Sertralin etkileşimleri

SSRI sınıfından Sertralin (Zoloft) için dizinlediğimiz FDA etiketlerinde ve bilgi sayfalarında 351 belgelenmiş etkileşim var: 149 majör, 164 orta, 31 minör ve bir etiketin anlamlı etkileşim olmadığını bildirdiği 7 çift. Aşağıdaki her kayıt, dayandığı cümleyi alıntılar. Bu ilaç sayfası bir başlangıç noktasıdır; sizin durumunuz için verilmiş bir hüküm değildir.

Sertralin, Zoloft adıyla ve yaygın olarak jenerik biçimde satılan bir SSRI antidepresandır. Beyinde kullanılabilir serotonin miktarını artırır. Majör depresyon, obsesif kompulsif bozukluk, panik bozukluğu, travma sonrası stres bozukluğu, sosyal anksiyete bozukluğu ve premenstrüel disforik bozukluk için onaylıdır. Tablet veya kullanılmadan önce seyreltilen oral konsantre olarak bulunur ve genellikle günde bir kez, sabah veya akşam, aç veya tok karnına alınır.

Etikete göre etkileşimler

Majör etkileşimler (149)

  • Alfuzosinalfa blokerMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • AlmotriptantriptanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • AmfetaminMSS uyarıcısıMajör

    Serotonin Syndrome: Increased risk when co-administered with serotonergic agents (e.g., SSRIs, SNRIs, triptans), but also during overdosage situations. (Amfetamin etiketi, Uyarılar ve önlemler)

  • Amfetamin ve dekstroamfetaminMSS uyarıcısıMajör

    Serotonin Syndrome: Increased risk when coadministered with serotonergic agents (e.g., selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), triptans), but also during overdosage situations. (Amfetamin ve dekstroamfetamin etiketi, Uyarılar ve önlemler)

  • AmiodaronantiaritmikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • Amitriptilintrisiklik antidepresanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • Amoksapintrisiklik antidepresanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • AnagrelidQT aralığını uzatan ilaçMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • Arsenik trioksitQT aralığını uzatan ilaçMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • AsenapinantipsikotikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • Azitromisinmakrolid antibiyotikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • • Serotonergic Drugs: Concomitant use may result in serotonin syndrome. (Belladonna ve afyon etiketi, İlaç etkileşimleri)

  • Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • BuprenorfinopioidMajör

    Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (Buprenorfin etiketi, İlaç etkileşimleri)

  • Serotonergic Drugs: Concomitant use may result in serotonin syndrome. (Buprenorfin ve nalokson etiketi, İlaç etkileşimleri)

  • Buspironserotonerjik ilaçMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • Intervention: Avoid concomitant use Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (Butalbital, aspirin, kafein ve kodein etiketi, İlaç etkileşimleri)

  • • Serotonergic Drugs: Concomitant use may result in serotonin syndrome. (Butalbital, parasetamol, kafein ve kodein etiketi, İlaç etkileşimleri)

  • ButorfanolopioidMajör

    …medical attention if they ‎experience symptoms of hyperalgesia, including worsening pain, increased ‎sensitivity to pain, or new pain [see WARNINGS ; ADVERSE REACTIONS ].‎ Serotonin Syndrome Inform patients that butorphanol tartrate could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (Butorfanol etiketi, Önlemler)

  • DekstroamfetaminMSS uyarıcısıMajör

    Serotonergic Drugs The concomitant use of dextroamphetamine sulfate and serotonergic drugs increases the risk of serotonin syndrome. (Dekstroamfetamin etiketi, İlaç etkileşimleri)

  • Dekstrometorfanserotonerjik ilaçMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • Dekstrometorfan ve kinidinserotonerjik ilaçMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • Desipramintrisiklik antidepresanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • DesvenlafaksinSNRIMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • Dihidroergotaminergot alkaloidiMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • DisopiramidantiaritmikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • DofetilidantiaritmikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • Doksepintrisiklik antidepresanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • DötetrabenazinVMAT2 inhibitörüMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • DronedaronantiaritmikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • Droperidoldopamin antagonistiMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • DuloksetinSNRIMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • EdoksabanantikoagülanMajör

    Anticoagulants, Antiplatelets, Thrombolytics, and Selective Serotonin Reuptake Inhibitors (SSRIs)/Serotonin Norepinephrine Reuptake Inhibitors (SNRIs): Avoid concomitant use due to increased risk of bleeding. (Edoksaban etiketi, İlaç etkileşimleri)

  • EletriptantriptanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • Eritromisinmakrolid antibiyotikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • EssitalopramSSRIMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • FenelzinMAO inhibitörüMajör

    Sertraline hydrochloride capsules are contraindicated in patients: Taking, or within 14 days of stopping, MAOIs, (including the MAOIs linezolid and intravenous methylene blue) because of an increased risk of serotonin syndrome [see Warnings and Precautions ( 5.2 ), Drug Interactions ( 7.1 )] . (Sertralin etiketi, Kontrendikasyonlar)

  • FentanilopioidMajör

    • Serotonin Syndrome : Potentially life-threatening condition could result from concomitant serotonergic drug administration. (Fentanil etiketi, Uyarılar ve önlemler)

  • FingolimodimmünosüpresanMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • FlekainidantiaritmikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • FlibanserinMSS depresanıMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • Flukonazolazol antifungalMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • FlumazenilbenzodiazepinMajör

    THESE ARE MOST FREQUENT IN PATIENTS WHO HAVE BEEN ON BENZODIAZEPINES FOR LONG-TERM SEDATION OR IN OVERDOSE CASES WHERE PATIENTS ARE SHOWING SIGNS OF SERIOUS CYCLIC ANTIDEPRESSANT OVERDOSE. (Flumazenil etiketi, Kutulu uyarı)

  • FluoksetinSSRIMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • FluvoksaminSSRIMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • FrovatriptantriptanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • GranisetronQT aralığını uzatan ilaçMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • HaloperidolantipsikotikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • HidrokodonopioidMajör

    Example: lactulose Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (Hidrokodon etiketi, İlaç etkileşimleri)

  • Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (Hidrokodon ve homatropin etiketi, İlaç etkileşimleri)

  • S er otonin Syndrome Inform patients that opioids could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (Hidrokodon ve ibuprofen etiketi, Önlemler)

  • Serotonergic drugs : Concomitant use may result in serotonin syndrome. (Hidrokodon ve klorfeniramin etiketi, İlaç etkileşimleri)

  • Serotonin Syndrome Inform patients that hydrocodone bitartrate and acetaminophen tablets could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (Hidrokodon ve parasetamol etiketi, Önlemler)

  • HidroksiklorokinQT aralığını uzatan ilaçMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • HidroksizinantihistaminikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • HidromorfonopioidMajör

    • Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (Hidromorfon etiketi, İlaç etkileşimleri)

  • İbutilidantiaritmikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • İloperidonantipsikotikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • İmipramintrisiklik antidepresanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • İzoniazidantibiyotikMajör

    Sertraline hydrochloride capsules are contraindicated in patients: Taking, or within 14 days of stopping, MAOIs, (including the MAOIs linezolid and intravenous methylene blue) because of an increased risk of serotonin syndrome [see Warnings and Precautions ( 5.2 ), Drug Interactions ( 7.1 )] . (Sertralin etiketi, Kontrendikasyonlar)

  • KarbamazepinantikonvülsanMajör

    Known hypersensitivity to tricyclic antidepressants ( 4 ) (Karbamazepin etiketi, Kontrendikasyonlar)

  • KetiapinantipsikotikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • Ketokonazolazol antifungalMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • KinidinantiaritmikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • KininantimalaryalMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • Klaritromisinmakrolid antibiyotikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • Klomipramintrisiklik antidepresanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • KlorokinantimalaryalMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • KlorpromazinantipsikotikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • KlozapinantipsikotikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • KodeinopioidMajör

    • Serotonergic Drugs: Concomitant use may result in serotonin syndrome. (Kodein etiketi, İlaç etkileşimleri)

  • LevofloksasinflorokinolonMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • LevomilnasipranSNRIMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • LevorfanolopioidMajör

    Serotonin Syndrome Inform patients that opioids could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (Levorfanol etiketi, Önlemler)

  • LinezolidantibiyotikMajör

    Sertraline hydrochloride capsules are contraindicated in patients: Taking, or within 14 days of stopping, MAOIs, (including the MAOIs linezolid and intravenous methylene blue) because of an increased risk of serotonin syndrome [see Warnings and Precautions ( 5.2 ), Drug Interactions ( 7.1 )] . (Sertralin etiketi, Kontrendikasyonlar)

  • LisdeksamfetaminMSS uyarıcısıMajör

    Serotonin Syndrome: Increased risk when co-administered with serotonergic agents (e.g., SSRIs, SNRIs, triptans), but also during overdosage situations. (Lisdeksamfetamin etiketi, Uyarılar ve önlemler)

  • Lityumserotonerjik ilaçMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • LoperamidQT aralığını uzatan ilaçMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • LorazepambenzodiazepinMajör

    LOREEV XR should not be used in such patients without adequate antidepressant therapy. (Lorazepam etiketi, Uyarılar ve önlemler)

  • MetadonopioidMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • Metaksalonkas gevşeticiMajör

    Serotonin syndrome has resulted from concomitant use of metaxalone (within the recommended dosage range) and other serotonergic drugs [see Warnings and Precautions (5.1) ]. (Metaksalon etiketi, İlaç etkileşimleri)

  • MetamfetaminMSS uyarıcısıMajör

    Serotonin Syndrome: Increased risk when coadministered with serotonergic agents (e.g., SSRIs, SNRIs, triptans), but also during overdosage situations. (Metamfetamin etiketi, Uyarılar ve önlemler)

  • Metilen mavisiMAO inhibitörüMajör

    Sertraline hydrochloride capsules are contraindicated in patients: Taking, or within 14 days of stopping, MAOIs, (including the MAOIs linezolid and intravenous methylene blue) because of an increased risk of serotonin syndrome [see Warnings and Precautions ( 5.2 ), Drug Interactions ( 7.1 )] . (Sertralin etiketi, Kontrendikasyonlar)

  • MilnasipranSNRIMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • MirtazapinantidepresanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • MoksifloksasinflorokinolonMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • MorfinopioidMajör

    • Serotonergic Drugs: Concomitant use may result in serotonin syndrome. (Morfin etiketi, İlaç etkileşimleri)

  • NaratriptantriptanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • NefazodonantidepresanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • NilotinibQT aralığını uzatan ilaçMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • Nortriptilintrisiklik antidepresanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • OfloksasinflorokinolonMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • OksikodonopioidMajör

    Serotonergic Drug s: Concomitant use may result in serotonin syndrome. (Oksikodon etiketi, İlaç etkileşimleri)

  • OksimorfonopioidMajör

    Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (Oksimorfon etiketi, İlaç etkileşimleri)

  • Olanzapin ve fluoksetinantipsikotikMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • OliseridinopioidMajör

    Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (Oliseridin etiketi, İlaç etkileşimleri)

  • OndansetronQT aralığını uzatan ilaçMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • PaliperidonantipsikotikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • Palonosetronserotonerjik ilaçMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • Serotonin Syndrome Inform patients that opioids could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (Parasetamol ve kodein etiketi, Önlemler)

  • ParoksetinSSRIMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • PentamidinQT aralığını uzatan ilaçMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • Serotonin Syndrome Inform patients that opioids could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (Pentazosin ve nalokson etiketi, Önlemler)

  • PetidinopioidMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • PimavanserinantipsikotikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • PimozidantipsikotikMajör

    Taking pimozide [see Drug Interactions ( 7.1 )] . (Sertralin etiketi, Kontrendikasyonlar)

  • PitolisantQT aralığını uzatan ilaçMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • Posakonazolazol antifungalMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • ProkainamidantiaritmikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • PrometazinantihistaminikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • Prometazin ve dekstrometorfanantihistaminikMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • Protriptilintrisiklik antidepresanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • Prukalopridserotonerjik ilaçMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • RanolazinQT aralığını uzatan ilaçMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • RasajilinMAO inhibitörüMajör

    Sertraline hydrochloride capsules are contraindicated in patients: Taking, or within 14 days of stopping, MAOIs, (including the MAOIs linezolid and intravenous methylene blue) because of an increased risk of serotonin syndrome [see Warnings and Precautions ( 5.2 ), Drug Interactions ( 7.1 )] . (Sertralin etiketi, Kontrendikasyonlar)

  • RemifentanilopioidMajör

    • Serotonin Syndrome : Potentially life-threatening condition could result from concomitant serotonergic drug administration. (Remifentanil etiketi, Uyarılar ve önlemler)

  • RisperidonantipsikotikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • RizatriptantriptanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • Sarı kantaronBitkisel ürün ve takviyeMajör

    Sarı kantaronun antidepresanlarla ve diğer serotonerjik ilaçlarla birlikte alınması serotonin sendromu riskini artırır. (NCCIH, St. John's Wort)

  • SelejilinMAO inhibitörüMajör

    Sertraline hydrochloride capsules are contraindicated in patients: Taking, or within 14 days of stopping, MAOIs, (including the MAOIs linezolid and intravenous methylene blue) because of an increased risk of serotonin syndrome [see Warnings and Precautions ( 5.2 ), Drug Interactions ( 7.1 )] . (Sertralin etiketi, Kontrendikasyonlar)

  • Siklobenzaprinkas gevşeticiMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • SiprofloksasinflorokinolonMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • SitalopramSSRIMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • SolifenasinantikolinerjikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • SolriamfetolMSS uyarıcısıMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • Sotalolbeta blokerMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • SumatriptantriptanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • TakrolimusimmünosüpresanMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • Tamoksifenselektif östrojen reseptör modülatörüMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • TapentadolopioidMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • TetrabenazinVMAT2 inhibitörüMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • TioridazinantipsikotikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • TolterodinantikolinerjikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • Toremifenselektif östrojen reseptör modülatörüMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • TramadolopioidMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • TranilsiprominMAO inhibitörüMajör

    Sertraline hydrochloride capsules are contraindicated in patients: Taking, or within 14 days of stopping, MAOIs, (including the MAOIs linezolid and intravenous methylene blue) because of an increased risk of serotonin syndrome [see Warnings and Precautions ( 5.2 ), Drug Interactions ( 7.1 )] . (Sertralin etiketi, Kontrendikasyonlar)

  • TrazodonantidepresanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • Trimipramintrisiklik antidepresanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • ValbenazinVMAT2 inhibitörüMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • VardenafilPDE5 inhibitörüMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • VenlafaksinSNRIMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • VilazodonSSRIMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • Vorikonazolazol antifungalMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • VortioksetinantidepresanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

  • ZiprasidonantipsikotikMajör

    Avoid the concomitant use of drugs known to prolong the QTc interval. (Sertralin etiketi, İlaç etkileşimleri)

