Interações de Doxiciclina
Doxiciclina (Vibramycin, Doryx, Oracea), antibiótico da classe das tetraciclinas, tem 114 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 16; moderadas: 65; leves: 30; casos em que uma bula relata não haver interação significativa: 3). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.
Interações segundo a bula
Interações graves (16)
Since both acitretin and tetracyclines can cause increased intracranial pressure, their combined use is contraindicated (see WARNINGS: Pseudotumor Cerebri ). (bula de Acitretina, Contraindicações)
Avoid co-administration of tetracyclines with penicillin. (bula de Doxiciclina, Interações medicamentosas)
Avoid co-administration of tetracyclines with penicillin. (bula de Doxiciclina, Interações medicamentosas)
Avoid co-administration of tetracyclines with penicillin. (bula de Doxiciclina, Interações medicamentosas)
Avoid co-administration of tetracyclines with penicillin. (bula de Doxiciclina, Interações medicamentosas)
Avoid co-administration of tetracyclines with penicillin. (bula de Doxiciclina, Interações medicamentosas)
…Glimepiride Levofloxacin Losartan Metoprolol Pravastatin Propranolol Sitagliptin Warfarin Oral drugs that have to be separated from Ferric Citrate Tablets and meals Dosing Recommendations Doxycycline Take at least 1 hour before ferric citrate tablets Ciprofloxacin Take at least 2 hours before or after ferric citrate tablets Oral medications not listed in Table 2 There… (bula de Citrato férrico, Interações medicamentosas)
Avoid co-administration of tetracyclines with penicillin. (bula de Doxiciclina, Interações medicamentosas)
Avoid co-administration of tetracyclines with penicillin. (bula de Doxiciclina, Interações medicamentosas)
Concomitant use of isotretinoin and doxycycline hyclate should be avoided because isotretinoin is also known to cause pseudotumor cerebri. (bula de Doxiciclina, Advertências e precauções)
Avoid co-administration of tetracyclines with penicillin. (bula de Doxiciclina, Interações medicamentosas)
Avoid co-administration of tetracyclines with penicillin. (bula de Doxiciclina, Interações medicamentosas)
Avoid co-administration of tetracyclines with penicillin. (bula de Doxiciclina, Interações medicamentosas)
Doxycycline Administered with rifampin (10 mg/kg daily) Decrease exposure Irinotecan Administered with an antibiotic regimen including rifampin (450 mg/day), isoniazid (300 mg/day), and streptomycin (0.5 g/day) IM Prevention or Management: Avoid the use of rifampin, a strong CYP3A4 inducer, if possible. (bula de Rifampicina, Interações medicamentosas)
Doxycycline hyclate are contraindicated in persons who have shown hypersensitivity to any of the tetracyclines. (bula de Doxiciclina, Contraindicações)
Doxycycline hyclate are contraindicated in persons who have shown hypersensitivity to any of the tetracyclines. (bula de Doxiciclina, Contraindicações)
Interações moderadas (65)
Calcium acetate capsules may decrease the bioavailability of tetracyclines or fluoroquinolones via this mechanism. (bula de Acetato de cálcio, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Doxiciclina, Interações medicamentosas)
Patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Doxiciclina, Interações medicamentosas)
• Concomitant administration of tetracycline reduces atovaquone concentrations; use caution when coadministering. (bula de Atovaquona, Interações medicamentosas)
• Tetracycline may reduce atovaquone concentrations; parasitemia should be closely monitored. (bula de Atovaquona + proguanil, Interações medicamentosas)
Patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates, carbamazepine and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates, carbamazepine and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates, carbamazepine and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates, carbamazepine and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates, carbamazepine and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
O cálcio se liga a esses medicamentos no intestino e pode reduzir drasticamente a quantidade absorvida; separe as doses. (NIH Office of Dietary Supplements, Calcium)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates, carbamazepine and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
The absorption of tetracycline, furosemide, penicillin G, hydrochlorothiazide, and gemfibrozil was significantly decreased when given simultaneously with colestipol hydrochloride; these drugs were not tested to determine the effect of administration one hour before colestipol hydrochloride. (bula de Colestipol, Interações medicamentosas)
Drug Interactions Cholestyramine for Oral Suspension USP may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics (acidic), or propranolol (basic), as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins, and digitalis. (bula de Colestiramina, Interações medicamentosas)
Patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Doxiciclina, Interações medicamentosas)
Patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates, carbamazepine and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates, carbamazepine and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates, carbamazepine and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
O ferro se liga a esses medicamentos no intestino e reduz a sua absorção; separe as doses. (NIH Office of Dietary Supplements, Iron)
Patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
…antagonists, fibrates, propoxyphene, pentoxifylline, somatostatin analogs, anabolic steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides,… (bula de Glimepirida, Interações medicamentosas)
Patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Examples of relevant classes of compounds where antacids have been demonstrated to reduce bioavailability include antibiotics (such as quinolones, ampicillin, and tetracyclines), thyroid hormones, ACE inhibitors, statin lipid regulators, and anti-malarials. (bula de Lantânio, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
- LomitapidaModerada
Caution should be exercised when JUXTAPID is used with other medications known to have potential for hepatotoxicity, such as isotretinoin, amiodarone, acetaminophen (>4 g/day for ≥3 days/week), methotrexate, tetracyclines, and tamoxifen. (bula de Lomitapida, Advertências e precauções)
