Interaksi Danazol

Danazol, golongan androgen, memiliki 80 interaksi terdokumentasi dalam label FDA dan lembar fakta yang kami indeks: 6 mayor, 73 moderat, 1 minor, dan 0 dengan label yang melaporkan tidak ada interaksi bermakna. Setiap entri di bawah ini mengutip kalimat yang mendasarinya. Halaman obat ini adalah titik awal, bukan putusan untuk situasi Anda.

Interaksi dari label

Interaksi mayor (6)

  • DoravirinantiretroviralMayor

    These drugs include, but are not limited to, the following: the anticonvulsants carbamazepine, oxcarbazepine, phenobarbital, phenytoin the androgen receptor inhibitor enzalutamide the antimycobacterials rifampin, rifapentine the cytotoxic agent mitotane St. (label Doravirin, Kontraindikasi)

  • Concomitant use of cyclosporine, danazol, or danazol [see Drug Interactions (7.1) ] . (label Ezetimib dan simvastatin, Kontraindikasi)

  • Finasteridpenghambat 5-alfa reduktaseMayor

    Because of the ability of Type II 5α-reductase inhibitors to inhibit the conversion of testosterone to 5α-dihydrotestosterone (DHT), finasteride may cause abnormalities of the external genitalia of a male fetus of a pregnant female who receives finasteride. (label Finasterid, Kontraindikasi)

  • CONTRAINDICATIONS: Precocious puberty, prostatic carcinoma or other androgen-dependent neoplasm, prior allergic reaction to HCG. (label Gonadotropin korionik, Kontraindikasi)

  • LovastatinstatinMayor

    …Voriconazole Erythromycin Clarithromycin Telithromycin HIV protease inhibitors Boceprevir Telaprevir Nefazodone Cobicistat-containing products Gemfibrozil Avoid with lovastatin Cyclosporine Danazol Do not exceed 20 mg lovastatin daily Diltiazem Dronedarone Verapamil Amiodarone Do not exceed 40 mg lovastatin daily Grapefruit juice Avoid grapefruit juice Immune-Mediated… (label Lovastatin, Peringatan)

  • SimvastatinstatinMayor

    Concomitant use of cyclosporine, danazol or gemfibrozil [see Drug Interactions (7.1) ] . (label Simvastatin, Kontraindikasi)

Interaksi moderat (73)

  • AkarbosaantidiabetesModerat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Alogliptinpenghambat DPP-4Moderat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Alogliptin dan metforminpenghambat DPP-4Moderat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Amlodipin dan atorvastatinpenghambat kanal kalsium dihidropiridinModerat

    The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (label Danazol, Interaksi obat)

  • AtorvastatinstatinModerat

    The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (label Danazol, Interaksi obat)

  • Beksagliflozinpenghambat SGLT2Moderat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Dapagliflozinpenghambat SGLT2Moderat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Dapagliflozin dan metforminpenghambat SGLT2Moderat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Dokserkalsiferolanalog vitamin DModerat

    Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (label Danazol, Interaksi obat)

  • Dulaglutidagonis reseptor GLP-1Moderat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Eksenatidagonis reseptor GLP-1Moderat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Empagliflozinpenghambat SGLT2Moderat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Empagliflozin dan metforminpenghambat SGLT2Moderat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Free hormone concentrations, such as testosterone and estradiol, may be decreased. (label Estradiol dan noretisteron, Peringatan dan perhatian)

  • Estrogen terkonjugasiestrogenModerat

    Free hormone concentrations, such as testosterone and estradiol, may be decreased. (label Estrogen terkonjugasi, Perhatian)

  • Free hormone concentrations, such as testosterone and estradiol, may be decreased. (label Estrogen terkonjugasi dan bazedoksifen, Peringatan dan perhatian)

  • FludrokortisonkortikosteroidModerat

    Anabolic steroids (particularly C-17 alkylated androgens such as oxymetholone, methandrostenolone, norethandrolone, and similar compounds)—enhanced tendency toward edema. (label Fludrokortison, Interaksi obat)

  • FluvastatinstatinModerat

    The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (label Danazol, Interaksi obat)

  • FolitropinModerat

    For Men : Clinical monitoring for spermatogenesis utilizes the following indirect or direct measures: Serum testosterone level Semen analysis 5.11 FOLLISTIM Pen The FOLLISTIM Pen is intended only for use with FOLLISTIM AQ Cartridge. (label Folitropin, Peringatan dan perhatian)

  • GlibenklamidsulfonilureaModerat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Glibenklamid dan metforminsulfonilureaModerat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • GlimepiridsulfonilureaModerat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • GlipizidsulfonilureaModerat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Glipizid dan metforminsulfonilureaModerat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • GoserelinModerat

    Effect on QT/QTc Interval: Androgen deprivation therapy may prolong the QT interval. (label Goserelin, Peringatan dan perhatian)

  • Insulin aspartinsulinModerat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Insulin degludekinsulinModerat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Insulin detemirinsulinModerat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Insulin glargininsulinModerat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Insulin lisproinsulinModerat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Kalsipotriolanalog vitamin DModerat

    Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (label Danazol, Interaksi obat)

  • Kalsitriolanalog vitamin DModerat

    Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (label Danazol, Interaksi obat)

  • Kanagliflozinpenghambat SGLT2Moderat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • KarbamazepinantikonvulsanModerat

    Therapy with danazol may cause an increase in carbamazepine levels in patients taking both drugs. (label Danazol, Interaksi obat)

  • PRECAUTIONS General Induction of androgen secretion by hCG may cause fluid retention. (label Koriogonadotropin alfa, Perhatian)

