, Interações medicamentosas)

  • Patients taking angiotensin converting enzyme (ACE) inhibitors, thiazide diuretics, or loop diuretics may have impaired response to these therapies when taking NSAIDs (see PRECAUTIONS: Drug Interactions). (bula de Hidrocodona + ibuprofeno, Advertências)

  • Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Hidrocodona + paracetamol, Interações medicamentosas)

  • HidromorfonaopioideModerada

    Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Hidromorfona, Interações medicamentosas)

  • IbuprofenoAINEModerada

    Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors or ARBs, and the elderly. (bula de Ibuprofeno, Advertências e precauções)

  • Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE-inhibitors or ARBs, and the elderly. (bula de Ibuprofeno + famotidina, Advertências e precauções)

  • Imipraminaantidepressivo tricíclicoModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with imipramine hydrochloride tablets. (bula de Imipramina, Advertências)

  • IndometacinaAINEModerada

    Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors or ARBs, and the elderly. (bula de Indometacina, Advertências e precauções)

  • Insulina asparteinsulinaModerada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • Insulina degludecainsulinaModerada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • Insulina detemirinsulinaModerada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • Insulina glarginainsulinaModerada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • Insulina lisproinsulinaModerada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • Concurrent use with potassium-containing medications, potassium-sparing diuretics and angiotensin-converting enzyme inhibitors (ACE inhibitors) may result in hyperkalemia and cardiac arrhythmias or cardiac arrest. (bula de Iodeto de potássio, Interações medicamentosas)

  • Ipratrópio + salbutamolanticolinérgicoModerada

    Diuretics The electrocardiogram (ECG) changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by β-agonists, especially when the recommended dose of the β-agonist is exceeded. (bula de Ipratrópio + salbutamol, Interações medicamentosas)

  • Irbesartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Hypotension in Volume or Salt-Depleted Patients In patients with an activated renin-angiotensin system, such as volume or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initialization of treatment with AVAPRO. (bula de Irbesartana, Advertências e precauções)

  • LacosamidaanticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • LamotriginaanticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • Lansoprazolinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (bula de Lansoprazol, Advertências e precauções)

  • LevetiracetamanticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • LevomilnacipranaIRSNModerada

    Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk. (bula de Levomilnaciprana, Advertências e precauções)

  • LevorfanolopioideModerada

    Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Levorfanol, Interações medicamentosas)

  • Levossalbutamolagonista beta-adrenérgicoModerada

    Diuretics The ECG changes or hypokalemia that may result from the administration of non-potassium-sparing diuretics (such as loop and thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. (bula de Levossalbutamol, Interações medicamentosas)

  • Lidocaína + epinefrinaanestésico localModerada

    …procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea, isofamide, rasburicase Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine 7.6 Potent… (bula de Lidocaína + epinefrina, Interações medicamentosas)

  • Linagliptinainibidor da DPP-4Moderada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • LinezolidaantibióticoModerada

    Monitor serum sodium levels regularly in the elderly, in patients taking diuretics, and in other patients at risk of hyponatremia and/or SIADH while taking Linezolid injection. (bula de Linezolida, Advertências e precauções)

  • Liraglutidaagonista do receptor de GLP-1Moderada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • Lisdexanfetaminaestimulante do SNCModerada

    Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect. (bula de Acetazolamida, Interações medicamentosas)

  • Lisinoprilinibidor da ECAModerada

    Patients at risk of excessive hypotension include those with the following conditions or characteristics: heart failure with systolic blood pressure below 100 mmHg, ischemic heart disease, cerebrovascular disease, hyponatremia, high dose diuretic therapy, renal dialysis, or severe volume and/or salt depletion of any etiology. (bula de Lisinopril, Advertências e precauções)

  • Lítiomedicamento serotoninérgicoModerada

    Acetazolamide increases lithium excretion and the lithium may be decreased. (bula de Acetazolamida, Interações medicamentosas)

  • Losartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Hypotension in Volume- or Salt-Depleted Patients In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment with COZAAR. (bula de Losartana, Advertências e precauções)

  • Losartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Losartana + hidroclorotiazida, Advertências e precauções)

  • MeloxicamAINEModerada

    Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors or ARBs, and the elderly. (bula de Meloxicam, Advertências e precauções)

  • Mepivacaínaanestésico localModerada

    …procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine (bula de Mepivacaína, Interações medicamentosas)

  • Mesuximida (metossuximida)anticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • MetadonaopioideModerada

    Closely monitor patients with risk factors for development of prolonged QT interval (e.g., cardiac hypertrophy, concomitant diuretic use, hypokalemia, hypomagnesemia), a history of cardiac conduction abnormalities, and those taking medications affecting cardiac conduction. (bula de Metadona, Advertências e precauções)

  • Metanfetaminaestimulante do SNCModerada

    Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect. (bula de Acetazolamida, Interações medicamentosas)

  • Metazolamidainibidor da anidrase carbônicaModerada

    Because of possible additive effects with other carbonic anhydrase inhibitors, concomitant use is not advisable. (bula de Acetazolamida, Interações medicamentosas)

  • Metilfenidatoestimulante do SNCModerada

    Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect. (bula de Acetazolamida, Interações medicamentosas)

  • Metolazonadiurético tiazídicoModerada

    Anticoagulants Metolazone, as well as other thiazide-like diuretics, may affect the hypoprothrombinemic response to anticoagulants; dosage adjustments may be necessary. (bula de Metolazona, Interações medicamentosas)

  • MetoprololbetabloqueadorModerada

    If such symptoms occur, increase diuretics and restore clinical stability before advancing the dose of Metoprolol Tartrate Tablets [see Dosage and Administration (2) ]. (bula de Metoprolol, Advertências e precauções)

  • MiglitolantidiabéticoModerada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • MilnacipranaIRSNModerada

    Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Geriatric Use ( 8.5 )] . (bula de Milnaciprana, Advertências e precauções)

  • MirtazapinaantidepressivoModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia [see Use in Specific Populations (8.5) ] . (bula de Mirtazapina, Advertências e precauções)

  • Modafinilaestimulante do SNCModerada

    Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect. (bula de Acetazolamida, Interações medicamentosas)

  • Moexiprilinibidor da ECAModerada

    Symptomatic hypotension is most likely to occur in patients who have been salt- and volume- depleted as a result of prolonged diuretic therapy, dietary salt restriction, dialysis, diarrhea, or vomiting. (bula de Moexipril, Advertências)

  • MorfinaopioideModerada

    Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Morfina, Interações medicamentosas)

  • NabumetonaAINEModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics, and the elderly. (bula de Nabumetona, Advertências)

  • NadololbetabloqueadorModerada

    Although beta-blockers should be avoided in overt congestive heart failure, if necessary, they can be used with caution in patients with a history of failure who are well-compensated, usually with digitalis and diuretics. (bula de Nadolol, Advertências)

  • NalbufinaopioideModerada

    Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Nalbufina, Interações medicamentosas)

  • NaproxenoAINEModerada

    Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors or ARBs, and the elderly. (bula de Naproxeno, Advertências e precauções)

  • Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE-inhibitors or ARBs, and the elderly. (bula de Naproxeno + esomeprazol, Advertências e precauções)

  • NateglinidameglitinidaModerada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • Nifedipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Other Diuretics, PDE5 inhibitors, alpha-methyldopa: Nifedipine may increase the blood pressure lowering effect of these concomitantly administered agents. (bula de Nifedipino, Interações medicamentosas)

  • Nimodipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Blood Pressure Lowering Drugs Nimodipine may increase the blood pressure lowering effect of concomitantly administered anti-hypertensives such as diuretics, beta-blockers, ACE inhibitors, angiotensin receptor blockers, other calcium channel blockers, α-adrenergic blockers, PDE5 inhibitors, and α-methyldopa. (bula de Nimodipino, Interações medicamentosas)

  • Olanzapina + fluoxetinaantipsicóticoModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Olanzapina + fluoxetina, Advertências e precauções)

  • OliceridinaopioideModerada

    Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Oliceridina, Interações medicamentosas)

  • Olmesartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Hypotension in Volume- or Salt-Depleted Patients In patients with an activated renin-angiotensin-aldosterone system, such as volume- and/or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may be anticipated after initiation of treatment with Benicar. (bula de Olmesartana, Advertências e precauções)

  • Olmesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Olmesartana + hidroclorotiazida, Advertências e precauções)

  • Omeprazolinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (bula de Omeprazol, Advertências e precauções)

  • Omeprazol + bicarbonato de sódioinibidor da bomba de prótonsModerada

    Acetazolamide and sodium bicarbonate used concurrently increases the risk of renal calculus formation. (bula de Acetazolamida, Interações medicamentosas)

  • OxaprozinaAINEModerada

    Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors or ARBs, and the elderly. (bula de Oxaprozina, Advertências e precauções)

  • OxcarbazepinaanticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • OxicodonaopioideModerada

    Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Oxicodona, Interações medicamentosas)

  • Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Oxicodona + paracetamol, Interações medicamentosas)

  • OximorfonaopioideModerada

    Examples: butorphanol, nalbuphine, pentazocine, buprenorphine Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Oximorfona, Interações medicamentosas)

  • Pantoprazolinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (bula de Pantoprazol, Advertências e precauções)

  • Paracetamol + codeínaopioideModerada

    Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Paracetamol + codeína, Interações medicamentosas)

  • Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors or ARBs, and the elderly. (bula de Paracetamol + ibuprofeno, Advertências e precauções)

  • Paricalcitolanálogo da vitamina DModerada

    The risk may be increased when Paricalcitol Injection is used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (bula de Paricalcitol, Advertências e precauções)

  • ParoxetinaISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SNRIs and SSRIs. [see Use in Specific Populations ( 8.5 )]. (bula de Paroxetina, Advertências e precauções)

  • Pentazocina + naloxonaopioideModerada

    Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Pentazocina + naloxona, Interações medicamentosas)

  • PerampanelanticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • Perindoprilinibidor da ECAModerada

    Symptomatic hypotension is most likely to occur in patients who have been volume or salt-depleted as a result of prolonged diuretic therapy, dietary salt restriction, dialysis, diarrhea or vomiting [see Dosage and Administration (2.1) ] . (bula de Perindopril, Advertências e precauções)

  • Petidina (meperidina)opioideModerada

    Examples: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Petidina (meperidina), Interações medicamentosas)

  • PindololbetabloqueadorModerada

    Although beta-blockers should be avoided in overt congestive heart failure, if necessary, pindolol tablets can be used with caution in patients with a history of failure who are well-compensated, usually with digitalis and diuretics. (bula de Pindolol, Advertências)

  • PioglitazonatiazolidinedionaModerada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • PirimetaminaantimaláricoModerada

    However, the concomitant use of other antifolic drugs or agents associated with myelosuppression including sulfonamides or trimethoprim- sulfamethoxazole combinations, proguanil, zidovudine, or cytostatic agents (e.g., methotrexate), while the patient is receiving pyrimethamine, may increase the risk of bone marrow suppression. (bula de Pirimetamina, Interações medicamentosas)

  • PiroxicamAINEModerada

    Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors or ARBs, and the elderly. (bula de Piroxicam, Advertências e precauções)

  • PrazosinaalfabloqueadorModerada

    Addition of a diuretic or other antihypertensive agent to prazosin hydrochloride capsules has been shown to cause an additive hypotensive effect. (bula de Prazosina, Interações medicamentosas)

  • PregabalinaanticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • Prilocaína + epinefrinaanestésico localModerada

    …procaine, ropivacaine, tetracaine Antineoplastic Agents cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine The administration… (bula de Prilocaína + epinefrina, Interações medicamentosas)

  • PrimidonaanticonvulsivanteModerada

    Caution is advised when beginning, discontinuing, or changing the dose of acetazolamide in patients receiving primidone. (bula de Acetazolamida, Interações medicamentosas)

  • ProbenecidaModerada

    Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (bula de Probenecida, Interações medicamentosas)

