Interações de Prednisona

Prednisona (Deltasone, Rayos), corticosteroide, tem 411 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 30; moderadas: 294; leves: 85; casos em que uma bula relata não haver interação significativa: 2). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.

A prednisona (Deltasone, Rayos) é um corticosteroide, uma versão sintética de um hormônio que as glândulas suprarrenais produzem. Ela reduz a inflamação e atenua o sistema imunológico. É usada para muitas condições, incluindo artrite, lúpus, alergias graves, crises de asma, doenças de pele, alguns cânceres e níveis baixos de corticosteroide natural. É apresentada em comprimidos, em um comprimido de liberação retardada e em líquidos, e geralmente é tomada com alimentos, uma a quatro vezes ao dia ou em dias alternados. As doses variam de 5 mg a 60 mg por dia, dependendo da condição.

Interações segundo a bula

Interações graves (30)

  • Abirateronainibidor da CYP2D6Grave

    At the primary analysis, increased incidences of fractures (28.6% vs 11.4%) and deaths (38.5% vs 35.5%) have been observed in patients who received abiraterone acetate plus a corticosteroid in combination with radium Ra 223 dichloride compared to patients who received placebo in combination with abiraterone acetate plus a corticosteroid. (bula de Abiraterona, Advertências e precauções)

  • AdalimumabeimunossupressorGrave

    Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (bula de Adalimumabe, Advertência em caixa preta)

  • Arformoterolagonista beta-adrenérgicoGrave

    Use of a LABA, including arformoterol tartrate inhalation solution, without an inhaled corticosteroid is contraindicated in patients with asthma. (bula de Arformoterol, Contraindicações)

  • AtazanavirantirretroviralGrave

    Coadministration of fluticasone propionate and REYATAZ with ritonavir is not recommended unless the potential benefit to the patient outweighs the risk of systemic corticosteroid side effects [see Warnings and Precautions (5.1) ] . (bula de Atazanavir, Interações medicamentosas)

  • Withhold INLYTA and avelumab or pembrolizumab, initiate corticosteroid therapy as needed, and/or permanently discontinue the combination for severe or life-threatening hepatotoxicity. (bula de Axitinibe, Advertências e precauções)

  • Baricitinibeinibidor da JAKGrave

    Most patients with rheumatoid arthritis who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (bula de Baricitinibe, Advertência em caixa preta)

  • Cetoconazolantifúngico azólicoGrave

    Fluticasone: Coadministration of fluticasone propionate and ketoconazole is not recommended unless the potential benefit to the patient outweighs the risk of systemic corticosteroid side effects. (bula de Cetoconazol, Interações medicamentosas)

  • Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (bula de Docetaxel, Advertências e precauções)

  • …(5.7) , Drug Interactions (7) , and Clinical Pharmacology (12.3) ]: Anticonvulsants: carbamazepine, oxcarbazepine, phenobarbital, phenytoin Antimycobacterials: rifampin, rifapentine Glucocorticoid (systemic): dexamethasone (more than a single-dose) Herbal Products: St John's wort ( Hypericum perforatum ) Proton Pump Inhibitors: e.g., dexlansoprazole, esomeprazole,… (bula de Entricitabina + rilpivirina + tenofovir, Contraindicações)

  • Epinefrina (adrenalina)simpaticomiméticoGrave

    …Antihistamines Thyroid hormones Diuretics Cardiac glycosides, such as digitalis glycosides Quinidine Drugs potentiating hypokalemic effects of epinephrine • Potassium depleting diuretics • Corticosteroids • Theophylline Epinephrine should not be used to counteract circulatory collapse or hypotension caused by phenothiazines, as a reversal of the pressor effects of epinephrine… (bula de Epinefrina (adrenalina), Interações medicamentosas)

  • EtanercepteimunossupressorGrave

    Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (bula de Etanercepte, Advertência em caixa preta)

  • Formoterolagonista beta-adrenérgicoGrave

    Use of a LABA, including formoterol fumarate inhalation solution, without an inhaled corticosteroid is contraindicated in patients with asthma [see Warnings and Precautions (5.1) ]. (bula de Formoterol, Contraindicações)

  • FosamprenavirantirretroviralGrave

    Coadministration of fluticasone and fosamprenavir calcium/ritonavir is not recommended unless the potential benefit to the patient outweighs the risk of systemic corticosteroid side effects. (bula de Fosamprenavir, Interações medicamentosas)

  • InfliximabeimunossupressorGrave

    Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (bula de Infliximabe, Advertência em caixa preta)

  • LovastatinaestatinaGrave

    Moreover, cholesterol and other products of the cholesterol biosynthesis pathway are essential components for fetal development, including synthesis of steroids and cell membranes. (bula de Lovastatina, Contraindicações)

  • Mifepristonainibidor da CYP3A4Grave

    WARNING: TERMINATION OF PREGNANCY Mifepristone is a potent antagonist of progesterone and cortisol via the progesterone and glucocorticoid (GR-II) receptors, respectively. (bula de Mifepristona, Advertência em caixa preta)

  • Mitotanoindutor da CYP3A4Grave

    If shock, severe trauma or infection occurs or develops, temporarily discontinue LYSODREN and administer exogenous steroids. (bula de Mitotano, Advertência em caixa preta)

  • Moexiprilinibidor da ECAGrave

    None of the cases were considered life-threatening and all resolved either without treatment or with medication (antihistamines or glucocorticoids). (bula de Moexipril, Advertências)

  • NevirapinaantirretroviralGrave

    Therefore, use of prednisone to prevent nevirapine-associated rash is not recommended. (bula de Nevirapina, Advertências e precauções)

  • RilpivirinaantirretroviralGrave

    Antimycobacterials Rifampin Rifapentine Glucocorticoid (systemic) Dexamethasone (more than a single-dose treatment) Herbal Products St. (bula de Rilpivirina, Contraindicações)

  • Salmeterolagonista beta-adrenérgicoGrave

    WARNING: ASTHMA-RELATED DEATH Long-acting beta 2 -adrenergic agonists (LABA), such as salmeterol, the active ingredient in SEREVENT DISKUS, as monotherapy (without inhaled corticosteroids [ICS]) increase the risk of asthma-related death. (bula de Salmeterol, Advertência em caixa preta)

  • SirolimoimunossupressorGrave

    In a multicenter clinical study, de novo renal transplant patients treated with sirolimus, mycophenolate mofetil (MMF), steroids, and an IL-2 receptor antagonist had significantly higher acute rejection rates and numerically higher death rates compared to patients treated with cyclosporine, MMF, steroids, and IL-2 receptor antagonist. (bula de Sirolimo, Advertências e precauções)

  • Intervention: Carefully adjust glucocorticoid dosing in pediatric patients receiving glucocorticoid treatments to avoid both hypoadrenalism and an inhibitory effect on growth. (bula de Somatropina, Interações medicamentosas)

  • TocilizumabeimunossupressorGrave

    Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (bula de Tocilizumabe, Advertência em caixa preta)

  • TofacitinibeimunossupressorGrave

    Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (bula de Tofacitinibe, Advertência em caixa preta)

  • Trandolaprilinibidor da ECAGrave

    Two of the four cases were life-threatening and resolved without treatment or with medication (corticosteroids). (bula de Trandolapril, Advertências)

  • TretinoínaretinoideGrave

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (bula de Tretinoína, Advertência em caixa preta)

  • Trióxido de arsêniomedicamento que prolonga o intervalo QTGrave

    If differentiation syndrome is suspected, immediately initiate high-dose corticosteroids and hemodynamic monitoring until resolution. (bula de Trióxido de arsênio, Advertência em caixa preta)

