Selejilin etkileşimleri

MAO inhibitörü sınıfından Selejilin (Emsam, Zelapar, Eldepryl) için dizinlediğimiz FDA etiketlerinde ve bilgi sayfalarında 255 belgelenmiş etkileşim var: 127 majör, 120 orta, 8 minör ve bir etiketin anlamlı etkileşim olmadığını bildirdiği 0 çift. Aşağıdaki her kayıt, dayandığı cümleyi alıntılar. Bu ilaç sayfası bir başlangıç noktasıdır; sizin durumunuz için verilmiş bir hüküm değildir.

Etikete göre etkileşimler

Majör etkileşimler (127)

  • AmfetaminMSS uyarıcısıMajör

    Patients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive crisis [ see Warnings and Precautions (5.7) , Drug Interactions (7.1) ]. (Amfetamin etiketi, Kontrendikasyonlar)

  • Amfetamin ve dekstroamfetaminMSS uyarıcısıMajör

    Hypersensitivity reactions such as angioedema and anaphylactic reactions have been reported in patients treated with other amphetamine products [see Adverse Reactions ( 6.2 )] . taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive… (Amfetamin ve dekstroamfetamin etiketi, Kontrendikasyonlar)

  • Amitriptilintrisiklik antidepresanMajör

    John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (Selejilin etiketi, Kontrendikasyonlar)

  • Amoksapintrisiklik antidepresanMajör

    John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (Selejilin etiketi, Kontrendikasyonlar)

  • Apraklonidinalfa adrenerjik agonistMajör

    CONTRAINDICATIONS IOPIDINE 1% Ophthalmic Solution is contraindicated for patients receiving monoamine oxidase inhibitor therapy and for patients with hypersensitivity to any component of this medication or to clonidine. (Apraklonidin etiketi, Kontrendikasyonlar)

  • Atomoksetinnoradrenalin geri alım inhibitörüMajör

    Taking, or within 14 days of stopping, a monoamine oxidase inhibitor (MAOI) [see Drug Interactions (7) ] . (Atomoksetin etiketi, Kontrendikasyonlar)

  • Baklofenkas gevşeticiMajör

    John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (Selejilin etiketi, Kontrendikasyonlar)

  • ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • BenzfetaminMSS uyarıcısıMajör

    Hypertensive crises have resulted when sympathomimetic amines have been used concomitantly or within 14 days following use of monoamine oxidase inhibitors. (Benzfetamin etiketi, Kontrendikasyonlar)

  • • Concomitant use of dextromethorphan, because of reported episodes of psychosis or bizarre behavior. (Selejilin etiketi, Kontrendikasyonlar)

  • BuprenorfinopioidMajör

    ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • BupropionantidepresanMajör

    • May cause serotonin syndrome when used with antidepressants (5.2) (Selejilin etiketi, Uyarılar ve önlemler)

  • Buspironserotonerjik ilaçMajör

    The use of monoamine oxidase inhibitors (MAOIs) intended to treat depression with buspirone or within 14 days of stopping treatment with buspirone is contraindicated because of an increased risk of serotonin syndrome and/or elevated blood pressure. (Buspiron etiketi, Kontrendikasyonlar)

  • ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • ButorfanolopioidMajör

    ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • Dantrolenkas gevşeticiMajör

    John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (Selejilin etiketi, Kontrendikasyonlar)

  • DeksklorfeniraminantihistaminikMajör

    Antihistamines are also contraindicated in the following conditions: Hypersensitivity to dexchlorpheniramine maleate or other antihistamines of similar chemical structure Monoamine oxidase inhibitor therapy (See Drug Interaction section) (Deksklorfeniramin etiketi, Kontrendikasyonlar)

  • DeksmetilfenidatMSS uyarıcısıMajör

    • Concomitant treatment with monoamine oxidase inhibitors (MAOIs) or within 14 days following discontinuation of treatment with an MAOI, because of the risk of hypertensive crises [see Drug Interactions ( 7.1 )] . (Deksmetilfenidat etiketi, Kontrendikasyonlar)

  • DekstroamfetaminMSS uyarıcısıMajör

    Patients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive crisis [see Warnings and Drug Interactions ]. (Dekstroamfetamin etiketi, Kontrendikasyonlar)

  • Dekstrometorfanserotonerjik ilaçMajör

    • Concomitant use of dextromethorphan, because of reported episodes of psychosis or bizarre behavior. (Selejilin etiketi, Kontrendikasyonlar)

  • Dekstrometorfan ve kinidinserotonerjik ilaçMajör

    • Concomitant use of dextromethorphan, because of reported episodes of psychosis or bizarre behavior. (Selejilin etiketi, Kontrendikasyonlar)

  • Desipramintrisiklik antidepresanMajör

    John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (Selejilin etiketi, Kontrendikasyonlar)

  • DesvenlafaksinSNRIMajör

    • May cause serotonin syndrome when used with antidepressants (5.2) (Selejilin etiketi, Uyarılar ve önlemler)

  • DietilpropionMSS uyarıcısıMajör

    During or within 14 days following the administration of monoamine oxidase inhibitors, hypertensive crises may result. (Dietilpropion etiketi, Kontrendikasyonlar)

  • Avoid use of diphenoxylate hydrochloride and atropine sulfate in patients who take MAOIs and monitor for signs and symptoms of hypertensive crisis (headache, hyperthermia, hypertension). (Difenoksilat ve atropin etiketi, İlaç etkileşimleri)

  • Doksepintrisiklik antidepresanMajör

    John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (Selejilin etiketi, Kontrendikasyonlar)

