تداخلات التبغ والتدخين
الدخان (لا النيكوتين نفسه) يحرّض إنزيم CYP1A2، فيخفض مستويات بعض الأدوية في الدم؛ والإقلاع عن التدخين قد يرفع تلك المستويات بعد ذلك.
التبغ والتدخين: 100 تداخل موثّق في نشرات FDA وصحائف الوقائع التي نفهرسها، وتوزيعها: شديدة 20، متوسطة 71، طفيفة 9، وحالات تفيد فيها نشرة بعدم وجود تداخل مهم 0. كل مُدخل أدناه يقتبس الجملة التي يستند إليها. هذه الصفحة (التبغ والقنّب) نقطة انطلاق، وليست حكمًا على حالتك.
تداخلات من النشرة
تداخلات شديدة (20)
Patients who are current or past smokers are at additional increased risk [see Warnings and Precautions (5.3) ] . (نشرة أبروسيتينيب، تحذير مؤطر)
- إرلوتينيبشديد
Avoid smoking tobacco (CYP1A2 inducer) and avoid concomitant use of erlotinib with moderate CYP1A2 inducers (e.g., teriflunomide, rifampin, or phenytoin). (نشرة إرلوتينيب، التداخلات الدوائية)
WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptives (COC) use. (نشرة إستراديول ودينوجيست، تحذير مؤطر)
Patients who are current or past smokers are at additional increased risk [see Warnings and Precautions ( 5.3 )] . (نشرة أوباداسيتينيب، تحذير مؤطر)
WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS Cigarette smoking increases the risk of serious cardiovascular events from combination hormonal contraceptive (CHC) use. (نشرة إيتونوجيستريل وإيثينيل إستراديول، تحذير مؤطر)
Cigarette smoking increases the risk of serious adverse effects on the heart and blood vessels from oral contraceptive use. (نشرة إيثينوديول ثنائي الأسيتات وإيثينيل إستراديول، تحذير مؤطر)
Instruct the patient to avoid heat, flame, and/or smoking during and immediately following application. (نشرة إيكونازول، التحذيرات والاحتياطات)
Patients who are current or past smokers are at additional increased risk [see Warnings and Precautions ( 5.3 )]. (نشرة باريسيتينيب، تحذير مؤطر)
Patients who are current or past smokers are at additional increased risk. (نشرة توفاسيتينيب، تحذير مؤطر)
WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptives (COC) use. (نشرة دروسبيرينون وإيثينيل إستراديول، تحذير مؤطر)
WARNING: CARDIOVASCULAR RISK ASSOCIATED WITH SMOKING Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptive use. (نشرة ديسوجيستريل وإيثينيل إستراديول، تحذير مؤطر)
- فارينيكلينشديد
In a smoking cessation trial in patients with stable CV disease, CV events were infrequent overall; however, nonfatal myocardial infarction (MI) and nonfatal stroke occurred more frequently in patients treated with CHANTIX compared to placebo. (نشرة فارينيكلين، التحذيرات والاحتياطات)
Therefore, patients being treated with phenelzine sulfate should avoid high protein food that has undergone protein breakdown by aging, fermentation, pickling, smoking, or bacterial contamination. (نشرة فينيلزين، موانع الاستعمال)
Instruct the patient the avoid fire, flame, and smoking during and immediately following application. (نشرة كالسيبوتريول، التحذيرات والاحتياطات)
WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS Cigarette smoking increases the risk of serious cardiovascular events from combined hormonal contraceptive (CHC) use. (نشرة ليفونورجيستريل وإيثينيل إستراديول، تحذير مؤطر)
WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptive (COC) use. (نشرة نورجيستريل وإيثينيل إستراديول، تحذير مؤطر)
WARNING: CIGARETTE SMOKING and SERIOUS CARDIOVASCULAR EVENTS WARNING: CIGARETTE SMOKING and SERIOUS CARDIOVASCULAR EVENTS See full prescribing information for complete boxed warning. ● Mono-Linyah is contraindicated in women over 35 years old who smoke. (نشرة نورجيستيمات وإيثينيل إستراديول، تحذير مؤطر)
WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptive (COC ) use. (نشرة نوريثيستيرون وإيثينيل إستراديول، تحذير مؤطر)
WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS and CONTRAINDICATED IN WOMEN WITH A BMI |GTE 30 kg/m2 • Cigarette Smoking and Serious Cardiovascular Events Cigarette smoking increases the risk of serious cardiovascular events from hormonal contraceptive use. (نشرة نوريلجيسترومين وإيثينيل إستراديول، تحذير مؤطر)
Patients with congenital (Leber's) optic atrophy or with tobacco amblyopia have unusually high cyanide/thiocyanate ratios. (نشرة نيتروبروسيد، موانع الاستعمال)
تداخلات متوسطة (71)
When receiving intravenous ORENCIA, patients that require blood glucose monitoring should be advised to consider methods that do not react with maltose, such as those based on glucose dehydrogenase nicotine adenine dinucleotide (GDH-NAD), glucose oxidase, or glucose hexokinase test methods. (نشرة أباتاسبت، التداخلات الدوائية)
