Interacciones de Metoprolol e hidroclorotiazida

Anuria Hypersensitivity to metoprolol tartrate or hydrochlorothiazide or to other sulfonamide- derived drugs. (etiqueta de Metoprolol e hidroclorotiazida, Contraindicaciones)

CONTRAINDICATIONS All diuretics, including ethacrynic acid, are contraindicated in anuria. (etiqueta de Ácido etacrínico, Contraindicaciones)

Hyperkalemia occurs commonly (about 10%) when amiloride is used without a kaliuretic diuretic. (etiqueta de Amilorida, Advertencia en recuadro)

Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (etiqueta de Benazepril e hidroclorotiazida, Contraindicaciones)

Sodium bicarbonate injection is contraindicated in patients who are losing chloride by vomiting or from continuous gastrointestinal suction and in patients receiving diuretics known to produce a hypochloremic alkalosis. (etiqueta de Bicarbonato de sodio, Contraindicaciones)

Anuria Hypersensitivity to metoprolol tartrate or hydrochlorothiazide or to other sulfonamide- derived drugs. (etiqueta de Metoprolol e hidroclorotiazida, Contraindicaciones)

WARNING Bumetanide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. (etiqueta de Bumetanida, Advertencia en recuadro)

Potassium-Sparing Diuretics Cyclosporine should not be used with potassium-sparing diuretics because hyperkalemia can occur. (etiqueta de Ciclosporina, Interacciones medicamentosas)

The following drug interactions may occur with potassium citrate: Potassium-sparing diuretics: concomitant administration should be avoided since the simultaneous administration of these agents can produce severe hyperkalemia (7.1) (etiqueta de Citrato de potasio, Interacciones medicamentosas)

…concomitantly with Ferric Citrate Tablets Amlodipine Aspirin Atorvastatin Calcitriol Clopidogrel Digoxin Diltiazem Doxercalciferol Enalapril Fluvastatin Glimepiride Levofloxacin Losartan Metoprolol Pravastatin Propranolol Sitagliptin Warfarin Oral drugs that have to be separated from Ferric Citrate Tablets and meals Dosing Recommendations Doxycycline Take at least 1… (etiqueta de Citrato férrico, Interacciones medicamentosas)

Use CLOZARIL cautiously in patients with cardiovascular or cerebrovascular disease or conditions predisposing to hypotension (e.g., dehydration, use of antihypertensive medications) [see Dosage and Administration ( 2.2 , 2.6 ), Warnings and Precautions ( 5.2 )]. (etiqueta de Clozapina, Advertencia en recuadro)

Because the use of diuretics can accentuate the diminished intravascular volume, avoid diuretics except in the late phase of resolution. (etiqueta de Coriogonadotropina alfa, Advertencias)

CONTRAINDICATIONS PROGLYCEM is contraindicated in patients with: Functional hypoglycemia Hypersensitivity to diazoxide, any of the excipients in PROGLYCEM, or other thiazides (etiqueta de Diazóxido, Contraindicaciones)

Anuria Hypersensitivity to metoprolol tartrate or hydrochlorothiazide or to other sulfonamide- derived drugs. (etiqueta de Metoprolol e hidroclorotiazida, Contraindicaciones)

The concomitant use of hydrochlorothiazide (alone or in combinations such as with triamterene) with dofetilide is contraindicated (see PRECAUTIONS, Drug-Drug Interactions ) because this has been shown to significantly increase dofetilide plasma concentrations and QT interval prolongation. (etiqueta de Dofetilida, Contraindicaciones)

Anuria Hypersensitivity to metoprolol tartrate or hydrochlorothiazide or to other sulfonamide- derived drugs. (etiqueta de Metoprolol e hidroclorotiazida, Contraindicaciones)

Anuria Hypersensitivity to metoprolol tartrate or hydrochlorothiazide or to other sulfonamide- derived drugs. (etiqueta de Metoprolol e hidroclorotiazida, Contraindicaciones)

Droperidol should be administered with extreme caution to patients who may be at risk for development of prolonged QT syndrome (e.g., congestive heart failure, bradycardia, use of a diuretic, cardiac hypertrophy, hypokalemia, hypomagnesemia, or administration of other drugs known to increase the QT interval). (etiqueta de Droperidol, Advertencia en recuadro)

…sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include those with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (etiqueta de Enalaprilato, Advertencias)

…• serum creatinine > 2.0 mg/dL in males or >1.8 mg/dL in females, • creatinine clearance < 50 mL/min, or • concomitant administration of potassium supplements or potassium-sparing diuretics (e.g., amiloride, spironolactone, or triamterene) [see Warnings and Precautions (5.1) , Adverse Reactions (6.2) , Drug Interactions (7) , and Clinical Pharmacology (12.3)… (etiqueta de Eplerenona, Contraindicaciones)

…of active abnormal bleeding within the previous 30 days Severe hypertension (systolic blood pressure >200 mm Hg or diastolic blood pressure >110 mm Hg) not adequately controlled on antihypertensive therapy Major surgery within the preceding 6 weeks History of stroke within 30 days or any history of hemorrhagic stroke Current or planned administration of another… (etiqueta de Eptifibatida, Contraindicaciones)

Concomitant negative chronotropic therapy such as digoxin or beta-blockers may lower the risk of this complication. (etiqueta de Flecainida, Advertencia en recuadro)

Because the use of diuretics can accentuate the diminished intravascular volume, diuretics should be avoided except in the late phase of resolution as described below. (etiqueta de Folitropina, Advertencias y precauciones)

The concurrent use of gentamicin with potent diuretics, such as ethacrynic acid or furosemide, should be avoided, since certain diuretics by themselves may cause ototoxicity. (etiqueta de Gentamicina, Advertencia en recuadro)

Avoid diuretics or laxatives in patients with diarrhea. (etiqueta de Irinotecán, Advertencias y precauciones)

Diuretics Eplerenone Contraindicated during and 2 weeks after TOLSURA treatment. (etiqueta de Itraconazol, Interacciones medicamentosas)

Anuria Hypersensitivity to metoprolol tartrate or hydrochlorothiazide or to other sulfonamide- derived drugs. (etiqueta de Metoprolol e hidroclorotiazida, Contraindicaciones)

In addition, life-threatening arrhythmias may occur during anesthesia and surgery, and may require treatment with a beta-blocker or lidocaine. (etiqueta de Metirosina, Advertencias)

Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

Minoxidil should be reserved for hypertensive patients who do not respond adequately to maximum therapeutic doses of a diuretic and two other antihypertensive agents. (etiqueta de Minoxidil, Advertencia en recuadro)

Hypotensive Agents Do not use BYSTOLIC with other β-blockers. (etiqueta de Nebivolol, Interacciones medicamentosas)

The concurrent use of neomycin with potent diuretics such as ethacrynic acid or furosemide should be avoided, since certain diuretics by themselves may cause ototoxicity. (etiqueta de Neomicina, Advertencia en recuadro)

Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

…sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include patients with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (etiqueta de Quinapril, Advertencias)

Examples: beta-blockers, clonidine, guanethidine, and reserpine Clopidogrel : Avoid concomitant use; if used concomitantly initiate at 0.5 mg before each meal and limit total daily dose to 4 mg ( 7 ) (etiqueta de Repaglinida, Interacciones medicamentosas)

Concomitant use with metoclopramide, beta-blockers, or cholinomimetic and anticholinergic drugs is not recommended ( 7.1 , 7.2 , 7.3 ) (etiqueta de Rivastigmina, Interacciones medicamentosas)

Anuria Hypersensitivity to metoprolol tartrate or hydrochlorothiazide or to other sulfonamide- derived drugs. (etiqueta de Metoprolol e hidroclorotiazida, Contraindicaciones)

Anuria Hypersensitivity to metoprolol tartrate or hydrochlorothiazide or to other sulfonamide- derived drugs. (etiqueta de Metoprolol e hidroclorotiazida, Contraindicaciones)

Anuria Hypersensitivity to metoprolol tartrate or hydrochlorothiazide or to other sulfonamide- derived drugs. (etiqueta de Metoprolol e hidroclorotiazida, Contraindicaciones)