  • ZolmitriptantriptanMajör

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (Sertralin etiketi, Uyarılar ve önlemler)

Orta düzey etkileşimler (164)

  • AdrenalinsempatomimetikOrta

    • Drugs that potentiate the effects of epinephrine include sympathomimetics, beta blockers, tricyclic antidepressants, MAO inhibitors, COMT inhibitors, clonidine, doxapram, oxytocin, levothyroxine sodium, and certain antihistamines. (Adrenalin etiketi, İlaç etkileşimleri)

  • Amiloridpotasyum tutucu diüretikOrta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • ApiksabanantikoagülanOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Arformoterolbeta adrenerjik agonistOrta

    MAO inhibitors, tricyclic antidepressants and drugs that prolong the QTc interval may potentiate effect on the cardiovascular system. (Arformoterol etiketi, İlaç etkileşimleri)

  • ArgatrobanantikoagülanOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • ArmodafinilMSS uyarıcısıOrta

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, meperidine, methadone, tryptophan, buspirone, amphetamines, and St. (Sertralin etiketi, Uyarılar ve önlemler)

  • Artikain ve adrenalinlokal anestezikOrta

    The administration of local anesthetic solutions containing epinephrine to patients receiving monoamine oxidase inhibitors, nonselective beta-adrenergic antagonists, or tricyclic antidepressants may produce severe, prolonged hypertension. (Artikain ve adrenalin etiketi, İlaç etkileşimleri)

  • Asetazolamidkarbonik anhidraz inhibitörüOrta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • AspirinNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Aspirin ve dipiridamolantitrombosit ilaçOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • BenzfetaminMSS uyarıcısıOrta

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, meperidine, methadone, tryptophan, buspirone, amphetamines, and St. (Sertralin etiketi, Uyarılar ve önlemler)

  • Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • BivalirudinantikoagülanOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Brimonidinalfa adrenerjik agonistOrta

    Caution is advised in patients taking tricyclic antidepressants which can affect the metabolism and uptake of circulating amines. (Brimonidin etiketi, İlaç etkileşimleri)

  • Brimonidin ve timololalfa adrenerjik agonistOrta

    CYP2D6 Inhibitors Potentiated systemic beta-blockade (e.g., decreased heart rate, depression) has been reported during combined treatment with CYP2D6 inhibitors (e.g., quinidine, SSRIs) and timolol. (Brimonidin ve timolol etiketi, İlaç etkileşimleri)

  • Budesonid ve formoterolkortikosteroidOrta

    Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution. (Budesonid ve formoterol etiketi, İlaç etkileşimleri)

  • Bumetanidkıvrım (loop) diüretiğiOrta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • Bupivakainlokal anestezikOrta

    …Interactions with MARCAINE WITH EPINEPHRINE Risk of Severe, Persistent Hypertension Due to Drug Interactions Between MARCAINE WITH EPINEPHRINE and Monoamine Oxidase Inhibitors and Tricyclic Antidepressants Administration of MARCAINE WITH EPINEPHRINE (containing a vasoconstrictor) in patients receiving monoamine oxidase inhibitors (MAOI) or tricyclic antidepressants may… (Bupivakain etiketi, Uyarılar ve önlemler)

  • Bupivakain ve adrenalinlokal anestezikOrta

    …Interactions with MARCAINE WITH EPINEPHRINE Risk of Severe, Persistent Hypertension Due to Drug Interactions Between MARCAINE WITH EPINEPHRINE and Monoamine Oxidase Inhibitors and Tricyclic Antidepressants Administration of MARCAINE WITH EPINEPHRINE (containing a vasoconstrictor) in patients receiving monoamine oxidase inhibitors (MAOI) or tricyclic antidepressants may… (Bupivakain ve adrenalin etiketi, Uyarılar ve önlemler)

  • BupropionantidepresanOrta

    Drugs Metabolized by CYP2D6: Bupropion inhibits CYP2D6 and can increase concentrations of: antidepressants (e.g., venlafaxine, nortriptyline, imipramine, desipramine, paroxetine, fluoxetine, sertraline), antipsychotics (e.g., haloperidol, risperidone, thioridazine), beta-blockers (e.g., metoprolol), and Type 1C antiarrhythmics (e.g., propafenone, flecainide). (Bupropion etiketi, İlaç etkileşimleri)

  • Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, meperidine, methadone, tryptophan, buspirone, amphetamines, and St. (Sertralin etiketi, Uyarılar ve önlemler)

  • DabigatranantikoagülanOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Daridoreksantsedatif-hipnotikOrta

    Co-administration with other CNS depressants (e.g., benzodiazepines, opioids, tricyclic antidepressants, alcohol) increases the risk of CNS depression, which can cause daytime impairment. (Daridoreksant etiketi, Uyarılar ve önlemler)

  • DarifenasinantikolinerjikOrta

    Caution should be taken when darifenacin extended-release tablets is used concomitantly with medications that are predominantly metabolized by CYP2D6 and which have a narrow therapeutic window, such as flecainide, thioridazine and tricyclic antidepressants ( 7.2 ) (Darifenasin etiketi, İlaç etkileşimleri)

  • DarunavirantiretroviralOrta

    Antidepressants : Selective Serotonin Reuptake Inhibitors (SSRIs): paroxetine, sertraline ↓ paroxetine ↓ sertraline If either sertraline or paroxetine is initiated in patients receiving PREZISTA/ritonavir, dose titrating the SSRI based on a clinical assessment of antidepressant response is recommended. (Darunavir etiketi, İlaç etkileşimleri)

  • Darunavir ve kobisistatantiretroviralOrta

    Antidepressants: Selective Serotonin Reuptake Inhibitors (SSRIs): e.g. paroxetine, sertraline SSRIs: effects unknown When co-administering with SSRIs, TCAs, or trazodone, careful dose titration of the antidepressant to the desired effect, including using the lowest feasible initial or maintenance dose, and monitoring for antidepressant response are recommended. (Darunavir ve kobisistat etiketi, İlaç etkileşimleri)

  • DeksmetilfenidatMSS uyarıcısıOrta

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, meperidine, methadone, tryptophan, buspirone, amphetamines, and St. (Sertralin etiketi, Uyarılar ve önlemler)

  • …that may Increase Risk of Hyponatremia Concomitant administration of DESMODA with other drugs that may increase the risk of water intoxication with hyponatremia, (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, thiazide diuretics, NSAIDs, lamotrigine, sulfonylureas, particularly chlorpropamide, oxybutynin… (Desmopressin etiketi, İlaç etkileşimleri)

  • DiazepambenzodiazepinOrta

    …be given to the pharmacology of the agents employed particularly with compounds that may potentiate or be potentiated by the action of Valium, such as phenothiazines, antipsychotics, anxiolytics/sedatives, hypnotics, anticonvulsants, narcotic analgesics, anesthetics, sedative antihistamines, narcotics, barbiturates, MAO inhibitors and other antidepressants. (Diazepam etiketi, İlaç etkileşimleri)

  • DietilpropionMSS uyarıcısıOrta

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, meperidine, methadone, tryptophan, buspirone, amphetamines, and St. (Sertralin etiketi, Uyarılar ve önlemler)

  • DiflunisalNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • DiklofenakNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Dipiridamolantitrombosit ilaçOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • DisikloverinantikolinerjikOrta

    …drugs including dicyclomine hydrochloride: amantadine, antiarrhythmic agents of Class I (e.g., quinidine), antihistamines, antipsychotic agents (e.g., phenothiazines), benzodiazepines, MAO inhibitors, narcotic analgesics (e.g., meperidine), nitrates and nitrites, sympathomimetic agents, tricyclic antidepressants, and other drugs having anticholinergic activity. (Disikloverin etiketi, İlaç etkileşimleri)

