Interaksi Tembakau dan merokok

Asap rokok (bukan nikotin itu sendiri) menginduksi enzim CYP1A2 sehingga menurunkan kadar beberapa obat dalam darah; berhenti merokok kemudian dapat menaikkan kadar tersebut.

Tembakau dan merokok memiliki 100 interaksi terdokumentasi dalam label FDA dan lembar fakta yang kami indeks: 20 mayor, 71 moderat, 9 minor, dan 0 dengan label yang melaporkan tidak ada interaksi bermakna. Setiap entri di bawah ini mengutip kalimat yang mendasarinya. Halaman dalam kelompok Tembakau dan ganja ini adalah titik awal, bukan putusan untuk situasi Anda.

Interaksi dari label

Interaksi mayor (20)

  • Abrositinibpenghambat JAKMayor

    Patients who are current or past smokers are at additional increased risk [see Warnings and Precautions (5.3) ] . (label Abrositinib, Peringatan kotak hitam)

  • Barisitinibpenghambat JAKMayor

    Patients who are current or past smokers are at additional increased risk [see Warnings and Precautions ( 5.3 )]. (label Barisitinib, Peringatan kotak hitam)

  • Desogestrel dan etinilestradiolkontrasepsi oralMayor

    WARNING: CARDIOVASCULAR RISK ASSOCIATED WITH SMOKING Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptive use. (label Desogestrel dan etinilestradiol, Peringatan kotak hitam)

  • Drospirenon dan etinilestradiolkontrasepsi oralMayor

    WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptives (COC) use. (label Drospirenon dan etinilestradiol, Peringatan kotak hitam)

  • Ekonazolantijamur azolMayor

    Instruct the patient to avoid heat, flame, and/or smoking during and immediately following application. (label Ekonazol, Peringatan dan perhatian)

  • Avoid smoking tobacco (CYP1A2 inducer) and avoid concomitant use of erlotinib with moderate CYP1A2 inducers (e.g., teriflunomide, rifampin, or phenytoin). (label Erlotinib, Interaksi obat)

  • Estradiol dan dienogestkontrasepsi oralMayor

    WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptives (COC) use. (label Estradiol dan dienogest, Peringatan kotak hitam)

  • Cigarette smoking increases the risk of serious adverse effects on the heart and blood vessels from oral contraceptive use. (label Etinodiol diasetat dan etinilestradiol, Peringatan kotak hitam)

  • WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS Cigarette smoking increases the risk of serious cardiovascular events from combination hormonal contraceptive (CHC) use. (label Etonogestrel dan etinilestradiol, Peringatan kotak hitam)

  • Fenelzinpenghambat MAOMayor

    Therefore, patients being treated with phenelzine sulfate should avoid high protein food that has undergone protein breakdown by aging, fermentation, pickling, smoking, or bacterial contamination. (label Fenelzin, Kontraindikasi)

  • Kalsipotriolanalog vitamin DMayor

    Instruct the patient the avoid fire, flame, and smoking during and immediately following application. (label Kalsipotriol, Peringatan dan perhatian)

  • WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS Cigarette smoking increases the risk of serious cardiovascular events from combined hormonal contraceptive (CHC) use. (label Levonorgestrel dan etinilestradiol, Peringatan kotak hitam)

  • NitroprusidvasodilatorMayor

    Patients with congenital (Leber's) optic atrophy or with tobacco amblyopia have unusually high cyanide/thiocyanate ratios. (label Nitroprusid, Kontraindikasi)

  • WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS and CONTRAINDICATED IN WOMEN WITH A BMI |GTE 30 kg/m2 • Cigarette Smoking and Serious Cardiovascular Events Cigarette smoking increases the risk of serious cardiovascular events from hormonal contraceptive use. (label Norelgestromin dan etinilestradiol, Peringatan kotak hitam)

  • WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptive (COC ) use. (label Noretisteron dan etinilestradiol, Peringatan kotak hitam)

  • Norgestimat dan etinilestradiolkontrasepsi oralMayor

    WARNING: CIGARETTE SMOKING and SERIOUS CARDIOVASCULAR EVENTS WARNING: CIGARETTE SMOKING and SERIOUS CARDIOVASCULAR EVENTS See full prescribing information for complete boxed warning. ● Mono-Linyah is contraindicated in women over 35 years old who smoke. (label Norgestimat dan etinilestradiol, Peringatan kotak hitam)