Anuria Hypersensitivity to metoprolol tartrate or hydrochlorothiazide or to other sulfonamide- derived drugs. (etiqueta de Metoprolol e hidroclorotiazida, Contraindicaciones)

…coadministration of an alpha-blocker and CIALIS for the treatment of BPH has not been adequately studied, and due to the potential vasodilatory effects of combined use resulting in blood pressure lowering, the combination of CIALIS and alpha-blockers is not recommended for the treatment of BPH. [see Dosage and Administration ( 2.7 ), Drug Interactions ( 7.1 ),… (etiqueta de Tadalafilo, Advertencias y precauciones)

…Syndrome (SS) c ] Agents with blood pressure-reducing effects Use with caution d Hypotension e Non-selective H1 receptor antagonists Contraindicated a Increased anticholinergic effects Beta-adrenergic blockers (see also agents or procedures with blood pressure-reducing effects) Use with the caution d More pronounced bradycardia, postural hypotension e Blood glucose-lowering… (etiqueta de Tranilcipromina, Interacciones medicamentosas)

The risk of torsade de pointes is related to the extent of QTc prolongation, concomitant administration of QTc prolonging drugs, a history of torsade de pointes, pre-existing QTc interval prolongation, congestive heart failure, administration of potassium-wasting diuretics, or other conditions that result in hypokalemia or hypomagnesemia. (etiqueta de Trióxido de arsénico, Advertencias y precauciones)

Anuria Hypersensitivity to metoprolol tartrate or hydrochlorothiazide or to other sulfonamide- derived drugs. (etiqueta de Metoprolol e hidroclorotiazida, Contraindicaciones)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Although β-blockers should be avoided in overt cardiac failure, acebutolol can be used with caution in patients with a history of heart failure who are controlled with digitalis and/or diuretics. (etiqueta de Acebutolol, Advertencias)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (etiqueta de Ácido zoledrónico, Advertencias y precauciones)

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly . (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Patients may be unresponsive to the usual doses of epinephrine used to treat allergic reaction. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Postural hypotension/syncope: Care should be taken in patients with symptomatic hypotension or who have had a hypotensive response to other medications or are concomitantly treated with antihypertensive medication or nitrates ( 5.1 ) (etiqueta de Alfuzosina, Advertencias y precauciones)

Risk factors for the development of hyperkalemia include renal insufficiency, diabetes, combination use with ARBs or ACEIs [see Contraindications ( 4 ), Warnings and Precautions ( 5.2 ), and Clinical Studies ( 14.3 )] , NSAIDs, or potassium supplements or potassium sparing diuretics. (etiqueta de Aliskireno, Advertencias y precauciones)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Hypersensitivity reactions to allopurinol tablets may be increased in patients with decreased kidney function receiving thiazide diuretics and allopurinol tablets concurrently. (etiqueta de Alopurinol, Advertencias y precauciones)

Ethacrynic Acid, Furosemide, Urea, or Mannitol Some diuretics can enhance aminoglycoside toxicity by altering aminoglycoside concentrations in serum and tissue. (etiqueta de Amikacina, Interacciones medicamentosas)

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly . (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Digitalis, Clonidine, and Calcium Channel Blockers: Digitalis glycosides, clonidine, diltiazem and verapamil slow atrioventricular conduction and decrease heart rate. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Digitalis, Clonidine, and Calcium Channel Blockers: Digitalis glycosides, clonidine, diltiazem and verapamil slow atrioventricular conduction and decrease heart rate. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Digitalis, Clonidine, and Calcium Channel Blockers: Digitalis glycosides, clonidine, diltiazem and verapamil slow atrioventricular conduction and decrease heart rate. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Digitalis, Clonidine, and Calcium Channel Blockers: Digitalis glycosides, clonidine, diltiazem and verapamil slow atrioventricular conduction and decrease heart rate. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Digitalis, Clonidine, and Calcium Channel Blockers: Digitalis glycosides, clonidine, diltiazem and verapamil slow atrioventricular conduction and decrease heart rate. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

The pressor effects of diethylpropion and those of other drugs may be additive when the drugs are used concomitantly; conversely, diethylpropion may interfere with antihypertensive drugs (i.e., guanethidine, a-methyldopa). (etiqueta de Anfepramona, Interacciones medicamentosas)

