Interacciones de Metolazona

Metolazona (Zaroxolyn), diurético tiazídico, tiene 423 interacciones documentadas en las etiquetas de la FDA y las hojas informativas que indexamos. Graves: 103; moderadas: 286; leves: 32; casos en los que una etiqueta indica que no hay ninguna interacción significativa: 2. Cada entrada de abajo cita la frase que la respalda. Esta página del medicamento es un punto de partida, no un veredicto sobre su situación.

Interacciones según la etiqueta

Interacciones graves (103)

  • AcebutololbetabloqueanteGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Ácido etacrínicodiurético de asaGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • AliskirenoantihipertensivoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Amiloridadiurético ahorrador de potasioGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Amlodipinobloqueador de los canales de calcio dihidropiridínicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Amlodipino y atorvastatinabloqueador de los canales de calcio dihidropiridínicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Amlodipino y benazeprilbloqueador de los canales de calcio dihidropiridínicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Amlodipino y olmesartánbloqueador de los canales de calcio dihidropiridínicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Amlodipino y valsartánbloqueador de los canales de calcio dihidropiridínicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • AtenololbetabloqueanteGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Atenolol y clortalidonabetabloqueanteGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Azilsartánantagonista de los receptores de la angiotensina II (ARA-II)Grave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Benazeprilinhibidor de la ECAGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Benazepril e hidroclorotiazidainhibidor de la ECAGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • BetaxololbetabloqueanteGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Bicarbonato de sodioantiácidoGrave

    Sodium bicarbonate injection is contraindicated in patients who are losing chloride by vomiting or from continuous gastrointestinal suction and in patients receiving diuretics known to produce a hypochloremic alkalosis. (etiqueta de Bicarbonato de sodio, Contraindicaciones)

  • BisoprololbetabloqueanteGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Bumetanidadiurético de asaGrave

    WARNING Bumetanide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. (etiqueta de Bumetanida, Advertencia en recuadro)

  • Candesartánantagonista de los receptores de la angiotensina II (ARA-II)Grave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Candesartán e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Grave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Captoprilinhibidor de la ECAGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • CarvedilolbetabloqueanteGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • CiclosporinainmunosupresorGrave

    Potassium-Sparing Diuretics Cyclosporine should not be used with potassium-sparing diuretics because hyperkalemia can occur. (etiqueta de Ciclosporina, Interacciones medicamentosas)

  • Citrato de potasiosuplemento de potasioGrave

    The following drug interactions may occur with potassium citrate: Potassium-sparing diuretics: concomitant administration should be avoided since the simultaneous administration of these agents can produce severe hyperkalemia (7.1) (etiqueta de Citrato de potasio, Interacciones medicamentosas)

  • Clonidinaagonista alfa-adrenérgicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Clorotiazidadiurético tiazídicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Clortalidonadiurético tiazídicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • ClozapinaantipsicóticoGrave

    Use CLOZARIL cautiously in patients with cardiovascular or cerebrovascular disease or conditions predisposing to hypotension (e.g., dehydration, use of antihypertensive medications) [see Dosage and Administration ( 2.2 , 2.6 ), Warnings and Precautions ( 5.2 )]. (etiqueta de Clozapina, Advertencia en recuadro)

  • Because the use of diuretics can accentuate the diminished intravascular volume, avoid diuretics except in the late phase of resolution. (etiqueta de Coriogonadotropina alfa, Advertencias)

  • CONTRAINDICATIONS PROGLYCEM is contraindicated in patients with: Functional hypoglycemia Hypersensitivity to diazoxide, any of the excipients in PROGLYCEM, or other thiazides (etiqueta de Diazóxido, Contraindicaciones)

  • Diltiazembloqueador de los canales de calcioGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • DofetilidaantiarrítmicoGrave

    In the DIAMOND trials, 1252 patients were treated with dofetilide and diuretics concomitantly, of whom 493 died compared to 508 deaths among the 1248 patients receiving placebo and diuretics. (etiqueta de Dofetilida, Interacciones medicamentosas)

  • DoxazosinaalfabloqueanteGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Droperidolantagonista de la dopaminaGrave

    Droperidol should be administered with extreme caution to patients who may be at risk for development of prolonged QT syndrome (e.g., congestive heart failure, bradycardia, use of a diuretic, cardiac hypertrophy, hypokalemia, hypomagnesemia, or administration of other drugs known to increase the QT interval). (etiqueta de Droperidol, Advertencia en recuadro)

  • Enalaprilinhibidor de la ECAGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Enalapril e hidroclorotiazidainhibidor de la ECAGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Enalaprilatoinhibidor de la ECAGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Eplerenonaantagonista de la aldosteronaGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Eptifibatidaantiagregante plaquetarioGrave

    …of active abnormal bleeding within the previous 30 days Severe hypertension (systolic blood pressure >200 mm Hg or diastolic blood pressure >110 mm Hg) not adequately controlled on antihypertensive therapy Major surgery within the preceding 6 weeks History of stroke within 30 days or any history of hemorrhagic stroke Current or planned administration of another… (etiqueta de Eptifibatida, Contraindicaciones)

  • Espironolactonaantagonista de la aldosteronaGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Espironolactona e hidroclorotiazidaantagonista de la aldosteronaGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Felodipinobloqueador de los canales de calcio dihidropiridínicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • FenoxibenzaminaalfabloqueanteGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Because the use of diuretics can accentuate the diminished intravascular volume, diuretics should be avoided except in the late phase of resolution as described below. (etiqueta de Folitropina, Advertencias y precauciones)

  • Fosinoprilinhibidor de la ECAGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Fosinopril e hidroclorotiazidainhibidor de la ECAGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Furosemidadiurético de asaGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • GentamicinaaminoglucósidoGrave

    The concurrent use of gentamicin with potent diuretics, such as ethacrynic acid or furosemide, should be avoided, since certain diuretics by themselves may cause ototoxicity. (etiqueta de Gentamicina, Advertencia en recuadro)

  • Guanfacinaagonista alfa-adrenérgicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • HidralazinavasodilatadorGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Hidroclorotiazidadiurético tiazídicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Indapamidadiurético tiazídicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Irbesartánantagonista de los receptores de la angiotensina II (ARA-II)Grave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Irbesartán e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Grave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Avoid diuretics or laxatives in patients with diarrhea. (etiqueta de Irinotecán, Advertencias y precauciones)

  • Isradipinobloqueador de los canales de calcio dihidropiridínicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Itraconazolantifúngico azólicoGrave