Suplementos e antiácidos que contêm magnésio reduzem a absorção desses medicamentos; separe as doses em pelo menos duas horas. (NIH Office of Dietary Supplements, Magnesium)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates, carbamazepine and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
…antagonists, fibrates, propoxyphene, pentoxifylline, somatostatin analogs, anabolic steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides,… (bula de Pioglitazona + glimepirida, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates, carbamazepine and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Tetracycline and other drugs that interact with magnesium Simultaneous administration of tetracycline with quinapril hydrochloride reduced the absorption of tetracycline by approximately 28% to 37%, possibly due to the high magnesium content in quinapril tablets. (bula de Quinapril, Interações medicamentosas)
Although tetracycline may be concomitantly administered with quinine sulfate, patients should be monitored closely for adverse reactions associated with quinine sulfate. (bula de Quinina, Interações medicamentosas)
…Adjustment May be Necessary Drug Class Examples of Drugs Within Class Antiarrhythmics Disopyramide, mexiletine, quinidine, tocainide Antibiotics Chloramphenicol, clarithromycin, dapsone, doxycycline; Fluoroquinolones (such as ciprofloxacin) Oral Anticoagulants Warfarin Anticonvulsants Phenytoin Antimalarials Quinine Azole Antifungals Fluconazole, itraconazole, ketoconazole… (bula de Rifapentina, Interações medicamentosas)
Patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Doxiciclina, Interações medicamentosas)
Antibiotics Drugs which may enhance the neuromuscular blocking action of nondepolarizing agents such as Rocuronium Bromide Injection include certain antibiotics (e.g., aminoglycosides; vancomycin; tetracyclines; bacitracin; polymyxins; colistin; and sodium colistimethate). (bula de Rocurônio, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
- SucralfatoModerada
Drug Interactions Some studies have shown that simultaneous sucralfate administration in healthy volunteers reduced the extent of absorption (bioavailability) of single doses of the following: cimetidine, digoxin, fluoroquinolone antibiotics, ketoconazole, l-thyroxine, phenytoin, quinidine, ranitidine, tetracycline, and theophylline. (bula de Sucralfato, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
The concomitant use of other products (e.g., tetracyclines) that can cause intracranial hypertension may increase the risk. (bula de Tretinoína, Advertências e precauções)
Patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Doxiciclina, Interações medicamentosas)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
O zinco reduz a absorção dos antibióticos das classes das quinolonas e das tetraciclinas; tome o antibiótico pelo menos duas horas antes ou quatro a seis horas depois do zinco. (NIH Office of Dietary Supplements, Zinc)
Barbiturates and Anti-Epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. (bula de Doxiciclina, Interações medicamentosas)
Menções leves (30)
Absorption of tetracyclines, including doxycycline hyclate is impaired by antacids containing aluminum, calcium, or magnesium, bismuth subsalicylate and iron-containing preparations. (bula de Doxiciclina, Interações medicamentosas)
Absorption of tetracyclines, including doxycycline hyclate is impaired by antacids containing aluminum, calcium, or magnesium, bismuth subsalicylate and iron-containing preparations. (bula de Doxiciclina, Interações medicamentosas)
Absorption of tetracyclines, including doxycycline hyclate is impaired by antacids containing aluminum, calcium, or magnesium, bismuth subsalicylate and iron-containing preparations. (bula de Doxiciclina, Interações medicamentosas)
Absorption of tetracyclines, including doxycycline hyclate is impaired by antacids containing aluminum, calcium, or magnesium, bismuth subsalicylate and iron-containing preparations. (bula de Doxiciclina, Interações medicamentosas)
WARNINGS DEMECLOCYCLINE HYDROCHLORIDE, LIKE OTHER TETRACYCLINE-CLASS ANTIBIOTICS, CAN CAUSE FETAL HARM WHEN ADMINISTERED TO A PREGNANT WOMAN. (bula de Demeclociclina, Advertências)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Absorption of tetracyclines, including doxycycline hyclate is impaired by antacids containing aluminum, calcium, or magnesium, bismuth subsalicylate and iron-containing preparations. (bula de Doxiciclina, Interações medicamentosas)
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective. (bula de Doxiciclina, Interações medicamentosas)
Absorption of tetracyclines, including doxycycline hyclate is impaired by antacids containing aluminum, calcium, or magnesium, bismuth subsalicylate and iron-containing preparations. (bula de Doxiciclina, Interações medicamentosas)
The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (bula de Vecurônio, Precauções)
Nenhuma interação significativa relatada (3)
…omeprazole prednisone, prednisolone ranitidine rifabutin roxithromycin sorbitol (purgative doses do not inhibit theophylline absorption) sucralfate terbutaline, systemic terfenadine tetracycline tocainide The Effect of Other Drugs on Theophylline Serum Concentration Measurements: Most serum theophylline assays in clinical use are immunoassays which are specific… (bula de Aminofilina, Interações medicamentosas)
…additional doses of Cisatracurium Besylate Injection, and to determine whether adjustments need to be made to the dose with subsequent administration. † Examples: aminoglycosides, tetracyclines, bacitracin, polymyxins, lincomycin, clindamycin, colistin, sodium colistimethate Drug or Drug Class Clinical Implications * Succinylcholine The use of succinylcholine… (bula de Cisatracúrio, Interações medicamentosas)
…ranitidine famotidine rifabutin felodipine roxithromycin finasteride Sorbitol (purgative doses do not inhibit hydrocortisone theophylline absorption) isoflurane sucralfate isoniazid terbutaline, systemic isradipine terfenadine influenza vaccine tetracycline ketoconazole tocainide lomefloxacin * Refer to PRECAUTIONS , Drug Interactions for information regarding table. (bula de Teofilina, Interações medicamentosas)
Verifique Doxiciclina com tudo o que você toma. Adicione sua lista completa; todos os pares são verificados de uma vez.
Abrir no verificadorNão é aconselhamento médico. A gravidade reflete a redação da bula, não as suas circunstâncias. Um alerta “grave” pode ser rotina sob supervisão, e um “leve” pode ser importante em doses altas. Pergunte a um farmacêutico.