  • Doksilamin ve piridoksinantihistaminikMajör

    …Known hypersensitivity to doxylamine succinate, other ethanolamine derivative antihistamines, pyridoxine hydrochloride or any inactive ingredient in the formulation Monoamine oxidase (MAO) inhibitors intensify and prolong the adverse central nervous system effects of doxylamine succinate and pyridoxine hydrochloride delayed-release tablets [ see Drug Interactions… (Doksilamin ve piridoksin etiketi, Kontrendikasyonlar)

  • DötetrabenazinVMAT2 inhibitörüMajör

    Taking monoamine oxidase inhibitors (MAOIs). (Dötetrabenazin etiketi, Kontrendikasyonlar)

  • DroksidopasempatomimetikMajör

    However, based on mechanism of action, the use of non-selective MAO inhibitors and linezolid should be avoided as there is a potential for increased blood pressure when taken with NORTHERA. (Droksidopa etiketi, İlaç etkileşimleri)

  • DuloksetinSNRIMajör

    • May cause serotonin syndrome when used with antidepressants (5.2) (Selejilin etiketi, Uyarılar ve önlemler)

  • EletriptantriptanMajör

    Selective Serotonin Reuptake Inhibitors/Serotonin and Norepinephrine Reuptake Inhibitors and Serotonin Syndrome Cases of serotonin syndrome have been reported during co-administration of triptans and SSRIs, SNRIs, TCAs and MAO inhibitors [see Warnings and Precautions (5.7) ]. (Eletriptan etiketi, İlaç etkileşimleri)

  • EluksadolinopioidMajör

    ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • EssitalopramSSRIMajör

    • May cause serotonin syndrome when used with antidepressants (5.2) (Selejilin etiketi, Uyarılar ve önlemler)

  • FendimetrazinMSS uyarıcısıMajör

    …coronary artery disease, stroke, arrhythmias, congestive heart failure, uncontrolled hypertension, pulmonary hypertension) • During or within 14 days following the administration of monoamine oxidase inhibitors • Hyperthyroidism • Glaucoma • Agitated states • History of drug abuse • Pregnancy (see PRECAUTIONS, Pregnancy ) • Nursing • Use in combination with other… (Fendimetrazin etiketi, Kontrendikasyonlar)

  • FenelzinMAO inhibitörüMajör

    • Concomitant use of other drugs in the monoamine oxidase inhibitor (MAOI) class or other drugs that are potent inhibitors of monoamine oxidase, including linezolid), because of an increased risk for hypertensive crisis [see Warnings and Precautions (5.1)]. (Selejilin etiketi, Kontrendikasyonlar)

  • FentanilopioidMajör

    ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • FenterminMSS uyarıcısıMajör

    …cardiovascular disease (e.g., coronary artery disease, stroke, arrhythmias, congestive heart failure, uncontrolled hypertension) • During or within 14 days following the administration of monoamine oxidase inhibitors • Hyperthyroidism • Glaucoma • Agitated states • History of drug abuse • Pregnancy [ see Use in Specific Populations () ] • Nursing [ see Use in Specific… (Fentermin etiketi, Kontrendikasyonlar)

  • Fentermin ve topiramatMSS uyarıcısıMajör

    …Warnings and Precautions (5.1) and Use in Specific Populations (8.1) ] With glaucoma [see Warnings and Precautions (5.3) ] With hyperthyroidism Taking or within 14 days of stopping a monoamine oxidase inhibitors [see Drug Interactions (7) ] With known hypersensitivity to phentermine, topiramate or any of the excipients in phentermine and topiramate extended-release… (Fentermin ve topiramat etiketi, Kontrendikasyonlar)

  • FluoksetinSSRIMajör

    • May cause serotonin syndrome when used with antidepressants (5.2) (Selejilin etiketi, Uyarılar ve önlemler)

  • FluvoksaminSSRIMajör

    • May cause serotonin syndrome when used with antidepressants (5.2) (Selejilin etiketi, Uyarılar ve önlemler)

  • FrovatriptantriptanMajör

    Selective Serotonin Reuptake Inhibitors / Serotonin Norepinephrine Reuptake Inhibitors and Serotonin Syndrome Cases of serotonin syndrome have been reported during combined use of triptans and SSRIs, SNRIs, TCAs, and MAO inhibitors [ see Warnings and Precautions (5.7) ]. (Frovatriptan etiketi, İlaç etkileşimleri)

  • GranisetronQT aralığını uzatan ilaçMajör

    Patients should be monitored for the emergence of serotonin syndrome, especially with concomitant use of granisetron and other serotonergic drugs. (Granisetron etiketi, Uyarılar ve önlemler)

  • HidrokodonopioidMajör

    ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • HidromorfonopioidMajör

    ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • İmipramintrisiklik antidepresanMajör

    John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (Selejilin etiketi, Kontrendikasyonlar)

  • İzoniazidantibiyotikMajör

    • Concomitant use of other drugs in the monoamine oxidase inhibitor (MAOI) class or other drugs that are potent inhibitors of monoamine oxidase, including linezolid), because of an increased risk for hypertensive crisis [see Warnings and Precautions (5.1)]. (Selejilin etiketi, Kontrendikasyonlar)

  • KarbamazepinantikonvülsanMajör

    Concomitant use of monoamine oxidase inhibitors (MAOIs). (Karbamazepin etiketi, Kontrendikasyonlar)

  • KarbidopaMajör

    Nonselective monoamine oxidase (MAO) inhibitors are contraindicated for use with levodopa or carbidopa-levodopa combination products with or without carbidopa. (Karbidopa etiketi, Kontrendikasyonlar)