  • Probenecid produces an insignificant increase in free sulfonamide plasma concentrations but a significant increase in total sulfonamide plasma levels. (bula de Probenecida + colchicina, Interações medicamentosas)

  • ProclorperazinaantipsicóticoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (bula de Proclorperazina, Precauções)

  • Prometazina + codeínaopioideModerada

    Diuretics : Codeine may reduce the efficacy of diuretics. (bula de Prometazina + codeína, Interações medicamentosas)

  • QuinidinaantiarrítmicoModerada

    Acetazolamide reduces urinary excretion of quinidine and may enhance its effect. (bula de Acetazolamida, Interações medicamentosas)

  • QuininaantimaláricoModerada

    Urinary Alkalizers (Acetazolamide, Sodium Bicarbonate) Urinary alkalinizing agents may increase plasma quinine concentrations. (bula de Quinina, Interações medicamentosas)

  • Rabeprazolinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (bula de Rabeprazol, Advertências e precauções)

  • Ramiprilinibidor da ECAModerada

    Experience with another ACE inhibitor suggests that these increases would be reversible upon discontinuation of ramipril and/or diuretic therapy. (bula de Ramipril, Advertências e precauções)

  • RepaglinidameglitinidaModerada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • Ropivacaínaanestésico localModerada

    …procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants Phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine NAROPIN… (bula de Ropivacaína, Interações medicamentosas)

  • RufinamidaanticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • Sacubitril + valsartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients (e.g., those being treated with high doses of diuretics), are at greater risk. (bula de Sacubitril + valsartana, Advertências e precauções)

  • Salbutamolagonista beta-adrenérgicoModerada

    Diuretics: Use with caution. (bula de Salbutamol, Interações medicamentosas)

  • Salmeterolagonista beta-adrenérgicoModerada

    • Diuretics: Use with caution. (bula de Salmeterol, Interações medicamentosas)

  • SalsalatoAINEModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Saxagliptinainibidor da DPP-4Moderada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • Semaglutidaagonista do receptor de GLP-1Moderada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • SertralinaISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (bula de Sertralina, Advertências e precauções)

  • Sitagliptinainibidor da DPP-4Moderada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • Solriamfetolestimulante do SNCModerada

    Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect. (bula de Acetazolamida, Interações medicamentosas)

  • SotalolbetabloqueadorModerada

    Special attention should be given to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or patients receiving concomitant diuretic drugs. (bula de Sotalol, Advertências e precauções)

  • Drug Interactions In elderly patients concurrently receiving certain diuretics, primarily thiazides, an increased incidence of thrombocytopenia with purpura has been reported. (bula de Sulfametoxazol + trimetoprima, Interações medicamentosas)

  • SulindacoAINEModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, patients who are volume-depleted, and the elderly. (bula de Sulindaco, Advertências)

  • Sumatriptana + naproxenotriptanoModerada

    Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, salt depletion, those taking diuretics and angiotensin-converting enzyme (ACE) inhibitors or ARBs, and the elderly. (bula de Sumatriptana + naproxeno, Advertências e precauções)

  • Suxametônio (succinilcolina)bloqueador neuromuscularModerada

    Prolonged Neuromuscular Block in Patients with Hypokalemia or Hypocalcemia Neuromuscular blockade may be prolonged in patients with hypokalemia (e.g., after severe vomiting, diarrhea, digitalisation and diuretic therapy) or hypocalcemia (e.g., after massive transfusions). (bula de Suxametônio (succinilcolina), Advertências e precauções)

  • TacrolimoimunossupressorModerada

    Concomitant use of agents associated with hyperkalemia (e.g., potassium-sparing diuretics, ACE inhibitors, angiotensin receptor blockers) may increase the risk for hyperkalemia [see Adverse Reactions ( 6.1 )] . (bula de Tacrolimo, Advertências e precauções)

  • TapentadolopioideModerada

    …use of skeletal muscle relaxants and opioids, consider prescribing naloxone for the emergency treatment of opioid overdose [see Dosage and Administration (2.2) , Warnings and Precautions (5.2 , 5.3) ] Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Tapentadol, Interações medicamentosas)

  • Telmisartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Hypotension In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of therapy with telmisartan tablets. (bula de Telmisartana, Advertências e precauções)

  • Telmisartana + anlodipinobloqueador do receptor da angiotensina II (BRA)Moderada

    Hypotension Telmisartan In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of therapy with telmisartan and amlodipine tablets. (bula de Telmisartana + anlodipino, Advertências e precauções)

  • Telmisartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Telmisartana + hidroclorotiazida, Advertências e precauções)

  • Terbutalinaagonista beta-adrenérgicoModerada

    Diuretics The ECG changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. (bula de Terbutalina, Precauções)

  • TiagabinaanticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • Tirzepatidaagonista do receptor de GLP-1Moderada

    Consideration should be taken in patients being treated with antidiabetic agents. (bula de Acetazolamida, Interações medicamentosas)

  • TobramicinaaminoglicosídeoModerada

    Some diuretics can enhance aminoglycoside toxicity by altering antibiotic concentrations in serum and tissue. (bula de Tobramicina, Interações medicamentosas)

  • TolmetinaAINEModerada

    Use of tolmetin may blunt the CV effects of several therapeutic agents used to treat these medical conditions [e.g., diuretics, ACE inhibitors, or angiotensin receptor blockers (ARBs)] (see PRECAUTIONS: Drug Interactions ). (bula de Tolmetina, Advertências)

  • TolvaptanaModerada

    Co-administration of diuretics also increases the risk of too rapid correction of serum sodium and such patients should undergo close monitoring of serum sodium. (bula de Tolvaptana, Advertências e precauções)

  • Torasemidadiurético de alçaModerada

    Lithium Like other diuretics, torsemide reduces the renal clearance of lithium, inducing a high risk of lithium toxicity. (bula de Torasemida, Interações medicamentosas)

  • Toremifenomodulador seletivo do receptor de estrogênioModerada

    Drugs that decrease renal calcium excretion, e.g., thiazide diuretics, may increase the risk of hypercalcemia in patients receiving FARESTON. (bula de Toremifeno, Interações medicamentosas)

  • TramadolopioideModerada

    Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Tramadol, Interações medicamentosas)

  • Tramadol + paracetamolopioideModerada

    Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Tramadol + paracetamol, Interações medicamentosas)

  • Trandolaprilinibidor da ECAModerada

    Symptomatic hypotension is most likely to occur in patients who have been salt- or volume-depleted as a result of prolonged treatment with diuretics, dietary salt restriction, dialysis, diarrhea, or vomiting. (bula de Trandolapril, Advertências)

  • TrazodonaantidepressivoModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs and SNRIs [see Use in Specific Populations (8.5) ] . (bula de Trazodona, Advertências e precauções)

  • Trianterenodiurético poupador de potássioModerada

    The effects of the following drugs may be potentiated when given together with triamterene: antihypertensive medication, other diuretics, preanesthetic and anesthetic agents, skeletal muscle relaxants (non-depolarizing). (bula de Triantereno, Interações medicamentosas)

  • TrifluoperazinaantipsicóticoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (bula de Trifluoperazina, Precauções)

  • Umeclidínio + vilanterolanticolinérgicoModerada

    • Diuretics: Use with caution. (bula de Umeclidínio + vilanterol, Interações medicamentosas)

  • Valsartanabloqueador do receptor da angiotensina II (BRA)Moderada

    In patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients receiving high doses of diuretics, symptomatic hypotension may occur. (bula de Valsartana, Advertências e precauções)

  • VenlafaxinaIRSNModerada

    Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (bula de Venlafaxina, Advertências e precauções)

  • Verapamilbloqueador dos canais de cálcioModerada

    Control patients with milder ventricular dysfunction, if possible, with optimum doses of digitalis and/or diuretics before verapamil treatment is started [see Drug Interactions ( 7.5 )] . (bula de Verapamil, Advertências e precauções)

  • VigabatrinaanticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

  • VilazodonaISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs and SNRIs [see Use in Specific Populations ( 8.5 )] . (bula de Vilazodona, Advertências e precauções)