As a precaution, the underlying risk of coronary heart disease should be considered when prescribing antiretroviral therapies, including abacavir, and action taken to minimize all modifiable risk factors (e.g., hypertension, hyperlipidemia, diabetes mellitus, smoking). (نشرة أباكافير، التحذيرات والاحتياطات)
As a precaution, the underlying risk of coronary heart disease should be considered when prescribing antiretroviral therapies, including abacavir, and action taken to minimize all modifiable risk factors (e.g., hypertension, hyperlipidemia, diabetes mellitus, smoking). (نشرة أباكافير ولاميفودين، التحذيرات والاحتياطات)
In controlled trials of other TNF blockers in adult patients at higher risk for malignancies (i.e., patients with COPD with a significant smoking history and cyclophosphamide-treated patients with Wegener’s granulomatosis), a greater portion of malignancies occurred in the TNF blocker group compared to the control group. (نشرة أداليموماب، التحذيرات والاحتياطات)
Smokers have an increased clearance of benzodiazepines as compared to nonsmokers; this was seen in studies with estazolam (see CLINICAL PHARMACOLOGY ). (نشرة إستازولام، التداخلات الدوائية)
Risk factors for arterial vascular disease (e.g., hypertension, diabetes mellitus, tobacco use, hypercholesterolemia, and obesity) and/or venous thromboembolism (e.g., personal history or family history of VTE, obesity, and systemic lupus erythematosus) should be managed appropriately. a. (نشرة إستراديول، التحذيرات)
Manage appropriately any risk factors for arterial vascular disease (for example, hypertension, diabetes mellitus, tobacco use, hypercholesterolemia, and obesity) and/or venous thromboembolism (VTE) (for example, personal history or family history of VTE, obesity, and systemic lupus erythematosus). (نشرة إستراديول ونوريثيستيرون، التحذيرات والاحتياطات)
Risk factors for arterial vascular disease (e.g., hypertension, diabetes mellitus, tobacco use, hypercholesterolemia, and obesity) and/or venous thromboembolism (e.g., personal history or family history of VTE, obesity, and systemic lupus erythematosus) should be managed appropriately. (نشرة إستروجينات مؤسترة وميثيل تستوستيرون، التحذيرات)
Risk factors for arterial vascular disease (for example, hypertension, diabetes mellitus, tobacco use, hypercholesterolemia, and obesity) and/or venous thromboembolism (VTE) (for example, personal history or family history of VTE, obesity, and systemic lupus erythematosus) should be managed appropriately. a. (نشرة إستروجينات مقترنة، التحذيرات)
Risk factors for arterial vascular disease (for example, hypertension, diabetes mellitus, tobacco use, hypercholesterolemia, and obesity) and/or VTE (for example, personal history or family history of VTE, obesity, and systemic lupus erythematosus) should be managed appropriately. (نشرة إستروجينات مقترنة وبازيدوكسيفين، التحذيرات والاحتياطات)
Perform a cardiovascular evaluation in triptan-naïve patients who have multiple cardiovascular risk factors (e.g., increased age, diabetes, hypertension, smoking, obesity, strong family history of CAD) prior to receiving RELPAX. (نشرة إليتريبتان، التحذيرات والاحتياطات)
…elevations for longer periods Hypothyroidism Liver disease; cirrhosis, acute hepatitis Reduced renal function in infants <3 months of age Sepsis with multi-organ failure Shock Cessation of Smoking Drug Interactions Adding a drug that inhibits theophylline metabolism (e.g., cimetidine, erythromycin, tacrine) or stopping a concurrently administered drug that enhances theophylline… (نشرة أمينوفيلين، التحذيرات)
Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (نشرة إندوميثاسين، التحذيرات والاحتياطات)
In both cases, a prior history of heavy tobacco use was identified as a risk factor for lung cancer. (نشرة إنسولين عادي (بشري)، التحذيرات والاحتياطات)
Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, antiplatelet drugs (such as aspirin), anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (نشرة أوكسابروزين، التحذيرات والاحتياطات)
This results in a mean increase in olanzapine Cmax following fluvoxamine of 54% in female nonsmokers and 77% in male smokers. (نشرة أولانزابين، التداخلات الدوائية)
This results in a mean increase in olanzapine C max following fluvoxamine administration of 54% in female nonsmokers and 77% in male smokers. (نشرة أولانزابين وفلوكسيتين، التداخلات الدوائية)