  • Karbidopa ve levodopadopaminerjik ilaçMajör

    DUOPA is contraindicated in patients who are currently taking a nonselective monoamine oxidase (MAO) inhibitor (e.g., phenelzine and tranylcypromine) or have recently (within 2 weeks) taken a nonselective MAO inhibitor. (Karbidopa ve levodopa etiketi, Kontrendikasyonlar)

  • Karbidopa, levodopa ve entakapondopaminerjik ilaçMajör

    Carbidopa, levodopa and entacapone tablets is contraindicated in patients: Taking nonselective monoamine oxidase (MAO) inhibitors (e.g., phenelzine and tranylcypromine). (Karbidopa, levodopa ve entakapon etiketi, Kontrendikasyonlar)

  • KarbinoksaminantihistaminikMajör

    …because deaths have been reported in this age group [see Warnings and Precautions (5.1)]. patients who are hypersensitive to carbinoxamine maleate or any of the inactive ingredients in Carbinoxamine Maleate Extended-Release Oral Suspension [see Warnings and Precautions (5.4)]. patients who are taking monoamine oxidase inhibitors (MAOI) [see Drug Interactions (7)]. (Karbinoksamin etiketi, Kontrendikasyonlar)

  • Karisoprodolkas gevşeticiMajör

    John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (Selejilin etiketi, Kontrendikasyonlar)

  • Klomipramintrisiklik antidepresanMajör

    John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (Selejilin etiketi, Kontrendikasyonlar)

  • Klorzoksazonkas gevşeticiMajör

    John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (Selejilin etiketi, Kontrendikasyonlar)

  • KodeinopioidMajör

    ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • Levodopadopaminerjik ilaçMajör

    INBRIJA is contraindicated in patients currently taking a nonselective monoamine oxidase (MAO) inhibitor (e.g., phenelzine and tranylcypromine) or who have recently (within 2 weeks) taken a nonselective MAO inhibitor. (Levodopa etiketi, Kontrendikasyonlar)

  • LevomilnasipranSNRIMajör

    • May cause serotonin syndrome when used with antidepressants (5.2) (Selejilin etiketi, Uyarılar ve önlemler)

  • LevorfanolopioidMajör

    ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • LinezolidantibiyotikMajör

    MAO Inhibitors ZELAPAR is contraindicated for concomitant use with other drugs in the MAOI class or other drugs that are potent inhibitors of monoamine oxidase (including linezolid, an oxazolidinone antibacterial, which also has reversible nonselective MAO inhibition activity) because of the increased risk for hypertensive crisis [see Contraindications (4) and… (Selejilin etiketi, İlaç etkileşimleri)

  • LisdeksamfetaminMSS uyarıcısıMajör

    Patients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive crisis [see Warnings and Precautions (5.7) and Drug Interactions (7.1) ] . (Lisdeksamfetamin etiketi, Kontrendikasyonlar)

  • Lityumserotonerjik ilaçMajör

    If concomitant use of lithium with other serotonergic drugs is clinically warranted, inform patients of the increased risk for serotonin syndrome and monitor for symptoms. (Lityum etiketi, Uyarılar ve önlemler)

  • MetadonopioidMajör

    ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • Metaksalonkas gevşeticiMajör

    John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (Selejilin etiketi, Kontrendikasyonlar)

  • MetamfetaminMSS uyarıcısıMajör

    Hypersensitivity reactions such as angioedema and anaphylactic reactions have been reported in patients treated with other amphetamine products [see Adverse Reactions ( 6 )]. taking monoamine oxidase inhibitors (MAOIs), or within 14 days following discontinuation of treatment with an MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because… (Metamfetamin etiketi, Kontrendikasyonlar)

  • MetildopaantihipertansifMajör

    CONTRAINDICATIONS Methyldopa is contraindicated in patients: – with active hepatic disease, such as acute hepatitis and active cirrhosis. – with liver disorders previously associated with methyldopa therapy (see WARNINGS ). – with hypersensitivity to any component of this product. – on therapy with monoamine oxidase (MAO) inhibitors. (Metildopa etiketi, Kontrendikasyonlar)

  • Metilen mavisiMAO inhibitörüMajör

    • Concomitant use of other drugs in the monoamine oxidase inhibitor (MAOI) class or other drugs that are potent inhibitors of monoamine oxidase, including linezolid), because of an increased risk for hypertensive crisis [see Warnings and Precautions (5.1)]. (Selejilin etiketi, Kontrendikasyonlar)

  • MetilfenidatMSS uyarıcısıMajör

    Concomitant treatment with monoamine oxidase inhibitors (MAOIs), and also within a minimum of 14 days following discontinuation of treatment with a monoamine oxidase inhibitor because of the risk of hypertensive crisis [see Drug Interactions (7.1) ]. (Metilfenidat etiketi, Kontrendikasyonlar)

  • Metokarbamolkas gevşeticiMajör

    John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (Selejilin etiketi, Kontrendikasyonlar)

  • Metoklopramiddopamin antagonistiMajör

    In one study in hypertensive patients, intravenously administered metoclopramide was shown to release catecholamines; hence, avoid use in patients with hypertension or in patients taking monoamine oxidase inhibitors [see Drug Interactions ( 7.1 )] . (Metoklopramid etiketi, Uyarılar ve önlemler)

  • Midodrinalfa adrenerjik agonistMajör

    Avoid use of MAO inhibitors or linezolid with midodrine. (Midodrin etiketi, İlaç etkileşimleri)

  • MilnasipranSNRIMajör

    • Serotonin Syndrome and MAOIs: Do not use MAOIs intended to treat psychiatric disorders with milnacipran hydrochloride or within 5 days of stopping treatment with milnacipran hydrochloride. (Milnasipran etiketi, Kontrendikasyonlar)