    Diuretics Eplerenone Contraindicated during and 2 weeks after TOLSURA treatment. (etiqueta de Itraconazol, Interacciones medicamentosas)

  • LabetalolbetabloqueanteGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Lisinoprilinhibidor de la ECAGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Lisinopril e hidroclorotiazidainhibidor de la ECAGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Lofexidinaagonista alfa-adrenérgicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Losartánantagonista de los receptores de la angiotensina II (ARA-II)Grave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Losartán e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Grave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • MecamilaminaantihipertensivoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • MetildopaantihipertensivoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • MetoprololbetabloqueanteGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • MinoxidilvasodilatadorGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Moexiprilinhibidor de la ECAGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • NadololbetabloqueanteGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • NebivololbetabloqueanteGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • NeomicinaaminoglucósidoGrave

    The concurrent use of neomycin with potent diuretics such as ethacrynic acid or furosemide should be avoided, since certain diuretics by themselves may cause ototoxicity. (etiqueta de Neomicina, Advertencia en recuadro)

  • Nicardipinobloqueador de los canales de calcio dihidropiridínicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Nifedipinobloqueador de los canales de calcio dihidropiridínicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Nisoldipinobloqueador de los canales de calcio dihidropiridínicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • NitroprusiatovasodilatadorGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Olmesartánantagonista de los receptores de la angiotensina II (ARA-II)Grave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Olmesartán e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Grave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Olmesartán, amlodipino e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Grave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Perindoprilinhibidor de la ECAGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • PindololbetabloqueanteGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • PrazosinaalfabloqueanteGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • PropranololbetabloqueanteGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Quinaprilinhibidor de la ECAGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Quinapril e hidroclorotiazidainhibidor de la ECAGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Ramiprilinhibidor de la ECAGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Sacubitrilo y valsartánantagonista de los receptores de la angiotensina II (ARA-II)Grave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Tadalafiloinhibidor de la PDE5Grave

    …coadministration of an alpha-blocker and CIALIS for the treatment of BPH has not been adequately studied, and due to the potential vasodilatory effects of combined use resulting in blood pressure lowering, the combination of CIALIS and alpha-blockers is not recommended for the treatment of BPH. [see Dosage and Administration ( 2.7 ), Drug Interactions ( 7.1 ),… (etiqueta de Tadalafilo, Advertencias y precauciones)

  • Telmisartánantagonista de los receptores de la angiotensina II (ARA-II)Grave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Telmisartán e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Grave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Telmisartán y amlodipinoantagonista de los receptores de la angiotensina II (ARA-II)Grave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • TerazosinaalfabloqueanteGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Tizanidinarelajante muscularGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Torasemidadiurético de asaGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Trandolaprilinhibidor de la ECAGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Triamterenodiurético ahorrador de potasioGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Triamtereno e hidroclorotiazidadiurético ahorrador de potasioGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Trióxido de arsénicofármaco que prolonga el intervalo QTGrave

    The risk of torsade de pointes is related to the extent of QTc prolongation, concomitant administration of QTc prolonging drugs, a history of torsade de pointes, pre-existing QTc interval prolongation, congestive heart failure, administration of potassium-wasting diuretics, or other conditions that result in hypokalemia or hypomagnesemia. (etiqueta de Trióxido de arsénico, Advertencias y precauciones)

  • Valsartánantagonista de los receptores de la angiotensina II (ARA-II)Grave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Valsartán e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Grave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • Verapamilobloqueador de los canales de calcioGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

Interacciones moderadas (286)

  • AcarbosaantidiabéticoModerada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Acetazolamidainhibidor de la anhidrasa carbónicaModerada

    Anticoagulants Metolazone, as well as other thiazide-like diuretics, may affect the hypoprothrombinemic response to anticoagulants; dosage adjustments may be necessary. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Ácido acetilsalicílico y dipiridamolantiagregante plaquetarioModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Ácido mefenámicoAINEModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Ácido zoledrónicobisfosfonatoModerada

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (etiqueta de Ácido zoledrónico, Advertencias y precauciones)

  • AdrenalinasimpaticomiméticoModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • AlcoholAlcoholModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • AlfuzosinaalfabloqueanteModerada

    Postural hypotension/syncope: Care should be taken in patients with symptomatic hypotension or who have had a hypotensive response to other medications or are concomitantly treated with antihypertensive medication or nitrates ( 5.1 ) (etiqueta de Alfuzosina, Advertencias y precauciones)

  • Alogliptinainhibidor de la DPP-4Moderada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Alogliptina y metforminainhibidor de la DPP-4Moderada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Alopurinolinhibidor de la xantina oxidasaModerada

    Hypersensitivity reactions to allopurinol tablets may be increased in patients with decreased kidney function receiving thiazide diuretics and allopurinol tablets concurrently. (etiqueta de Alopurinol, Advertencias y precauciones)

  • AmikacinaaminoglucósidoModerada

    Ethacrynic Acid, Furosemide, Urea, or Mannitol Some diuretics can enhance aminoglycoside toxicity by altering aminoglycoside concentrations in serum and tissue. (etiqueta de Amikacina, Interacciones medicamentosas)

  • AmiodaronaantiarrítmicoModerada

    Give special attention to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or in patients receiving concomitant diuretics and laxatives. (etiqueta de Amiodarona, Advertencias y precauciones)

  • Anfepramonaestimulante del SNCModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Anfetaminaestimulante del SNCModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Anfetamina y dexanfetaminaestimulante del SNCModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • ApixabánanticoagulanteModerada

    Anticoagulants Metolazone, as well as other thiazide-like diuretics, may affect the hypoprothrombinemic response to anticoagulants; dosage adjustments may be necessary. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Arformoterolagonista beta-adrenérgicoModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • ArgatrobánanticoagulanteModerada

    Anticoagulants Metolazone, as well as other thiazide-like diuretics, may affect the hypoprothrombinemic response to anticoagulants; dosage adjustments may be necessary. (etiqueta de Metolazona, Interacciones medicamentosas)

  • AripiprazolantipsicóticoModerada

    Antihypertensive Drugs Due to its alpha-adrenergic antagonism, aripiprazole has the potential to enhance the effect of certain antihypertensive agents. (etiqueta de Aripiprazol, Interacciones medicamentosas)

  • Armodafiniloestimulante del SNCModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Articaína y adrenalinaanestésico localModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • AsenapinaantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medications, patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), and patients… (etiqueta de Asenapina, Advertencias y precauciones)

  • Atomoxetinainhibidor de la recaptación de noradrenalinaModerada

    Antihypertensive Drugs Prevention or Management Increase the frequency of monitoring blood pressure and adjust atomoxetine oral solution dosage as clinically appropriate. (etiqueta de Atomoxetina, Interacciones medicamentosas)