  • Umeclidínio + vilanterolanticolinérgicoGrave

    • use of a long-acting beta 2 -adrenergic agonist (LABA), including vilanterol, one of the active ingredients in Umeclidinium and Vilanterol ELLIPTA, without an inhaled corticosteroid (ICS), in patients with asthma [see Warnings and Precautions ( 5.1 )] . (bula de Umeclidínio + vilanterol, Contraindicações)

  • UpadacitinibeimunossupressorGrave

    Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (bula de Upadacitinibe, Advertência em caixa preta)

Interações moderadas (294)

  • AcarboseantidiabéticoModerada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • Ácido acetilsalicílico + dipiridamolantiagregante plaquetárioModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • Ácido mefenâmicoAINEModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • Ácido valproicoanticonvulsivanteModerada

    Oral Contraceptive Steroids Administration of a single-dose of ethinyloestradiol (50 mcg)/levonorgestrel (250 mcg) to 6 women on valproate (200 mg BID) therapy for 2 months did not reveal any pharmacokinetic interaction. (bula de Ácido valproico, Interações medicamentosas)

  • Ácido zoledrônicobisfosfonatoModerada

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (bula de Ácido zoledrônico, Advertências e precauções)

  • AclidínioanticolinérgicoModerada

    Sympathomimetics, Methylxanthines, Steroids In clinical studies, concurrent administration of aclidinium bromide and other drugs commonly used in the treatment of COPD including sympathomimetics (short-acting beta 2 agonists), methylxanthines, and oral and inhaled steroids showed no increases in adverse drug reactions. (bula de Aclidínio, Interações medicamentosas)

  • AfatinibeModerada

    Patients receiving concomitant corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDs) or anti-angiogenic agents, or patients with increasing age or who have an underlying history of gastrointestinal ulceration, underlying diverticular disease or bowel metastases may be at increased risk of perforation. (bula de Afatinibe, Advertências e precauções)

  • AlbendazolModerada

    Risk of Neurologic Symptoms: Neurocysticercosis patients may experience cerebral hypertensive episodes, seizures or focal neurologic deficits after initiation of therapy; begin appropriate steroid and anticonvulsant therapy. (bula de Albendazol, Advertências e precauções)

  • AlendronatobisfosfonatoModerada

    …osteonecrosis of the jaw include invasive dental procedures (e.g., tooth extraction, dental implants, boney surgery), diagnosis of cancer, concomitant therapies (e.g., chemotherapy, corticosteroids, angiogenesis inhibitors), poor oral hygiene, and co-morbid disorders (e.g., periodontal and/or other pre-existing dental disease, anemia, coagulopathy, infection, ill-fitting… (bula de Alendronato, Advertências e precauções)

  • AlentuzumabeimunossupressorModerada

    Institute appropriate medical management (e.g., glucocorticoids, epinephrine, meperidine) for infusion-related reactions as needed [see Dosage and Administration (2.2) ] . (bula de Alentuzumabe, Advertências e precauções)

  • Alisquirenoanti-hipertensivoModerada

    Patients who experience these effects, even without respiratory distress, require prolonged observation and appropriate monitoring measures since treatment with antihistamines and corticosteroids may not be sufficient to prevent respiratory involvement. (bula de Alisquireno, Advertências e precauções)

  • Alogliptinainibidor da DPP-4Moderada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Alogliptina + metforminainibidor da DPP-4Moderada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • AlpelisibeModerada

    If a SCAR is not confirmed, VIJOICE may require dose modifications, topical or systemic corticosteroids, or oral antihistamine treatment as described in Table 4 [see Dosage and Administration (2.5)] . (bula de Alpelisibe, Advertências e precauções)

  • AmiodaronaantiarrítmicoModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • Anfotericina BantifúngicoModerada

    Corticosteroids and Corticotropin (ACTH) Concurrent use of corticosteroids and ACTH may potentiate hypokalemia, which could predispose the patient to cardiac dysfunction. (bula de Anfotericina B, Interações medicamentosas)

  • ApixabanaanticoagulanteModerada

    Anticoagulant agents: May enhance or diminish anticoagulant effects. (bula de Prednisona, Interações medicamentosas)

  • Aprepitantoinibidor da CYP3A4Moderada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • ArgatrobanaanticoagulanteModerada

    Anticoagulant agents: May enhance or diminish anticoagulant effects. (bula de Prednisona, Interações medicamentosas)

  • Armodafinilaestimulante do SNCModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • AzatioprinaimunossupressorModerada

    In a detailed case report, 4 documented lymphopenia, diminished IgG and IgM levels, CMV infection, and a decreased thymic shadow were noted in an infant born to a mother receiving 150 mg azathioprine and 30 mg prednisone daily throughout pregnancy. (bula de Azatioprina, Advertências)

  • Azitromicinaantibiótico macrolídeoModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • BalsalazidasalicilatoModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • BeclometasonacorticosteroideModerada

    Hypercorticism and Adrenal Suppression QVAR REDIHALER will often help control asthma symptoms with less suppression of HPA function than therapeutically equivalent oral doses of prednisone. (bula de Beclometasona, Advertências e precauções)

  • Beladona + ópioopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Beladona + ópio, Advertências e precauções)

  • BendamustinaModerada

    Consider measures to prevent severe reactions, including antihistamines, antipyretics and corticosteroids in subsequent cycles in patients who have experienced Grade 1 or 2 infusion reactions. (bula de Bendamustina, Advertências e precauções)

  • • Reduction in Corticosteroid Dosage: Do not discontinue systemic or inhaled corticosteroids abruptly upon initiation of therapy with FASENRA. (bula de Benralizumabe, Advertências e precauções)

  • Bexagliflozinainibidor do SGLT2Moderada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Corticosteroids (systemic): cortisone/hydrocortisone dexamethasone ↑ corticosteroids (systemic) ↓ lenacapavir (dexamethasone) Concomitant administration with systemic corticosteroids whose exposures are significantly increased by CYP3A inhibitors can increase the risk for Cushing's syndrome and adrenal suppression. (bula de Bictegravir + entricitabina + tenofovir alafenamida, Interações medicamentosas)

  • BivalirudinaanticoagulanteModerada

    Anticoagulant agents: May enhance or diminish anticoagulant effects. (bula de Prednisona, Interações medicamentosas)

  • Bosentanaindutor da CYP3A4Moderada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • BudesonidacorticosteroideModerada

    Prednisone reduction can be accomplished by reducing the daily prednisone dose by 2.5 mg on a weekly basis during therapy with PULMICORT FLEXHALER. (bula de Budesonida, Advertências e precauções)

  • Budesonida + formoterolcorticosteroideModerada

    Prednisone reduction can be accomplished by reducing the daily prednisone dose by 2.5 mg on a weekly basis during therapy with budesonide and formoterol fumarate dihydrate. (bula de Budesonida + formoterol, Advertências e precauções)

  • BuprenorfinaopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Buprenorfina, Advertências e precauções)

  • If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Buprenorfina + naloxona, Advertências e precauções)

  • BupropionaantidepressivoModerada

    …risk of seizure: concomitant use of other medications that lower the seizure threshold (e.g., other bupropion products, antipsychotics, tricyclic antidepressants, theophylline, and systemic corticosteroids), metabolic disorders (e.g., hypoglycemia, hyponatremia, severe hepatic impairment, and hypoxia), or use of illicit drugs (e.g., cocaine) or abuse or misuse… (bula de Bupropiona, Advertências e precauções)

  • NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • Butalbital + paracetamolbarbitúricoModerada

    CYP 3A4 Inducers (e.g., Barbiturates, Phenytoin, Carbamazepine, and Rifampin) Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (bula de Prednisona, Interações medicamentosas)