  • Tumor Flare: Increased serum testosterone (~ 50% above baseline) may occur when initiating treatment with LUPRON DEPOT. (label Leuprorelin, Peringatan dan perhatian)

  • Levotiroksinhormon tiroidModerat

    Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (label Danazol, Perhatian)

  • Levotiroksin dan liotironinhormon tiroidModerat

    Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (label Danazol, Perhatian)

  • Linagliptinpenghambat DPP-4Moderat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Linagliptin dan metforminpenghambat DPP-4Moderat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Liotironinhormon tiroidModerat

    Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (label Danazol, Perhatian)

  • Liraglutidagonis reseptor GLP-1Moderat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • MedroksiprogesteronprogestinModerat

    The following laboratory tests may be affected by progestins including MPA Injectable Suspension, USP: (a) Plasma and urinary steroid levels are decreased (e.g., progesterone, estradiol, pregnanediol, testosterone, cortisol). (label Medroksiprogesteron, Interaksi obat)

  • MetforminbiguanidModerat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • MiglitolantidiabetesModerat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • NateglinidmeglitinidModerat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Parikalsitolanalog vitamin DModerat

    Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (label Danazol, Interaksi obat)

  • PioglitazontiazolidindionModerat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Pioglitazon dan glimepiridtiazolidindionModerat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Pioglitazon dan metformintiazolidindionModerat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • PitavastatinstatinModerat

    The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (label Danazol, Interaksi obat)

  • PravastatinstatinModerat

    The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (label Danazol, Interaksi obat)

  • Propiltiourasilobat antitiroidModerat

    Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (label Danazol, Perhatian)

  • Ramelteonsedatif-hipnotikModerat

    Reproductive effects: Include decreased testosterone and increased prolactin levels. (label Ramelteon, Peringatan dan perhatian)

  • RepaglinidmeglitinidModerat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • RosuvastatinstatinModerat

    The risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins such as simvastatin, atorvastatin and lovastatin. (label Danazol, Interaksi obat)

  • Saksagliptinpenghambat DPP-4Moderat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Saksagliptin dan metforminpenghambat DPP-4Moderat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Semaglutidagonis reseptor GLP-1Moderat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • SiklosporinimunosupresanModerat

    …methylprednisolone Allopurinol nicardipine itraconazole clarithromycin Amiodarone verapamil ketoconazole erythromycin Bromocriptine voriconazole quinupristin/ dalfopristin colchicine danazol imatinib metoclopramide nefazodone oral contraceptives HIV Protease Inhibitors The HIV protease inhibitors (e.g., indinavir, nelfinavir, ritonavir, and saquinavir) are known… (label Siklosporin, Interaksi obat)

  • SirolimusimunosupresanModerat

    • Drugs that could increase sirolimus blood concentrations: Bromocriptine, cimetidine, cisapride, clotrimazole, danazol, diltiazem, fluconazole, letermovir, protease inhibitors (e.g., HIV and hepatitis C that include drugs such as ritonavir, indinavir, boceprevir, and telaprevir), metoclopramide, nicardipine, troleandomycin, verapamil • Drugs and other agents… (label Sirolimus, Interaksi obat)

  • Sitagliptinpenghambat DPP-4Moderat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Sitagliptin dan metforminpenghambat DPP-4Moderat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Spironolakton dan hidroklorotiazidantagonis aldosteronModerat

    Abiraterone: Spironolactone binds to the androgen receptor and may increase prostate‑specific antigen (PSA) levels in abiraterone-treated prostate cancer patients. (label Spironolakton dan hidroklorotiazid, Interaksi obat)

  • TakrolimusimunosupresanModerat

    Danazol may raise the plasma levels of cyclosporin and tacrolimus, leading to an increase of the renal toxicity of these drugs. (label Danazol, Interaksi obat)

  • Tamoksifenmodulator reseptor estrogen selektifModerat

    Hypercalcemia in Patients with Metastatic Breast Cancer As with other additive hormonal therapy (estrogens and androgens), hypercalcemia has been reported in some breast cancer patients with bone metastases within a few weeks of starting treatment with tamoxifen. (label Tamoksifen, Peringatan dan perhatian)

  • Teriparatidhormon tiroidModerat

    Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (label Danazol, Perhatian)

  • Tiamazolobat antitiroidModerat

    Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (label Danazol, Perhatian)

  • Tirzepatidagonis reseptor GLP-1Moderat

    Caution should be exercised when used with antidiabetic drugs. (label Danazol, Interaksi obat)

  • Tumor Flare: Transient increase in serum testosterone levels can occur within the first few weeks of treatment. (label Triptorelin, Peringatan dan perhatian)

  • Vitamin DVitamin dan mineralModerat

    Danazol can increase the calcemic response to synthetic vitamin D analogs in primary hypoparathyroidism. (label Danazol, Interaksi obat)

  • WarfarinantikoagulanModerat

    Drug Interactions: Prolongation of prothrombin time occurs in patients stabilized on warfarin. (label Danazol, Interaksi obat)

Penyebutan minor (1)

  • TestosteronandrogenMinor

    Laboratory Tests: Danazol treatment may interfere with laboratory determinations of testosterone, androstenedione and dehydroepiandrosterone. (label Danazol, Perhatian)

Periksa Danazol terhadap semua yang Anda gunakan. Tambahkan seluruh daftar Anda; setiap pasangan diperiksa sekaligus.

Buka di pemeriksa

Bukan nasihat medis. Tingkat keparahan mencerminkan kata-kata dalam label, bukan keadaan Anda. Tanda “mayor” bisa merupakan hal yang rutin di bawah pengawasan, dan tanda “minor” bisa menjadi penting pada dosis tinggi. Tanyakan kepada apoteker.