التداخل بين الجريب فروت وفيراباميل

Grapefruit juice may significantly increase verapamil levels ( 7.3 )

Grapefruit Juice Grapefruit juice may significantly increase concentrations of verapamil.

Grapefruit juice given to nine healthy volunteers increased S- and R- verapamil AUC 0-12 by 36% and 28%, respectively.

Steady state C max and C min of S-verapamil increased by 57% and 16.7%, respectively with grapefruit juice compared to control.

Grapefruit juice did not cause a significant difference in the pharmacokinetics of norverapamil.