  • CYP 3A4 Inducers (e.g., Barbiturates, Phenytoin, Carbamazepine, and Rifampin) Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (bula de Prednisona, Interações medicamentosas)

  • CYP 3A4 Inducers (e.g., Barbiturates, Phenytoin, Carbamazepine, and Rifampin) Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (bula de Prednisona, Interações medicamentosas)

  • ButorfanolopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Butorfanol, Advertências)

  • Canagliflozinainibidor do SGLT2Moderada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • CarbamazepinaanticonvulsivanteModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • CefoxitinacefalosporinaModerada

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (bula de Cefoxitina, Advertências e precauções)

  • CelecoxibeAINEModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • CenobamatoanticonvulsivanteModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • CetoprofenoAINEModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • CetorolacoAINEModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • CiclesonidacorticosteroideModerada

    Prednisone reduction can be accomplished by reducing the daily prednisone dose by 2.5 mg on a weekly basis during ALVESCO therapy [see Dosage and Administration ( 2 )] . (bula de Ciclesonida, Advertências e precauções)

  • CiclosporinaimunossupressorModerada

    Cyclosporine: Increase in activity of both, cyclosporine and corticosteroid when administered concurrently. (bula de Prednisona, Interações medicamentosas)

  • Cimetidinabloqueador H2Moderada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • CiprofloxacinofluoroquinolonaModerada

    The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (bula de Ciprofloxacino, Advertências e precauções)

  • CitarabinaantimetabólitoModerada

    Drug Interactions Reversible decreases in steady-state plasma digoxin concentrations and renal glycoside excretion were observed in patients receiving beta-acetyldigoxin and chemotherapy regimens containing cyclophosphamide, vincristine and prednisone with or without cytarabine injection or procarbazine. (bula de Citarabina, Interações medicamentosas)

  • CladribinaantimetabólitoModerada

    Prevention or Management Consider a possible decrease in cladribine efficacy if potent BCRP (e.g., corticosteroids) or P-gp (e.g., rifampicin, St. (bula de Cladribina, Interações medicamentosas)

  • Claritromicinaantibiótico macrolídeoModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • ClobazambenzodiazepínicoModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • Cocaínaanestésico localModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • CodeínaopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Codeína, Advertências e precauções)

  • Colestiraminasequestrante de ácidos biliaresModerada

    Cholestyramine Cholestyramine may increase the clearance of corticosteroids. (bula de Prednisona, Interações medicamentosas)

  • DabigatranaanticoagulanteModerada

    Anticoagulant agents: May enhance or diminish anticoagulant effects. (bula de Prednisona, Interações medicamentosas)

  • Dapagliflozinainibidor do SGLT2Moderada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Dapagliflozina + metforminainibidor do SGLT2Moderada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • DaptomicinaantibióticoModerada

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (bula de Daptomicina, Advertências e precauções)

  • DarunavirantirretroviralModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • Darunavir + cobicistateantirretroviralModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • Deferasiroxsuplemento de ferroModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • DenosumabeModerada

    Other risk factors for the development of ONJ include immunosuppressive therapy, treatment with angiogenesis inhibitors, systemic corticosteroids, diabetes, and gingival infections. (bula de Denosumabe, Advertências e precauções)

  • Desogestrel + etinilestradiolanticoncepcional oralModerada

    Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • DexametasonacorticosteroideModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • Diacetato de etinodiol + etinilestradiolanticoncepcional oralModerada

    Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • DicicloverinaanticolinérgicoModerada

    Anticholinergic drugs in the presence of increased intraocular pressure may be hazardous when taken concurrently with agents such as corticosteroids. (bula de Dicicloverina, Interações medicamentosas)

  • DiclofenacoAINEModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • DiflunisalAINEModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • Digoxinaglicosídeo digitálicoModerada

    Digitalis Patients on digitalis glycosides may be at increased risk of arrhythmias due to hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • Diltiazembloqueador dos canais de cálcioModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • DolutegravirantirretroviralModerada

    …following drugs can be coadministered with dolutegravir without a dose adjustment: atazanavir/ritonavir, darunavir/ritonavir, elbasvir/grazoprevir, methadone, midazolam, omeprazole, oral contraceptives containing norgestimate and ethinyl estradiol, prednisone, rifabutin, rilpivirine, sofosbuvir/velpatasvir, and tenofovir [see Clinical Pharmacology ( 12.3 )] . (bula de Dolutegravir, Interações medicamentosas)

  • …treated with 6-mercaptopurine (500 mg/m 2 intravenously daily for 5 days per cycle every 2–3 weeks) and doxorubicin hydrochloride (50 mg/m 2 intravenous once per cycle every 2–3 weeks) alone or with vincristine and prednisone, all developed hepatic dysfunction manifested by increased total serum bilirubin, alkaline phosphatase and aspartate aminotransferase. (bula de Doxorrubicina, Interações medicamentosas)

  • DronedaronaantiarrítmicoModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • Drospirenona + etinilestradiolanticoncepcional oralModerada

    Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • Dulaglutidaagonista do receptor de GLP-1Moderada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • DupilumabeModerada

    Eosinophilic Conditions: Be alert to vasculitic rash, worsening pulmonary symptoms, cardiac complications, kidney injury and/or neuropathy, especially upon reduction of oral corticosteroids. (bula de Dupilumabe, Advertências e precauções)

  • EdoxabanaanticoagulanteModerada

    Anticoagulant agents: May enhance or diminish anticoagulant effects. (bula de Prednisona, Interações medicamentosas)

  • EfavirenzantirretroviralModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • Efavirenz + lamivudina + tenofovirantirretroviralModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • EfedrinasimpaticomiméticoModerada

    CYP 3A4 Inducers (e.g., Barbiturates, Phenytoin, Carbamazepine, and Rifampin) Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (bula de Prednisona, Interações medicamentosas)

  • Although other risk factors were present in some cases (such as corticosteroid use, exposure to radiation), a possible risk attributable to treatment with ivacaftor cannot be excluded. (bula de Elexacaftor + tezacaftor + ivacaftor, Advertências e precauções)

  • CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • Empagliflozinainibidor do SGLT2Moderada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Empagliflozina + metforminainibidor do SGLT2Moderada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • EnoxaparinaanticoagulanteModerada

    Anticoagulant agents: May enhance or diminish anticoagulant effects. (bula de Prednisona, Interações medicamentosas)

  • Eritromicinaantibiótico macrolídeoModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • ErlotinibeModerada

    Patients receiving concomitant anti-angiogenic agents, corticosteroids, NSAIDs, or taxane-based chemotherapy, or who have prior history of peptic ulceration or diverticular disease may be at increased risk of perforation [see Adverse Reactions (6.1 , 6.2) ]. (bula de Erlotinibe, Advertências e precauções)

  • EslicarbazepinaanticonvulsivanteModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • EstradiolestrogênioModerada

    Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • Estradiol + dienogesteanticoncepcional oralModerada

    Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • Estradiol + noretisteronaestrogênioModerada

    Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • Estrogênios conjugadosestrogênioModerada

    Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • EtodolacoAINEModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • EtravirinaantirretroviralModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • EverolimoimunossupressorModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • Exenatidaagonista do receptor de GLP-1Moderada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Use of corticosteroids may cause a protein catabolic state and, thereby, potentially increase plasma ammonia levels in patients with impaired ability to form urea. (bula de Fenilacetato de sódio + benzoato de sódio, Interações medicamentosas)

  • Corticosteroids, valproic acid, or haloperidol : May increase plasma ammonia level; monitor ammonia levels closely. (bula de Fenilbutirato de glicerol, Interações medicamentosas)