  • VortioxetinaantidepressivoModerada

    Also, patients taking diuretics or who are otherwise volume-depleted can be at greater risk. (bula de Vortioxetina, Advertências e precauções)

  • ZiprasidonaantipsicóticoModerada

    Hypokalemia may result from diuretic therapy, diarrhea, and other causes. (bula de Ziprasidona, Advertências e precauções)

  • ZonisamidaanticonvulsivanteModerada

    By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. (bula de Acetazolamida, Interações medicamentosas)

Menções leves (30)

  • Patients required intervention with a diuretic, fluid management, or, in some cases, hospitalization for decompensating heart failure. (bula de Ambrisentana, Advertências e precauções)

  • Amoxicilinaantibiótico da classe das penicilinasLeve

    Other Antibacterials Chloramphenicol, macrolides, sulfonamides, and tetracyclines may interfere with the bactericidal effects of penicillin. (bula de Amoxicilina, Interações medicamentosas)

  • Ampicilinaantibiótico da classe das penicilinasLeve

    Bacteriostatic Antibiotics : Chloramphenicol, erythromycins, sulfonamides, or tetracyclines may interfere with the bactericidal effect of penicillins. (bula de Ampicilina, Interações medicamentosas)

  • Azul de metilenoinibidor da MAOLeve

    Lack of Effectiveness Methemoglobinemia may not resolve or may rebound after response to treatment with PROVAYBLUE in patients with methemoglobinemia due to aryl amines such as aniline or sulfa drugs such as dapsone. (bula de Azul de metileno, Advertências e precauções)

  • Benzilpenicilina (penicilina G)antibiótico da classe das penicilinasLeve

    Drug Interactions Bacteriostatic antibacterials ( i.e. , chloramphenicol, erythromycins, sulfonamides or tetracyclines) may antagonize the bactericidal effect of penicillin, and concurrent use of these drugs should be avoided. (bula de Benzilpenicilina (penicilina G), Interações medicamentosas)

  • BetaxololbetabloqueadorLeve

    In hypertensive patients who have congestive heart failure controlled by digitalis and diuretics, beta-blockers should be administered cautiously. (bula de Betaxolol, Advertências)

  • Bosentanaindutor da CYP3A4Leve

    Patients required intervention with a diuretic, fluid management, or hospitalization for decompensating heart failure. (bula de Bosentana, Advertências e precauções)

  • Acthar Gel may accentuate the electrolyte loss associated with diuretic therapy. (bula de Corticotropina, Interações medicamentosas)

  • Fluid retention events were typically managed by supportive care measures that may include diuretics or short courses of steroids. (bula de Dasatinibe, Advertências e precauções)

  • Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (bula de Docetaxel, Advertências e precauções)

  • DronedaronaantiarrítmicoLeve

    Hypokalemia and Hypomagnesemia with Potassium-Depleting Diuretics Hypokalemia or hypomagnesemia may occur with concomitant administration of potassium-depleting diuretics. (bula de Dronedarona, Advertências e precauções)

  • In addition to discontinuation of the drug, diuretic therapy may be required. (bula de Estrogênios esterificados + metiltestosterona, Advertências)

  • Finasteridainibidor da 5-alfa-redutaseLeve

    …clinical studies with acetaminophen, acetylsalicylic acid, α-blockers, angiotensin-converting enzyme (ACE) inhibitors, analgesics, anti-convulsants, beta-adrenergic blocking agents, diuretics, calcium channel blockers, cardiac nitrates, HMG-CoA reductase inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, H 2 antagonists and quinolone anti-infectives… (bula de Finasterida, Interações medicamentosas)

  • FlecainidaantiarrítmicoLeve

    Flecainide acetate has been used in a large number of patients receiving diuretics without apparent interaction. (bula de Flecainida, Interações medicamentosas)

  • Drugs that may cause hypercalcemia: Vitamin D, vitamin A, thiazide diuretics, estrogen, calcipotriene and teriparatide administration may cause hypercalcemia. (bula de Gliconato de cálcio, Interações medicamentosas)