  • Dorzolamid ve timololkarbonik anhidraz inhibitörüOrta

    CYP2D6 Inhibitors Potentiated systemic beta-blockade (e.g., decreased heart rate, depression) has been reported during combined treatment with CYP2D6 inhibitors (e.g., quinidine, SSRIs) and timolol. (Dorzolamid ve timolol etiketi, İlaç etkileşimleri)

  • DronabinolkannabinoidOrta

    Concomitant use of other drugs that cause dizziness, confusion, sedation, or somnolence such as CNS depressants may increase this effect (e.g., barbiturates, benzodiazepines, lithium, opioids, buspirone, scopolamine, antihistamines, tricyclic antidepressants, other anticholinergic agents, and muscle relaxants). (Dronabinol etiketi, Uyarılar ve önlemler)

  • EfavirenzantiretroviralOrta

    Increases in sertraline dosage should be guided by clinical response. (Efavirenz etiketi, İlaç etkileşimleri)

  • Sertraline ↓ sertraline Increases in sertraline dosage should be guided by clinical response. (Efavirenz, lamivudin ve tenofovir etiketi, İlaç etkileşimleri)

  • Antidepressants: Selective Serotonin Reuptake Inhibitors (SSRIs) e.g., paroxetine Tricyclic Antidepressants (TCAs) e.g., amitriptyline desipramine imipramine nortriptyline bupropion trazodone ↑ SSRIs (except sertraline) ↑ TCAs ↑ trazodone Careful dosage titration of the antidepressant and monitoring for antidepressant response are recommended when coadministered… (Elvitegravir, kobisistat, emtrisitabin ve tenofovir etiketi, İlaç etkileşimleri)

  • Enalapril ve hidroklorotiyazidACE inhibitörüOrta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • EnoksaparinantikoagülanOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Eplerenonaldosteron antagonistiOrta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • Eptifibatidantitrombosit ilaçOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Ergotamin ve kafeinergot alkaloidiOrta

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, meperidine, methadone, tryptophan, buspirone, amphetamines, and St. (Sertralin etiketi, Uyarılar ve önlemler)

  • Eszopiklonsedatif-hipnotikOrta

    Additive effects occur with concomitant use of other CNS depressants (e.g., benzodiazepines, opioids, tricyclic antidepressants, alcohol), including daytime use. (Eszopiklon etiketi, Uyarılar ve önlemler)

  • Etakrinik asitkıvrım (loop) diüretiğiOrta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • EtodolakNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • FendimetrazinMSS uyarıcısıOrta

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, meperidine, methadone, tryptophan, buspirone, amphetamines, and St. (Sertralin etiketi, Uyarılar ve önlemler)

  • FenilefrindekonjestanOrta

    Agonistic Effects (increase in BIORPHEN blood pressure effect) can occur with monoamine oxidase inhibitors (MAOI), oxytocin and oxytocic drugs, tricyclic antidepressants, angiotensin and aldosterone, atropine, steroids, norepinephrine transporter inhibitors, ergot alkaloids. (Fenilefrin etiketi, İlaç etkileşimleri)

  • FenitoinantikonvülsanOrta

    Sertraline hydrochloride capsules may increase phenytoin concentrations. (Sertralin etiketi, İlaç etkileşimleri)

  • FenoprofenNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • FenterminMSS uyarıcısıOrta

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, meperidine, methadone, tryptophan, buspirone, amphetamines, and St. (Sertralin etiketi, Uyarılar ve önlemler)

  • Fentermin ve topiramatMSS uyarıcısıOrta

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, meperidine, methadone, tryptophan, buspirone, amphetamines, and St. (Sertralin etiketi, Uyarılar ve önlemler)

  • Fizostigminkolinesteraz inhibitörüOrta

    Acute cardiac arrest may be possible during treatment with tricyclic antidepressants; therefore, Anticholium should only be considered as an antidote for this indication while the patient has continuous ECG monitoring. (Fizostigmin etiketi, Uyarılar ve önlemler)

  • FlurbiprofenNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Flutikazon ve salmeterolkortikosteroidOrta

    Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution. (Flutikazon ve salmeterol etiketi, İlaç etkileşimleri)

  • FondaparinuksantikoagülanOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Formoterolbeta adrenerjik agonistOrta

    • MAO inhibitors, tricyclic antidepressants and drugs that prolong QTc interval may potentiate effect on the cardiovascular system. (Formoterol etiketi, İlaç etkileşimleri)

  • FosamprenavirantiretroviralOrta

    Antidepressant: Paroxetine, trazodone ↓ Paroxetine Any paroxetine dose adjustment should be guided by clinical effect (tolerability and efficacy). ↑ Trazodone Adverse events of nausea, dizziness, hypotension, and syncope have been observed following coadministration of trazodone and ritonavir. (Fosamprenavir etiketi, İlaç etkileşimleri)

  • FosfenitoinantikonvülsanOrta

    Other Corticosteroids, doxycycline, estrogens, furosemide, oral contraceptives, paroxetine, quinidine, rifampin, sertraline, theophylline, and vitamin D Drugs whose level is decreased by phenytoin Anticoagulants Apixaban, dabigatran, edoxaban, rivaroxaban Antiepileptic drugs The effect of phenytoin on phenobarbital, valproic acid and sodium valproate serum levels… (Fosfenitoin etiketi, İlaç etkileşimleri)

  • FosfomisinantibiyotikOrta

    Avoid co-administration of CONTEPO with drugs known to prolong the QT interval, such as class IA or class III antiarrhythmic medications, tricyclic antidepressants, macrolides, and antipsychotics [see Warnings and Precautions ( 5.2 )] . (Fosfomisin etiketi, İlaç etkileşimleri)

  • Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • FoskarnetantiviralOrta

    …prolongation and the potential for torsades de pointes, the use of FOSCAVIR should be avoided in combination with agents known to prolong the QT interval including Class IA (e.g., quinidine or procainamide) or Class III (e.g., dofetilide, amiodarone, sotalol) antiarrhythmic agents, phenothiazines, tricyclic antidepressants, and certain macrolides and fluoroquinolones. (Foskarnet etiketi, İlaç etkileşimleri)

  • Furosemidkıvrım (loop) diüretiğiOrta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • Increase IRESSA to 500 mg daily in patients receiving a strong CYP3A4 inducer (e.g., rifampicin, phenytoin, or tricyclic antidepressant) and resume IRESSA at 250 mg 7 days after discontinuation of the strong inducer [see Dosage and Administration (2.4) , Clinical Pharmacology (12.3) ] . (Gefitinib etiketi, İlaç etkileşimleri)

  • Other Anticholinergic Drugs There is potential for an additive interaction between glycopyrrolate and concomitantly used anticholinergic drugs (e.g., tricyclic antidepressants, anti-epileptics, class I antiarrhythmics, anti­-spasmodics, amantadine) resulting in increased anticholinergic adverse reactions. (Glikopironyum (glikopirolat) etiketi, İlaç etkileşimleri)

  • HeparinantikoagülanOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Hidroklorotiyazidtiyazid diüretikOrta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • İbuprofenNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • İndapamidtiyazid diüretikOrta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • İndometazinNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • İpratropium ve salbutamolantikolinerjikOrta

