Interações de Danazol
Danazol, androgênio, tem 80 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 6; moderadas: 73; leves: 1; casos em que uma bula relata não haver interação significativa: 0). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.
Interações segundo a bula
Interações graves (6)
These drugs include, but are not limited to, the following: the anticonvulsants carbamazepine, oxcarbazepine, phenobarbital, phenytoin the androgen receptor inhibitor enzalutamide the antimycobacterials rifampin, rifapentine the cytotoxic agent mitotane St. (bula de Doravirina, Contraindicações)
Concomitant use of cyclosporine, danazol, or danazol [see Drug Interactions (7.1) ] . (bula de Ezetimiba + sinvastatina, Contraindicações)
Because of the ability of Type II 5α-reductase inhibitors to inhibit the conversion of testosterone to 5α-dihydrotestosterone (DHT), finasteride may cause abnormalities of the external genitalia of a male fetus of a pregnant female who receives finasteride. (bula de Finasterida, Contraindicações)
CONTRAINDICATIONS: Precocious puberty, prostatic carcinoma or other androgen-dependent neoplasm, prior allergic reaction to HCG. (bula de Gonadotrofina coriônica, Contraindicações)
…Voriconazole Erythromycin Clarithromycin Telithromycin HIV protease inhibitors Boceprevir Telaprevir Nefazodone Cobicistat-containing products Gemfibrozil Avoid with lovastatin Cyclosporine Danazol Do not exceed 20 mg lovastatin daily Diltiazem Dronedarone Verapamil Amiodarone Do not exceed 40 mg lovastatin daily Grapefruit juice Avoid grapefruit juice Immune-Mediated… (bula de Lovastatina, Advertências)
Concomitant use of cyclosporine, danazol or gemfibrozil [see Drug Interactions (7.1) ] . (bula de Sinvastatina, Contraindicações)
Interações moderadas (73)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
- AlfacoriogonadotropinaModerada
PRECAUTIONS General Induction of androgen secretion by hCG may cause fluid retention. (bula de Alfacoriogonadotropina, Precauções)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (bula de Danazol, Interações medicamentosas)
The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (bula de Danazol, Interações medicamentosas)
Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Therapy with danazol may cause an increase in carbamazepine levels in patients taking both drugs. (bula de Danazol, Interações medicamentosas)
…methylprednisolone Allopurinol nicardipine itraconazole clarithromycin Amiodarone verapamil ketoconazole erythromycin Bromocriptine voriconazole quinupristin/ dalfopristin colchicine danazol imatinib metoclopramide nefazodone oral contraceptives HIV Protease Inhibitors The HIV protease inhibitors (e.g., indinavir, nelfinavir, ritonavir, and saquinavir) are known… (bula de Ciclosporina, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Abiraterone: Spironolactone binds to the androgen receptor and may increase prostate‑specific antigen (PSA) levels in abiraterone-treated prostate cancer patients. (bula de Espironolactona + hidroclorotiazida, Interações medicamentosas)
Free hormone concentrations, such as testosterone and estradiol, may be decreased. (bula de Estradiol + noretisterona, Advertências e precauções)
Free hormone concentrations, such as testosterone and estradiol, may be decreased. (bula de Estrogênios conjugados, Precauções)
Free hormone concentrations, such as testosterone and estradiol, may be decreased. (bula de Estrogênios conjugados + bazedoxifeno, Advertências e precauções)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Anabolic steroids (particularly C-17 alkylated androgens such as oxymetholone, methandrostenolone, norethandrolone, and similar compounds)—enhanced tendency toward edema. (bula de Fludrocortisona, Interações medicamentosas)
The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (bula de Danazol, Interações medicamentosas)
- FolitropinaModerada
For Men : Clinical monitoring for spermatogenesis utilizes the following indirect or direct measures: Serum testosterone level Semen analysis 5.11 FOLLISTIM Pen The FOLLISTIM Pen is intended only for use with FOLLISTIM AQ Cartridge. (bula de Folitropina, Advertências e precauções)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
- GosserrelinaModerada
Effect on QT/QTc Interval: Androgen deprivation therapy may prolong the QT interval. (bula de Gosserrelina, Advertências e precauções)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
- LeuprorrelinaModerada
Tumor Flare: Increased serum testosterone (~ 50% above baseline) may occur when initiating treatment with LUPRON DEPOT. (bula de Leuprorrelina, Advertências e precauções)
Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (bula de Danazol, Precauções)
Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (bula de Danazol, Precauções)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (bula de Danazol, Precauções)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
The following laboratory tests may be affected by progestins including MPA Injectable Suspension, USP: (a) Plasma and urinary steroid levels are decreased (e.g., progesterone, estradiol, pregnanediol, testosterone, cortisol). (bula de Medroxiprogesterona, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (bula de Danazol, Interações medicamentosas)
The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (bula de Danazol, Interações medicamentosas)
Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (bula de Danazol, Precauções)
Reproductive effects: Include decreased testosterone and increased prolactin levels. (bula de Ramelteona, Advertências e precauções)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
• Drugs that could increase sirolimus blood concentrations: Bromocriptine, cimetidine, cisapride, clotrimazole, danazol, diltiazem, fluconazole, letermovir, protease inhibitors (e.g., HIV and hepatitis C that include drugs such as ritonavir, indinavir, boceprevir, and telaprevir), metoclopramide, nicardipine, troleandomycin, verapamil • Drugs and other agents… (bula de Sirolimo, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
Danazol may raise the plasma levels of cyclosporin and tacrolimus, leading to an increase of the renal toxicity of these drugs. (bula de Danazol, Interações medicamentosas)
Hypercalcemia in Patients with Metastatic Breast Cancer As with other additive hormonal therapy (estrogens and androgens), hypercalcemia has been reported in some breast cancer patients with bone metastases within a few weeks of starting treatment with tamoxifen. (bula de Tamoxifeno, Advertências e precauções)
Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (bula de Danazol, Precauções)
Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (bula de Danazol, Precauções)
Caution should be exercised when used with antidiabetic drugs. (bula de Danazol, Interações medicamentosas)
- TriptorrelinaModerada
Tumor Flare: Transient increase in serum testosterone levels can occur within the first few weeks of treatment. (bula de Triptorrelina, Advertências e precauções)
Drug Interactions: Prolongation of prothrombin time occurs in patients stabilized on warfarin. (bula de Danazol, Interações medicamentosas)
Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (bula de Danazol, Interações medicamentosas)
Menções leves (1)
Laboratory Tests: Danazol treatment may interfere with laboratory determinations of testosterone, androstenedione and dehydroepiandrosterone. (bula de Danazol, Precauções)
Verifique Danazol com tudo o que você toma. Adicione sua lista completa; todos os pares são verificados de uma vez.
Abrir no verificadorNão é aconselhamento médico. A gravidade reflete a redação da bula, não as suas circunstâncias. Um alerta “grave” pode ser rotina sob supervisão, e um “leve” pode ser importante em doses altas. Pergunte a um farmacêutico.