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly . (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Antihypertensive Drugs Due to its alpha-adrenergic antagonism, aripiprazole has the potential to enhance the effect of certain antihypertensive agents. (etiqueta de Aripiprazol, Interacciones medicamentosas)

There was also a slightly greater proportion of patients on NUVIGIL requiring new or increased use of antihypertensive medications (2.9%) compared to patients on placebo (1.8%). (etiqueta de Armodafinilo, Advertencias y precauciones)

Patients may be unresponsive to the usual doses of epinephrine used to treat allergic reaction. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medications, patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), and patients… (etiqueta de Asenapina, Advertencias y precauciones)

Because of its relative beta 1 selectivity, however, TENORMIN may be used with caution in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Atenolol, Advertencias)

Because of its relative beta 1 -selectivity, however, atenolol and chlorthalidone may be used with caution in patients with bronchospastic disease who do not respond to or cannot tolerate, other antihypertensive treatment. (etiqueta de Atenolol y clortalidona, Advertencias)

Antihypertensive Drugs Prevention or Management Increase the frequency of monitoring blood pressure and adjust atomoxetine oral solution dosage as clinically appropriate. (etiqueta de Atomoxetina, Interacciones medicamentosas)

• Use of avanafil with alpha-blockers, other antihypertensives, or substantial amounts of alcohol (greater than 3 units) may lead to hypotension ( 2.3 , 5.6 , 5.7 ) (etiqueta de Avanafilo, Advertencias y precauciones)

Hypotension in Volume- or Salt-Depleted Patients In patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment with azilsartan medoxomil. (etiqueta de Azilsartán, Advertencias y precauciones)

Catecholamine-depleting drugs (e.g., MAO inhibitors): Hypotension, bradycardia. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Diuretics Clinical Impact : Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Belladona y opio, Interacciones medicamentosas)

Patients at risk of excessive hypotension include those with the following conditions or characteristics: heart failure with systolic blood pressure below 100 mm Hg, ischemic heart disease, cerebrovascular disease, hyponatremia, high dose diuretic therapy, renal dialysis, or severe volume and/or salt depletion of any etiology. (etiqueta de Benazepril, Advertencias y precauciones)

Amphetamines may decrease the hypotensive effect of antihypertensives. (etiqueta de Benzfetamina, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Because of its relative beta 1 -selectivity, however, BISOPROLOL FUMARATE may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (etiqueta de Bisoprolol, Advertencias)

Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (etiqueta de Bisoprolol e hidroclorotiazida, Advertencias)

Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medication), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etiqueta de Brexpiprazol, Advertencias y precauciones)

Antihypertensives/Cardiac Glycosides Because brimonidine tartrate ophthalmic solution 0.1% and 0.15% may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate ophthalmic solution 0.1% and 0.15% is advised. (etiqueta de Brimonidina, Interacciones medicamentosas)

Antihypertensives/Cardiac Glycosides Because brimonidine tartrate/timolol maleate ophthalmic solution may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate/timolol maleate ophthalmic solution is advised. (etiqueta de Brimonidina y timolol, Interacciones medicamentosas)

Central Nervous System (CNS) depressants Antihistamines have additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, antianxiety agents, etc.). Antihypertensive drugs Sympathomimetic may reduce the effects of antihypertensive drugs. (etiqueta de Bromfeniramina, pseudoefedrina y dextrometorfano, Interacciones medicamentosas)

Use caution in patients taking antihypertensive medications. (etiqueta de Bromocriptina, Advertencias y precauciones)

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly . (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Risk of Hypertension and Bradycardia Due to Drug Interactions Between MARCAINE WITH EPINEPHRINE and Nonselective Beta-Adrenergic Antagonists Administration of MARCAINE WITH EPINEPHRINE (containing a vasoconstrictor) in patients receiving nonselective beta-adrenergic antagonists may cause severe hypertension and bradycardia. (etiqueta de Bupivacaína, Advertencias y precauciones)

Patients may be unresponsive to the usual doses of epinephrine used to treat allergic reaction. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Buprenorfina, Interacciones medicamentosas)