    Monoamine Oxidase Inhibitors or Tricyclic Antidepressants Ipratropium Bromide and Albuterol Sulfate Inhalation Solution should be administered with extreme caution to patients being treated with monoamine oxidase inhibitors or tricyclic antidepressants, or within 2 weeks of discontinuation of such agents because the action of albuterol sulfate on the cardiovascular… (İpratropium ve salbutamol etiketi, İlaç etkileşimleri)

  • İrbesartan ve hidroklorotiyazidanjiyotensin II reseptör blokeri (ARB)Orta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • İtrakonazolazol antifungalOrta

    SSRIs, Tricyclics and Related Antidepressants Venlafaxine Monitor for adverse reactions. (İtrakonazol etiketi, İlaç etkileşimleri)

  • İzoprenalinbeta adrenerjik agonistOrta

    Drugs that may potentiate clinical response of Isoproterenol Clinical Impact The effects of isoproterenol may be potentiated by tricyclic antidepressants, monoamine oxidase inhibitors, levothyroxine sodium, and certain antihistamines, notably chlorpheniramine, tripelennamine, and diphenhydramine. (İzoprenalin etiketi, İlaç etkileşimleri)

  • Kandesartan ve hidroklorotiyazidanjiyotensin II reseptör blokeri (ARB)Orta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • Kangrelorantitrombosit ilaçOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Karbidopa, levodopa ve entakapondopaminerjik ilaçOrta

    • Tricyclic antidepressants: risk of hypertension and dyskinesia reported during concomitant use with carbidopa/levodopa ( 7.4 ) (Karbidopa, levodopa ve entakapon etiketi, İlaç etkileşimleri)

  • Karisoprodolkas gevşeticiOrta

    Since the sedative effects of carisoprodol and other CNS depressants (e.g., alcohol, benzodiazepines, opioids, tricyclic antidepressants) may be additive, appropriate caution should be exercised with patients who take more than one of these CNS depressants simultaneously. (Karisoprodol etiketi, Uyarılar ve önlemler)

  • KetoprofenNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • KetorolakNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Kinapril ve hidroklorotiyazidACE inhibitörüOrta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • KlonazepambenzodiazepinOrta

    …Interactions The CNS-depressant action of the benzodiazepine class of drugs may be potentiated by alcohol, narcotics, barbiturates, nonbarbiturate hypnotics, antianxiety agents, the phenothiazines, thioxanthene and butyrophenone classes of antipsychotic agents, monoamine oxidase inhibitors and the tricyclic antidepressants, and by other anticonvulsant drugs. (Klonazepam etiketi, İlaç etkileşimleri)

  • Klonidinalfa adrenerjik agonistOrta

    Tricyclic antidepressants Clinical Implication Concomitant use of tricyclic antidepressants with clonidine can increase blood pressure and may counteract the hypotensive effects of clonidine. (Klonidin etiketi, İlaç etkileşimleri)

  • Klopidogrelantitrombosit ilaçOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • KlorazepatbenzodiazepinOrta

    The actions of the benzodiazepines may be potentiated by barbiturates, narcotics, phenothiazines, monoamine oxidase inhibitors or other antidepressants. (Klorazepat etiketi, İlaç etkileşimleri)

  • Kloroprokainlokal anestezikOrta

    Drug Interactions The administration of local anesthetic solutions containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors, tricyclic antidepressants or phenothiazines may produce severe, prolonged hypotension or hypertension. (Kloroprokain etiketi, Önlemler)

  • Klorotiyazidtiyazid diüretikOrta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • Klortalidontiyazid diüretikOrta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • Kokainlokal anestezikOrta

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (Kokain etiketi, İlaç etkileşimleri)

  • Lemboreksantsedatif-hipnotikOrta

    Co-administration with other CNS depressants (e.g., benzodiazepines, opioids, tricyclic antidepressants, alcohol) increases the risk of CNS depression, which can cause daytime impairment. (Lemboreksant etiketi, Uyarılar ve önlemler)

  • Levosalbutamolbeta adrenerjik agonistOrta

    Monoamine oxidase inhibitors (MAOs) or tricyclic antidepressants : May potentiate effect of albuterol on the cardiovascular system. (Levosalbutamol etiketi, İlaç etkileşimleri)

  • Levotiroksintiroid hormonuOrta

    Administration of sertraline in patients stabilized on levothyroxine may result in increased levothyroxine requirements. (Levotiroksin etiketi, İlaç etkileşimleri)

  • Lidokainlokal anestezikOrta

    Clinically Significant Drug Interactions The administration of local anesthetic solutions containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors or tricyclic antidepressants may produce severe, prolonged hypertension. (Lidokain etiketi, İlaç etkileşimleri)

  • Lidokain ve adrenalinlokal anestezikOrta

    …Adverse Reactions Due to Drug Interactions with FLAVALTA Risk of Severe, Persistent Hypertension Due to Drug Interactions Between FLAVALTA and Monoamine Oxidase Inhibitors and Tricyclic Antidepressants Administration of FLAVALTA (containing a vasoconstrictor, epinephrine) in patients receiving monoamine oxidase inhibitors (MAOI), or tricyclic antidepressants may result… (Lidokain ve adrenalin etiketi, Uyarılar ve önlemler)

  • Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • Liyotironintiroid hormonuOrta

    Administration of sertraline in patients stabilized on liothyronine sodium may result in increased liothyronine sodium requirements. (Liyotironin etiketi, İlaç etkileşimleri)

  • Lopinavir ve ritonavirantiretroviralOrta

    Antidepressant: bupropion ↓ bupropion ↓ active metabolite, hydroxybupropion Patients receiving KALETRA and bupropion concurrently should be monitored for an adequate clinical response to bupropion. (Lopinavir ve ritonavir etiketi, İlaç etkileşimleri)

  • Losartan ve hidroklorotiyazidanjiyotensin II reseptör blokeri (ARB)Orta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • LumateperonantipsikotikOrta

    Monitor all antidepressant-treated patients, especially during the initial few months of anti-depressant drug therapy, and at times of dosage changes. (Lumateperon etiketi, Uyarılar ve önlemler)

  • LurasidonantipsikotikOrta

    Activation of Mania/Hypomania Antidepressant treatment can increase the risk of developing a manic or hypomanic episode, particularly in patients with bipolar disorder. (Lurasidon etiketi, Uyarılar ve önlemler)

  • Mefenamik asitNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • MeflokinantimalaryalOrta

    Other Drugs that Prolong the QTc Interval Coadministration of other drugs known to alter cardiac conduction (e.g., anti-arrhythmic or beta-adrenergic blocking agents, calcium channel blockers, antihistamines or H 1 -blocking agents, tricyclic antidepressants and phenothiazines) might also contribute to a prolongation of the QTc interval. (Meflokin etiketi, İlaç etkileşimleri)

  • MeloksikamNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Mepivakainlokal anestezikOrta

    Likewise, solutions of mepivacaine containing a vasoconstrictor, such as epinephrine, should be used with extreme caution in patients receiving monoamine oxidase inhibitors (MAOI) or antidepressants of the triptyline or imipramine types, because severe prolonged hypertension may result. (Mepivakain etiketi, Uyarılar)

  • MetilfenidatMSS uyarıcısıOrta

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, meperidine, methadone, tryptophan, buspirone, amphetamines, and St. (Sertralin etiketi, Uyarılar ve önlemler)

  • Metolazontiyazid diüretikOrta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • MetskopolaminantikolinerjikOrta

    Drug interactions Additive anticholinergic effects may result from concomitant use with antipsychotics, tricyclic antidepressants, and other drugs with anticholinergic effects. (Metskopolamin etiketi, İlaç etkileşimleri)

