Danazol : interactions médicamenteuses

These drugs include, but are not limited to, the following: the anticonvulsants carbamazepine, oxcarbazepine, phenobarbital, phenytoin the androgen receptor inhibitor enzalutamide the antimycobacterials rifampin, rifapentine the cytotoxic agent mitotane St. (notice Doravirine, Contre-indications)

Concomitant use of cyclosporine, danazol, or danazol [see Drug Interactions (7.1) ] . (notice Ézétimibe et simvastatine, Contre-indications)

Because of the ability of Type II 5α-reductase inhibitors to inhibit the conversion of testosterone to 5α-dihydrotestosterone (DHT), finasteride may cause abnormalities of the external genitalia of a male fetus of a pregnant female who receives finasteride. (notice Finastéride, Contre-indications)

CONTRAINDICATIONS: Precocious puberty, prostatic carcinoma or other androgen-dependent neoplasm, prior allergic reaction to HCG. (notice Gonadotrophine chorionique, Contre-indications)

…Voriconazole Erythromycin Clarithromycin Telithromycin HIV protease inhibitors Boceprevir Telaprevir Nefazodone Cobicistat-containing products Gemfibrozil Avoid with lovastatin Cyclosporine Danazol Do not exceed 20 mg lovastatin daily Diltiazem Dronedarone Verapamil Amiodarone Do not exceed 40 mg lovastatin daily Grapefruit juice Avoid grapefruit juice Immune-Mediated… (notice Lovastatine, Mises en garde)

Concomitant use of cyclosporine, danazol or gemfibrozil [see Drug Interactions (7.1) ] . (notice Simvastatine, Contre-indications)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (notice Danazol, Interactions médicamenteuses)

The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (notice Danazol, Interactions médicamenteuses)

Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Therapy with danazol may cause an increase in carbamazepine levels in patients taking both drugs. (notice Danazol, Interactions médicamenteuses)

PRECAUTIONS General Induction of androgen secretion by hCG may cause fluid retention. (notice Choriogonadotropine alfa, Précautions)

…methylprednisolone Allopurinol nicardipine itraconazole clarithromycin Amiodarone verapamil ketoconazole erythromycin Bromocriptine voriconazole quinupristin/ dalfopristin colchicine danazol imatinib metoclopramide nefazodone oral contraceptives HIV Protease Inhibitors The HIV protease inhibitors (e.g., indinavir, nelfinavir, ritonavir, and saquinavir) are known… (notice Ciclosporine, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Free hormone concentrations, such as testosterone and estradiol, may be decreased. (notice Estradiol et noréthistérone, Mises en garde et précautions)

Free hormone concentrations, such as testosterone and estradiol, may be decreased. (notice Estrogènes conjugués, Précautions)

Free hormone concentrations, such as testosterone and estradiol, may be decreased. (notice Estrogènes conjugués et bazédoxifène, Mises en garde et précautions)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Anabolic steroids (particularly C-17 alkylated androgens such as oxymetholone, methandrostenolone, norethandrolone, and similar compounds)—enhanced tendency toward edema. (notice Fludrocortisone, Interactions médicamenteuses)

The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (notice Danazol, Interactions médicamenteuses)

For Men : Clinical monitoring for spermatogenesis utilizes the following indirect or direct measures: Serum testosterone level Semen analysis 5.11 FOLLISTIM Pen The FOLLISTIM Pen is intended only for use with FOLLISTIM AQ Cartridge. (notice Follitropine, Mises en garde et précautions)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Effect on QT/QTc Interval: Androgen deprivation therapy may prolong the QT interval. (notice Goséréline, Mises en garde et précautions)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Tumor Flare: Increased serum testosterone (~ 50% above baseline) may occur when initiating treatment with LUPRON DEPOT. (notice Leuproréline, Mises en garde et précautions)

Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (notice Danazol, Précautions)

Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (notice Danazol, Précautions)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (notice Danazol, Précautions)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

The following laboratory tests may be affected by progestins including MPA Injectable Suspension, USP: (a) Plasma and urinary steroid levels are decreased (e.g., progesterone, estradiol, pregnanediol, testosterone, cortisol). (notice Médroxyprogestérone, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (notice Danazol, Interactions médicamenteuses)

The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (notice Danazol, Interactions médicamenteuses)

Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (notice Danazol, Précautions)

Reproductive effects: Include decreased testosterone and increased prolactin levels. (notice Rameltéon, Mises en garde et précautions)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

• Drugs that could increase sirolimus blood concentrations: Bromocriptine, cimetidine, cisapride, clotrimazole, danazol, diltiazem, fluconazole, letermovir, protease inhibitors (e.g., HIV and hepatitis C that include drugs such as ritonavir, indinavir, boceprevir, and telaprevir), metoclopramide, nicardipine, troleandomycin, verapamil • Drugs and other agents… (notice Sirolimus, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Abiraterone: Spironolactone binds to the androgen receptor and may increase prostate‑specific antigen (PSA) levels in abiraterone-treated prostate cancer patients. (notice Spironolactone et hydrochlorothiazide, Interactions médicamenteuses)

Danazol may raise the plasma levels of cyclosporin and tacrolimus, leading to an increase of the renal toxicity of these drugs. (notice Danazol, Interactions médicamenteuses)

Hypercalcemia in Patients with Metastatic Breast Cancer As with other additive hormonal therapy (estrogens and androgens), hypercalcemia has been reported in some breast cancer patients with bone metastases within a few weeks of starting treatment with tamoxifen. (notice Tamoxifène, Mises en garde et précautions)

Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (notice Danazol, Précautions)

Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (notice Danazol, Précautions)

Caution should be exercised when used with antidiabetic drugs. (notice Danazol, Interactions médicamenteuses)

Tumor Flare: Transient increase in serum testosterone levels can occur within the first few weeks of treatment. (notice Triptoréline, Mises en garde et précautions)

Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (notice Danazol, Interactions médicamenteuses)

Drug Interactions: Prolongation of prothrombin time occurs in patients stabilized on warfarin. (notice Danazol, Interactions médicamenteuses)

Laboratory Tests: Danazol treatment may interfere with laboratory determinations of testosterone, androstenedione and dehydroepiandrosterone. (notice Danazol, Précautions)