  • Norgestrel dan etinilestradiolkontrasepsi oralMayor

    WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptive (COC) use. (label Norgestrel dan etinilestradiol, Peringatan kotak hitam)

  • TofasitinibimunosupresanMayor

    Patients who are current or past smokers are at additional increased risk. (label Tofasitinib, Peringatan kotak hitam)

  • UpadasitinibimunosupresanMayor

    Patients who are current or past smokers are at additional increased risk [see Warnings and Precautions ( 5.3 )] . (label Upadasitinib, Peringatan kotak hitam)

  • In a smoking cessation trial in patients with stable CV disease, CV events were infrequent overall; however, nonfatal myocardial infarction (MI) and nonfatal stroke occurred more frequently in patients treated with CHANTIX compared to placebo. (label Vareniklin, Peringatan dan perhatian)

Interaksi moderat (71)

  • AbakavirantiretroviralModerat

    As a precaution, the underlying risk of coronary heart disease should be considered when prescribing antiretroviral therapies, including abacavir, and action taken to minimize all modifiable risk factors (e.g., hypertension, hyperlipidemia, diabetes mellitus, smoking). (label Abakavir, Peringatan dan perhatian)

  • Abakavir dan lamivudinantiretroviralModerat

    As a precaution, the underlying risk of coronary heart disease should be considered when prescribing antiretroviral therapies, including abacavir, and action taken to minimize all modifiable risk factors (e.g., hypertension, hyperlipidemia, diabetes mellitus, smoking). (label Abakavir dan lamivudin, Peringatan dan perhatian)

  • AbataseptimunosupresanModerat

    When receiving intravenous ORENCIA, patients that require blood glucose monitoring should be advised to consider methods that do not react with maltose, such as those based on glucose dehydrogenase nicotine adenine dinucleotide (GDH-NAD), glucose oxidase, or glucose hexokinase test methods. (label Abatasept, Interaksi obat)

  • AdalimumabimunosupresanModerat

    In controlled trials of other TNF blockers in adult patients at higher risk for malignancies (i.e., patients with COPD with a significant smoking history and cyclophosphamide-treated patients with Wegener’s granulomatosis), a greater portion of malignancies occurred in the TNF blocker group compared to the control group. (label Adalimumab, Peringatan dan perhatian)

  • AminofilinmetilxantinModerat

    …elevations for longer periods Hypothyroidism Liver disease; cirrhosis, acute hepatitis Reduced renal function in infants <3 months of age Sepsis with multi-organ failure Shock Cessation of Smoking Drug Interactions Adding a drug that inhibits theophylline metabolism (e.g., cimetidine, erythromycin, tacrine) or stopping a concurrently administered drug that enhances theophylline… (label Aminofilin, Peringatan)

  • Asam mefenamatOAINSModerat

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy, concomitant use of oral corticosteroids, anti-platelet drugs (such as aspirin), anticoagulants, or selective serotonin reuptake inhibitors (SSRIs), smoking, use of alcohol, older age, and poor general health status. (label Asam mefenamat, Peringatan dan perhatian)

  • BudesonidkortikosteroidModerat

    Patients with major risk factors for decreased bone mineral content, such as prolonged immobilization, family history of osteoporosis, post menopausal status, tobacco use, advance age, poor nutrition, or chronic use of drugs that can reduce bone mass (e.g., anticonvulsants, oral corticosteroids) should be monitored and treated with established standards of care. (label Budesonid, Peringatan dan perhatian)

  • Budesonid dan formoterolkortikosteroidModerat

    Patients with major risk factors for decreased bone mineral content, such as prolonged immobilization, family history of osteoporosis, postmenopausal status, tobacco use, advanced age, poor nutrition, or chronic use of drugs that can reduce bone mass (e.g., anticonvulsants, oral corticosteroids) should be monitored and treated with established standards of care. (label Budesonid dan formoterol, Peringatan dan perhatian)

  • BupropionantidepresanModerat

    Monitoring of blood pressure is recommended in patients who receive the combination of bupropion and nicotine replacement. (label Bupropion, Peringatan dan perhatian)

