Parasetamol etkileşimleri
Parasetamol (Tylenol, Ofirmev, Panadol) için dizinlediğimiz FDA etiketlerinde ve bilgi sayfalarında 63 belgelenmiş etkileşim var: 3 majör, 45 orta, 8 minör ve bir etiketin anlamlı etkileşim olmadığını bildirdiği 7 çift. Aşağıdaki her kayıt, dayandığı cümleyi alıntılar. Bu ilaç sayfası bir başlangıç noktasıdır; sizin durumunuz için verilmiş bir hüküm değildir.
Parasetamol nasıl görünür
11 sürümün tümüÇizimler, FDA etiketlerindeki ürün bilgilerinden oluşturulmuştur: renk, şekil, boyut ve baskı. 12 firmaya ait 11 belgelenmiş sürüm.
Parasetamol hakkında
Gerçekler, mitler ve internetteki iddialarParasetamol (Amerika Birleşik Devletleri'nde asetaminofen olarak adlandırılır), Tylenol, Panadol, Mapap ve pek çok jenerik ürün olarak reçetesiz satılan, ayrıca opioidlerle kombinasyon hâlinde ve Ofirmev adlı enjeksiyon olarak reçeteyle verilen bir ağrı kesici ve ateş düşürücüdür. Baş ağrısı, diş ağrısı, sırt ağrısı, soğuk algınlığı ve artritten kaynaklanan hafif ila orta şiddetteki ağrıyı giderir ve ateşi düşürür. Reçetesiz tabletler genellikle 4 ila 6 saatte bir alınır ve etikette günlük bir üst sınır yer alır. İbuprofenden farklı olarak iltihabı azaltmaz.
Etikete göre etkileşimler
Majör etkileşimler (3)
- AsetilsisteinMajör
Hypersensitivity Reactions Serious acute hypersensitivity reactions; including fatal or life-threatening anaphylaxis, rash, hypotension, wheezing, and/or shortness of breath; have been observed in patients receiving intravenous acetylcysteine for acetaminophen overdose and occurred soon after initiation of the infusion [ see Adverse Reactions ( 6 ) ]. (Asetilsistein etiketi, Uyarılar ve önlemler)
- MetiraponMajör
Acetaminophen: Avoid concomitant use with Metopirone. (Metirapon etiketi, İlaç etkileşimleri)
A baby nursing from an ultra-rapid metabolizer mother taking tramadol hydrochloride and acetaminophen could potentially be exposed to high levels of M1, and experience life-threatening respiratory depression. (Tramadol ve parasetamol etiketi, Uyarılar ve önlemler)
Orta düzey etkileşimler (45)
Premedicate patients with an antihistamine and acetaminophen prior to each dose. (Alemtuzumab etiketi, Uyarılar ve önlemler)
Düzenli veya yoğun alkol tüketimi, parasetamole bağlı karaciğer hasarı riskini artırır. (NIAAA, Harmful Interactions: Mixing Alcohol with Medicines)
Chronic oral acetaminophen use at a dose of 4,000 mg/day has been shown to cause an increase in international normalized ratio (INR) in some patients who have been stabilized on sodium warfarin as an anticoagulant. (Parasetamol etiketi, İlaç etkileşimleri)
Chronic oral acetaminophen use at a dose of 4,000 mg/day has been shown to cause an increase in international normalized ratio (INR) in some patients who have been stabilized on sodium warfarin as an anticoagulant. (Parasetamol etiketi, İlaç etkileşimleri)
…Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine Monoamine Oxidase Inhibitors, Nonselective Beta-Adrenergic Antagonists, or Tricyclic Antidepressants: May produce severe, prolonged… (Artikain ve adrenalin etiketi, İlaç etkileşimleri)
Chronic oral acetaminophen use at a dose of 4,000 mg/day has been shown to cause an increase in international normalized ratio (INR) in some patients who have been stabilized on sodium warfarin as an anticoagulant. (Parasetamol etiketi, İlaç etkileşimleri)
…Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine 7.6 Potent Inhalation Anesthetics Serious dose-related cardiac arrhythmias may occur if preparations containing a vasoconstrictor… (Bupivakain ve adrenalin etiketi, İlaç etkileşimleri)
Effects of Other Substances on Acetaminophen Substances that induce or regulate hepatic cytochrome enzyme CYP2E1 may alter the metabolism of acetaminophen and increase its hepatotoxic potential. (Parasetamol etiketi, İlaç etkileşimleri)
Effects of Other Substances on Acetaminophen Substances that induce or regulate hepatic cytochrome enzyme CYP2E1 may alter the metabolism of acetaminophen and increase its hepatotoxic potential. (Parasetamol etiketi, İlaç etkileşimleri)
