Danazol interactions

CONTRAINDICATIONS: Precocious puberty, prostatic carcinoma or other androgen-dependent neoplasm, prior allergic reaction to HCG. (Chorionic gonadotropin label, Contraindications)

These drugs include, but are not limited to, the following: the anticonvulsants carbamazepine, oxcarbazepine, phenobarbital, phenytoin the androgen receptor inhibitor enzalutamide the antimycobacterials rifampin, rifapentine the cytotoxic agent mitotane St. (Doravirine label, Contraindications)

Concomitant use of cyclosporine, danazol, or danazol [see Drug Interactions (7.1) ] . (Ezetimibe and simvastatin label, Contraindications)

Because of the ability of Type II 5α-reductase inhibitors to inhibit the conversion of testosterone to 5α-dihydrotestosterone (DHT), finasteride may cause abnormalities of the external genitalia of a male fetus of a pregnant female who receives finasteride. (Finasteride label, Contraindications)

…Voriconazole Erythromycin Clarithromycin Telithromycin HIV protease inhibitors Boceprevir Telaprevir Nefazodone Cobicistat-containing products Gemfibrozil Avoid with lovastatin Cyclosporine Danazol Do not exceed 20 mg lovastatin daily Diltiazem Dronedarone Verapamil Amiodarone Do not exceed 40 mg lovastatin daily Grapefruit juice Avoid grapefruit juice Immune-Mediated… (Lovastatin label, Warnings)

Concomitant use of cyclosporine, danazol or gemfibrozil [see Drug Interactions (7.1) ] . (Simvastatin label, Contraindications)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (Danazol label, Drug interactions)

The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (Danazol label, Drug interactions)

Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Therapy with danazol may cause an increase in carbamazepine levels in patients taking both drugs. (Danazol label, Drug interactions)

PRECAUTIONS General Induction of androgen secretion by hCG may cause fluid retention. (Choriogonadotropin alfa label, Precautions)

Free hormone concentrations, such as testosterone and estradiol, may be decreased. (Conjugated estrogens label, Precautions)

Free hormone concentrations, such as testosterone and estradiol, may be decreased. (Conjugated estrogens and bazedoxifene label, Warnings and precautions)

…methylprednisolone Allopurinol nicardipine itraconazole clarithromycin Amiodarone verapamil ketoconazole erythromycin Bromocriptine voriconazole quinupristin/ dalfopristin colchicine danazol imatinib metoclopramide nefazodone oral contraceptives HIV Protease Inhibitors The HIV protease inhibitors (e.g., indinavir, nelfinavir, ritonavir, and saquinavir) are known… (Cyclosporine label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Free hormone concentrations, such as testosterone and estradiol, may be decreased. (Estradiol and norethindrone label, Warnings and precautions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Anabolic steroids (particularly C-17 alkylated androgens such as oxymetholone, methandrostenolone, norethandrolone, and similar compounds)—enhanced tendency toward edema. (Fludrocortisone label, Drug interactions)

The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (Danazol label, Drug interactions)

For Men : Clinical monitoring for spermatogenesis utilizes the following indirect or direct measures: Serum testosterone level Semen analysis 5.11 FOLLISTIM Pen The FOLLISTIM Pen is intended only for use with FOLLISTIM AQ Cartridge. (Follitropin label, Warnings and precautions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Effect on QT/QTc Interval: Androgen deprivation therapy may prolong the QT interval. (Goserelin label, Warnings and precautions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Tumor Flare: Increased serum testosterone (~ 50% above baseline) may occur when initiating treatment with LUPRON DEPOT. (Leuprolide label, Warnings and precautions)

Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (Danazol label, Precautions)

Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (Danazol label, Precautions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (Danazol label, Precautions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

The following laboratory tests may be affected by progestins including MPA Injectable Suspension, USP: (a) Plasma and urinary steroid levels are decreased (e.g., progesterone, estradiol, pregnanediol, testosterone, cortisol). (Medroxyprogesterone label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (Danazol label, Precautions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (Danazol label, Drug interactions)

The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (Danazol label, Drug interactions)

Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (Danazol label, Precautions)

Reproductive effects: Include decreased testosterone and increased prolactin levels. (Ramelteon label, Warnings and precautions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

• Drugs that could increase sirolimus blood concentrations: Bromocriptine, cimetidine, cisapride, clotrimazole, danazol, diltiazem, fluconazole, letermovir, protease inhibitors (e.g., HIV and hepatitis C that include drugs such as ritonavir, indinavir, boceprevir, and telaprevir), metoclopramide, nicardipine, troleandomycin, verapamil • Drugs and other agents… (Sirolimus label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Abiraterone: Spironolactone binds to the androgen receptor and may increase prostate‑specific antigen (PSA) levels in abiraterone-treated prostate cancer patients. (Spironolactone and hydrochlorothiazide label, Drug interactions)

Danazol may raise the plasma levels of cyclosporin and tacrolimus, leading to an increase of the renal toxicity of these drugs. (Danazol label, Drug interactions)

Hypercalcemia in Patients with Metastatic Breast Cancer As with other additive hormonal therapy (estrogens and androgens), hypercalcemia has been reported in some breast cancer patients with bone metastases within a few weeks of starting treatment with tamoxifen. (Tamoxifen label, Warnings and precautions)

Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (Danazol label, Precautions)

Caution should be exercised when used with antidiabetic drugs. (Danazol label, Drug interactions)

Tumor Flare: Transient increase in serum testosterone levels can occur within the first few weeks of treatment. (Triptorelin label, Warnings and precautions)

Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (Danazol label, Drug interactions)

Drug Interactions: Prolongation of prothrombin time occurs in patients stabilized on warfarin. (Danazol label, Drug interactions)

Laboratory Tests: Danazol treatment may interfere with laboratory determinations of testosterone, androstenedione and dehydroepiandrosterone. (Danazol label, Precautions)