  • Valproic Acid, Haloperidol, or Corticosteroids : May increase plasma ammonia level; monitor ammonia levels closely. (bula de Fenilbutirato de sódio, Interações medicamentosas)

  • FenilefrinadescongestionanteModerada

    Agonistic Effects (increase in BIORPHEN blood pressure effect) can occur with monoamine oxidase inhibitors (MAOI), oxytocin and oxytocic drugs, tricyclic antidepressants, angiotensin and aldosterone, atropine, steroids, norepinephrine transporter inhibitors, ergot alkaloids. (bula de Fenilefrina, Interações medicamentosas)

  • FenitoínaanticonvulsivanteModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • FenobarbitalbarbitúricoModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • CYP 3A4 Inducers (e.g., Barbiturates, Phenytoin, Carbamazepine, and Rifampin) Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (bula de Prednisona, Interações medicamentosas)

  • FenoprofenoAINEModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • FentanilaopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Fentanila, Advertências e precauções)

  • Fentermina + topiramatoestimulante do SNCModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • Fidaxomicinaantibiótico macrolídeoModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • FingolimodeimunossupressorModerada

    In both cases, the patients were taking a 1.25 mg dose of fingolimod (higher than the recommended 0.5 mg dose) and had received high-dose corticosteroid therapy to treat suspected MS relapses. (bula de Fingolimode, Advertências e precauções)

  • Fluconazolantifúngico azólicoModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • FlunisolidacorticosteroideModerada

    The use of flunisolide with alternate-day prednisone systemic treatment could increase the likelihood of HPA suppression compared to a therapeutic dose of either one alone. (bula de Flunisolida, Advertências)

  • FluocinonidacorticosteroideModerada

    Use of more than one corticosteroid-containing product at the same time may increase the total systemic absorption of topical corticosteroids. (bula de Fluocinonida, Advertências e precauções)

  • FlurbiprofenoAINEModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • FluticasonacorticosteroideModerada

    Prednisone reduction can be accomplished by reducing the daily prednisone dose by 2.5 mg on a weekly basis during therapy with Fluticasone Propionate DISKUS. (bula de Fluticasona, Advertências e precauções)

  • Fluticasona + salmeterolcorticosteroideModerada

    Hypercorticism and Adrenal Suppression Fluticasone propionate, a component of Fluticasone Propionate/Salmeterol MDPI, will often help control asthma symptoms with less suppression of HPA function than therapeutically equivalent oral doses of prednisone. (bula de Fluticasona + salmeterol, Advertências e precauções)

  • FondaparinuxanticoagulanteModerada

    Anticoagulant agents: May enhance or diminish anticoagulant effects. (bula de Prednisona, Interações medicamentosas)

  • Fosaprepitantoinibidor da CYP3A4Moderada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • FosfenitoínaanticonvulsivanteModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • FulvestrantoestrogênioModerada

    Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • GlibenclamidasulfonilureiaModerada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Glibenclamida + metforminasulfonilureiaModerada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • GlimepiridasulfonilureiaModerada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • GlipizidasulfonilureiaModerada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Glipizida + metforminasulfonilureiaModerada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • GriseofulvinaantifúngicoModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • HalobetasolcorticosteroideModerada

    Use of more than one corticosteroid-containing product at the same time may increase the total systemic exposure to topical corticosteroids. (bula de Halobetasol, Advertências e precauções)

  • HaloperidolantipsicóticoModerada

    Caution is advised when haloperidol decanoate is used in combination with drugs known to cause electrolyte imbalance (e.g., diuretics or corticosteroids) because hypokalemia, hypomagnesemia, and hypocalcemia are risk factors for QT prolongation. (bula de Haloperidol, Interações medicamentosas)

  • HeparinaanticoagulanteModerada

    Anticoagulant agents: May enhance or diminish anticoagulant effects. (bula de Prednisona, Interações medicamentosas)

  • HidralazinavasodilatadorModerada

    Long-term treatment with steroids may be necessary (see PRECAUTIONS, Laboratory Tests ). (bula de Hidralazina, Advertências)

  • HidrocodonaopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Hidrocodona, Advertências e precauções)

  • If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Hidrocodona + clorfeniramina, Advertências e precauções)

  • If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Hidrocodona + homatropina, Advertências e precauções)

  • NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Hidrocodona + paracetamol, Advertências)

  • HidromorfonaopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Hidromorfona, Advertências e precauções)

  • IbandronatobisfosfonatoModerada

    …osteonecrosis of the jaw include invasive dental procedures (e.g., tooth extraction, dental implants, boney surgery), diagnosis of cancer, concomitant therapies (e.g., chemotherapy, corticosteroids, angiogenesis inhibitors), poor oral hygiene, and co-morbid disorders (e.g., periodontal and/or other pre-existing dental disease, anemia, coagulopathy, infection, ill-fitting… (bula de Ibandronato, Advertências e precauções)

  • IbuprofenoAINEModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • Imatinibeinibidor da CYP3A4Moderada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • IndometacinaAINEModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • Insulina asparteinsulinaModerada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Insulina degludecainsulinaModerada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Insulina detemirinsulinaModerada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Insulina glarginainsulinaModerada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Insulina lisproinsulinaModerada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • IsoniazidaantibióticoModerada

    Antitubercular Drugs Serum concentrations of isoniazid may be decreased. (bula de Prednisona, Interações medicamentosas)

  • Itraconazolantifúngico azólicoModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • Ivacaftorinibidor da CYP3A4Moderada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • IvermectinaModerada

    Oral hydration, recumbency, intravenous normal saline, and/or parenteral corticosteroids have been used to treat postural hypotension. (bula de Ivermectina, Advertências)

  • LenacapavirantirretroviralModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • LevofloxacinofluoroquinolonaModerada

    The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients usually over 60 years of age, in those taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (bula de Levofloxacino, Advertências e precauções)

  • LevonorgestrelprogestinaModerada

    Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • Levonorgestrel + etinilestradiolanticoncepcional oralModerada

    Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • LevorfanolopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Levorfanol, Advertências)

  • Levossalbutamolagonista beta-adrenérgicoModerada

    If the patient needs more doses of XOPENEX HFA than usual, this may be a marker of destabilization of asthma and requires reevaluation of the patient and treatment regimen, giving special consideration to the possible need for anti-inflammatory treatment, e.g., corticosteroids. (bula de Levossalbutamol, Advertências e precauções)

  • Levotiroxinahormônio tireoidianoModerada

    Changes in thyroid status of the patient may necessitate adjustment in dosage. (bula de Prednisona, Advertências e precauções)

  • Levotiroxina + liotironinahormônio tireoidianoModerada

    Changes in thyroid status of the patient may necessitate adjustment in dosage. (bula de Prednisona, Advertências e precauções)

  • Linagliptinainibidor da DPP-4Moderada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Linagliptina + metforminainibidor da DPP-4Moderada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Liotironinahormônio tireoidianoModerada

    Changes in thyroid status of the patient may necessitate adjustment in dosage. (bula de Prednisona, Advertências e precauções)

  • Liraglutidaagonista do receptor de GLP-1Moderada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Lisinopril + hidroclorotiazidainibidor da ECAModerada

    Even in those instances where swelling of only the tongue is involved, without respiratory distress, patients may require prolonged observation since treatment with antihistamines and corticosteroids may not be sufficient. (bula de Lisinopril + hidroclorotiazida, Advertências)

  • Lopinavir + ritonavirantirretroviralModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • Lorlatinibeindutor da CYP3A4Moderada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • In patients who experience mild or moderate IRRs, consider premedications, including antihistamines, corticosteroids, and antipyretics. (bula de Margetuximabe, Advertências e precauções)

  • MedroxiprogesteronaprogestinaModerada

    Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • MegestrolprogestinaModerada

    Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • MeloxicamAINEModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • MepolizumabeModerada

    Decrease corticosteroids gradually, if appropriate. (bula de Mepolizumabe, Advertências e precauções)

  • MesalazinasalicilatoModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • MetadonaopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Metadona, Advertências e precauções)

  • Metazolamidainibidor da anidrase carbônicaModerada

    Drug Interactions Methazolamide should be used with caution in patients on steroid therapy because of the potential for developing hypokalemia. (bula de Metazolamida, Interações medicamentosas)

  • MetforminabiguanidaModerada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Metildopaanti-hipertensivoModerada

    If not, corticosteroids may be given and other causes of anemia should be considered. (bula de Metildopa, Advertências)

  • MetiltestosteronaandrogênioModerada

    Testosterone has been subject to abuse, typically at doses higher than recommended for the approved indication and in combination with other anabolic androgenic steroids. (bula de Metiltestosterona, Advertências)

  • MetiraponaModerada

    This can be corrected by giving appropriate doses of corticosteroids. (bula de Metirapona, Advertências e precauções)

  • MetoexitalbarbitúricoModerada

    CYP 3A4 Inducers (e.g., Barbiturates, Phenytoin, Carbamazepine, and Rifampin) Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (bula de Prednisona, Interações medicamentosas)

  • Metolazonadiurético tiazídicoModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (bula de Metolazona, Interações medicamentosas)

  • MetotrexatoimunossupressorModerada

    NSAIDs, Aspirin, and Steroids: May elevate and prolong serum methotrexate levels and increase gastrointestinal toxicity. (bula de Metotrexato, Interações medicamentosas)

  • MiglitolantidiabéticoModerada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Mirabegronaagonista beta-adrenérgicoModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • Mitapivateindutor da CYP3A4Moderada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • MitoxantronaModerada

    In a randomized comparative trial of mitoxantrone injection plus low-dose prednisone vs. low-dose prednisone, 7 of 128 patients (5.5 %) treated with mitoxantrone injection had a cardiac event defined as any decrease in LVEF below the normal range, congestive heart failure (n = 3), or myocardial ischemia. (bula de Mitoxantrona, Advertências)

  • Modafinilaestimulante do SNCModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • MometasonacorticosteroideModerada

    Hypercorticism and Adrenal Suppression ASMANEX HFA will often help control asthma symptoms with less suppression of HPA function than therapeutically equivalent oral doses of prednisone. (bula de Mometasona, Advertências e precauções)

  • Montelucasteantagonista do receptor de leucotrienosModerada

    Inhaled corticosteroid may be reduced gradually. (bula de Montelucaste, Advertências e precauções)

  • MorfinaopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Morfina, Advertências e precauções)

  • MoxifloxacinofluoroquinolonaModerada

    The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (bula de Moxifloxacino, Advertências e precauções)

  • NabumetonaAINEModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • Nafcilinaantibiótico da classe das penicilinasModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • NalbufinaopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Nalbufina, Advertências)

  • Naltrexona + bupropionaantagonista opioideModerada

    …hypoglycemia concomitant administration of medications that may lower the seizure threshold, including other bupropion products, antipsychotics, tricyclic antidepressants, theophylline, systemic steroids Recommendations for Reducing the Risk of Seizure: Clinical experience with bupropion suggests that the risk of seizure may be minimized by adhering to the recommended… (bula de Naltrexona + bupropiona, Advertências e precauções)

  • NaproxenoAINEModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • NatalizumabeimunossupressorModerada

    In Studies MS1 and MS2, an increase in infections was seen in patients concurrently receiving short courses of corticosteroids. (bula de Natalizumabe, Advertências e precauções)

  • NateglinidameglitinidaModerada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • NefazodonaantidepressivoModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • NintedanibeModerada

    Use OFEV with caution when treating patients with recent abdominal surgery, previous history of diverticular disease or receiving concomitant corticosteroids or NSAIDs. (bula de Nintedanibe, Advertências e precauções)

  • Nirmatrelvir + ritonavirantiviralModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • NoretisteronaprogestinaModerada

    Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • Noretisterona + etinilestradiolanticoncepcional oralModerada

    Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • Norgestimato + etinilestradiolanticoncepcional oralModerada

    Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • Norgestrel + etinilestradiolanticoncepcional oralModerada

    Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • OcrelizumabeimunossupressorModerada

    In multiple sclerosis (MS) clinical trials, all adult and pediatric patients who were treated with OCREVUS received premedication with methylprednisolone (or an equivalent steroid), and may have also received an antihistamine (all pediatric patients) and/or an analgesic/antipyretic to reduce the risk of infusion reactions prior to each infusion. (bula de Ocrelizumabe, Advertências e precauções)

  • OfloxacinofluoroquinolonaModerada

    The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients over 60 years of age, in those taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (bula de Ofloxacino, Advertências)

  • OliceridinaopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Oliceridina, Advertências e precauções)

  • OmalizumabeModerada

    Corticosteroid Reduction: Do not abruptly discontinue corticosteroids upon initiation of OMLYCLO therapy. (bula de Omalizumabe, Advertências e precauções)

  • NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • OxaprozinaAINEModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • OxcarbazepinaanticonvulsivanteModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • OxicodonaopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Oxicodona, Advertências e precauções)

  • If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Oxicodona + paracetamol, Advertências e precauções)

  • OximorfonaopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Oximorfona, Advertências e precauções)

  • Palbociclibeinibidor da CYP3A4Moderada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • PamidronatobisfosfonatoModerada

    Many of these patients were also receiving chemotherapy and corticosteroids, which may be risk factors for ONJ. (bula de Pamidronato, Advertências e precauções)

  • Paracetamol + codeínaopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Paracetamol + codeína, Advertências)

  • NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • PasireotidaModerada

    If adrenal insufficiency is suspected, it should be confirmed and treated per standard of care with exogenous glucocorticoids at replacement doses . (bula de Pasireotida, Advertências e precauções)

  • PenicilaminaModerada

    Treatment has consisted of high doses of corticosteroids alone or, in some cases, concomitantly with an immunosuppressant. (bula de Penicilamina, Advertências)

  • Pentazocina + naloxonaopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Pentazocina + naloxona, Advertências)

  • PerampanelanticonvulsivanteModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • Petidina (meperidina)opioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Petidina (meperidina), Advertências e precauções)

  • PioglitazonatiazolidinedionaModerada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Pioglitazona + glimepiridatiazolidinedionaModerada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Pioglitazona + metforminatiazolidinedionaModerada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • PiroxicamAINEModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • PonesimodeimunossupressorModerada

    Prior and Concomitant Treatment with Anti-neoplastic, Immune-Modulating, or Immunosuppressive Therapies Anti-neoplastic, immune-modulating, or immunosuppressive therapies (including corticosteroids) should be coadministered with caution because of the risk of additive immune system effects [see Drug Interactions (7.1) ] . (bula de Ponesimode, Advertências e precauções)

  • Posaconazolantifúngico azólicoModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • PrednisolonacorticosteroideModerada

    Published animal studies show prednisolone to be teratogenic in rats, rabbits, hamsters, and mice with increased incidence of cleft palate in offspring. (bula de Prednisona, Advertências e precauções)

  • PrimidonaanticonvulsivanteModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • ProgesteronaprogestinaModerada

    Estrogens, Including Oral Contraceptives Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (bula de Prednisona, Interações medicamentosas)