  • Imatinibeinibidor da CYP3A4Leve

    Weigh patients regularly and manage unexpected rapid weight gain by drug interruption and diuretics. (bula de Imatinibe, Advertências e precauções)

  • Postmarketing cases of edema and fluid retention occurring within weeks of starting OPSUMIT, some requiring intervention with a diuretic or hospitalization for decompensated heart failure, have been reported [see Adverse Reactions (6.2) ] . (bula de Macitentana, Advertências e precauções)

  • Urine pH is altered by diet, drugs (e.g. carbonic anhydrase inhibitors, sodium bicarbonate) and clinical state of the patient (e.g. renal tubular acidosis or severe infections of the urinary tract). (bula de Memantina, Interações medicamentosas)

  • Memantina + donepezilainibidor da colinesteraseLeve

    Urine pH is altered by diet, drugs (e.g., carbonic anhydrase inhibitors, sodium bicarbonate) and clinical state of the patient (e.g., renal tubular acidosis or severe infections of the urinary tract). (bula de Memantina + donepezila, Interações medicamentosas)

  • MetenaminaantibióticoLeve

    Acetazolamide may prevent the urinary antiseptic effect of methenamine. (bula de Acetazolamida, Interações medicamentosas)

  • MetilprednisolonacorticosteroideLeve

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (bula de Metilprednisolona, Interações medicamentosas)

  • MetiltestosteronaandrogênioLeve

    In addition to discontinuation of the drug, diuretic therapy may be required. (bula de Metiltestosterona, Advertências)

  • PentoxifilinametilxantinaLeve

    Pentoxifylline extended-release tablets have been used concurrently with antihypertensive drugs, beta blockers, digitalis, diuretics, and antiarrhythmics, without observed problems. (bula de Pentoxifilina, Interações medicamentosas)

  • Piperacilina + tazobactamantibiótico da classe das penicilinasLeve

    Periodic electrolyte determinations should be performed in patients with low potassium reserves, and the possibility of hypokalemia should be kept in mind with patients who have potentially low potassium reserves and who are receiving cytotoxic therapy or diuretics. (bula de Piperacilina + tazobactam, Advertências e precauções)

  • PrednisolonacorticosteroideLeve

    Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisolona, Interações medicamentosas)

  • PrednisonacorticosteroideLeve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • SulfadiazinasulfonamidaLeve

    Potentiation of the action of sulfonylurea hypoglycemic agents, thiazide diuretics and uricosuric agents may also be noted. (bula de Sulfadiazina, Interações medicamentosas)

  • Sulfadiazina de pratasulfonamidaLeve

    There is a potential cross-sensitivity between silver sulfadiazine and other sulfonamides. (bula de Sulfadiazina de prata, Advertências e precauções)

  • TerbinafinaantifúngicoLeve

    There is no information available from adequate drug-drug interaction studies with the following classes of drugs: oral contraceptives, hormone replacement therapies, hypoglycemics, phenytoins, thiazide diuretics, and calcium channel blockers. (bula de Terbinafina, Interações medicamentosas)

  • TriancinolonacorticosteroideLeve

    Amphotericin B injection and potassium-depleting agents: When corticosteroids are administered concomitantly with potassium-depleting agents ( i.e., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (bula de Triancinolona, Interações medicamentosas)

Nenhuma interação significativa relatada (3)

  • BisoprololbetabloqueadorSem interação

    Pharmacokinetic studies document no clinically relevant interactions with other agents given concomitantly, including thiazide diuretics and cimetidine. (bula de Bisoprolol, Interações medicamentosas)

  • MexiletinaantiarrítmicoSem interação

    ECG intervals (PR, QRS, and QT) were not affected by concurrent mexiletine and digoxin, diuretics, or propranolol. (bula de Mexiletina, Interações medicamentosas)

  • PamidronatobisfosfonatoSem interação

    Loop Diuretics Concomitant administration of a loop diuretic had no effect on the calcium-lowering action of pamidronate disodium. (bula de Pamidronato, Interações medicamentosas)

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