- أوماليزومابمتوسط
The impact of longer exposure to omalizumab products or use in patients at higher risk for malignancy (e.g., elderly, current smokers) is not known. (نشرة أوماليزوماب، التحذيرات والاحتياطات)
Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (نشرة إيبوبروفين، التحذيرات والاحتياطات)
Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (نشرة إيبوبروفين وفاموتيدين، التحذيرات والاحتياطات)
Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (نشرة إيتودولاك، التحذيرات)
Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy, concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (نشرة باراسيتامول وإيبوبروفين، التحذيرات والاحتياطات)
Drugs that inhibit these CYP pathways (such as desipramine, paroxetine, ritonavir, sertraline for CYP2D6; ketoconazole, erythromycin, saquinavir, and grapefruit juice for CYP3A4; and amiodarone and tobacco smoke for CYP1A2) can be expected to cause increased plasma levels of propafenone. (نشرة بروبافينون، التحذيرات والاحتياطات)
CYP1A2 and CYP2C19 Inducers: CYP1A2 inducers (e.g., phenytoin, montelukast, smoking) and CYP2C19 inducers (e.g. rifampin) decrease the plasma levels of propranolol resulting in a loss of efficacy [see Clinical Pharmacology ( 12.7 )] . (نشرة بروبرانولول، التداخلات الدوائية)
Tobacco Smoking tobacco could enhance the metabolic clearance rate of pentazocine reducing the clinical effectiveness of a standard dose of pentazocine. (نشرة بنتازوسين ونالوكسون، التداخلات الدوائية)
Monitoring of blood pressure is recommended in patients who receive the combination of bupropion and nicotine replacement. (نشرة بوبروبيون، التحذيرات والاحتياطات)
Patients with major risk factors for decreased bone mineral content, such as prolonged immobilization, family history of osteoporosis, post menopausal status, tobacco use, advance age, poor nutrition, or chronic use of drugs that can reduce bone mass (e.g., anticonvulsants, oral corticosteroids) should be monitored and treated with established standards of care. (نشرة بوديزونيد، التحذيرات والاحتياطات)
Patients with major risk factors for decreased bone mineral content, such as prolonged immobilization, family history of osteoporosis, postmenopausal status, tobacco use, advanced age, poor nutrition, or chronic use of drugs that can reduce bone mass (e.g., anticonvulsants, oral corticosteroids) should be monitored and treated with established standards of care. (نشرة بوديزونيد وفورموتيرول، التحذيرات والاحتياطات)
- بوماليدوميدمتوسط
Patients with known risk factors, including prior thrombosis, may be at greater risk, and actions should be taken to try to minimize all modifiable factors (e.g., hyperlipidemia, hypertension, smoking). (نشرة بوماليدوميد، التحذيرات والاحتياطات)
Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, antiplatelet drugs (such as aspirin), anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (نشرة بيروكسيكام، التحذيرات والاحتياطات)
Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (نشرة تولميتين، التحذيرات)
Cessation of Smoking: Drug Interactions: Adding a drug that inhibits theophylline metabolism (e.g., cimetidine, erythromycin, tacrine) or stopping a concurrently administered drug that enhances theophylline metabolism (e.g., carbamazepine, rifampin). (نشرة ثيوفيلين، التحذيرات)
Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy, concomitant use of oral corticosteroids, anti-platelet drugs (such as aspirin), anticoagulants, or selective serotonin reuptake inhibitors (SSRIs), smoking, use of alcohol, older age, and poor general health status. (نشرة حمض الميفيناميك، التحذيرات والاحتياطات)
Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (نشرة ديفلونيزال، التحذيرات)
Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (نشرة ديكلوفيناك، التحذيرات والاحتياطات)
Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, antiplatelet drugs (such as aspirin), anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (نشرة ديكلوفيناك وميزوبروستول، التحذيرات والاحتياطات)
The risk-benefit balance should be considered in women at risk for stroke, such as prior stroke or transient ischemic attack (TIA), atrial fibrillation, hypertension, or cigarette smoking [see Clinical Studies ( 14.5 )] . (نشرة رالوكسيفين، التحذيرات والاحتياطات)
Cigarette smoking is expected to increase the clearance of ropinirole since CYP1A2 is known to be induced by smoking hormone replacement therapy [ see Clinical Pharmacology ( 12.3 ) ]. (نشرة روبينيرول، التداخلات الدوائية)