Examples: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Buprenorfina y naloxona, Interacciones medicamentosas)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Butalbital, paracetamol, cafeína y codeína, Interacciones medicamentosas)

Thiazides Thiazides are known to induce hypercalcemia by the reduction of calcium excretion in urine. (etiqueta de Calcitriol, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Symptomatic hypotension is most likely to occur in patients who have been volume and/or salt depleted as a result of prolonged diuretic therapy, dietary salt restriction, dialysis, diarrhea, or vomiting. (etiqueta de Candesartán, Advertencias y precauciones)

Hypotension Excessive hypotension was rarely seen in hypertensive patients but is a possible consequence of captopril use in salt/volume depleted persons (such as those treated vigorously with diuretics), patients with heart failure or those patients undergoing renal dialysis (see PRECAUTIONS : Drug Interactions ). (etiqueta de Captopril, Advertencias)

Elderly patients and patients treated with diuretics are at greater risk of developing hyponatremia. (etiqueta de Carbamazepina, Advertencias y precauciones)

Symptomatic postural hypotension has occurred when carbidopa, given with levodopa or carbidopa-levodopa combination products, was added to the treatment of a patient receiving antihypertensive drugs. (etiqueta de Carbidopa, Interacciones medicamentosas)

Antihypertensive drugs: May cause symptomatic postural hypotension. (etiqueta de Carbidopa y levodopa, Interacciones medicamentosas)

Antihypertensive Agents Symptomatic postural hypotension has occurred when carbidopa/levodopa was added to the treatment of patients receiving antihypertensive drugs. (etiqueta de Carbidopa, levodopa y entacapona, Interacciones medicamentosas)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etiqueta de Cariprazina, Advertencias y precauciones)

If such symptoms occur, diuretics should be increased and the carvedilol dose should not be advanced until clinical stability resumes [see Dosage and Administration (2) ] . (etiqueta de Carvedilol, Advertencias y precauciones)

Diuretics: Nephrotoxicity has been reported with concomitant administration of cephalosporins with potent diuretics such as furosemide. (etiqueta de Cefepima, Interacciones medicamentosas)

Drug Interactions Nephrotoxicity has been reported following concomitant administration of cephalosporins with aminoglycoside antibacterial drugs or potent diuretics such as furosemide. (etiqueta de Ceftazidima, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

DRUG INTERACTIONS Cevimeline should be administered with caution to patients taking beta adrenergic antagonists, because of the possibility of conduction disturbances. (etiqueta de Cevimelina, Interacciones medicamentosas)

…concomitant use of TONMYA with: MAO inhibitors may be life-threatening [see Contraindications (4) ] , Alcohol, barbiturates, and other CNS depressants may increase the risk of adverse reactions associated with these drugs, Tramadol may increase the seizure risk, Guanethidine or other similar acting drugs may block the antihypertensive action of these drugs. (etiqueta de Ciclobenzaprina, Interacciones medicamentosas)

…inhibitors: ACE inhibitors can cause leukopenia. ● Natalizumab ● Paclitaxel: Increased hematotoxicity has been reported when cyclophosphamide was administered after paclitaxel infusion. ● Thiazide diuretics ● Zidovudine Increased cardiotoxicity ● Anthracyclines ● Cytarabine ● Pentostatin ● Radiation therapy of the cardiac region ● Trastuzumab Increased pulmonary toxicity… (etiqueta de Ciclofosfamida, Interacciones medicamentosas)

Increase the dose of diuretics as needed [see Adverse Reactions (6) ] . (etiqueta de Ciclosilicato de sodio y zirconio, Advertencias y precauciones)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Elderly patients, patients taking diuretics, and those who are volume depleted may be at greater risk for developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (etiqueta de Citalopram, Advertencias y precauciones)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Consider use of diuretics and/or albumin. (etiqueta de Clofarabina, Advertencias y precauciones)

Digitalis, Clonidine, and Calcium Channel Blockers: Digitalis glycosides, clonidine, diltiazem and verapamil slow atrioventricular conduction and decrease heart rate. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Clorotiazida, Advertencias)

Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Clorpromazina, Precauciones)

Effect of chlorthalidone on other drugs Chlorthalidone may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Clortalidona, Interacciones medicamentosas)