  • Prometazina + codeínaopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Prometazina + codeína, Advertências e precauções)

  • Propiltiouracilamedicamento antitireoidianoModerada

    Changes in thyroid status of the patient may necessitate adjustment in dosage. (bula de Prednisona, Advertências e precauções)

  • Propofoldepressor do SNCModerada

    The following appear to be major risk factors for the development of these events: decreased oxygen delivery to tissues; serious neurological injury and/or sepsis; high dosages of one or more of the following pharmacological agents: vasoconstrictors, steroids, inotropes and/or prolonged, high-dose infusions of propofol (> 5 mg/kg/hour for > 48 hours). (bula de Propofol, Advertências e precauções)

  • Ranolazinamedicamento que prolonga o intervalo QTModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • RepaglinidameglitinidaModerada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • RifabutinaantibióticoModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • RifampicinaantibióticoModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • RifapentinaantibióticoModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • RisedronatobisfosfonatoModerada

    …the jaw include invasive dental procedures (for example, tooth extraction, dental implants, boney surgery), diagnosis of cancer, concomitant therapies (for example, chemotherapy, corticosteroids, angiogenesis inhibitors), poor oral hygiene, and co-morbid disorders (for example, periodontal and/or other pre-existing dental disease, anemia, coagulopathy, infection,… (bula de Risedronato, Advertências e precauções)

  • RitonavirantirretroviralModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • RivaroxabanaanticoagulanteModerada

    Anticoagulant agents: May enhance or diminish anticoagulant effects. (bula de Prednisona, Interações medicamentosas)

  • Rocurôniobloqueador neuromuscularModerada

    Therefore, for patients receiving both neuromuscular blocking agents (including Rocuronium Bromide Injection) and corticosteroids, the period of use of the neuromuscular blocking agent should be limited as much as possible and only used in the setting where in the opinion of the prescribing physician, the specific advantages of the drug outweigh the risk. (bula de Rocurônio, Advertências e precauções)

  • Salbutamolagonista beta-adrenérgicoModerada

    If the patient needs more doses of Albuterol Sulfate HFA than usual, this may be a marker of destabilization of asthma and requires reevaluation of the patient and treatment regimen, giving special consideration to the possible need for anti-inflammatory treatment, e.g., corticosteroids. (bula de Salbutamol, Advertências e precauções)

  • SalsalatoAINEModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • Saxagliptinainibidor da DPP-4Moderada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Saxagliptina + metforminainibidor da DPP-4Moderada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Semaglutidaagonista do receptor de GLP-1Moderada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Sitagliptinainibidor da DPP-4Moderada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Sitagliptina + metforminainibidor da DPP-4Moderada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • Subsalicilato de bismutosalicilatoModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • SulfassalazinasulfonamidaModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • SulindacoAINEModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • Sumatriptana + naproxenotriptanoModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • Suvorexantosedativo-hipnóticoModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • Suxametônio (succinilcolina)bloqueador neuromuscularModerada

    The neuromuscular blocking effect of succinylcholine may be enhanced by drugs that reduce plasma cholinesterase activity (e.g., chronically administered oral contraceptives, glucocorticoids, or certain monoamine oxidase inhibitors) or by drugs that irreversibly inhibit plasma cholinesterase [see Warnings and Precautions (5.9) ]. (bula de Suxametônio (succinilcolina), Interações medicamentosas)

  • Suzetriginaindutor da CYP3A4Moderada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • TacrolimoimunossupressorModerada

    Mild or Moderate CYP3A Inducers Methylprednisolone, prednisone May decrease tacrolimus whole blood trough concentrations. (bula de Tacrolimo, Interações medicamentosas)

  • TapentadolopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Tapentadol, Advertências e precauções)

  • TemozolomidaModerada

    Pneumocystis Pneumonia (PCP) : Closely monitor all patients, particularly those receiving steroids, for the development of lymphopenia and PCP. (bula de Temozolomida, Advertências e precauções)

  • TensirolimoModerada

    If ILD is suspected, discontinue TORISEL, and consider use of corticosteroids and/or antibiotics. (bula de Tensirolimo, Advertências e precauções)

  • TeofilinametilxantinaModerada

    Dosage Increases: Increases in the dose of theophylline should not be made in response to an acute exacerbation of symptoms of chronic lung disease since theophylline provides little added benefit to inhaled beta2 -selective agonists and systemically administered corticosteroids in this circumstance and increases the risk of adverse effects. (bula de Teofilina, Advertências)

  • Terbutalinaagonista beta-adrenérgicoModerada

    If the patient needs more doses of terbutaline sulfate tablets than usual, this may be a marker of destabilization of asthma and requires reevaluation of the patient and the treatment regimen, giving special consideration to the possible need for anti-inflammatory treatment, e.g., corticosteroids. (bula de Terbutalina, Advertências)

  • Teriparatidahormônio tireoidianoModerada

    Changes in thyroid status of the patient may necessitate adjustment in dosage. (bula de Prednisona, Advertências e precauções)

  • Glucocorticoids : Patients receiving glucocorticoid replacement for previously diagnosed hypoadrenalism may require an increase in maintenance or stress doses following initiation of EGRIFTA SV. (bula de Tesamorrelina, Interações medicamentosas)

  • TestosteronaandrogênioModerada

    Abuse of Testosterone and Monitoring of Serum Testosterone : If testosterone use at doses higher than recommended for the approved indication and in combination with other anabolic androgenic steroids is suspected, check serum testosterone concentration ( 5.5 ). (bula de Testosterona, Advertências e precauções)

  • Tiamazol (metimazol)medicamento antitireoidianoModerada

    Changes in thyroid status of the patient may necessitate adjustment in dosage. (bula de Prednisona, Advertências e precauções)

  • Ticagrelorantiagregante plaquetárioModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • TiotrópioanticolinérgicoModerada

    Concomitant Respiratory Medications SPIRIVA RESPIMAT has been used concomitantly with short-acting and long-acting sympathomimetic (beta-agonists) bronchodilators, methylxanthines, oral and inhaled steroids, antihistamines, mucolytics, leukotriene modifiers, cromones, and anti-IgE treatment without increases in adverse reactions. (bula de Tiotrópio, Interações medicamentosas)

  • Tirzepatidaagonista do receptor de GLP-1Moderada

    Antidiabetic agents: May increase blood glucose concentrations. (bula de Prednisona, Interações medicamentosas)

  • TolmetinaAINEModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • TopiramatoanticonvulsivanteModerada

    CYP 3A4 inducers and inhibitors: May, respectively, increase or decrease clearance of corticosteroids, necessitating dose adjustment. (bula de Prednisona, Interações medicamentosas)

  • Torasemidadiurético de alçaModerada

    Corticosteroids and ACTH: Increased risk of hypokalemia. (bula de Torasemida, Interações medicamentosas)

  • TramadolopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Tramadol, Advertências e precauções)

  • Tramadol + paracetamolopioideModerada

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (bula de Tramadol + paracetamol, Advertências e precauções)

  • TrastuzumabeModerada

    Interrupt TRAZIMERA infusion in all patients experiencing dyspnea, clinically significant hypotension, and intervention of medical therapy administered (which may include epinephrine, corticosteroids, diphenhydramine, bronchodilators, and oxygen). (bula de Trastuzumabe, Advertências e precauções)

  • Triantereno + hidroclorotiazidadiurético poupador de potássioModerada

    Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)

  • VarfarinaanticoagulanteModerada

    Anticoagulant agents: May enhance or diminish anticoagulant effects. (bula de Prednisona, Interações medicamentosas)