  • MirtazapinantidepresanMajör

    • May cause serotonin syndrome when used with antidepressants (5.2) (Selejilin etiketi, Uyarılar ve önlemler)

  • MorfinopioidMajör

    ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • NalbufinopioidMajör

    ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • Naltrekson ve bupropionopioid antagonistiMajör

    • May cause serotonin syndrome when used with antidepressants (5.2) (Selejilin etiketi, Uyarılar ve önlemler)

  • NaratriptantriptanMajör

    Selective Serotonin Reuptake Inhibitors/Serotonin Norepinephrine Reuptake Inhibitors and Serotonin Syndrome Cases of serotonin syndrome have been reported during co-administration of triptans and SSRIs, SNRIs, TCAs, and MAO inhibitors [see Warnings and Precautions (5.7)] . (Naratriptan etiketi, İlaç etkileşimleri)

  • NefazodonantidepresanMajör

    • May cause serotonin syndrome when used with antidepressants (5.2) (Selejilin etiketi, Uyarılar ve önlemler)

  • Nortriptilintrisiklik antidepresanMajör

    John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (Selejilin etiketi, Kontrendikasyonlar)

  • OksikodonopioidMajör

    ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • OksimorfonopioidMajör

    ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • OlanzapinantipsikotikMajör

    …serotonin reuptake inhibitors-SSRIs, serotonin-norepinephrine reuptake inhibitors-SNRIs, tricyclic antidepressants, tetracyclic antidepressants, triazolopyridine antidepressants) and a non-selective MAOI (e.g., phenelzine, tranylcypromine) or selective MAO-B inhibitors, such as selegiline (ELDEPRYL), rasagiline (AZILECT), and olanzapine (Zydis) selegiline (ZELAPAR). (Selejilin etiketi, Uyarılar ve önlemler)

  • Olanzapin ve fluoksetinantipsikotikMajör

    • May cause serotonin syndrome when used with antidepressants (5.2) (Selejilin etiketi, Uyarılar ve önlemler)

  • OliseridinopioidMajör

    ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • OndansetronQT aralığını uzatan ilaçMajör

    Patients should be monitored for the emergence of serotonin syndrome, especially with concomitant use of Ondansetron Injection and other serotonergic drugs. (Ondansetron etiketi, Uyarılar ve önlemler)

  • Orfenadrinkas gevşeticiMajör

    John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (Selejilin etiketi, Kontrendikasyonlar)

  • Orfenadrin, aspirin ve kafeinkas gevşeticiMajör

    John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (Selejilin etiketi, Kontrendikasyonlar)

  • Palonosetronserotonerjik ilaçMajör

    Patients should be monitored for the emergence of serotonin syndrome, especially with concomitant use of POSFREA and other serotonergic drugs. (Palonosetron etiketi, Uyarılar ve önlemler)

  • ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • ParoksetinSSRIMajör

    • May cause serotonin syndrome when used with antidepressants (5.2) (Selejilin etiketi, Uyarılar ve önlemler)

  • ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • PetidinopioidMajör

    ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • Prometazin ve dekstrometorfanantihistaminikMajör

    • Concomitant use of dextromethorphan, because of reported episodes of psychosis or bizarre behavior. (Selejilin etiketi, Kontrendikasyonlar)

  • ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • Protriptilintrisiklik antidepresanMajör

    John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (Selejilin etiketi, Kontrendikasyonlar)

  • PsödoefedrindekonjestanMajör

    Warnings Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. (Psödoefedrin etiketi, Uyarılar)

  • RasajilinMAO inhibitörüMajör

    …serotonin reuptake inhibitors-SSRIs, serotonin-norepinephrine reuptake inhibitors-SNRIs, tricyclic antidepressants, tetracyclic antidepressants, triazolopyridine antidepressants) and a non-selective MAOI (e.g., phenelzine, tranylcypromine) or selective MAO-B inhibitors, such as selegiline (ELDEPRYL), rasagiline (AZILECT), and olanzapine (Zydis) selegiline (ZELAPAR). (Selejilin etiketi, Uyarılar ve önlemler)

  • RemifentanilopioidMajör

    ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • RizatriptantriptanMajör

    Monoamine Oxidase Inhibitors MAXALT is contraindicated in patients taking MAO-A inhibitors and non-selective MAO inhibitors. (Rizatriptan etiketi, İlaç etkileşimleri)

  • Sarı kantaronBitkisel ürün ve takviyeMajör

    Sarı kantaronun antidepresanlarla ve diğer serotonerjik ilaçlarla birlikte alınması serotonin sendromu riskini artırır. (NCCIH, St. John's Wort)

  • SertralinSSRIMajör

    • May cause serotonin syndrome when used with antidepressants (5.2) (Selejilin etiketi, Uyarılar ve önlemler)

  • Siklobenzaprinkas gevşeticiMajör

    John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (Selejilin etiketi, Kontrendikasyonlar)

  • SiproheptadinantihistaminikMajör

    Monoamine oxidase inhibitor therapy (See DRUG INTERACTIONS ). (Siproheptadin etiketi, Kontrendikasyonlar)

  • SitalopramSSRIMajör

    • May cause serotonin syndrome when used with antidepressants (5.2) (Selejilin etiketi, Uyarılar ve önlemler)

  • SolriamfetolMSS uyarıcısıMajör

    SUNOSI is contraindicated in patients receiving concomitant treatment with monoamine oxidase (MAO) inhibitors, or within 14 days following discontinuation of monoamine oxidase inhibitor, because of the risk of hypertensive reaction [see Drug Interactions ( 7.1 )] . (Solriamfetol etiketi, Kontrendikasyonlar)