Drugs That Increase the Risk of Hypercalcemia Increase frequency of monitoring of calcium concentrations in patients taking concomitant Calcium Chloride Injection and other drugs that increase the risk of hypercalcemia (e.g., calcipotriene, estrogen, lithium, parathyroid hormone, teriparatide, thiazide diuretics, Vitamin A, and Vitamin D). (etiqueta de Cloruro de calcio, Interacciones medicamentosas)

Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Codeína, Interacciones medicamentosas)

Cholestyramine and colestipol: Reduced absorption of thiazides. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Cholestyramine and colestipol: Reduced absorption of thiazides. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with NORPRAMIN. (etiqueta de Desipramina, Advertencias)

…Hyponatremia Concomitant administration of DESMODA with other drugs that may increase the risk of water intoxication with hyponatremia, (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, thiazide diuretics, NSAIDs, lamotrigine, sulfonylureas, particularly chlorpropamide, oxybutynin and carbamazepine). (etiqueta de Desmopresina, Interacciones medicamentosas)

Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk [see Use in Specific Populations (8.5) and Clinical Pharmacology (12.3) ] . (etiqueta de Desvenlafaxina, Advertencias y precauciones)

Drug Interactions with Metoprolol Catecholamine Depleting Drugs: The concomitant use of catecholamine-depleting drugs (e.g., reserpine, monoamine oxidase (MAO) inhibitors) with beta adrenergic blockers may have an additive affect and increase the risk of hypotension or bradycardia CYP2D6 Inhibitors: Drugs that are strong inhibitors of CYP2D6 such as quinidine,… (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etiqueta de Dexlansoprazol, Advertencias y precauciones)

• Antihypertensive Drugs: Monitor blood pressure. (etiqueta de Dexmetilfenidato, Interacciones medicamentosas)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Digitalis, Clonidine, and Calcium Channel Blockers: Digitalis glycosides, clonidine, diltiazem and verapamil slow atrioventricular conduction and decrease heart rate. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Beta Blockers Although the results of a clinical study did not indicate a safety problem associated with the administration of Dihydroergotamine Mesylate Injection, USP to subjects already receiving propranolol, there have been reports that propranolol may potentiate the vasoconstrictive action of ergotamine by blocking the vasodilating property of epinephrine. (etiqueta de Dihidroergotamina, Interacciones medicamentosas)

Digitalis, Clonidine, and Calcium Channel Blockers: Digitalis glycosides, clonidine, diltiazem and verapamil slow atrioventricular conduction and decrease heart rate. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Risk may be increased when used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (etiqueta de Doxercalciferol, Advertencias y precauciones)

Give a low dose of beta-blockers initially, and increase only after ECG verification of good tolerability [see Drug Interactions (7.3) , Clinical Pharmacology (12.3) ] . (etiqueta de Dronedarona, Interacciones medicamentosas)

Medications that may increase serum potassium concentration include ACE inhibitors, angiotensin-II receptor antagonists, potassium-sparing diuretics, potassium supplementation, heparin, aldosterone antagonists, and NSAIDS. (etiqueta de Drospirenona y etinilestradiol, Advertencias y precauciones)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Patients at risk of excessive hypotension include those with the following conditions or characteristics: heart failure with systolic blood pressure below 100 mmHg, ischemic heart disease, cerebrovascular disease, hyponatremia, high dose diuretic therapy, renal dialysis, or severe volume and/or salt depletion of any etiology. (etiqueta de Enalapril, Advertencias y precauciones)

Following initiation and titration of Epogen, approximately 25% of patients on dialysis required initiation of or increases in antihypertensive therapy; hypertensive encephalopathy and seizures have been reported in patients with CKD receiving Epogen. (etiqueta de Epoetina alfa, Advertencias y precauciones)

Additional reductions in blood pressure may occur when VELETRI is administered with diuretics, antihypertensive agents, or other vasodilators. (etiqueta de Epoprostenol, Interacciones medicamentosas)

The beta-blocker Inderal (propranolol) has been reported to potentiate the vasoconstrictive action of ergotamine tartrate and caffeine tablets by blocking the vasodilating property of epinephrine. (etiqueta de Ergotamina y cafeína, Interacciones medicamentosas)

Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (etiqueta de Escitalopram, Advertencias y precauciones)

Antihypertensive agents clonidine, guanfacine, or moxonidine: Beta blockers also increase the risk of clonidine-, guanfacine-, or moxonidine-withdrawal rebound hypertension. (etiqueta de Esmolol, Interacciones medicamentosas)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etiqueta de Esomeprazol, Advertencias y precauciones)

If such symptoms occur, increase diuretics and restore clinical stability before advancing the dose of metoprolol. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

If such symptoms occur, increase diuretics and restore clinical stability before advancing the dose of metoprolol. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Digitalis, Clonidine, and Calcium Channel Blockers: Digitalis glycosides, clonidine, diltiazem and verapamil slow atrioventricular conduction and decrease heart rate. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Catecholamine-depleting drugs (e.g., MAO inhibitors): Hypotension, bradycardia. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

…treatment with Class 1 and Class III antiarrhythmics, 4) treatment with monoamine oxidase inhibitors (MAOI's), 5) concomitant treatment with other drug products known to prolong the QT interval and 6) electrolyte imbalance, in particular hypokalemia and hypomagnesemia, or concomitant treatment with drugs (e.g., diuretics) that may cause electrolyte imbalance. (etiqueta de Fentanilo, Advertencias y precauciones)

Concomitant administration of hydrochlorothiazide alone with topiramate alone has been shown to increase the C max and AUC of topiramate by 27% and 29%, respectively. (etiqueta de Fentermina y topiramato, Interacciones medicamentosas)

Hydrochlorothiazide In a pharmacokinetic interaction study, coadministration of multiple-dose hydrochlorothiazide to healthy volunteers receiving fluconazole increased plasma concentrations of fluconazole by 40%. (etiqueta de Fluconazol, Interacciones medicamentosas)

Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (etiqueta de Fludrocortisona, Interacciones medicamentosas)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly . (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Propranolol or metoprolol : Reduce dose if coadministered and titrate more cautiously ( 7.3 ). (etiqueta de Fluvoxamina, Interacciones medicamentosas)

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly . (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

When diuretics are indicated, thiazides are recommended over loop diuretics because the latter inhibit renal tubular secretion, and may impair elimination of FOSCAVIR, potentially leading to toxicity. (etiqueta de Foscarnet, Interacciones medicamentosas)

In separate single or multiple dose pharmacokinetic interaction studies with chlorthalidone, nifedipine, propranolol, hydrochlorothiazide, cimetidine, metoclopramide, propantheline, digoxin, and warfarin, the bioavailability of fosinoprilat was not altered by coadministration of fosinopril with any one of these drugs. (etiqueta de Fosinopril, Interacciones medicamentosas)

The thiazide component of fosinopril sodium and hydrochlorothiazide may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (etiqueta de Fosinopril e hidroclorotiazida, Advertencias)

If such symptoms occur, increase diuretics and restore clinical stability before advancing the dose of metoprolol. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Table 4: Clinically Significant Drug Interaction with GVOKE and GVOKE VialDx Beta-Blockers Clincial Impact: Patients taking beta-blockers may have a transient increase in pulse and blood pressure when given GVOKE or GVOKE VialDx. (etiqueta de Glucagón, Interacciones medicamentosas)

Caution is advised when haloperidol decanoate is used in combination with drugs known to cause electrolyte imbalance (e.g., diuretics or corticosteroids) because hypokalemia, hypomagnesemia, and hypocalcemia are risk factors for QT prolongation. (etiqueta de Haloperidol, Interacciones medicamentosas)

Example: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Hidrocodona, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Diuretics : Hydrocodone may reduce the efficacy of diuretics. (etiqueta de Hidrocodona y clorfenamina, Interacciones medicamentosas)

Diuretics : Hydrocodone may reduce the efficacy of diuretics. (etiqueta de Hidrocodona y homatropina, Interacciones medicamentosas)

Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Hidrocodona y paracetamol, Interacciones medicamentosas)

Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Hidromorfona, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etiqueta de Iloperidona, Advertencias y precauciones)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with imipramine hydrochloride tablets. (etiqueta de Imipramina, Advertencias)