Secondary Malignancies: Monitor for development of secondary malignancies, particularly in patients who are current or past smokers. (نشرة روكسوليتينيب، التحذيرات والاحتياطات)
In this study, current or past smokers had an additional increased risk of overall malignancies. (نشرة ريتليسيتينيب، التحذيرات والاحتياطات)
Triptan-naïve patients who have multiple cardiovascular risk factors (e.g., increased age, diabetes, hypertension, smoking, obesity, strong family history of CAD) should have a cardiovascular evaluation prior to receiving MAXALT. (نشرة ريزاتريبتان، التحذيرات والاحتياطات)
Pharmacokinetic Interactions with Adempas Smoking: Plasma concentrations in smokers are reduced by 50% to 60% compared to nonsmokers. (نشرة ريوسيغوات، التداخلات الدوائية)
Perform a cardiovascular evaluation in triptan-naïve patients who have multiple cardiovascular risk factors (e.g., increased age, diabetes, hypertension, smoking, obesity, strong family history of CAD) prior to receiving zolmitriptan. (نشرة زولميتريبتان، التحذيرات والاحتياطات)
Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (نشرة سالسالات، التحذيرات)
Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (نشرة سولينداك، التحذيرات)
Perform a cardiovascular evaluation in triptan-naive patients who have multiple cardiovascular risk factors (e.g., increased age, diabetes, hypertension, smoking, obesity, strong family history of CAD) prior to receiving IMITREX tablets. (نشرة سوماتريبتان، التحذيرات والاحتياطات)
Perform a cardiovascular evaluation in patients who have multiple cardiovascular risk factors (e.g., increased age, diabetes, hypertension, smoking, obesity, strong family history of CAD) prior to receiving sumatriptan and naproxen sodium tablets. (نشرة سوماتريبتان ونابروكسين، التحذيرات والاحتياطات)
Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, antiplatelet drugs (such as aspirin), anticoagulants; or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (نشرة سيليكوكسيب، التحذيرات والاحتياطات)
Perform a cardiovascular evaluation in triptan-naïve patients who have multiple cardiovascular risk factors (e.g., increased age, diabetes, hypertension, smoking, obesity, strong family history of CAD) prior to receiving frovatriptan succinate. (نشرة فروفاتريبتان، التحذيرات والاحتياطات)
In patients susceptible to aniline toxicity (e.g. persons with glucose-6-phosphate dehydrogenase deficiency, hemoglobin M disease and smokers), monitoring of methemoglobin levels should be considered. (نشرة فلوتاميد، التحذيرات)
Patients with major risk factors for decreased bone mineral content, such as prolonged immobilization, family history of osteoporosis, postmenopausal status, tobacco use, advanced age, poor nutrition, or chronic use of drugs that can reduce bone mass (e.g., anticonvulsants, oral corticosteroids), should be monitored and treated with established standards of care. (نشرة فلوتيكازون، التحذيرات والاحتياطات)
Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking, use of alcohol, older age, and poor general health status. (نشرة فلوربيبروفين، التحذيرات والاحتياطات)
Theophylline: The effect of steady-state fluvoxamine (50 mg bid) on the pharmacokinetics of a single dose of theophylline (375 mg as 442 mg aminophylline) was evaluated in 12 healthy non-smoking, male volunteers. (نشرة فلوفوكسامين، التحذيرات والاحتياطات)
Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (نشرة فينوبروفين، التحذيرات والاحتياطات)
In addition, the majority of more recent case-control and cohort studies of benzodiazepine use during pregnancy, which were adjusted for confounding exposures to alcohol, tobacco and other medications, have not confirmed these findings. (نشرة كلورازيبات، التداخلات الدوائية)
In addition, the majority of more recent case-control and cohort studies of benzodiazepine use during pregnancy, which were adjusted for confounding exposures to alcohol, tobacco and other medications, have not confirmed these findings. (نشرة كلورديازيبوكسيد، التداخلات الدوائية)
• Discontinuation of CYP1A2 or CYP3A4 Inducers: Consider reducing CLOZARIL dose when CYP1A2 inducers (e.g., tobacco smoke) or CYP3A4 inducers (e.g., carbamazepine) are discontinued. (نشرة كلوزابين، التداخلات الدوائية)
Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (نشرة كيتوبروفين، التحذيرات)
In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (نشرة كيتورولاك، التحذيرات والاحتياطات)