  • SumatriptantriptanMajör

    Selective Serotonin Reuptake Inhibitors/Serotonin Norepinephrine Reuptake Inhibitors and Serotonin Syndrome Cases of serotonin syndrome have been reported during coadministration of triptans and SSRIs, SNRIs, TCAs, and MAO inhibitors [see Warnings and Precautions (5.7)] . (Sumatriptan etiketi, İlaç etkileşimleri)

  • Selective Serotonin Reuptake Inhibitors/Serotonin Norepinephrine Reuptake Inhibitors and Serotonin Syndrome Clinical Impact: Cases of serotonin syndrome have been reported during coadministration of triptans and SSRIs, SNRIs, TCAs, and MAO inhibitors [see Warnings and Precautions (5.11)] . (Sumatriptan ve naproksen etiketi, İlaç etkileşimleri)

  • TapentadolopioidMajör

    ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • TetrabenazinVMAT2 inhibitörüMajör

    • Taking monoamine oxidase inhibitors (MAOIs). (Tetrabenazin etiketi, Kontrendikasyonlar)

  • Tizanidinkas gevşeticiMajör

    John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (Selejilin etiketi, Kontrendikasyonlar)

  • TramadolopioidMajör

    ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • ZELAPAR is contraindicated in patients with: • Concomitant use of opioid drugs (e.g., meperidine, tramadol, or methadone). (Selejilin etiketi, Kontrendikasyonlar)

  • TranilsiprominMAO inhibitörüMajör

    …serotonin reuptake inhibitors-SSRIs, serotonin-norepinephrine reuptake inhibitors-SNRIs, tricyclic antidepressants, tetracyclic antidepressants, triazolopyridine antidepressants) and a non-selective MAOI (e.g., phenelzine, tranylcypromine) or selective MAO-B inhibitors, such as selegiline (ELDEPRYL), rasagiline (AZILECT), and olanzapine (Zydis) selegiline (ZELAPAR). (Selejilin etiketi, Uyarılar ve önlemler)

  • TrazodonantidepresanMajör

    • May cause serotonin syndrome when used with antidepressants (5.2) (Selejilin etiketi, Uyarılar ve önlemler)

  • Trimipramintrisiklik antidepresanMajör

    John’s wort or cyclobenzaprine (a tricyclic muscle relaxant). (Selejilin etiketi, Kontrendikasyonlar)

  • ValbenazinVMAT2 inhibitörüMajör

    Dose adjustments due to drug interactions ( 2.4 , 7.1 ): Factors Dose Adjustments for INGREZZA and INGREZZA SPRINKLE Use of MAOIs with INGREZZA or INGREZZA SPRINKLE Avoid concomitant use with MAOIs. (Valbenazin etiketi, İlaç etkileşimleri)

  • VenlafaksinSNRIMajör

    • May cause serotonin syndrome when used with antidepressants (5.2) (Selejilin etiketi, Uyarılar ve önlemler)

  • VilazodonSSRIMajör

    • May cause serotonin syndrome when used with antidepressants (5.2) (Selejilin etiketi, Uyarılar ve önlemler)

  • Viloksazinnoradrenalin geri alım inhibitörüMajör

    Qelbree is contraindicated in patients: receiving concomitant treatment with monoamine oxidase inhibitors (MAOI), or within 14 days following discontinuing an MAOI, because of an increased risk of hypertensive crisis [see Drug Interactions (7.1) ] . receiving concomitant administration of sensitive CYP1A2 substrates or CYP1A2 substrates with a narrow therapeutic… (Viloksazin etiketi, Kontrendikasyonlar)

  • VortioksetinantidepresanMajör

    • May cause serotonin syndrome when used with antidepressants (5.2) (Selejilin etiketi, Uyarılar ve önlemler)

  • ZiprasidonantipsikotikMajör

    • Concomitant use of monoamine oxidase inhibitors (MAOIs), or use within 14 days of stopping MAOIs. (Ziprasidon etiketi, Kontrendikasyonlar)

Orta düzey etkileşimler (120)

  • AdrenalinsempatomimetikOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • AmantadinantikolinerjikOrta

    Dyskinesia ZELAPAR may potentiate dopaminergic side effects of levodopa and may cause dyskinesia or exacerbate preexisting dyskinesia. (Selejilin etiketi, Uyarılar ve önlemler)

  • AprepitantCYP3A4 inhibitörüOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • Arformoterolbeta adrenerjik agonistOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • AripiprazolantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • ArmodafinilMSS uyarıcısıOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • Artikain ve adrenalinlokal anestezikOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • AsenapinantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • BosentanCYP3A4 indükleyicisiOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • BrekspiprazolantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • Brimonidinalfa adrenerjik agonistOrta

    Monoamine oxidase inhibitors may result in increased hypotension. (Brimonidin etiketi, İlaç etkileşimleri)

  • Brimonidin ve timololalfa adrenerjik agonistOrta

    Monoamine oxidase inhibitors may result in increased hypotension. (Brimonidin ve timolol etiketi, İlaç etkileşimleri)

  • Bromokriptindopamin agonistiOrta

    Dyskinesia ZELAPAR may potentiate dopaminergic side effects of levodopa and may cause dyskinesia or exacerbate preexisting dyskinesia. (Selejilin etiketi, Uyarılar ve önlemler)

  • Budesonid ve formoterolkortikosteroidOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • Bupivakainlokal anestezikOrta