  • DiflunisalOAINSModerat

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (label Diflunisal, Peringatan)

  • DiklofenakOAINSModerat

    Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (label Diklofenak, Peringatan dan perhatian)

  • Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, antiplatelet drugs (such as aspirin), anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (label Diklofenak dan misoprostol, Peringatan dan perhatian)

  • EletriptantriptanModerat

    Perform a cardiovascular evaluation in triptan-naïve patients who have multiple cardiovascular risk factors (e.g., increased age, diabetes, hypertension, smoking, obesity, strong family history of CAD) prior to receiving RELPAX. (label Eletriptan, Peringatan dan perhatian)

  • EstazolambenzodiazepinModerat

    Smokers have an increased clearance of benzodiazepines as compared to nonsmokers; this was seen in studies with estazolam (see CLINICAL PHARMACOLOGY ). (label Estazolam, Interaksi obat)

  • EstradiolestrogenModerat

    Risk factors for arterial vascular disease (e.g., hypertension, diabetes mellitus, tobacco use, hypercholesterolemia, and obesity) and/or venous thromboembolism (e.g., personal history or family history of VTE, obesity, and systemic lupus erythematosus) should be managed appropriately. a. (label Estradiol, Peringatan)

  • Manage appropriately any risk factors for arterial vascular disease (for example, hypertension, diabetes mellitus, tobacco use, hypercholesterolemia, and obesity) and/or venous thromboembolism (VTE) (for example, personal history or family history of VTE, obesity, and systemic lupus erythematosus). (label Estradiol dan noretisteron, Peringatan dan perhatian)

  • Risk factors for arterial vascular disease (e.g., hypertension, diabetes mellitus, tobacco use, hypercholesterolemia, and obesity) and/or venous thromboembolism (e.g., personal history or family history of VTE, obesity, and systemic lupus erythematosus) should be managed appropriately. (label Estrogen teresterifikasi dan metiltestosteron, Peringatan)

  • Estrogen terkonjugasiestrogenModerat

    Risk factors for arterial vascular disease (for example, hypertension, diabetes mellitus, tobacco use, hypercholesterolemia, and obesity) and/or venous thromboembolism (VTE) (for example, personal history or family history of VTE, obesity, and systemic lupus erythematosus) should be managed appropriately. a. (label Estrogen terkonjugasi, Peringatan)

  • Risk factors for arterial vascular disease (for example, hypertension, diabetes mellitus, tobacco use, hypercholesterolemia, and obesity) and/or VTE (for example, personal history or family history of VTE, obesity, and systemic lupus erythematosus) should be managed appropriately. (label Estrogen terkonjugasi dan bazedoksifen, Peringatan dan perhatian)

  • EtodolakOAINSModerat

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (label Etodolak, Peringatan)

  • FenoprofenOAINSModerat

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (label Fenoprofen, Peringatan dan perhatian)

  • FlurbiprofenOAINSModerat

    Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking, use of alcohol, older age, and poor general health status. (label Flurbiprofen, Peringatan dan perhatian)

  • FlutamidandrogenModerat

    In patients susceptible to aniline toxicity (e.g. persons with glucose-6-phosphate dehydrogenase deficiency, hemoglobin M disease and smokers), monitoring of methemoglobin levels should be considered. (label Flutamid, Peringatan)

  • FlutikasonkortikosteroidModerat

    Patients with major risk factors for decreased bone mineral content, such as prolonged immobilization, family history of osteoporosis, postmenopausal status, tobacco use, advanced age, poor nutrition, or chronic use of drugs that can reduce bone mass (e.g., anticonvulsants, oral corticosteroids), should be monitored and treated with established standards of care. (label Flutikason, Peringatan dan perhatian)

  • FluvoksaminSSRIModerat

    Theophylline: The effect of steady-state fluvoxamine (50 mg bid) on the pharmacokinetics of a single dose of theophylline (375 mg as 442 mg aminophylline) was evaluated in 12 healthy non-smoking, male volunteers. (label Fluvoksamin, Peringatan dan perhatian)