  • ModafinilMSS uyarıcısıOrta

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, meperidine, methadone, tryptophan, buspirone, amphetamines, and St. (Sertralin etiketi, Uyarılar ve önlemler)

  • NabumetonNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • NalbufinopioidOrta

    Serotonergic Drugs The concomitant use of opioids with other drugs that affect the serotonergic neurotransmitter system, such as selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), triptans, 5-HT3 receptor antagonists, drugs that effect the serotonin neurotransmitter system… (Nalbufin etiketi, İlaç etkileşimleri)

  • Naltrekson ve bupropionopioid antagonistiOrta

    Drugs Metabolized by CYP2D6: Bupropion inhibits CYP2D6 and can increase concentrations of antidepressants, (e.g., selective serotonin reuptake inhibitors and many tricyclics), antipsychotics (e.g., haloperidol, risperidone and thioridazine), beta-blockers (e.g., metoprolol) and Type 1C antiarrhythmics (e.g., propafenone and flecainide). (Naltrekson ve bupropion etiketi, İlaç etkileşimleri)

  • NaproksenNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Antidepressants bupropion ↓ bupropion and active metabolite hydroxy-bupropion Monitor for an adequate clinical response to bupropion. trazodone ↑ trazodone Adverse reactions of nausea, dizziness, hypotension, and syncope have been observed following co-administration of trazodone and ritonavir. (Nirmatrelvir ve ritonavir etiketi, İlaç etkileşimleri)

  • OksaprozinNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Olmesartan ve hidroklorotiyazidanjiyotensin II reseptör blokeri (ARB)Orta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • Olmesartan, amlodipin ve hidroklorotiyazidanjiyotensin II reseptör blokeri (ARB)Orta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • PiroksikamNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Prasugrelantitrombosit ilaçOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Prilokain ve adrenalinlokal anestezikOrta

    …Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine The administration of local anesthetic injections containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors, tricyclic antidepressants or phenothiazines may produce severe, prolonged hypotension or hypertension. (Prilokain ve adrenalin etiketi, İlaç etkileşimleri)

  • PropafenonantiaritmikOrta

    Drugs that inhibit these CYP pathways (such as desipramine, paroxetine, ritonavir, sertraline for CYP2D6; ketoconazole, erythromycin, saquinavir, and grapefruit juice for CYP3A4; and amiodarone and tobacco smoke for CYP1A2) can be expected to cause increased plasma levels of propafenone. (Propafenon etiketi, Uyarılar ve önlemler)

  • RifampisinantibiyotikOrta

    …5-HT 3 Receptor Antagonists Ondansetron Decrease exposure Statins Metabolized by CYP3A4 Simvastatin Decrease exposure Thiazolidinediones Rosiglitazone Decrease AUC by 66% Tricyclic Antidepressants Nortriptyline A tuberculosis treatment regimen including rifampin (600 mg/day), isoniazid (300 mg/day), pyrazinamide (500 mg 3× per day), and pyridoxine (25 mg) was… (Rifampisin etiketi, İlaç etkileşimleri)

  • RifapentinantibiyotikOrta

    …levonorgestrel Immunosuppressants Cyclosporine, tacrolimus Methylxanthines Theophylline Narcotic analgesics Methadone Phosphodiesterase-5 (PDE-5) Inhibitors Sildenafil Thyroid preparations Levothyroxine Tricyclic antidepressants Amitriptyline, nortriptyline 7.5 Other Interactions The conversion of PRIFTIN to 25-desacetyl rifapentine is mediated by an esterase enzyme. (Rifapentin etiketi, İlaç etkileşimleri)

  • RitonavirantiretroviralOrta

    Antidepressants: nefazodone, selective serotonin reuptake inhibitors (SSRIs): e.g. fluoxetine, paroxetine, tricyclics: e.g. amitriptyline, nortriptyline ↑ antidepressants A dose decrease may be needed for these drugs when co-administered with ritonavir. (Ritonavir etiketi, İlaç etkileşimleri)

  • RivaroksabanantikoagülanOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Salbutamolbeta adrenerjik agonistOrta

    Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution. (Salbutamol etiketi, İlaç etkileşimleri)

  • Salmeterolbeta adrenerjik agonistOrta

    • Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution. (Salmeterol etiketi, İlaç etkileşimleri)

  • SalsalatNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • SelekoksibNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Silostazolantitrombosit ilaçOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • SimetidinH2 blokeriOrta

    …apparently through an effect on certain microsomal enzyme systems, has been reported to reduce the hepatic metabolism of warfarin-type anticoagulants, phenytoin, propranolol, nifedipine, chlordiazepoxide, diazepam, certain tricyclic antidepressants, lidocaine, theophylline, and metronidazole, thereby delaying elimination and increasing blood levels of these drugs. (Simetidin etiketi, İlaç etkileşimleri)

  • SinakalsetCYP2D6 inhibitörüOrta

    Dose adjustments may be required for concomitant medications that are predominantly metabolized by CYP2D6 (e.g., desipramine, metoprolol, and carvedilol) and particularly those with a narrow therapeutic index (e.g., flecainide and most tricyclic antidepressants) [see Clinical Pharmacology ( 12.3 )] . (Sinakalset etiketi, İlaç etkileşimleri)

  • SkopolaminantikolinerjikOrta

    Concomitant use of other drugs that cause central nervous system (CNS) adverse reactions (e.g., alcohol, sedatives, hypnotics, opiates, and anxiolytics) or have anticholinergic properties (e.g., other belladonna alkaloids, sedating antihistamines, meclizine, tricyclic antidepressants, and muscle relaxants) may increase this effect [see Drug Interactions ( 7.1 )] . (Skopolamin etiketi, Uyarılar ve önlemler)

  • Sodyum oksibatMSS depresanıOrta

    The concurrent use of Xyrem with other CNS depressants, including but not limited to opioid analgesics, benzodiazepines, sedating antidepressants or antipsychotics, sedating anti-epileptic drugs, general anesthetics, muscle relaxants, and/or illicit CNS depressants, may increase the risk of respiratory depression, hypotension, profound sedation, syncope, and… (Sodyum oksibat etiketi, Uyarılar ve önlemler)

  • Spironolaktonaldosteron antagonistiOrta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • Spironolakton ve hidroklorotiyazidaldosteron antagonistiOrta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • SulindakNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Suvoreksantsedatif-hipnotikOrta

    Co-administration with other CNS depressants (e.g., benzodiazepines, opioids, tricyclic antidepressants, alcohol) increases the risk of CNS depression. (Suvoreksant etiketi, Uyarılar ve önlemler)

  • The efficacy of tricyclic antidepressants can decrease when coadministered with sulfamethoxazole and trimethoprim. (Sülfametoksazol ve trimetoprim etiketi, İlaç etkileşimleri)

  • Telmisartan ve hidroklorotiyazidanjiyotensin II reseptör blokeri (ARB)Orta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • TemazepambenzodiazepinOrta

    The benzodiazepines, including temazepam, produce additive CNS-depressant effects when co-administered with other CNS depressants such as alcohol, barbiturates, antipsychotics, sedative/hypnotics, anxiolytics, antidepressants, narcotic analgesics, sedative antihistamines, anticonvulsants, and anesthetics. (Temazepam etiketi, İlaç etkileşimleri)

  • Terbutalinbeta adrenerjik agonistOrta

    Monoamine Oxidase Inhibitors and Tricyclic Antidepressants Terbutaline sulfate should be administered with extreme caution to patients being treated with monoamine oxidase inhibitors or tricyclic antidepressants, or within 2 weeks of discontinuation of such agents, since the action of terbutaline sulfate on the vascular system may be potentiated. (Terbutalin etiketi, Önlemler)