  • Verapamilbloqueador dos canais de cálcioModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • Voriconazolantifúngico azólicoModerada

    CYP 3A4 Inhibitors (e.g., Ketoconazole, Macrolide Antibiotics) Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to increased risk of corticosteroid side effects. (bula de Prednisona, Interações medicamentosas)

  • Prior to the first BIZENGRI infusion, premedicate with a corticosteroid, an H1 antihistamine and acetaminophen to reduce the risk of IRRs [see Dosage and Administration (2.4) ]. (bula de Zenocutuzumabe, Advertências e precauções)

Menções leves (85)

  • Acetazolamidainibidor da anidrase carbônicaLeve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • Ácido bempedoicoinibidor do OATP1B1Leve

    Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (bula de Ácido bempedoico, Advertências e precauções)

  • Ácido etacrínicodiurético de alçaLeve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • If signs of hypersensitivity occur, e.g. anaphylactoid reaction or angioedema develops, discontinue the Activase infusion and promptly institute appropriate therapy (e.g., antihistamines, intravenous corticosteroids, epinephrine). (bula de Alteplase, Advertências e precauções)

  • AmicacinaaminoglicosídeoLeve

    Most patients with hypersensitivity pneumonitis discontinued treatment with ARIKAYCE and received treatment with corticosteroids [see Adverse Reactions (6.1) ] . (bula de Amicacina, Advertências e precauções)

  • Amiloridadiurético poupador de potássioLeve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • Ampicilinaantibiótico da classe das penicilinasLeve

    OXYGEN, INTRAVENOUS STEROIDS, AND AIRWAY MANAGEMENT, INCLUDING INTUBATION, SHOULD ALSO BE ADMINISTERED AS INDICATED. (bula de Ampicilina, Advertências)

  • Anfetaminaestimulante do SNCLeve

    Drug/Laboratory Test Interactions Amphetamines can cause a significant elevation in plasma corticosteroid levels. (bula de Anfetamina, Interações medicamentosas)

  • Anfetamina + dextroanfetaminaestimulante do SNCLeve

    Interference with Laboratory Tests Amphetamines can cause a significant elevation in plasma corticosteroid levels. (bula de Anfetamina + dextroanfetamina, Interações medicamentosas)

  • Atenolol + clortalidonabetabloqueadorLeve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • Benzilpenicilina (penicilina G)antibiótico da classe das penicilinasLeve

    Oxygen, intravenous steroids, and airway management, including intubation, should also be administered as indicated. (bula de Benzilpenicilina (penicilina G), Advertências)

  • Discontinue in patients who develop a severe infusion-related reaction and administer appropriate medical therapy (e.g., epinephrine, corticosteroids, intravenous antihistamines, bronchodilators and/or oxygen). (bula de Bevacizumabe, Advertências e precauções)

  • Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • …50,000/μL was required for study eligibility ‡ Data were missing at baseline for one patient In the combination study of bortezomib with rituximab, cyclophosphamide, doxorubicin and prednisone (BR-CAP) in previously untreated mantle cell lymphoma patients, the incidence of thrombocytopenia (≥ Grade 4) was 32% vs 1% for the rituximab, cyclophosphamide, doxorubicin,… (bula de Bortezomibe, Advertências e precauções)

  • Bumetanidadiurético de alçaLeve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (bula de Bussulfano, Advertências)

  • Calcitriolanálogo da vitamina DLeve

    Corticosteroids A relationship of functional antagonism exists between vitamin D analogues, which promote calcium absorption, and corticosteroids, which inhibit calcium absorption. (bula de Calcitriol, Interações medicamentosas)

  • Some subjects in the EPIDIOLEX clinical trials had pruritus, erythema, and angioedema requiring treatment, including corticosteroids and antihistamines. (bula de Canabidiol (medicamento de prescrição), Advertências e precauções)

  • Candesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Leve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • CefaclorcefalosporinaLeve

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (bula de Cefaclor, Advertências)

  • CefadroxilacefalosporinaLeve

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (bula de Cefadroxila, Advertências e precauções)

  • CefdinircefalosporinaLeve

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (bula de Cefdinir, Advertências)

  • CefotetanacefalosporinaLeve

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (bula de Cefotetana, Advertências)

  • CefprozilacefalosporinaLeve

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (bula de Cefprozila, Advertências)

  • CeftazidimacefalosporinaLeve

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, IV FLUIDS, IV ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (bula de Ceftazidima, Advertências)

  • CeftriaxonacefalosporinaLeve

    Serious acute hypersensitivity reactions may require treatment with epinephrine and other emergency measures including oxygen, corticosteroids, intravenous fluids, intravenous antihistamines, pressor amines, and airway management, as clinically indicated. (bula de Ceftriaxona, Advertências e precauções)

  • Sixteen (16) drugs tested did not show an in vitro interaction with LOKELMA (allopurinol, apixaban, aspirin, captopril, cyclosporine, digoxin, ethinyl estradiol, lisinopril, magnesium, metformin, phenytoin, prednisone, propranolol, quinapril, spironolactone and ticagrelor). (bula de Ciclossilicato de zircônio sódico, Interações medicamentosas)

  • ClofarabinaantimetabólitoLeve

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (bula de Clofarabina, Advertências e precauções)

  • Clomifenomodulador seletivo do receptor de estrogênioLeve

    Elevated urinary steroid levels, varying degrees of electrolyte imbalance, hypovolemia, hemoconcentration, and hypoproteinemia may occur. (bula de Clomifeno, Advertências)

  • Clorotiazidadiurético tiazídicoLeve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • Clortalidonadiurético tiazídicoLeve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • The recovery of the adrenal gland may take from days to months so patients should be protected from the stress (e.g., trauma or surgery) by the use of corticosteroids during the period of stress. (bula de Corticotropina, Advertências e precauções)

  • Fluid retention events were typically managed by supportive care measures that may include diuretics or short courses of steroids. (bula de Dasatinibe, Advertências e precauções)

  • Dextroanfetaminaestimulante do SNCLeve

    Drug/Laboratory Test Interactions Amphetamines can cause a significant elevation in plasma corticosteroid levels. (bula de Dextroanfetamina, Interações medicamentosas)

  • Donepezilainibidor da colinesteraseLeve

    Anticholinesterase Agents Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (bula de Prednisona, Interações medicamentosas)

  • Droperidolantagonista da dopaminaLeve

    These would include diuretics, laxatives and supraphysiological use of steroid hormones with mineralocorticoid potential. (bula de Droperidol, Interações medicamentosas)

  • Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • Eplerenonaantagonista da aldosteronaLeve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • Espironolactonaantagonista da aldosteronaLeve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • Espironolactona + hidroclorotiazidaantagonista da aldosteronaLeve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • Fenoximetilpenicilina (penicilina V)antibiótico da classe das penicilinasLeve

    OXYGEN, INTRAVENOUS STEROIDS, AND AIRWAY MANAGEMENT, INCLUDING INTUBATION, SHOULD ALSO BE ADMINISTERED AS INDICATED. (bula de Fenoximetilpenicilina (penicilina V), Advertências)

  • Fisostigminainibidor da colinesteraseLeve

    Anticholinesterase Agents Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (bula de Prednisona, Interações medicamentosas)

  • FludarabinaantimetabólitoLeve

    Steroids may or may not be effective in controlling these hemolytic episodes. (bula de Fludarabina, Advertências e precauções)

  • FludrocortisonacorticosteroideLeve

    Since mineralocorticoid secretion may be impaired, salt and/or a mineralocorticoid should be administered concurrently. (bula de Prednisona, Advertências e precauções)