  • FrovatriptantriptanModerat

    Perform a cardiovascular evaluation in triptan-naïve patients who have multiple cardiovascular risk factors (e.g., increased age, diabetes, hypertension, smoking, obesity, strong family history of CAD) prior to receiving frovatriptan succinate. (label Frovatriptan, Peringatan dan perhatian)

  • Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (label Hidrokodon dan ibuprofen, Peringatan)

  • IbuprofenOAINSModerat

    Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (label Ibuprofen, Peringatan dan perhatian)

  • Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (label Ibuprofen dan famotidin, Peringatan dan perhatian)

  • IndometasinOAINSModerat

    Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (label Indometasin, Peringatan dan perhatian)

  • In both cases, a prior history of heavy tobacco use was identified as a risk factor for lung cancer. (label Insulin reguler (manusia), Peringatan dan perhatian)

  • KetoprofenOAINSModerat

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (label Ketoprofen, Peringatan)

  • KetorolakOAINSModerat

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (label Ketorolak, Peringatan dan perhatian)

  • KlorazepatbenzodiazepinModerat

    In addition, the majority of more recent case-control and cohort studies of benzodiazepine use during pregnancy, which were adjusted for confounding exposures to alcohol, tobacco and other medications, have not confirmed these findings. (label Klorazepat, Interaksi obat)

  • KlordiazepoksidbenzodiazepinModerat

    In addition, the majority of more recent case-control and cohort studies of benzodiazepine use during pregnancy, which were adjusted for confounding exposures to alcohol, tobacco and other medications, have not confirmed these findings. (label Klordiazepoksid, Interaksi obat)

  • KlozapinantipsikotikModerat

    • Discontinuation of CYP1A2 or CYP3A4 Inducers: Consider reducing CLOZARIL dose when CYP1A2 inducers (e.g., tobacco smoke) or CYP3A4 inducers (e.g., carbamazepine) are discontinued. (label Klozapin, Interaksi obat)

  • KuininantimalariaModerat

    Cigarette Smoking (CYP1A2 Inducer) In healthy male heavy smokers, the mean quinine AUC following a single 600 mg dose was 44% lower, the mean C max was 18% lower, and the elimination half-life was shorter (7.5 hours versus 12 hours) than in their non-smoking counterparts. (label Kuinin, Interaksi obat)

  • Patients with known risk factors, including prior thrombosis, may be at greater risk and actions should be taken to try to minimize all modifiable factors (e.g. hyperlipidemia, hypertension, smoking). (label Lenalidomid, Peringatan dan perhatian)

  • MedroksiprogesteronprogestinModerat

    MPA Injectable Suspension, USP can pose an additional risk in patients with risk factors for osteoporosis (e.g., metabolic bone disease, chronic alcohol and/or tobacco use, anorexia nervosa, strong family history of osteoporosis or chronic use of drugs that can reduce bone mass such as anticonvulsants or corticosteroids). (label Medroksiprogesteron, Peringatan dan perhatian)

  • MeloksikamOAINSModerat

    Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (label Meloksikam, Peringatan dan perhatian)

  • Metilergometrinalkaloid ergotModerat

    Coronary artery disease Patients with coronary artery disease or risk factors for coronary artery disease (e.g., smoking, obesity, diabetes, high cholesterol) may be more susceptible to developing myocardial ischemia and infarction associated with methylergonovine-induced vasospasm. (label Metilergometrin, Peringatan)

  • NabumetonOAINSModerat

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (label Nabumeton, Peringatan)

  • NaproksenOAINSModerat

    Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (label Naproksen, Peringatan dan perhatian)

  • Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (label Naproksen dan esomeprazol, Peringatan dan perhatian)

  • NaratriptantriptanModerat

    Perform a cardiovascular evaluation in triptan-naive patients who have multiple cardiovascular risk factors (e.g., increased age, diabetes, hypertension, smoking, obesity, strong family history of CAD) prior to receiving naratriptan tablets. (label Naratriptan, Peringatan dan perhatian)

  • NoretisteronprogestinModerat

    WARNINGS Cigarette smoking increases the risk of serious cardiovascular disease. (label Noretisteron, Peringatan)

  • OksaprozinOAINSModerat

    Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, antiplatelet drugs (such as aspirin), anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (label Oksaprozin, Peringatan dan perhatian)