  • Tikagrelorantitrombosit ilaçOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Tirofibanantitrombosit ilaçOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Tizanidinkas gevşeticiOrta

    The CNS depressant effects of Zanaflex with alcohol and other CNS depressants (e.g., benzodiazepines, opioids, tricyclic antidepressants) may be additive [see Drug Interactions ( 7.4 )] . (Tizanidin etiketi, Uyarılar ve önlemler)

  • TolmetinNSAİİOrta

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (Sertralin etiketi, Uyarılar ve önlemler)

  • Torasemidkıvrım (loop) diüretiğiOrta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • Triamterenpotasyum tutucu diüretikOrta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • Triamteren ve hidroklorotiyazidpotasyum tutucu diüretikOrta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • Umeklidinyum ve vilanterolantikolinerjikOrta

    • Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution. (Umeklidinyum ve vilanterol etiketi, İlaç etkileşimleri)

  • Valsartan ve hidroklorotiyazidanjiyotensin II reseptör blokeri (ARB)Orta

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (Sertralin etiketi, Uyarılar ve önlemler)

  • VarfarinantikoagülanOrta

    For patients taking warfarin, carefully monitor the international normalized ratio. (Sertralin etiketi, Uyarılar ve önlemler)

  • Drugs Suspected of Causing SIADH Use with drugs suspected of causing SIADH (e.g., SSRIs, tricyclic antidepressants, haloperidol, chlorpropamide, enalapril, methyldopa, pentamidine, vincristine, cyclophosphamide, ifosfamide, felbamate) may increase the pressor effect in addition to the antidiuretic effect of Vasostrict ® . (Vazopressin etiketi, İlaç etkileşimleri)

  • Zaleplonsedatif-hipnotikOrta

    Coadministration with other CNS depressants (e.g., benzodiazepines, opioids, tricyclic antidepressants, alcohol) increases the risk of CNS depression. (Zaleplon etiketi, Uyarılar)

  • Zolpidemsedatif-hipnotikOrta

    Sertraline Concomitant administration of zolpidem and sertraline increases exposure to zolpidem [see Clinical Pharmacology (12.3) ] . (Zolpidem etiketi, İlaç etkileşimleri)

Minör değinmeler (31)

  • AbirateronCYP2D6 inhibitörüMinör

    Drugs Metabolized by CYP2D6 Clinical Impact: Sertraline hydrochloride capsules are a CYP2D6 inhibitor [see Clinical Pharmacology ( 12.3 )] . (Sertralin etiketi, İlaç etkileşimleri)

  • AlprazolambenzodiazepinMinör

    False-Positive Effects on Screening Tests for Benzodiazepines False-positive urine immunoassay screening tests for benzodiazepines have been reported in patients taking another sertraline hydrochloride product. (Sertralin etiketi, Uyarılar ve önlemler)

  • AtazanavirantiretroviralMinör

    Antidepressants: tricyclic antidepressants ↑ tricyclic antidepressants Coadministration with REYATAZ has the potential to produce serious and/or life-threatening adverse events and has not been studied. (Atazanavir etiketi, İlaç etkileşimleri)

  • BenztropinantikolinerjikMinör

    Paralytic ileus, hyperthermia and heat stroke, all of which have sometimes been fatal, have occurred in patients taking anticholinergic-type antiparkinsonism drugs, including benztropine mesylate, in combination with phenothiazines and/or tricyclic antidepressants. (Benztropin etiketi, Uyarılar)

  • BrekspiprazolantipsikotikMinör

    However, there is substantial evidence from placebo-controlled maintenance studies in adults with MDD that antidepressants delay the recurrence of depression. (Brekspiprazol etiketi, Uyarılar ve önlemler)

  • DifenhidraminantihistaminikMinör

    Drugs Metabolized by CYP2D6 Clinical Impact: Sertraline hydrochloride capsules are a CYP2D6 inhibitor [see Clinical Pharmacology ( 12.3 )] . (Sertralin etiketi, İlaç etkileşimleri)

  • Divalproeks (valproat)antikonvülsanMinör

    In contrast, drugs that are inhibitors of cytochrome P450 isozymes, e.g., antidepressants, may be expected to have little effect on valproate clearance because cytochrome P450 microsomal mediated oxidation is a relatively minor secondary metabolic pathway compared to glucuronidation and beta-oxidation. (Divalproeks (valproat) etiketi, İlaç etkileşimleri)

  • EluksadolinopioidMinör

    Other Serotonergic Drugs Clinical Impact: Concomitant use of sertraline hydrochloride capsules with other serotonergic drugs (including other SSRIs, SNRIs, triptans, tricyclic antidepressants, opioids, lithium, buspirone, amphetamines, tryptophan, and St. (Sertralin etiketi, İlaç etkileşimleri)

  • EstazolambenzodiazepinMinör

    False-Positive Effects on Screening Tests for Benzodiazepines False-positive urine immunoassay screening tests for benzodiazepines have been reported in patients taking another sertraline hydrochloride product. (Sertralin etiketi, Uyarılar ve önlemler)

  • EverolimusimmünosüpresanMinör

    Drugs Metabolized by CYP2D6 Clinical Impact: Sertraline hydrochloride capsules are a CYP2D6 inhibitor [see Clinical Pharmacology ( 12.3 )] . (Sertralin etiketi, İlaç etkileşimleri)

  • İmatinibCYP3A4 inhibitörüMinör

    Drugs Metabolized by CYP2D6 Clinical Impact: Sertraline hydrochloride capsules are a CYP2D6 inhibitor [see Clinical Pharmacology ( 12.3 )] . (Sertralin etiketi, İlaç etkileşimleri)

  • KarbidopaMinör

    There have been rare reports of adverse reactions, including hypertension and dyskinesia, resulting from the concomitant use of tricyclic antidepressants and carbidopa-levodopa preparations. (Karbidopa etiketi, İlaç etkileşimleri)

  • KariprazinantipsikotikMinör

    …placebo-controlled trials of adult patients with major depressive disorder, the proportion of patients with shifts in fasting glucose from normal (<100 mg/dL) to high (≥126 mg/dL) was greatest in the VRAYLAR 3 mg per day + antidepressant therapy arm (3.2%) compared with those taking VRAYLAR 1.5 mg per day + antidepressant therapy (2%) or those placebo-treated (1.3%). (Kariprazin etiketi, Uyarılar ve önlemler)

  • KlobazambenzodiazepinMinör

    False-Positive Effects on Screening Tests for Benzodiazepines False-positive urine immunoassay screening tests for benzodiazepines have been reported in patients taking another sertraline hydrochloride product. (Sertralin etiketi, Uyarılar ve önlemler)

  • KlordiazepoksitbenzodiazepinMinör

    False-Positive Effects on Screening Tests for Benzodiazepines False-positive urine immunoassay screening tests for benzodiazepines have been reported in patients taking another sertraline hydrochloride product. (Sertralin etiketi, Uyarılar ve önlemler)

  • Klordiazepoksit ve klidinyumbenzodiazepinMinör

    False-Positive Effects on Screening Tests for Benzodiazepines False-positive urine immunoassay screening tests for benzodiazepines have been reported in patients taking another sertraline hydrochloride product. (Sertralin etiketi, Uyarılar ve önlemler)