Effects of Other Substances on Acetaminophen Substances that induce or regulate hepatic cytochrome enzyme CYP2E1 may alter the metabolism of acetaminophen and increase its hepatotoxic potential. (Parasetamol etiketi, İlaç etkileşimleri)
Chronic oral acetaminophen use at a dose of 4,000 mg/day has been shown to cause an increase in international normalized ratio (INR) in some patients who have been stabilized on sodium warfarin as an anticoagulant. (Parasetamol etiketi, İlaç etkileşimleri)
Ascorbic acid and acetaminophen may increase plasma EE concentrations, possibly by inhibition of conjugation. (Desogestrel ve etinilestradiol etiketi, İlaç etkileşimleri)
Acetaminophen In normal volunteers, concomitant administration of diflunisal and acetaminophen resulted in an approximate 50% increase in plasma levels of acetaminophen. (Diflunisal etiketi, İlaç etkileşimleri)
Exercise caution when prescribing ZIPSOR with concomitant drugs that are known to be potentially hepatotoxic (e.g., acetaminophen, antibiotics, antiepileptics). (Diklofenak etiketi, Uyarılar ve önlemler)
Ascorbic acid and acetaminophen may increase plasma EE concentrations, possibly by inhibition of conjugation. (Drospirenon ve etinilestradiol etiketi, İlaç etkileşimleri)
Chronic oral acetaminophen use at a dose of 4,000 mg/day has been shown to cause an increase in international normalized ratio (INR) in some patients who have been stabilized on sodium warfarin as an anticoagulant. (Parasetamol etiketi, İlaç etkileşimleri)
Chronic oral acetaminophen use at a dose of 4,000 mg/day has been shown to cause an increase in international normalized ratio (INR) in some patients who have been stabilized on sodium warfarin as an anticoagulant. (Parasetamol etiketi, İlaç etkileşimleri)
Ascorbic acid and acetaminophen may increase plasma ethinyl estradiol concentrations, possibly by inhibition of conjugation. (Etonogestrel ve etinilestradiol etiketi, İlaç etkileşimleri)
Chronic oral acetaminophen use at a dose of 4,000 mg/day has been shown to cause an increase in international normalized ratio (INR) in some patients who have been stabilized on sodium warfarin as an anticoagulant. (Parasetamol etiketi, İlaç etkileşimleri)
Chronic oral acetaminophen use at a dose of 4,000 mg/day has been shown to cause an increase in international normalized ratio (INR) in some patients who have been stabilized on sodium warfarin as an anticoagulant. (Parasetamol etiketi, İlaç etkileşimleri)
Effects of Other Substances on Acetaminophen Substances that induce or regulate hepatic cytochrome enzyme CYP2E1 may alter the metabolism of acetaminophen and increase its hepatotoxic potential. (Parasetamol etiketi, İlaç etkileşimleri)
Medications for the treatment of hypersensitivity reactions (e.g., acetaminophen, antihistamines, corticosteroids and/or epinephrine) should be available for immediate use in the event of a reaction [see Dosage and Administration (2.10) and Adverse Reactions (6.1) ] . (İnfliksimab etiketi, Uyarılar ve önlemler)
Acetaminophen A report of severe acetaminophen toxicity was reported in a patient receiving isoniazid. (İzoniazid etiketi, İlaç etkileşimleri)
…procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants Phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine (Kloroprokain etiketi, Önlemler)
Ascorbic acid and acetaminophen may increase systemic exposure of ethinyl estradiol, possibly by inhibition of conjugation. (Levonorgestrel ve etinilestradiol etiketi, İlaç etkileşimleri)
…Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine 7.6 Potent Inhalation Anesthetics Serious dose-related cardiac arrhythmias may occur if preparations containing epinephrine are… (Lidokain ve adrenalin etiketi, İlaç etkileşimleri)
…prilocaine, procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea, isofamide, rasburicase Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sufonamides Antimalarials chloroquine, primaquine Anticonvulsants Phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine (Lidokain ve prilokain etiketi, İlaç etkileşimleri)
- LomitapidOrta
Caution should be exercised when JUXTAPID is used with other medications known to have potential for hepatotoxicity, such as isotretinoin, amiodarone, acetaminophen (>4 g/day for ≥3 days/week), methotrexate, tetracyclines, and tamoxifen. (Lomitapid etiketi, Uyarılar ve önlemler)
…procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine (Mepivakain etiketi, İlaç etkileşimleri)
- MotiksafortidOrta
Premedicate with an analgesic medication (e.g., acetaminophen) prior to each APHEXDA dose. (Motiksafortid etiketi, Uyarılar ve önlemler)
Ascorbic acid and acetaminophen may increase plasma EE concentrations, possibly by inhibition of conjugation. (Norelgestromin ve etinilestradiol etiketi, İlaç etkileşimleri)
Ascorbic acid and acetaminophen may increase plasma ethinyl estradiol levels, possibly by inhibition of conjugation. (Noretisteron ve etinilestradiol etiketi, İlaç etkileşimleri)
Ascorbic acid and acetaminophen may increase plasma EE concentrations, possibly by inhibition of conjugation. (Norgestimat ve etinilestradiol etiketi, İlaç etkileşimleri)
Ascorbic acid and acetaminophen may increase plasma EE concentrations, possibly by inhibition of conjugation. (Norgestrel ve etinilestradiol etiketi, İlaç etkileşimleri)
The addition of an antipyretic (e.g., acetaminophen) may also be considered [see Dosage and Administration (2.2) ]. (Okrelizumab etiketi, Uyarılar ve önlemler)
Effects of Other Substances on Acetaminophen Substances that induce or regulate hepatic cytochrome enzyme CYP2E1 may alter the metabolism of acetaminophen and increase its hepatotoxic potential. (Parasetamol etiketi, İlaç etkileşimleri)
Effects of Other Substances on Acetaminophen Substances that induce or regulate hepatic cytochrome enzyme CYP2E1 may alter the metabolism of acetaminophen and increase its hepatotoxic potential. (Parasetamol etiketi, İlaç etkileşimleri)
Effects of Other Substances on Acetaminophen Substances that induce or regulate hepatic cytochrome enzyme CYP2E1 may alter the metabolism of acetaminophen and increase its hepatotoxic potential. (Parasetamol etiketi, İlaç etkileşimleri)
…Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine The administration of local anesthetic injections containing epinephrine or norepinephrine to patients receiving monoamine oxidase… (Prilokain ve adrenalin etiketi, İlaç etkileşimleri)
- ProbenesidOrta
In patients on probenecid who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (Probenesid etiketi, Uyarılar)
In patients on probenecid and colchicine who require a mild analgesic agent the use of acetaminophen rather than small doses of salicylates would be preferred. (Probenesid ve kolşisin etiketi, Uyarılar)
Chronic oral acetaminophen use at a dose of 4,000 mg/day has been shown to cause an increase in international normalized ratio (INR) in some patients who have been stabilized on sodium warfarin as an anticoagulant. (Parasetamol etiketi, İlaç etkileşimleri)
…Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants Phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine NAROPIN should be used with caution in patients receiving other local anesthetics or agents structurally related to amide- type… (Ropivakain etiketi, İlaç etkileşimleri)
Chronic oral acetaminophen use at a dose of 4,000 mg/day has been shown to cause an increase in international normalized ratio (INR) in some patients who have been stabilized on sodium warfarin as an anticoagulant. (Parasetamol etiketi, İlaç etkileşimleri)
- ZenokutuzumabOrta
Prior to the first BIZENGRI infusion, premedicate with a corticosteroid, an H1 antihistamine and acetaminophen to reduce the risk of IRRs [see Dosage and Administration (2.4) ]. (Zenokutuzumab etiketi, Uyarılar ve önlemler)
Minör değinmeler (8)
Drug Interactions There was no evidence of drug interactions in clinical studies in which dobutamine was administered concurrently with other drugs, including digitalis preparations, furosemide, spironolactone, lidocaine, glyceryl trinitrate, isosorbide dinitrate, morphine, atropine, heparin, protamine, potassium chloride, folic acid, and acetaminophen. (Dobutamin etiketi, İlaç etkileşimleri)
Orally Administered Drugs (e.g., acetaminophen) Clinical Impact Exenatide slows gastric emptying. (Eksenatid etiketi, İlaç etkileşimleri)