  • FluoxetinaISRSLeve

    Most patients improved promptly with discontinuation of fluoxetine and/or adjunctive treatment with antihistamines or steroids, and all patients experiencing these reactions were reported to recover completely. (bula de Fluoxetina, Advertências e precauções)

  • Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • Furosemidadiurético de alçaLeve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • Galantaminainibidor da colinesteraseLeve

    Anticholinesterase Agents Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (bula de Prednisona, Interações medicamentosas)

  • In the reported cases NME resolved with discontinuation of the glucagon, and treatment with corticosteroids was not effective. (bula de Glucagon, Advertências e precauções)

  • GuselcumabeimunossupressorLeve

    TREMFYA was subsequently discontinued, and the liver test abnormalities resolved following administration of corticosteroids [see Adverse Reactions (6.1) ] . (bula de Guselcumabe, Advertências e precauções)

  • Hidroclorotiazidadiurético tiazídicoLeve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • HidrocortisonacorticosteroideLeve

    Amphotericin B Injection There have been cases reported in which concomitant use of Amphotericin B and hydrocortisone was followed by cardiac enlargement and congestive heart failure [see Drug Interactions (7.14) ] . (bula de Prednisona, Interações medicamentosas)

  • Indapamidadiurético tiazídicoLeve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • IpratrópioanticolinérgicoLeve

    ATROVENT HFA has been used concomitantly with other drugs, including sympathomimetic bronchodilators, methylxanthines, oral and inhaled steroids commonly used in the treatment of COPD. (bula de Ipratrópio, Interações medicamentosas)

  • Irbesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Leve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • Patients with Grade 1 and 2 TFR may also be treated with corticosteroids, non-steroidal anti-inflammatory drugs (NSAIDs) and/or narcotic analgesics for management of TFR symptoms. (bula de Lenalidomida, Advertências e precauções)

  • Losartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Leve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • The infusion should be terminated immediately, followed by the administration of volume expanders, pressor agents, corticosteroids, or antihistamines at the discretion of the physician. (bula de Melfalana, Advertências)

  • Memantina + donepezilainibidor da colinesteraseLeve

    Anticholinesterase Agents Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (bula de Prednisona, Interações medicamentosas)

  • Metanfetaminaestimulante do SNCLeve

    Drug/Laboratory Test Interactions Amphetamines can cause a significant elevation in plasma corticosteroid levels. (bula de Metanfetamina, Interações medicamentosas)

  • Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • Midodrinaagonista alfa-adrenérgicoLeve

    Midodrine hydrochloride has been used in patients concomitantly treated with salt-retaining steroid therapy (i.e., fludrocortisone acetate), with or without salt supplementation. (bula de Midodrina, Interações medicamentosas)

  • Naltrexonaantagonista opioideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • Neostigminainibidor da colinesteraseLeve

    Anticholinesterase Agents Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (bula de Prednisona, Interações medicamentosas)

  • Nimodipinobloqueador dos canais de cálcio di-hidropiridínicoLeve

    Moderate and weak CYP3A4 inducers include, for example: amprenavir, aprepitant, armodafinil, bosentan, efavirnenz, etravirine, Echinacea, modafinil, nafcillin, pioglitazone, prednisone, rufinamide, and vemurafenib. (bula de Nimodipino, Interações medicamentosas)

  • Olanzapina + fluoxetinaantipsicóticoLeve

    Most patients improved promptly with discontinuation of fluoxetine and/or adjunctive treatment with antihistamines or steroids, and all patients experiencing these reactions were reported to recover completely. (bula de Olanzapina + fluoxetina, Advertências e precauções)

  • Olmesartana + anlodipino + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Leve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • Olmesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Leve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • Oxacilinaantibiótico da classe das penicilinasLeve

    If an allergic reaction occurs, the drug should be discontinued and the patient should receive supportive treatment, e.g. , artificial maintenance of ventilation, pressor amines, antihistamines, and corticosteroids. (bula de Oxacilina, Advertências)

  • Pilocarpinaagonista colinérgicoLeve

    …performed, the following concomitant drugs were used in at least 10% of patients in either or both Sjogren's efficacy studies: acetylsalicylic acid, artificial tears, calcium, conjugated estrogens, hydroxychloroquine sulfate, ibuprofen, levothyroxine sodium, medroxyprogesterone acetate, methotrexate, multivitamins, naproxen, omeprazole, paracetamol, and prednisone. (bula de Pilocarpina, Interações medicamentosas)

  • Piridostigminainibidor da colinesteraseLeve

    Anticholinesterase Agents Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (bula de Prednisona, Interações medicamentosas)

  • Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • QuininaantimaláricoLeve

    Drug/Laboratory Interactions Quinine may produce an elevated value for urinary 17-ketogenic steroids when the Zimmerman method is used. (bula de Quinina, Interações medicamentosas)

  • Raloxifenomodulador seletivo do receptor de estrogênioLeve

    Other Concomitant Medications EVISTA can be concomitantly administered with ampicillin, amoxicillin, antacids, corticosteroids, and digoxin [see Clinical Pharmacology ( 12.3 )] . (bula de Raloxifeno, Interações medicamentosas)

  • RituximabeimunossupressorLeve

    Institute medical management (e.g., glucocorticoids, epinephrine, bronchodilators, or oxygen) for infusion-related reactions as needed. (bula de Rituximabe, Advertências e precauções)

  • Rivastigminainibidor da colinesteraseLeve

    Anticholinesterase Agents Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (bula de Prednisona, Interações medicamentosas)

  • Telmisartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Leve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • If symptoms of hypersensitivity occur, initiate appropriate therapy (e.g., antihistamines, corticosteroids, epinephrine). (bula de Tenecteplase, Advertências e precauções)

  • TobramicinaaminoglicosídeoLeve

    In clinical studies, patients receiving TOBI Podhaler continued to take dornase alfa, bronchodilators, inhaled corticosteroids, and macrolides. (bula de Tobramicina, Interações medicamentosas)

  • Trianterenodiurético poupador de potássioLeve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • UstequinumabeimunossupressorLeve

    Patients improved with discontinuation of therapy and in certain cases administration of corticosteroids. (bula de Ustequinumabe, Advertências e precauções)

  • Valsartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Leve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (bula de Prednisona, Interações medicamentosas)

  • Vitamina DVitaminas e mineraisLeve

    Corticosteroides como a prednisona reduzem a absorção de cálcio e prejudicam o metabolismo da vitamina D, contribuindo para a perda óssea. (NIH Office of Dietary Supplements, Vitamin D)

  • ZiprasidonaantipsicóticoLeve

    Most patients improved promptly with adjunctive treatment with antihistamines or steroids and/or upon discontinuation of ziprasidone, and all patients experiencing these reactions were reported to recover completely. (bula de Ziprasidona, Advertências e precauções)

Nenhuma interação significativa relatada (2)

  • AminofilinametilxantinaSem interação

    …influenza vaccine ketoconazole lomefloxacin mebendazole medroxyprogesterone methylprednisolone metronidazole metoprolol nadolol nifedipine nizatidine norfloxacin ofloxacin omeprazole prednisone, prednisolone ranitidine rifabutin roxithromycin sorbitol (purgative doses do not inhibit theophylline absorption) sucralfate terbutaline, systemic terfenadine tetracycline… (bula de Aminofilina, Interações medicamentosas)

  • Zileutonainibidor da CYP1A2Sem interação

    Other Concomitant Drug Therapy Drug-drug interaction studies conducted in healthy subjects between zileuton immediate-release tablets and prednisone and ethinyl estradiol (oral contraceptive), drugs known to be metabolized by the CYP3A4 isoenzyme, have shown no significant interaction. (bula de Zileutona, Interações medicamentosas)

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