Cigarette Smoking (CYP1A2 Inducer) In healthy male heavy smokers, the mean quinine AUC following a single 600 mg dose was 44% lower, the mean C max was 18% lower, and the elimination half-life was shorter (7.5 hours versus 12 hours) than in their non-smoking counterparts. (نشرة كينين، التداخلات الدوائية)
- ليناليدوميدمتوسط
Patients with known risk factors, including prior thrombosis, may be at greater risk and actions should be taken to try to minimize all modifiable factors (e.g. hyperlipidemia, hypertension, smoking). (نشرة ليناليدوميد، التحذيرات والاحتياطات)
Coronary artery disease Patients with coronary artery disease or risk factors for coronary artery disease (e.g., smoking, obesity, diabetes, high cholesterol) may be more susceptible to developing myocardial ischemia and infarction associated with methylergonovine-induced vasospasm. (نشرة ميثيل إرغونوفين، التحذيرات)
MPA Injectable Suspension, USP can pose an additional risk in patients with risk factors for osteoporosis (e.g., metabolic bone disease, chronic alcohol and/or tobacco use, anorexia nervosa, strong family history of osteoporosis or chronic use of drugs that can reduce bone mass such as anticonvulsants or corticosteroids). (نشرة ميدروكسي بروجستيرون، التحذيرات والاحتياطات)
Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (نشرة ميلوكسيكام، التحذيرات والاحتياطات)
Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (نشرة نابروكسين، التحذيرات والاحتياطات)
Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (نشرة نابروكسين وإيزوميبرازول، التحذيرات والاحتياطات)
Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (نشرة نابوميتون، التحذيرات)
Perform a cardiovascular evaluation in triptan-naive patients who have multiple cardiovascular risk factors (e.g., increased age, diabetes, hypertension, smoking, obesity, strong family history of CAD) prior to receiving naratriptan tablets. (نشرة ناراتريبتان، التحذيرات والاحتياطات)
WARNINGS Cigarette smoking increases the risk of serious cardiovascular disease. (نشرة نوريثيستيرون، التحذيرات)
Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (نشرة هيدروكودون وإيبوبروفين، التحذيرات)
…contraceptives, phenylpropanolamine, propafenone, propranolol, terbinafine, thiabendazole, ticlopidine, verapamil, zileuton montelukast, moricizine, omeprazole, phenobarbital, phenytoin, cigarette smoking CYP3A4 alprazolam, amiodarone, amlodipine, amprenavir, aprepitant, atorvastatin, atazanavir, bicalutamide, cilostazol, cimetidine, ciprofloxacin, clarithromycin, conivaptan,… (نشرة وارفارين، التداخلات الدوائية)
إشارات طفيفة (9)
Nicotine may provoke vasoconstriction in some patients, predisposing to a greater ischemic response to ergot therapy. (نشرة إرغوتامين وكافيين، التداخلات الدوائية)
All patients had a history of heavy smoking [see Adverse Reactions (6.1) ] . (نشرة إنفليكسيماب، التحذيرات والاحتياطات)
This is of particular concern in women who are obese or smoke cigarettes, especially smokers over 35 years of age. (نشرة حمض الترانيكساميك، التحذيرات والاحتياطات)
Ask a doctor before use if you have chronic cough that lasts such as occurs with smoking, asthma, or emphysema cough that occurs with too much phlegm (mucus) Stop use and ask a doctor if cough lasts more than 7 days, comes back, or occurs with fever, rash, or headache that lasts. (نشرة ديكستروميثورفان، التحذيرات)
Nicotine Nicotine may provoke vasoconstriction in some patients, predisposing to a greater ischemic response to ergot therapy. (نشرة ديهيدروإرغوتامين، التداخلات الدوائية)
Tobacco and other medications, have not confirmed these findings. (نشرة كلورديازيبوكسيد وكليدينيوم، التداخلات الدوائية)
Quinidine's pharmacokinetics are also unaffected by cigarette smoking. (نشرة كينيدين، التداخلات الدوائية)
Some patients who stopped smoking may have been experiencing symptoms of nicotine withdrawal, including depressed mood. (نشرة نالتريكسون وبوبروبيون، التحذيرات والاحتياطات)
Other Interactions Digitalis, tetracyclines, nicotine, or antihistamines, or intravenous nitroglycerin may partially counteract the anticoagulant action of heparin sodium. (نشرة هيبارين، التداخلات الدوائية)
افحص التبغ والتدخين مع كل ما تتناوله. أضف قائمتك كاملة؛ تُفحص كل الأزواج دفعة واحدة.
افتح في الفاحصليست نصيحة طبية. درجة الشدة تعكس صياغة النشرة، لا ظروفك. فالتنبيه «الشديد» قد يكون أمرًا معتادًا تحت الإشراف، والتنبيه «الطفيف» قد يكون مهمًا عند الجرعات العالية. اسأل صيدليًا.