Other Concomitant Therapy Although specific interaction studies were not performed, PROSCAR was concomitantly used in clinical studies with acetaminophen, acetylsalicylic acid, α-blockers, angiotensin-converting enzyme (ACE) inhibitors, analgesics, anti-convulsants, beta-adrenergic blocking agents, diuretics, calcium channel blockers, cardiac nitrates, HMG-CoA… (Finasterid etiketi, İlaç etkileşimleri)
Drugs metabolized by CYP3A4 or CYP1A2 include the following: Acetaminophen, albendazole, alprazolam, aprepitant, buprenorphone, bupropion, buspirone, citalopram, clobazam, clonazepam, clozapine, cyclosporin, delavirdine, desipramine, diazepam, dicumarol, dihydropyridine calcium channel blockers (e.g., felodipine), doxycycline, ethosuximide, everolimus, felbamate,… (Karbamazepin etiketi, İlaç etkileşimleri)
Premedicate patients with an antihistamine and acetaminophen prior to dosing. (Rituksimab etiketi, Uyarılar ve önlemler)
Drug Interactions Probenecid Probenecid is known to interact with the metabolism or renal tubular excretion of many drugs (e.g., acetaminophen, acyclovir, angiotensin-converting enzyme inhibitors, aminosalicylic acid, barbiturates, benzodiazepines, bumetanide, clofibrate, methotrexate, famotidine, furosemide, nonsteroidal anti-inflammatory agents, theophylline,… (Sidofovir etiketi, İlaç etkileşimleri)
Other Drugs: Co-administration of telmisartan did not result in a clinically significant interaction with acetaminophen, amlodipine, glyburide, simvastatin, hydrochlorothiazide, warfarin, or ibuprofen. (Telmisartan ve amlodipin etiketi, İlaç etkileşimleri)
Effect of Other Drugs on Treprostinil Drug interaction studies have been carried out with treprostinil (oral or subcutaneous) co-administered with acetaminophen (4 g/day), warfarin (25 mg/day), and fluconazole (200 mg/day), respectively, in healthy volunteers. (Treprostinil etiketi, İlaç etkileşimleri)
Anlamlı etkileşim olmadığı bildirilenler (7)
No clinically significant drug interactions have been observed between RPV and the following medications: acetaminophen, atorvastatin, chlorzoxazone, ethinyl estradiol, ledipasvir/sofosbuvir, norethindrone, sildenafil, simeprevir, sofosbuvir, sofosbuvir/velpatasvir, sofosbuvir/velpatasvir/voxilaprevir, or TDF. (Emtrisitabin, rilpivirin ve tenofovir etiketi, İlaç etkileşimleri)
Therapeutic concentrations of digoxin, warfarin, ibuprofen, naproxen, piroxicam, acetaminophen, phenytoin and tolbutamide did not alter ketorolac tromethamine protein binding. (Ketorolak etiketi, İlaç etkileşimleri)
…Clinically Significant Drug Interaction with TAMIFLU No dose adjustments are needed for either oseltamivir or the concomitant drug when coadministering oseltamivir with amoxicillin, acetaminophen, aspirin, cimetidine, antacids (magnesium and aluminum hydroxides and calcium carbonates), rimantadine, amantadine, or warfarin [see Clinical Pharmacology (12.3) ] . (Oseltamivir etiketi, İlaç etkileşimleri)
…included in Table 6, the interaction between EDURANT and the following drugs was evaluated in clinical studies and no dose adjustment is needed for either drug [see Clinical Pharmacology (12.3) ] : acetaminophen, atorvastatin, chlorzoxazone, cabotegravir, ethinylestradiol, norethindrone, raltegravir, sildenafil, simeprevir and tenofovir disoproxil fumarate. (Rilpivirin etiketi, İlaç etkileşimleri)
Acetaminophen Acetaminophen had no effect on the plasma levels of sulindac or its sulfide metabolite. (Sulindak etiketi, İlaç etkileşimleri)
Drugs for which either no interaction or a likely clinically unimportant interaction has been observed Acetaminophen Valproate had no effect on any of the pharmacokinetic parameters of acetaminophen when it was concurrently administered to three epileptic patients. (Valproik asit etiketi, İlaç etkileşimleri)
Kullandığınız her şeyi Parasetamol ile karşılaştırın. Tüm listenizi ekleyin; her çift tek seferde kontrol edilir.
Sorgulama aracında açTıbbi tavsiye değildir. Şiddet derecesi sizin koşullarınızı değil, etiketin ifadesini yansıtır. “Majör” işareti gözetim altında olağan bir uygulama olabilir, “minör” işareti ise yüksek dozlarda önem kazanabilir. Bir eczacıya danışın.