  • LovastatinstatinMinör

    These include itraconazole, ketoconazole, posaconazole, voriconazole, the macrolide antibiotics erythromycin and clarithromycin, the ketolide antibiotic telithromycin, HIV protease inhibitors, boceprevir, telaprevir, the antidepressant nefazodone, or cobicistat-containing products. (Lovastatin etiketi, Uyarılar)

  • LöprolidMinör

    These included patients with a history of seizures, epilepsy, cerebrovascular disorders, central nervous system anomalies or tumors, and in patients on concomitant medications that have been associated with convulsions such as bupropion and SSRIs. (Löprolid etiketi, Uyarılar ve önlemler)

  • MidazolambenzodiazepinMinör

    False-Positive Effects on Screening Tests for Benzodiazepines False-positive urine immunoassay screening tests for benzodiazepines have been reported in patients taking another sertraline hydrochloride product. (Sertralin etiketi, Uyarılar ve önlemler)

  • Mirabegronbeta adrenerjik agonistMinör

    Drugs Metabolized by CYP2D6 Clinical Impact: Sertraline hydrochloride capsules are a CYP2D6 inhibitor [see Clinical Pharmacology ( 12.3 )] . (Sertralin etiketi, İlaç etkileşimleri)

  • OksazepambenzodiazepinMinör

    False-Positive Effects on Screening Tests for Benzodiazepines False-positive urine immunoassay screening tests for benzodiazepines have been reported in patients taking another sertraline hydrochloride product. (Sertralin etiketi, Uyarılar ve önlemler)

  • Other Serotonergic Drugs Clinical Impact: Concomitant use of sertraline hydrochloride capsules with other serotonergic drugs (including other SSRIs, SNRIs, triptans, tricyclic antidepressants, opioids, lithium, buspirone, amphetamines, tryptophan, and St. (Sertralin etiketi, İlaç etkileşimleri)

  • PerfenazinantipsikotikMinör

    Drug Interactions Metabolism of a number of medications, including antipsychotics, antidepressants, β-blockers, and antiarrhythmics, occurs through the cytochrome P450 2D6 isoenzyme (debrisoquine hydroxylase). (Perfenazin etiketi, İlaç etkileşimleri)

  • Propranololbeta blokerMinör

    Antidepressants: The hypotensive effect of MAO inhibitors or tricyclic antidepressants may be exacerbated when administered with beta-blockers. (Propranolol etiketi, İlaç etkileşimleri)

  • RolapitantCYP2D6 inhibitörüMinör

    Drugs Metabolized by CYP2D6 Clinical Impact: Sertraline hydrochloride capsules are a CYP2D6 inhibitor [see Clinical Pharmacology ( 12.3 )] . (Sertralin etiketi, İlaç etkileşimleri)

  • TerbinafinantifungalMinör

    Drugs Metabolized by CYP2D6 Clinical Impact: Sertraline hydrochloride capsules are a CYP2D6 inhibitor [see Clinical Pharmacology ( 12.3 )] . (Sertralin etiketi, İlaç etkileşimleri)

  • TiagabinantikonvülsanMinör

    In most cases, patients were using concomitant medications (antidepressants, antipsychotics, stimulants, narcotics) that are thought to lower the seizure threshold. (Tiagabin etiketi, Uyarılar)

  • TolkaponMinör

    It is difficult to determine if Tolcapone tablets played a role in the pathogenesis of these events because these patients received several concomitant medications affecting the central nervous system such as monoaminergic (i.e., MAO-I, tricyclic and selective serotonin reuptake inhibitors) and anticholinergic agents. (Tolkapon etiketi, Önlemler)

  • TriazolambenzodiazepinMinör

    False-Positive Effects on Screening Tests for Benzodiazepines False-positive urine immunoassay screening tests for benzodiazepines have been reported in patients taking another sertraline hydrochloride product. (Sertralin etiketi, Uyarılar ve önlemler)

  • TriheksifenidilantikolinerjikMinör

    Monoamine oxidase inhibitors and tricyclic antidepressants possessing significant anticholinergic activity may intensify the anticholinergic effects of antidyskinetic agents because of the secondary anticholinergic activities of these medications. (Triheksifenidil etiketi, İlaç etkileşimleri)

  • Valproik asitantikonvülsanMinör

    In contrast, drugs that are inhibitors of cytochrome P450 isozymes, e.g., antidepressants, may be expected to have little effect on valproate clearance because cytochrome P450 microsomal mediated oxidation is a relatively minor secondary metabolic pathway compared to glucuronidation and beta-oxidation. (Valproik asit etiketi, İlaç etkileşimleri)

Anlamlı etkileşim olmadığı bildirilenler (7)

  • AripiprazolantipsikotikEtkileşim yok

    Additionally, no dosage adjustment is necessary for valproate, lithium, lamotrigine, lorazepam, or sertraline when coadministered with ABILIFY MAINTENA. [See Clinical Pharmacology (12.3) ] . (Aripiprazol etiketi, İlaç etkileşimleri)

  • Atenololbeta blokerEtkileşim yok

    Additionally, no dosage adjustment is required for diazepam, lithium, atenolol, tolbutamide, digoxin, and drugs metabolized by CYP3A4, when sertraline hydrochloride capsules is administered concomitantly [see Clinical Pharmacology ( 12.3 )] . (Sertralin etiketi, İlaç etkileşimleri)

  • DesloratadinantihistaminikEtkileşim yok

    …changes in the safety profile of desloratadine. [See Clinical Pharmacology (12.3) .] 7.2 Fluoxetine In controlled clinical studies co-administration of desloratadine with fluoxetine, a selective serotonin reuptake inhibitor (SSRI), resulted in increased plasma concentrations of desloratadine and 3 hydroxydesloratadine, but there were no clinically relevant changes… (Desloratadin etiketi, İlaç etkileşimleri)

  • Digoksindijital glikozidiEtkileşim yok

    Additionally, no dosage adjustment is required for diazepam, lithium, atenolol, tolbutamide, digoxin, and drugs metabolized by CYP3A4, when sertraline hydrochloride capsules is administered concomitantly [see Clinical Pharmacology ( 12.3 )] . (Sertralin etiketi, İlaç etkileşimleri)

  • Emtrisitabin ve tenofovirantiretroviralEtkileşim yok

    No clinically significant drug interactions have been either observed or are expected when DESCOVY is combined with the following drugs: buprenorphine, itraconazole, ketoconazole, lorazepam, methadone, midazolam, naloxone, norbuprenorphine, norgestimate/ethinyl estradiol, and sertraline. (Emtrisitabin ve tenofovir etiketi, İlaç etkileşimleri)

  • EntakaponEtkileşim yok

    No interaction with the tricyclic antidepressant imipramine was shown in a single-dose study with entacapone without coadministered levodopa and dopa-decarboxylase inhibitor. (Entakapon etiketi, Önlemler)

  • Ropiniroldopamin agonistiEtkileşim yok

    Commonly Administered Drugs: Population analysis showed that commonly administered drugs (e.g., selegiline, amantadine, tricyclic antidepressants, benzodiazepines, ibuprofen, thiazides, antihistamines, anticholinergics) did not affect the clearance of ropinirole. (Ropinirol etiketi, İlaç etkileşimleri)

Kullandığınız her şeyi Sertralin ile karşılaştırın. Tüm listenizi ekleyin; her çift tek seferde kontrol edilir.

Sorgulama aracında aç

Tıbbi tavsiye değildir. Şiddet derecesi sizin koşullarınızı değil, etiketin ifadesini yansıtır. “Majör” işareti gözetim altında olağan bir uygulama olabilir, “minör” işareti ise yüksek dozlarda önem kazanabilir. Bir eczacıya danışın.