    …of Adverse Reactions Due to Drug Interactions with MARCAINE WITH EPINEPHRINE Risk of Severe, Persistent Hypertension Due to Drug Interactions Between MARCAINE WITH EPINEPHRINE and Monoamine Oxidase Inhibitors and Tricyclic Antidepressants Administration of MARCAINE WITH EPINEPHRINE (containing a vasoconstrictor) in patients receiving monoamine oxidase inhibitors… (Bupivakain etiketi, Uyarılar ve önlemler)

  • Bupivakain ve adrenalinlokal anestezikOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • Drug Interactions The CNS effects of butalbital may be enhanced by monoamine oxidase (MAO) inhibitors. (Butalbital ve parasetamol etiketi, İlaç etkileşimleri)

  • Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • Deferasiroksdemir takviyesiOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • DeksametazonkortikosteroidOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • DiazepambenzodiazepinOrta

    …be given to the pharmacology of the agents employed particularly with compounds that may potentiate or be potentiated by the action of Valium, such as phenothiazines, antipsychotics, anxiolytics/sedatives, hypnotics, anticonvulsants, narcotic analgesics, anesthetics, sedative antihistamines, narcotics, barbiturates, MAO inhibitors and other antidepressants. (Diazepam etiketi, İlaç etkileşimleri)

  • DifenhidraminantihistaminikOrta

    MAO inhibitors prolong and intensify the anticholinergic (drying) effects of antihistamines. (Difenhidramin etiketi, İlaç etkileşimleri)

  • DisikloverinantikolinerjikOrta

    …drugs including dicyclomine hydrochloride: amantadine, antiarrhythmic agents of Class I (e.g., quinidine), antihistamines, antipsychotic agents (e.g., phenothiazines), benzodiazepines, MAO inhibitors, narcotic analgesics (e.g., meperidine), nitrates and nitrites, sympathomimetic agents, tricyclic antidepressants, and other drugs having anticholinergic activity. (Disikloverin etiketi, İlaç etkileşimleri)

  • DobutaminsempatomimetikOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • Droperidoldopamin antagonistiOrta

    …1) clinically significant bradycardia (less than 50 bpm), 2) any clinically significant cardiac disease, 3) treatment with Class I and Class III antiarrhythmics, 4) treatment with monoamine oxidase inhibitors (MAOI's), 5) concomitant treatment with other drug products known to prolong the QT interval (see PRECAUTIONS, Drug Interactions ), and 6) electrolyte imbalance,… (Droperidol etiketi, Uyarılar)

  • EfavirenzantiretroviralOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • EfedrinsempatomimetikOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • Ergotamin ve kafeinergot alkaloidiOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • EslikarbazepinantikonvülsanOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • EstazolambenzodiazepinOrta

    The action of the benzodiazepines may be potentiated by anticonvulsants, antihistamines, alcohol, barbiturates, monoamine oxidase inhibitors, narcotics, phenothiazines, psychotropic medications, or other drugs that produce CNS depression. (Estazolam etiketi, İlaç etkileşimleri)

  • EtravirinantiretroviralOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • FenilefrindekonjestanOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • FenitoinantikonvülsanOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • FenobarbitalbarbitüratOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • FlufenazinantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • Flutikazon ve salmeterolkortikosteroidOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • Formoterolbeta adrenerjik agonistOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • FosfenitoinantikonvülsanOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • GlibenklamidsülfonilüreOrta

    …Interactions The hypoglycemic action of sulfonylureas may be potentiated by certain drugs including nonsteroidal anti-inflammatory agents, ACE inhibitors, disopyramide, fluoxetine, clarithromycin, and other drugs that are highly protein bound, salicylates, sulfonamides, chloramphenicol, probenecid, monoamine oxidase inhibitors, and beta adrenergic blocking agents. (Glibenklamid etiketi, İlaç etkileşimleri)

  • GlimepiridsülfonilüreOrta

    …steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides, chloramphenicol, coumarins, probenecid and monoamine oxidase inhibitors. (Glimepirid etiketi, İlaç etkileşimleri)

  • GlipizidsülfonilüreOrta

    …increase the susceptibility to and/or intensity of hypoglycemia: antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analogs (e.g., octreotide), sulfonamide antibiotics, nonsteroidal anti-inflammatory… (Glipizid etiketi, İlaç etkileşimleri)

  • Glipizid ve metforminsülfonilüreOrta

    Glipizide: The hypoglycemic action of sulfonylureas may be potentiated by certain drugs, including nonsteroidal anti-inflammatory agents, some azoles, and other drugs that are highly protein bound, salicylates, sulfonamides, chloramphenicol, probenecid, coumarins, monoamine oxidase inhibitors, and beta-adrenergic blocking agents. (Glipizid ve metformin etiketi, Önlemler)

  • GriseofulvinantifungalOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • HaloperidolantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • HidralazinvazodilatörOrta

    Drug Interactions MAO inhibitors should be used with caution in patients receiving hydralazine. (Hidralazin etiketi, İlaç etkileşimleri)

  • İloperidonantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • İnsülin aspartinsülinOrta

    Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analog (e.g., octreotide), and sulfonamide antibiotics. (İnsülin aspart etiketi, İlaç etkileşimleri)

  • İnsülin degludekinsülinOrta

    …Degludec Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors,… (İnsülin degludek etiketi, İlaç etkileşimleri)

  • İnsülin detemirinsülinOrta

    …with LEVEMIR Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors,… (İnsülin detemir etiketi, İlaç etkileşimleri)

  • İnsülin glarjininsülinOrta

    …Glargine-yfgn Drugs that May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors,… (İnsülin glarjin etiketi, İlaç etkileşimleri)

  • İnsülin lisproinsülinOrta

    Clinically Significant Drug Interactions with LYUMJEV Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics. (İnsülin lispro etiketi, İlaç etkileşimleri)