  • Avanafiloinhibidor de la PDE5Moderada

    • Use of avanafil with alpha-blockers, other antihypertensives, or substantial amounts of alcohol (greater than 3 units) may lead to hypotension ( 2.3 , 5.6 , 5.7 ) (etiqueta de Avanafilo, Advertencias y precauciones)

  • Azelastina y fluticasonaantihistamínicoModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • BalsalazidasalicilatoModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • BeclometasonacorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Belladona y opioopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Benzfetaminaestimulante del SNCModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • BetametasonacorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Bexagliflozinainhibidor de SGLT2Moderada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • BivalirudinaanticoagulanteModerada

    Anticoagulants Metolazone, as well as other thiazide-like diuretics, may affect the hypoprothrombinemic response to anticoagulants; dosage adjustments may be necessary. (etiqueta de Metolazona, Interacciones medicamentosas)

  • BortezomibModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • BrexpiprazolantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medication), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etiqueta de Brexpiprazol, Advertencias y precauciones)

  • Brimonidinaagonista alfa-adrenérgicoModerada

    Antihypertensives/Cardiac Glycosides Because brimonidine tartrate ophthalmic solution 0.1% and 0.15% may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate ophthalmic solution 0.1% and 0.15% is advised. (etiqueta de Brimonidina, Interacciones medicamentosas)

  • Brimonidina y timololagonista alfa-adrenérgicoModerada

    Antihypertensives/Cardiac Glycosides Because brimonidine tartrate/timolol maleate ophthalmic solution may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate/timolol maleate ophthalmic solution is advised. (etiqueta de Brimonidina y timolol, Interacciones medicamentosas)

  • Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Bromocriptinaagonista de la dopaminaModerada

    Use caution in patients taking antihypertensive medications. (etiqueta de Bromocriptina, Advertencias y precauciones)

  • BudesonidacorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Budesonida y formoterolcorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Bupivacaína y adrenalinaanestésico localModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • BuprenorfinaopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Butalbital y paracetamolbarbitúricoModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • ButorfanolopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Calcitriolanálogo de la vitamina DModerada

    Thiazides Thiazides are known to induce hypercalcemia by the reduction of calcium excretion in urine. (etiqueta de Calcitriol, Interacciones medicamentosas)

  • Canagliflozinainhibidor de SGLT2Moderada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • CarbamazepinaanticonvulsivoModerada

    Elderly patients and patients treated with diuretics are at greater risk of developing hyponatremia. (etiqueta de Carbamazepina, Advertencias y precauciones)

  • CarbidopaModerada

    Symptomatic postural hypotension has occurred when carbidopa, given with levodopa or carbidopa-levodopa combination products, was added to the treatment of a patient receiving antihypertensive drugs. (etiqueta de Carbidopa, Interacciones medicamentosas)

  • Carbidopa y levodopafármaco dopaminérgicoModerada

    Antihypertensive drugs: May cause symptomatic postural hypotension. (etiqueta de Carbidopa y levodopa, Interacciones medicamentosas)

  • Carbidopa, levodopa y entacaponafármaco dopaminérgicoModerada

    Antihypertensive Agents Symptomatic postural hypotension has occurred when carbidopa/levodopa was added to the treatment of patients receiving antihypertensive drugs. (etiqueta de Carbidopa, levodopa y entacapona, Interacciones medicamentosas)

  • CariprazinaantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etiqueta de Cariprazina, Advertencias y precauciones)

  • CefepimacefalosporinaModerada

    Diuretics: Nephrotoxicity has been reported with concomitant administration of cephalosporins with potent diuretics such as furosemide. (etiqueta de Cefepima, Interacciones medicamentosas)

  • CeftazidimacefalosporinaModerada

    Drug Interactions Nephrotoxicity has been reported following concomitant administration of cephalosporins with aminoglycoside antibacterial drugs or potent diuretics such as furosemide. (etiqueta de Ceftazidima, Interacciones medicamentosas)

  • CelecoxibAINEModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • CiclesonidacorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Ciclobenzaprinarelajante muscularModerada

    …concomitant use of TONMYA with: MAO inhibitors may be life-threatening [see Contraindications (4) ] , Alcohol, barbiturates, and other CNS depressants may increase the risk of adverse reactions associated with these drugs, Tramadol may increase the seizure risk, Guanethidine or other similar acting drugs may block the antihypertensive action of these drugs. (etiqueta de Ciclobenzaprina, Interacciones medicamentosas)

  • CiclofosfamidainmunosupresorModerada

    …inhibitors: ACE inhibitors can cause leukopenia. ● Natalizumab ● Paclitaxel: Increased hematotoxicity has been reported when cyclophosphamide was administered after paclitaxel infusion. ● Thiazide diuretics ● Zidovudine Increased cardiotoxicity ● Anthracyclines ● Cytarabine ● Pentostatin ● Radiation therapy of the cardiac region ● Trastuzumab Increased pulmonary toxicity… (etiqueta de Ciclofosfamida, Interacciones medicamentosas)

  • Increase the dose of diuretics as needed [see Adverse Reactions (6) ] . (etiqueta de Ciclosilicato de sodio y zirconio, Advertencias y precauciones)

  • CitalopramISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume depleted may be at greater risk for developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (etiqueta de Citalopram, Advertencias y precauciones)

  • ClobetasolcorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • ClofarabinaantimetabolitoModerada

    Consider use of diuretics and/or albumin. (etiqueta de Clofarabina, Advertencias y precauciones)

  • ClorpromazinaantipsicóticoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Clorpromazina, Precauciones)

  • Drugs That Increase the Risk of Hypercalcemia Increase frequency of monitoring of calcium concentrations in patients taking concomitant Calcium Chloride Injection and other drugs that increase the risk of hypercalcemia (e.g., calcipotriene, estrogen, lithium, parathyroid hormone, teriparatide, thiazide diuretics, Vitamin A, and Vitamin D). (etiqueta de Cloruro de calcio, Interacciones medicamentosas)

  • CodeínaopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Colestiraminasecuestrador de ácidos biliaresModerada

    Drug Interactions Cholestyramine for Oral Suspension USP may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics (acidic), or propranolol (basic), as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins, and digitalis. (etiqueta de Colestiramina, Interacciones medicamentosas)