  • OlanzapinantipsikotikModerat

    This results in a mean increase in olanzapine Cmax following fluvoxamine of 54% in female nonsmokers and 77% in male smokers. (label Olanzapin, Interaksi obat)

  • Olanzapin dan fluoksetinantipsikotikModerat

    This results in a mean increase in olanzapine C max following fluvoxamine administration of 54% in female nonsmokers and 77% in male smokers. (label Olanzapin dan fluoksetin, Interaksi obat)

  • OmalizumabModerat

    The impact of longer exposure to omalizumab products or use in patients at higher risk for malignancy (e.g., elderly, current smokers) is not known. (label Omalizumab, Peringatan dan perhatian)

  • Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy, concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (label Parasetamol dan ibuprofen, Peringatan dan perhatian)

  • Tobacco Smoking tobacco could enhance the metabolic clearance rate of pentazocine reducing the clinical effectiveness of a standard dose of pentazocine. (label Pentazosin dan nalokson, Interaksi obat)

  • PiroksikamOAINSModerat

    Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, antiplatelet drugs (such as aspirin), anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (label Piroksikam, Peringatan dan perhatian)

  • Patients with known risk factors, including prior thrombosis, may be at greater risk, and actions should be taken to try to minimize all modifiable factors (e.g., hyperlipidemia, hypertension, smoking). (label Pomalidomid, Peringatan dan perhatian)

  • PropafenonantiaritmiaModerat

    Drugs that inhibit these CYP pathways (such as desipramine, paroxetine, ritonavir, sertraline for CYP2D6; ketoconazole, erythromycin, saquinavir, and grapefruit juice for CYP3A4; and amiodarone and tobacco smoke for CYP1A2) can be expected to cause increased plasma levels of propafenone. (label Propafenon, Peringatan dan perhatian)

  • Propranololpenyekat betaModerat

    CYP1A2 and CYP2C19 Inducers: CYP1A2 inducers (e.g., phenytoin, montelukast, smoking) and CYP2C19 inducers (e.g. rifampin) decrease the plasma levels of propranolol resulting in a loss of efficacy [see Clinical Pharmacology ( 12.7 )] . (label Propranolol, Interaksi obat)

  • Raloksifenmodulator reseptor estrogen selektifModerat

    The risk-benefit balance should be considered in women at risk for stroke, such as prior stroke or transient ischemic attack (TIA), atrial fibrillation, hypertension, or cigarette smoking [see Clinical Studies ( 14.5 )] . (label Raloksifen, Peringatan dan perhatian)

  • RiosiguatvasodilatorModerat

    Pharmacokinetic Interactions with Adempas Smoking: Plasma concentrations in smokers are reduced by 50% to 60% compared to nonsmokers. (label Riosiguat, Interaksi obat)

  • Ritlesitinibpenghambat JAKModerat

    In this study, current or past smokers had an additional increased risk of overall malignancies. (label Ritlesitinib, Peringatan dan perhatian)

  • RizatriptantriptanModerat

    Triptan-naïve patients who have multiple cardiovascular risk factors (e.g., increased age, diabetes, hypertension, smoking, obesity, strong family history of CAD) should have a cardiovascular evaluation prior to receiving MAXALT. (label Rizatriptan, Peringatan dan perhatian)

  • Ropinirolagonis dopaminModerat

    Cigarette smoking is expected to increase the clearance of ropinirole since CYP1A2 is known to be induced by smoking hormone replacement therapy [ see Clinical Pharmacology ( 12.3 ) ]. (label Ropinirol, Interaksi obat)

  • Ruksolitinibpenghambat JAKModerat

    Secondary Malignancies: Monitor for development of secondary malignancies, particularly in patients who are current or past smokers. (label Ruksolitinib, Peringatan dan perhatian)

  • SalsalatOAINSModerat

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (label Salsalat, Peringatan)

  • SelekoksibOAINSModerat

    Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, antiplatelet drugs (such as aspirin), anticoagulants; or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (label Selekoksib, Peringatan dan perhatian)

  • SulindakOAINSModerat

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (label Sulindak, Peringatan)

  • SumatriptantriptanModerat

    Perform a cardiovascular evaluation in triptan-naive patients who have multiple cardiovascular risk factors (e.g., increased age, diabetes, hypertension, smoking, obesity, strong family history of CAD) prior to receiving IMITREX tablets. (label Sumatriptan, Peringatan dan perhatian)