  • İpratropium ve salbutamolantikolinerjikOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • İzoflurangenel anestezikOrta

    Concomitant Use with MAO Inhibitors Concomitant use of MAO inhibitors and inhalational anesthetics may increase the risk of hemodynamic instability during surgery or medical procedures. (İzofluran etiketi, İlaç etkileşimleri)

  • İzoprenalinbeta adrenerjik agonistOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • Kabergolindopamin agonistiOrta

    Dyskinesia ZELAPAR may potentiate dopaminergic side effects of levodopa and may cause dyskinesia or exacerbate preexisting dyskinesia. (Selejilin etiketi, Uyarılar ve önlemler)

  • KariprazinantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • Karvedilolbeta blokerOrta

    Hypotensive agents (e.g., reserpine, MAO inhibitors, clonidine) may increase the risk of hypotension and/or severe bradycardia. (Karvedilol etiketi, İlaç etkileşimleri)

  • KetiapinantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • KlemastinantihistaminikOrta

    Monoamine oxidase (MAO) inhibitors prolong and intensify the anticholinergic effects of antihistamines. (Klemastin etiketi, İlaç etkileşimleri)

  • KlobazambenzodiazepinOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • KlonazepambenzodiazepinOrta

    …Interactions The CNS-depressant action of the benzodiazepine class of drugs may be potentiated by alcohol, narcotics, barbiturates, nonbarbiturate hypnotics, antianxiety agents, the phenothiazines, thioxanthene and butyrophenone classes of antipsychotic agents, monoamine oxidase inhibitors and the tricyclic antidepressants, and by other anticonvulsant drugs. (Klonazepam etiketi, İlaç etkileşimleri)

  • KlorazepatbenzodiazepinOrta

    The actions of the benzodiazepines may be potentiated by barbiturates, narcotics, phenothiazines, monoamine oxidase inhibitors or other antidepressants. (Klorazepat etiketi, İlaç etkileşimleri)

  • Kloroprokainlokal anestezikOrta

    Drug Interactions The administration of local anesthetic solutions containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors, tricyclic antidepressants or phenothiazines may produce severe, prolonged hypotension or hypertension. (Kloroprokain etiketi, Önlemler)

  • KlorpromazinantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • KlozapinantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • Kokainlokal anestezikOrta

    Monoamine-oxidase inhibitors: Concomitant administration may potentiate the effects and toxicity of monoamine-oxidase inhibitors. (Kokain etiketi, İlaç etkileşimleri)

  • Levosalbutamolbeta adrenerjik agonistOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • Lidokainlokal anestezikOrta

    Clinically Significant Drug Interactions The administration of local anesthetic solutions containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors or tricyclic antidepressants may produce severe, prolonged hypertension. (Lidokain etiketi, İlaç etkileşimleri)

  • Lidokain ve adrenalinlokal anestezikOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • LoksapinantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • Lopinavir ve ritonavirantiretroviralOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • LorlatinibCYP3A4 indükleyicisiOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • LumateperonantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • LurasidonantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • Mepivakainlokal anestezikOrta

    Likewise, solutions of mepivacaine containing a vasoconstrictor, such as epinephrine, should be used with extreme caution in patients receiving monoamine oxidase inhibitors (MAOI) or antidepressants of the triptyline or imipramine types, because severe prolonged hypertension may result. (Mepivakain etiketi, Uyarılar)

  • Metoprololbeta blokerOrta

    Catecholamine depleting drugs (e.g., reserpine, monoamine oxidase (MAO) inhibitors) may have an additive effect when given with beta-blocking agents. (Metoprolol etiketi, İlaç etkileşimleri)

  • Catecholamine-depleting drugs (e.g., MAO inhibitors): Hypotension, bradycardia. (Metoprolol ve hidroklorotiyazid etiketi, İlaç etkileşimleri)

  • Mirabegronbeta adrenerjik agonistOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • MitapivatCYP3A4 indükleyicisiOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • MitotanCYP3A4 indükleyicisiOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • ModafinilMSS uyarıcısıOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • Nafsilinpenisilin antibiyotikOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • NateglinidmeglitinidOrta

    …Nateglinide Drugs That May Increase the Blood-Glucose-Lowering Effect of Nateglinide and Susceptibility to Hypoglycemia Drugs: Nonsteroidal anti-inflammatory drugs (NSAIDs), salicylates, monoamine oxidase inhibitors, non-selective beta-adrenergic-blocking agents, anabolic hormones (e.g., methandrostenolone), guanethidine, gymnema sylvestre, glucomannan, thioctic acid,… (Nateglinid etiketi, İlaç etkileşimleri)

  • NevirapinantiretroviralOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • OksimetazolindekonjestanOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • OkskarbazepinantikonvülsanOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • PaliperidonantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • PerfenazinantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • PimavanserinantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • PimozidantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • Pioglitazon ve glimepiridtiyazolidindionOrta

    …steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides, chloramphenicol, coumarins, probenecid and monoamine oxidase inhibitors. (Pioglitazon ve glimepirid etiketi, İlaç etkileşimleri)

  • Pramipeksoldopamin agonistiOrta

    Dyskinesia ZELAPAR may potentiate dopaminergic side effects of levodopa and may cause dyskinesia or exacerbate preexisting dyskinesia. (Selejilin etiketi, Uyarılar ve önlemler)

  • Prilokain ve adrenalinlokal anestezikOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • PrimidonantikonvülsanOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • ProklorperazinantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • PrometazinantihistaminikOrta

    Monoamine Oxidase Inhibitors (MAOI) Drug interactions, including an increased incidence of extrapyramidal effects, have been reported when some MAOI and phenothiazines are used concomitantly. (Prometazin etiketi, İlaç etkileşimleri)

  • …Significant Drug Interactions with AFREZZA Antidiabetic agents, Angiotensin-Converting Enzyme Inhibitors, Angiotensin II Receptor Blocking Agents, Disopyramide, Fibrates, Fluoxetine, Monoamine Oxidase Inhibitors, Pentoxifylline, Pramlintide, Salicylates, Somatostatin Analogs (e.g., octreotide), and Sulfonamide Antibiotics Prevention or Management Monitor blood glucose… (Regüler insülin (insan) etiketi, İlaç etkileşimleri)

  • RifabutinantibiyotikOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • RifampisinantibiyotikOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • RifapentinantibiyotikOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • RisperidonantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • RitonavirantiretroviralOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • Ropiniroldopamin agonistiOrta

    Dyskinesia ZELAPAR may potentiate dopaminergic side effects of levodopa and may cause dyskinesia or exacerbate preexisting dyskinesia. (Selejilin etiketi, Uyarılar ve önlemler)

  • Salbutamolbeta adrenerjik agonistOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • Salmeterolbeta adrenerjik agonistOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • SenobamatantikonvülsanOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • Sevoflurangenel anestezikOrta

    Non-selective MAO-inhibitors Concomitant use of MAO inhibitors and inhalational anesthetics may increase the risk of hemodynamic instability during surgery or medical procedures. (Sevofluran etiketi, İlaç etkileşimleri)

  • SuzetrijinCYP3A4 indükleyicisiOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • Süksinilkolinnöromüsküler blokerOrta

    The neuromuscular blocking effect of succinylcholine may be enhanced by drugs that reduce plasma cholinesterase activity (e.g., chronically administered oral contraceptives, glucocorticoids, or certain monoamine oxidase inhibitors) or by drugs that irreversibly inhibit plasma cholinesterase [see Warnings and Precautions (5.9) ]. (Süksinilkolin etiketi, İlaç etkileşimleri)

  • Terbutalinbeta adrenerjik agonistOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • TioridazinantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • TiotiksenantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • Baseline treatment with dopamine agonists or selegiline did not appear to increase the likelihood of experiencing orthostatic hypotension when treated with Tolcapone tablets. (Tolkapon etiketi, Önlemler)

  • TopiramatantikonvülsanOrta

    Drugs that induce CYP3A4 (e.g., phenytoin, carbamazepine, nafcillin, phenobarbital, and rifampin) should be used with caution. (Selejilin etiketi, İlaç etkileşimleri)

  • TrifluoperazinantipsikotikOrta

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (Selejilin etiketi, Uyarılar ve önlemler)

  • Umeklidinyum ve vilanterolantikolinerjikOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

  • Vibegronbeta adrenerjik agonistOrta

    Uncontrolled hypertension has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication (ephedrine). (Selejilin etiketi, Uyarılar ve önlemler)

Minör değinmeler (8)

  • Drug Interactions Since the chemical structure of difenoxin hydrochloride is similar to meperidine hydrochloride, the concurrent use of MOTOFEN ® with monoamine oxidase inhibitors may, in theory, precipitate a hypertensive crisis. (Difenoksin ve atropin etiketi, İlaç etkileşimleri)

  • EntakaponMinör

    Entacapone can be taken concomitantly with a selective MAO-B inhibitor (e.g., selegiline). (Entakapon etiketi, Uyarılar)

  • Glibenklamid ve metforminsülfonilüreMinör

    Examples: Nonsteroidal anti-inflammatory agents and other highly protein-boind drugs, salicylcates, sulfonamides, chloramphenicol, probenecid, coumarins, monoamine oxidase inhibitors, beta-adrenergic blocking agents; potentially with ciprofloxacin, micronazole. (Glibenklamid ve metformin etiketi, İlaç etkileşimleri)

  • Propranololbeta blokerMinör

    Antidepressants: The hypotensive effect of MAO inhibitors or tricyclic antidepressants may be exacerbated when administered with beta-blockers. (Propranolol etiketi, İlaç etkileşimleri)

  • RepaglinidmeglitinidMinör

    Examples: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, nonsteroidal anti-inflammatory agents (NSAIDs), pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics. (Repaglinid etiketi, İlaç etkileşimleri)

  • TerbinafinantifungalMinör

    Drugs predominantly metabolized by the CYP450 2D6 isozyme include the following drug classes: tricyclic antidepressants, selective serotonin reuptake inhibitors, beta-blockers, antiarrhythmics class 1C (e.g., flecainide and propafenone) and monoamine oxidase inhibitors Type B. (Terbinafin etiketi, İlaç etkileşimleri)

  • TriheksifenidilantikolinerjikMinör

    Monoamine oxidase inhibitors and tricyclic antidepressants possessing significant anticholinergic activity may intensify the anticholinergic effects of antidyskinetic agents because of the secondary anticholinergic activities of these medications. (Triheksifenidil etiketi, İlaç etkileşimleri)

  • ZolmitriptantriptanMinör

    Serotonin Syndrome Serotonin syndrome may occur with triptans, including zolmitriptan, particularly during co-administration with selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), and MAO inhibitors [see Drug Interactions ( 7.5 )] . (Zolmitriptan etiketi, Uyarılar ve önlemler)

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Tıbbi tavsiye değildir. Şiddet derecesi sizin koşullarınızı değil, etiketin ifadesini yansıtır. “Majör” işareti gözetim altında olağan bir uygulama olabilir, “minör” işareti ise yüksek dozlarda önem kazanabilir. Bir eczacıya danışın.