  • DabigatránanticoagulanteModerada

    Anticoagulants Metolazone, as well as other thiazide-like diuretics, may affect the hypoprothrombinemic response to anticoagulants; dosage adjustments may be necessary. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Dapagliflozinainhibidor de SGLT2Moderada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Dapagliflozina y metforminainhibidor de SGLT2Moderada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • DeflazacortcorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Desipraminaantidepresivo tricíclicoModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with NORPRAMIN. (etiqueta de Desipramina, Advertencias)

  • DesmopresinaModerada

    …Hyponatremia Concomitant administration of DESMODA with other drugs that may increase the risk of water intoxication with hyponatremia, (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, thiazide diuretics, NSAIDs, lamotrigine, sulfonylureas, particularly chlorpropamide, oxybutynin and carbamazepine). (etiqueta de Desmopresina, Interacciones medicamentosas)

  • DesonidacorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • DesvenlafaxinaIRSNModerada

    Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk [see Use in Specific Populations (8.5) and Clinical Pharmacology (12.3) ] . (etiqueta de Desvenlafaxina, Advertencias y precauciones)

  • DexametasonacorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Dexanfetaminaestimulante del SNCModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Dexlansoprazolinhibidor de la bomba de protonesModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etiqueta de Dexlansoprazol, Advertencias y precauciones)

  • Dexmetilfenidatoestimulante del SNCModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • DiclofenacoAINEModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Diclorfenamidainhibidor de la anhidrasa carbónicaModerada

    Drugs that Cause Hypokalemia The risk of hypokalemia is greater with coadministration of KEVEYIS and other drugs that can cause hypokalemia (e.g., loop diuretics, thiazide diuretics, laxatives, antifungals, penicillins, and theophylline) [see Warnings and Precautions (5.3) ] . (etiqueta de Diclorfenamida, Interacciones medicamentosas)

  • DiflunisalAINEModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Digoxinaglucósido digitálicoModerada

    Digitalis Glycosides Diuretic-induced hypokalemia can increase the sensitivity of the myocardium to digitalis. (etiqueta de Metolazona, Interacciones medicamentosas)

  • DobutaminasimpaticomiméticoModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Doxercalciferolanálogo de la vitamina DModerada

    Risk may be increased when used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (etiqueta de Doxercalciferol, Advertencias y precauciones)

  • Drospirenona y etinilestradiolanticonceptivo oralModerada

    Medications that may increase serum potassium concentration include ACE inhibitors, angiotensin-II receptor antagonists, potassium-sparing diuretics, potassium supplementation, heparin, aldosterone antagonists, and NSAIDS. (etiqueta de Drospirenona y etinilestradiol, Advertencias y precauciones)

  • DroxidopasimpaticomiméticoModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Dulaglutidaagonista del receptor de GLP-1Moderada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • DuloxetinaIRSNModerada

    The risk of BP decreases may be greater in patients taking concomitant medications that induce orthostatic hypotension (such as antihypertensives) or are potent CYP1A2 inhibitors [see Drug Interactions ( 7.1 )] and in patients taking duloxetine delayed-release capsules at doses above 60 mg daily. (etiqueta de Duloxetina, Advertencias y precauciones)

  • EdoxabánanticoagulanteModerada

    Anticoagulants Metolazone, as well as other thiazide-like diuretics, may affect the hypoprothrombinemic response to anticoagulants; dosage adjustments may be necessary. (etiqueta de Metolazona, Interacciones medicamentosas)

  • EfedrinasimpaticomiméticoModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • EluxadolinaopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Empagliflozinainhibidor de SGLT2Moderada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Empagliflozina y metforminainhibidor de SGLT2Moderada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • EnoxaparinaanticoagulanteModerada

    Anticoagulants Metolazone, as well as other thiazide-like diuretics, may affect the hypoprothrombinemic response to anticoagulants; dosage adjustments may be necessary. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Following initiation and titration of Epogen, approximately 25% of patients on dialysis required initiation of or increases in antihypertensive therapy; hypertensive encephalopathy and seizures have been reported in patients with CKD receiving Epogen. (etiqueta de Epoetina alfa, Advertencias y precauciones)

  • Epoprostenolanálogo de prostaglandinaModerada

    Additional reductions in blood pressure may occur when VELETRI is administered with diuretics, antihypertensive agents, or other vasodilators. (etiqueta de Epoprostenol, Interacciones medicamentosas)

  • Ergotamina y cafeínaalcaloide ergóticoModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • EscitalopramISRSModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (etiqueta de Escitalopram, Advertencias y precauciones)

  • EsmololbetabloqueanteModerada

    Antihypertensive agents clonidine, guanfacine, or moxonidine: Beta blockers also increase the risk of clonidine-, guanfacine-, or moxonidine-withdrawal rebound hypertension. (etiqueta de Esmolol, Interacciones medicamentosas)

  • Esomeprazolinhibidor de la bomba de protonesModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etiqueta de Esomeprazol, Advertencias y precauciones)

  • EtodolacoAINEModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Exenatidaagonista del receptor de GLP-1Moderada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Fendimetrazinaestimulante del SNCModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Fenelzinainhibidor de la MAOModerada

    …hydrochloride desipramine hydrochloride imipramine hydrochloride doxepin carbamazepine cyclobenzaprine HCl amoxapine maprotiline HCl trimipramine maleate protriptyline HCl mirtazapine Phenelzine sulfate should be used with caution in combination with antihypertensive drugs, including thiazide diuretics and β-blockers, since exaggerated hypotensive effects may result. (etiqueta de Fenelzina, Advertencias)

  • FenilefrinadescongestionanteModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • FenobarbitalbarbitúricoModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • FenoprofenoAINEModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • FentaniloopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Fenterminaestimulante del SNCModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Fentermina y topiramatoestimulante del SNCModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Fluconazolantifúngico azólicoModerada

    An effect of this magnitude should not necessitate a change in the fluconazole dose regimen in subjects receiving concomitant diuretics. (etiqueta de Fluconazol, Interacciones medicamentosas)

  • FludrocortisonacorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • FlunisolidacorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • FluocinonidacorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • FluoxetinaISRSModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (etiqueta de Fluoxetina, Advertencias y precauciones)

  • FlurbiprofenoAINEModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • FluticasonacorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Fluticasona y salmeterolcorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • FluvoxaminaISRSModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (etiqueta de Fluvoxamina, Advertencias y precauciones)

  • FondaparinuxanticoagulanteModerada

    Anticoagulants Metolazone, as well as other thiazide-like diuretics, may affect the hypoprothrombinemic response to anticoagulants; dosage adjustments may be necessary. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Formoterolagonista beta-adrenérgicoModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • FoscarnetantiviralModerada

    When diuretics are indicated, thiazides are recommended over loop diuretics because the latter inhibit renal tubular secretion, and may impair elimination of FOSCAVIR, potentially leading to toxicity. (etiqueta de Foscarnet, Interacciones medicamentosas)

  • GlibenclamidasulfonilureaModerada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Glibenclamida y metforminasulfonilureaModerada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • GlimepiridasulfonilureaModerada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • GlipizidasulfonilureaModerada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Glipizida y metforminasulfonilureaModerada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • HalobetasolcorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • HaloperidolantipsicóticoModerada

    Caution is advised when haloperidol decanoate is used in combination with drugs known to cause electrolyte imbalance (e.g., diuretics or corticosteroids) because hypokalemia, hypomagnesemia, and hypocalcemia are risk factors for QT prolongation. (etiqueta de Haloperidol, Interacciones medicamentosas)

  • HeparinaanticoagulanteModerada

    Anticoagulants Metolazone, as well as other thiazide-like diuretics, may affect the hypoprothrombinemic response to anticoagulants; dosage adjustments may be necessary. (etiqueta de Metolazona, Interacciones medicamentosas)

  • HidrocodonaopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • HidrocortisonacorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • HidromorfonaopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • IbuprofenoAINEModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • IloperidonaantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etiqueta de Iloperidona, Advertencias y precauciones)

  • Imipraminaantidepresivo tricíclicoModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with imipramine hydrochloride tablets. (etiqueta de Imipramina, Advertencias)

  • IndometacinaAINEModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Insulina aspartainsulinaModerada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Insulina degludecinsulinaModerada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Insulina detemirinsulinaModerada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Insulina glarginainsulinaModerada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Insulina lisproinsulinaModerada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Ipratropio y salbutamolanticolinérgicoModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Isoprenalina (isoproterenol)agonista beta-adrenérgicoModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Ketoconazolantifúngico azólicoModerada

    Diuretics eplerenone The potential increase in plasma concentrations of eplerenone when coadministered with ketoconazole tablets may increase the risk of hyperkalemia and hypotension. (etiqueta de Ketoconazol, Interacciones medicamentosas)

  • KetoprofenoAINEModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • KetorolacoAINEModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Lansoprazolinhibidor de la bomba de protonesModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etiqueta de Lansoprazol, Advertencias y precauciones)

  • LevomilnacipránIRSNModerada

    Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk. (etiqueta de Levomilnaciprán, Advertencias y precauciones)

  • LevorfanolopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Levosalbutamolagonista beta-adrenérgicoModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Lidocaína y adrenalinaanestésico localModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Linagliptinainhibidor de la DPP-4Moderada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Linagliptina y metforminainhibidor de la DPP-4Moderada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • LinezolidantibióticoModerada

    Monitor serum sodium levels regularly in the elderly, in patients taking diuretics, and in other patients at risk of hyponatremia and/or SIADH while taking Linezolid injection. (etiqueta de Linezolid, Advertencias y precauciones)

  • Liraglutidaagonista del receptor de GLP-1Moderada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Lisdexanfetaminaestimulante del SNCModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Litiofármaco serotoninérgicoModerada

    Concomitant Therapy Lithium In general, diuretics should not be given concomitantly with lithium because they reduce its renal clearance and add a high risk of lithium toxicity. (etiqueta de Metolazona, Advertencias)

  • LumateperonaantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive drugs), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and patients… (etiqueta de Lumateperona, Advertencias y precauciones)

  • LurasidonaantipsicóticoModerada

    Patients at increased risk of these adverse reactions or at increased risk of developing complications from hypotension include those with dehydration, hypovolemia, treatment with antihypertensive medication, history of cardiovascular disease (e.g., heart failure, myocardial infarction, ischemia, or conduction abnormalities), history of cerebrovascular disease,… (etiqueta de Lurasidona, Advertencias y precauciones)

  • MeloxicamAINEModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • MesalazinasalicilatoModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • MetadonaopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Metanfetaminaestimulante del SNCModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • MetenaminaantibióticoModerada

    Methenamine Efficacy may be decreased due to urinary alkalizing effect of metolazone. (etiqueta de Metolazona, Interacciones medicamentosas)

  • MetforminabiguanidaModerada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Metilfenidatoestimulante del SNCModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • MetilprednisolonacorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • MetohexitalbarbitúricoModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Midodrinaagonista alfa-adrenérgicoModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • MiglitolantidiabéticoModerada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • MilnacipránIRSNModerada

    Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Geriatric Use ( 8.5 )] . (etiqueta de Milnaciprán, Advertencias y precauciones)

  • Mirabegrónagonista beta-adrenérgicoModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • MirtazapinaantidepresivoModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia [see Use in Specific Populations (8.5) ] . (etiqueta de Mirtazapina, Advertencias y precauciones)

  • Modafiniloestimulante del SNCModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • MometasonacorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • MorfinaopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • NabumetonaAINEModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • NalbufinaopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • NaproxenoAINEModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • NateglinidameglitinidaModerada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • NiacinaModerada

    Antihypertensive Therapy Niacin may potentiate the effects of ganglionic blocking agents and vasoactive drugs resulting in postural hypotension. (etiqueta de Niacina, Interacciones medicamentosas)

  • Nimodipinobloqueador de los canales de calcio dihidropiridínicoModerada

    Blood Pressure Lowering Drugs Nimodipine may increase the blood pressure lowering effect of concomitantly administered anti-hypertensives such as diuretics, beta-blockers, ACE inhibitors, angiotensin receptor blockers, other calcium channel blockers, α-adrenergic blockers, PDE5 inhibitors, and α-methyldopa. (etiqueta de Nimodipino, Interacciones medicamentosas)

  • NitroglicerinanitratoModerada

    Antihypertensives: Possible additive hypotensive effects. (etiqueta de Nitroglicerina, Interacciones medicamentosas)

  • OlanzapinaantipsicóticoModerada

    …of myocardial infarction or ischemia, heart failure, or conduction abnormalities), cerebrovascular disease, and conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications) where the occurrence of syncope, or hypotension and/or bradycardia might put the patient at increased medical risk. (etiqueta de Olanzapina, Advertencias y precauciones)

  • Olanzapina y fluoxetinaantipsicóticoModerada

    …and fluoxetine capsules should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemia, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions that would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (etiqueta de Olanzapina y fluoxetina, Advertencias y precauciones)

  • OliceridinaopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Olopatadina y mometasonaantihistamínicoModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Omeprazolinhibidor de la bomba de protonesModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (etiqueta de Omeprazol, Advertencias y precauciones)

  • Omeprazol y bicarbonato de sodioinhibidor de la bomba de protonesModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (etiqueta de Omeprazol y bicarbonato de sodio, Advertencias y precauciones)

  • Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • OxaprozinaAINEModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • OxicodonaopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • OximetazolinadescongestionanteModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • OximorfonaopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • PaliperidonaantipsicóticoModerada

    Use ERZOFRI with caution in patients with known cardiovascular disease (e.g., heart failure, history of myocardial infarction or ischemia, conduction abnormalities), cerebrovascular disease, or conditions that predispose the patient to hypotension (e.g., dehydration, hypovolemia, and treatment with antihypertensive medications). (etiqueta de Paliperidona, Advertencias y precauciones)

  • Pantoprazolinhibidor de la bomba de protonesModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (etiqueta de Pantoprazol, Advertencias y precauciones)

  • Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Paracetamol y codeínaopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Paricalcitolanálogo de la vitamina DModerada

    The risk may be increased when Paricalcitol Injection is used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (etiqueta de Paricalcitol, Advertencias y precauciones)

  • ParoxetinaISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SNRIs and SSRIs. [see Use in Specific Populations ( 8.5 )]. (etiqueta de Paroxetina, Advertencias y precauciones)

  • PazopanibModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (etiqueta de Pazopanib, Advertencias y precauciones)

  • Pentazocina y naloxonaopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • PentoxifilinametilxantinaModerada

    Small decreases in blood pressure have been observed in some patients treated with pentoxifylline extended-release tablets; periodic systemic blood pressure monitoring is recommended for patients receiving concomitant antihypertensive therapy. (etiqueta de Pentoxifilina, Interacciones medicamentosas)

  • Petidina (meperidina)opioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • PioglitazonatiazolidinedionaModerada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Pioglitazona y glimepiridatiazolidinedionaModerada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Pioglitazona y metforminatiazolidinedionaModerada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • PiroxicamAINEModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • PrednisolonacorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • PrednisonacorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Prilocaína y adrenalinaanestésico localModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • PrimidonaanticonvulsivoModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • ProclorperazinaantipsicóticoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Prometazina y codeínaopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • PseudoefedrinadescongestionanteModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • QuetiapinaantipsicóticoModerada

    Quetiapine should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (etiqueta de Quetiapina, Advertencias y precauciones)

  • QuinidinaantiarrítmicoModerada

    Drugs that alkalinize the urine ( carbonic-anhydrase inhibitors, sodium bicarbonate, thiazide diuretics ) reduce renal elimination of quinidine. (etiqueta de Quinidina, Interacciones medicamentosas)

  • Rabeprazolinhibidor de la bomba de protonesModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (etiqueta de Rabeprazol, Advertencias y precauciones)

  • RemifentaniloopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • RepaglinidameglitinidaModerada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • RiociguatvasodilatadorModerada

    Consider the potential for symptomatic hypotension or ischemia in patients with hypovolemia, severe left ventricular outflow obstruction, resting hypotension, autonomic dysfunction, or concomitant treatment with antihypertensives or strong CYP and P-gp/BCRP inhibitors [see Drug Interactions (7.2) and Clinical Pharmacology (12.3) ] . (etiqueta de Riociguat, Advertencias y precauciones)

  • RisperidonaantipsicóticoModerada

    Clinically significant hypotension has been observed with concomitant use of oral RISPERDAL and antihypertensive medication. (etiqueta de Risperidona, Advertencias y precauciones)

  • RivaroxabánanticoagulanteModerada

    Anticoagulants Metolazone, as well as other thiazide-like diuretics, may affect the hypoprothrombinemic response to anticoagulants; dosage adjustments may be necessary. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Salbutamolagonista beta-adrenérgicoModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Salmeterolagonista beta-adrenérgicoModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • SalsalatoAINEModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Saxagliptinainhibidor de la DPP-4Moderada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Saxagliptina y metforminainhibidor de la DPP-4Moderada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Semaglutidaagonista del receptor de GLP-1Moderada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • SertralinaISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (etiqueta de Sertralina, Advertencias y precauciones)

  • Sildenafiloinhibidor de la PDE5Moderada

    Caution is advised when SILDENAFIL ORAL FILM is co-administered with alpha-blockers or antihypertensives. (etiqueta de Sildenafilo, Advertencias y precauciones)

  • SilodosinaalfabloqueanteModerada

    However, patients in the Phase 3 clinical studies taking concomitant antihypertensive medications with silodosin capsules did not experience a significant increase in the incidence of syncope, dizziness, or orthostasis. (etiqueta de Silodosina, Advertencias y precauciones)

  • Sitagliptinainhibidor de la DPP-4Moderada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Sitagliptina y metforminainhibidor de la DPP-4Moderada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • Solriamfetolestimulante del SNCModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • SorafenibModerada

    Consider temporary or permanent discontinuation for severe or persistent hypertension despite antihypertensive therapy. (etiqueta de Sorafenib, Advertencias y precauciones)

  • SotalolbetabloqueanteModerada

    Special attention should be given to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or patients receiving concomitant diuretic drugs. (etiqueta de Sotalol, Advertencias y precauciones)

  • Subsalicilato de bismutosalicilatoModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Drug Interactions In elderly patients concurrently receiving certain diuretics, primarily thiazides, an increased incidence of thrombocytopenia with purpura has been reported. (etiqueta de Sulfametoxazol y trimetoprima, Interacciones medicamentosas)

  • SulfasalazinasulfonamidaModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • SulindacoAINEModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Sumatriptán y naproxenotriptánModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • SunitinibModerada

    Initiate and/or adjust antihypertensive therapy as appropriate. (etiqueta de Sunitinib, Advertencias y precauciones)

  • Suxametonio (succinilcolina)bloqueador neuromuscularModerada

    Prolonged Neuromuscular Block in Patients with Hypokalemia or Hypocalcemia Neuromuscular blockade may be prolonged in patients with hypokalemia (e.g., after severe vomiting, diarrhea, digitalisation and diuretic therapy) or hypocalcemia (e.g., after massive transfusions). (etiqueta de Suxametonio (succinilcolina), Advertencias y precauciones)

  • TacrolimusinmunosupresorModerada

    • Hypertension: May require antihypertensive therapy; monitor relevant drug interactions. (etiqueta de Tacrolimus, Advertencias y precauciones)

  • TapentadolopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Terbutalinaagonista beta-adrenérgicoModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • TestosteronaandrógenoModerada

    In patients with hypertension on antihypertensive therapy, TLANDO increased the mean systolic/diastolic BP by 4.8/1.6 mm Hg from baseline. [see Adverse Reactions ( 6.1 )] . (etiqueta de Testosterona, Advertencias y precauciones)

  • Tirzepatidaagonista del receptor de GLP-1Moderada

    Insulin And Oral Antidiabetic Agents See Glucose Tolerance under PRECAUTIONS , General . (etiqueta de Metolazona, Interacciones medicamentosas)

  • TobramicinaaminoglucósidoModerada

    Some diuretics can enhance aminoglycoside toxicity by altering antibiotic concentrations in serum and tissue. (etiqueta de Tobramicina, Interacciones medicamentosas)

  • TolmetinaAINEModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (etiqueta de Metolazona, Interacciones medicamentosas)

  • TolvaptánModerada

    Co-administration of diuretics also increases the risk of too rapid correction of serum sodium and such patients should undergo close monitoring of serum sodium. (etiqueta de Tolvaptán, Advertencias y precauciones)

  • Toremifenomodulador selectivo de los receptores de estrógenosModerada

    Drugs that decrease renal calcium excretion, e.g., thiazide diuretics, may increase the risk of hypercalcemia in patients receiving FARESTON. (etiqueta de Toremifeno, Interacciones medicamentosas)

  • TramadolopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Tramadol y paracetamolopioideModerada

    Alcohol, Barbiturates, And Narcotics The hypotensive effects of these drugs may be potentiated by the volume contraction that may be associated with metolazone therapy. (etiqueta de Metolazona, Interacciones medicamentosas)

  • TrazodonaantidepresivoModerada

    Concomitant use with an antihypertensive may require a reduction in the dose of the antihypertensive drug. (etiqueta de Trazodona, Advertencias y precauciones)

  • TriamcinolonacorticosteroideModerada

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etiqueta de Metolazona, Interacciones medicamentosas)

  • TrifluoperazinaantipsicóticoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Trifluoperazina, Precauciones)

  • Umeclidinio y vilanterolanticolinérgicoModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Vardenafiloinhibidor de la PDE5Moderada

    Vardenafil hydrochloride tablets can potentiate the hypotensive effects of nitrates, alpha- blockers, and antihypertensives. (etiqueta de Vardenafilo, Interacciones medicamentosas)

  • VenlafaxinaIRSNModerada

    Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (etiqueta de Venlafaxina, Advertencias y precauciones)

  • Vibegrónagonista beta-adrenérgicoModerada

    Sympathomimetics Metolazone may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. (etiqueta de Metolazona, Interacciones medicamentosas)

  • VilazodonaISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs and SNRIs [see Use in Specific Populations ( 8.5 )] . (etiqueta de Vilazodona, Advertencias y precauciones)

  • Vitamina DVitaminas y mineralesModerada

    Los diuréticos tiazídicos reducen la excreción de calcio; combinados con suplementos de vitamina D y de calcio, esto puede llevar a hipercalcemia, sobre todo en adultos mayores. (NIH Office of Dietary Supplements, Vitamin D)

  • VortioxetinaantidepresivoModerada

    Also, patients taking diuretics or who are otherwise volume-depleted can be at greater risk. (etiqueta de Vortioxetina, Advertencias y precauciones)

  • WarfarinaanticoagulanteModerada

    Anticoagulants Metolazone, as well as other thiazide-like diuretics, may affect the hypoprothrombinemic response to anticoagulants; dosage adjustments may be necessary. (etiqueta de Metolazona, Interacciones medicamentosas)

  • Concurrent use with potassium-containing medications, potassium-sparing diuretics and angiotensin-converting enzyme inhibitors (ACE inhibitors) may result in hyperkalemia and cardiac arrhythmias or cardiac arrest. (etiqueta de Yoduro de potasio, Interacciones medicamentosas)

  • ZiprasidonaantipsicóticoModerada

    Hypokalemia may result from diuretic therapy, diarrhea, and other causes. (etiqueta de Ziprasidona, Advertencias y precauciones)

Menciones leves (32)

  • Patients required intervention with a diuretic, fluid management, or, in some cases, hospitalization for decompensating heart failure. (etiqueta de Ambrisentán, Advertencias y precauciones)

  • Bosentáninductor de CYP3A4Leve

    Patients required intervention with a diuretic, fluid management, or hospitalization for decompensating heart failure. (etiqueta de Bosentán, Advertencias y precauciones)

  • Brinzolamidainhibidor de la anhidrasa carbónicaLeve

    Cross-Allergy Cross-allergy may occur when metolazone tablets, USP, are given to patients known to be allergic to sulfonamide-derived drugs, thiazides, or quinethazone. (etiqueta de Metolazona, Advertencias)

  • CalcioVitaminas y mineralesLeve

    Los diuréticos tiazídicos reducen la excreción de calcio, por lo que una ingesta alta de calcio puede elevar el calcio en sangre. (NIH Office of Dietary Supplements, Calcium)

  • Acthar Gel may accentuate the electrolyte loss associated with diuretic therapy. (etiqueta de Corticotropina, Interacciones medicamentosas)

  • Fluid retention events were typically managed by supportive care measures that may include diuretics or short courses of steroids. (etiqueta de Dasatinib, Advertencias y precauciones)

  • Desogestrel y etinilestradiolanticonceptivo oralLeve

    If other contraceptive methods are not suitable, hormonal contraceptive therapy may continue combined with antihypertensive therapy. (etiqueta de Desogestrel y etinilestradiol, Advertencias)

  • Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (etiqueta de Docetaxel, Advertencias y precauciones)

  • Dorzolamidainhibidor de la anhidrasa carbónicaLeve

    Cross-Allergy Cross-allergy may occur when metolazone tablets, USP, are given to patients known to be allergic to sulfonamide-derived drugs, thiazides, or quinethazone. (etiqueta de Metolazona, Advertencias)

  • Dorzolamida y timololinhibidor de la anhidrasa carbónicaLeve

    Cross-Allergy Cross-allergy may occur when metolazone tablets, USP, are given to patients known to be allergic to sulfonamide-derived drugs, thiazides, or quinethazone. (etiqueta de Metolazona, Advertencias)

  • DronedaronaantiarrítmicoLeve

    Hypokalemia and Hypomagnesemia with Potassium-Depleting Diuretics Hypokalemia or hypomagnesemia may occur with concomitant administration of potassium-depleting diuretics. (etiqueta de Dronedarona, Advertencias y precauciones)