  • Perform a cardiovascular evaluation in patients who have multiple cardiovascular risk factors (e.g., increased age, diabetes, hypertension, smoking, obesity, strong family history of CAD) prior to receiving sumatriptan and naproxen sodium tablets. (label Sumatriptan dan naproksen, Peringatan dan perhatian)

  • TeofilinmetilxantinModerat

    Cessation of Smoking: Drug Interactions: Adding a drug that inhibits theophylline metabolism (e.g., cimetidine, erythromycin, tacrine) or stopping a concurrently administered drug that enhances theophylline metabolism (e.g., carbamazepine, rifampin). (label Teofilin, Peringatan)

  • TolmetinOAINSModerat

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (label Tolmetin, Peringatan)

  • WarfarinantikoagulanModerat

    …contraceptives, phenylpropanolamine, propafenone, propranolol, terbinafine, thiabendazole, ticlopidine, verapamil, zileuton montelukast, moricizine, omeprazole, phenobarbital, phenytoin, cigarette smoking CYP3A4 alprazolam, amiodarone, amlodipine, amprenavir, aprepitant, atorvastatin, atazanavir, bicalutamide, cilostazol, cimetidine, ciprofloxacin, clarithromycin, conivaptan,… (label Warfarin, Interaksi obat)

  • ZolmitriptantriptanModerat

    Perform a cardiovascular evaluation in triptan-naïve patients who have multiple cardiovascular risk factors (e.g., increased age, diabetes, hypertension, smoking, obesity, strong family history of CAD) prior to receiving zolmitriptan. (label Zolmitriptan, Peringatan dan perhatian)

Penyebutan minor (9)

  • Asam traneksamatantifibrinolitikMinor

    This is of particular concern in women who are obese or smoke cigarettes, especially smokers over 35 years of age. (label Asam traneksamat, Peringatan dan perhatian)

  • Dekstrometorfanobat serotonergikMinor

    Ask a doctor before use if you have chronic cough that lasts such as occurs with smoking, asthma, or emphysema cough that occurs with too much phlegm (mucus) Stop use and ask a doctor if cough lasts more than 7 days, comes back, or occurs with fever, rash, or headache that lasts. (label Dekstrometorfan, Peringatan)

  • Dihidroergotaminalkaloid ergotMinor

    Nicotine Nicotine may provoke vasoconstriction in some patients, predisposing to a greater ischemic response to ergot therapy. (label Dihidroergotamin, Interaksi obat)

  • Ergotamin dan kafeinalkaloid ergotMinor

    Nicotine may provoke vasoconstriction in some patients, predisposing to a greater ischemic response to ergot therapy. (label Ergotamin dan kafein, Interaksi obat)

  • HeparinantikoagulanMinor

    Other Interactions Digitalis, tetracyclines, nicotine, or antihistamines, or intravenous nitroglycerin may partially counteract the anticoagulant action of heparin sodium. (label Heparin, Interaksi obat)

  • InfliksimabimunosupresanMinor

    All patients had a history of heavy smoking [see Adverse Reactions (6.1) ] . (label Infliksimab, Peringatan dan perhatian)

  • Tobacco and other medications, have not confirmed these findings. (label Klordiazepoksid dan klidinium, Interaksi obat)

  • KuinidinantiaritmiaMinor

    Quinidine's pharmacokinetics are also unaffected by cigarette smoking. (label Kuinidin, Interaksi obat)

  • Naltrekson dan bupropionantagonis opioidMinor

    Some patients who stopped smoking may have been experiencing symptoms of nicotine withdrawal, including depressed mood. (label Naltrekson dan bupropion, Peringatan dan perhatian)

Periksa Tembakau dan merokok terhadap semua yang Anda gunakan. Tambahkan seluruh daftar Anda; setiap pasangan diperiksa sekaligus.

Buka di pemeriksa

Bukan nasihat medis. Tingkat keparahan mencerminkan kata-kata dalam label, bukan keadaan Anda. Tanda “mayor” bisa merupakan hal yang rutin di bawah pengawasan, dan tanda “minor” bisa menjadi penting pada dosis tinggi. Tanyakan kepada apoteker.