  • In addition to discontinuation of the drug, diuretic therapy may be required. (etiqueta de Estrógenos esterificados y metiltestosterona, Advertencias)

  • Finasteridainhibidor de la 5-alfa reductasaLeve

    …clinical studies with acetaminophen, acetylsalicylic acid, α-blockers, angiotensin-converting enzyme (ACE) inhibitors, analgesics, anti-convulsants, beta-adrenergic blocking agents, diuretics, calcium channel blockers, cardiac nitrates, HMG-CoA reductase inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, H 2 antagonists and quinolone anti-infectives… (etiqueta de Finasterida, Interacciones medicamentosas)

  • FlecainidaantiarrítmicoLeve

    Flecainide acetate has been used in a large number of patients receiving diuretics without apparent interaction. (etiqueta de Flecainida, Interacciones medicamentosas)

  • Drugs that may cause hypercalcemia: Vitamin D, vitamin A, thiazide diuretics, estrogen, calcipotriene and teriparatide administration may cause hypercalcemia. (etiqueta de Gluconato de calcio, Interacciones medicamentosas)

  • ACE Inhibitors FIRAZYR is a bradykinin B2 receptor antagonist and thereby has the potential to have a pharmacodynamic interaction with ACE inhibitors where FIRAZYR may attenuate the antihypertensive effect of ACE inhibitors. (etiqueta de Icatibant, Interacciones medicamentosas)

  • Imatinibinhibidor de CYP3A4Leve

    Weigh patients regularly and manage unexpected rapid weight gain by drug interruption and diuretics. (etiqueta de Imatinib, Advertencias y precauciones)

  • Postmarketing cases of edema and fluid retention occurring within weeks of starting OPSUMIT, some requiring intervention with a diuretic or hospitalization for decompensated heart failure, have been reported [see Adverse Reactions (6.2) ] . (etiqueta de Macitentán, Advertencias y precauciones)

  • MagnesioVitaminas y mineralesLeve

    El uso a largo plazo de diuréticos de asa y diuréticos tiazídicos aumenta la pérdida de magnesio por la orina. (NIH Office of Dietary Supplements, Magnesium)

  • Metazolamidainhibidor de la anhidrasa carbónicaLeve

    Cross-Allergy Cross-allergy may occur when metolazone tablets, USP, are given to patients known to be allergic to sulfonamide-derived drugs, thiazides, or quinethazone. (etiqueta de Metolazona, Advertencias)

  • MetiltestosteronaandrógenoLeve

    In addition to discontinuation of the drug, diuretic therapy may be required. (etiqueta de Metiltestosterona, Advertencias)

  • MexiletinaantiarrítmicoLeve

    In a large compassionate use program mexiletine has been used concurrently with commonly employed antianginal, antihypertensive, and anticoagulant drugs without observed interactions. (etiqueta de Mexiletina, Interacciones medicamentosas)

  • Nortriptilinaantidepresivo tricíclicoLeve

    The antihypertensive action of guanethidine and similar agents may be blocked. (etiqueta de Nortriptilina, Advertencias)

  • Penicilina Gantibiótico del grupo de las penicilinasLeve

    These drugs include: aspirin, phenylbutazone, sulfonamides, indomethacin, thiazide diuretics, furosemide and ethacrynic acid. (etiqueta de Penicilina G, Interacciones medicamentosas)

  • Piperacilina y tazobactamantibiótico del grupo de las penicilinasLeve

    Periodic electrolyte determinations should be performed in patients with low potassium reserves, and the possibility of hypokalemia should be kept in mind with patients who have potentially low potassium reserves and who are receiving cytotoxic therapy or diuretics. (etiqueta de Piperacilina y tazobactam, Advertencias y precauciones)

  • PotasioVitaminas y mineralesLeve

    Los diuréticos de asa y los diuréticos tiazídicos aumentan la pérdida de potasio; a veces se prescribe un suplemento junto con ellos. (NIH Office of Dietary Supplements, Potassium)

  • Protriptilinaantidepresivo tricíclicoLeve

    Protriptyline may block the antihypertensive effect of guanethidine or similarly acting compounds. (etiqueta de Protriptilina, Advertencias)

  • SulfadiazinasulfonamidaLeve

    Cross-Allergy Cross-allergy may occur when metolazone tablets, USP, are given to patients known to be allergic to sulfonamide-derived drugs, thiazides, or quinethazone. (etiqueta de Metolazona, Advertencias)

  • Sulfadiazina de platasulfonamidaLeve

    Cross-Allergy Cross-allergy may occur when metolazone tablets, USP, are given to patients known to be allergic to sulfonamide-derived drugs, thiazides, or quinethazone. (etiqueta de Metolazona, Advertencias)

  • TerbinafinaantifúngicoLeve

    There is no information available from adequate drug-drug interaction studies with the following classes of drugs: oral contraceptives, hormone replacement therapies, hypoglycemics, phenytoins, thiazide diuretics, and calcium channel blockers. (etiqueta de Terbinafina, Interacciones medicamentosas)

  • ZincVitaminas y mineralesLeve

    Los diuréticos tiazídicos aumentan la pérdida de zinc por la orina con el uso a largo plazo. (NIH Office of Dietary Supplements, Zinc)

  • ZonisamidaanticonvulsivoLeve

    Cross-Allergy Cross-allergy may occur when metolazone tablets, USP, are given to patients known to be allergic to sulfonamide-derived drugs, thiazides, or quinethazone. (etiqueta de Metolazona, Advertencias)

Sin interacción significativa según la etiqueta (2)

  • PamidronatobisfosfonatoSin interacción

    Loop Diuretics Concomitant administration of a loop diuretic had no effect on the calcium-lowering action of pamidronate disodium. (etiqueta de Pamidronato, Interacciones medicamentosas)

  • Ropinirolagonista de la dopaminaSin interacción

    Commonly Administered Drugs: Population analysis showed that commonly administered drugs (e.g., selegiline, amantadine, tricyclic antidepressants, benzodiazepines, ibuprofen, thiazides, antihistamines, anticholinergics) did not affect the clearance of ropinirole. (etiqueta de Ropinirol, Interacciones medicamentosas)

Compruebe Metolazona frente a todo lo que toma. Añada su lista completa; todos los pares se comprueban a la vez.

Abrir en el verificador

No es un consejo médico. La gravedad refleja la redacción de la etiqueta, no sus circunstancias. Una señal «grave» puede ser algo habitual bajo supervisión y una «leve» puede ser importante a dosis altas. Consulte a un farmacéutico.