Drug Interactions Other Antihypertensives: Indapamide may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Indapamida, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly . (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly . (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Hypotension in Volume or Salt-Depleted Patients In patients with an activated renin-angiotensin system, such as volume or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initialization of treatment with AVAPRO. (etiqueta de Irbesartán, Advertencias y precauciones)

Concomitant Use with Beta Blockers Concomitant use of beta blockers may exaggerate the cardiovascular effects of inhalational anesthetics, including hypotension and negative inotropic effects. (etiqueta de Isoflurano, Interacciones medicamentosas)

Catecholamine-depleting drugs (e.g., MAO inhibitors): Hypotension, bradycardia. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly . (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Digitalis, Clonidine, and Calcium Channel Blockers: Digitalis glycosides, clonidine, diltiazem and verapamil slow atrioventricular conduction and decrease heart rate. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

The risk of bradycardia increases with concomitant administration of drugs that slow heart rate (e.g., digoxin, amiodarone, beta-blockers). (etiqueta de Ivabradina, Interacciones medicamentosas)

Antivirals indinavir, maraviroc, saquinavir Beta Blockers nadolol Calcium Channel Blockers felodipine, nisoldipine other dihydropyridines, verapamil Calcium channel blockers can have a negative inotropic effect which may be additive to those of ketoconazole. (etiqueta de Ketoconazol, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

VIMPAT should also be used with caution in patients on concomitant medications that affect cardiac conduction, including sodium channel blockers, beta-blockers, calcium channel blockers, potassium channel blockers, and medications that prolong the PR interval [see Drug Interactions (7.2) ] . (etiqueta de Lacosamida, Advertencias y precauciones)

Bradycardia-Inducing Drugs (e.g., beta-blockers) : Lanreotide Injection may decrease heart rate. (etiqueta de Lanreotida, Interacciones medicamentosas)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etiqueta de Lansoprazol, Advertencias y precauciones)

Patients also taking beta blockers, or those with underlying cardiac comorbidities and/or advanced liver disease, may be at increased risk for symptomatic bradycardia with coadministration of amiodarone. (etiqueta de Ledipasvir y sofosbuvir, Advertencias y precauciones)

Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk. (etiqueta de Levomilnaciprán, Advertencias y precauciones)

Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Levorfanol, Interacciones medicamentosas)

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly . (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Drug or Drug Class Effect Beta-adrenergic antagonists e.g., Propranolol > 160 mg/day) In patients treated with large doses of propranolol (> 160 mg/day), T 3 and T 4 levels change slightly, TSH levels remain normal, and patients are clinically euthyroid. (etiqueta de Levotiroxina, Interacciones medicamentosas)

Patients may be unresponsive to the usual doses of epinephrine used to treat allergic reaction. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Catecholamine-depleting drugs (e.g., MAO inhibitors): Hypotension, bradycardia. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Drug or Drug Class Effect Beta-adrenergic antagonists (e.g., Propranolol >160 mg/day) In patients treated with large doses of propranolol (>160 mg/day), T3 and T4 levels change, TSH levels remain normal, and patients are clinically euthyroid. (etiqueta de Liotironina, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Patients at risk of excessive hypotension include those with the following conditions or characteristics: heart failure with systolic blood pressure below 100 mmHg, ischemic heart disease, cerebrovascular disease, hyponatremia, high dose diuretic therapy, renal dialysis, or severe volume and/or salt depletion of any etiology. (etiqueta de Lisinopril, Advertencias y precauciones)

When a diuretic is added to the therapy of a patient receiving lisinopril, an additional antihypertensive effect is usually observed (see DOSAGE AND ADMINISTRATION ). (etiqueta de Lisinopril e hidroclorotiazida, Interacciones medicamentosas)

Lithium: Risk of lithium toxicity. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Hypotension in Volume- or Salt-Depleted Patients In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment with COZAAR. (etiqueta de Losartán, Advertencias y precauciones)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive drugs), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and patients… (etiqueta de Lumateperona, Advertencias y precauciones)

Patients at increased risk of these adverse reactions or at increased risk of developing complications from hypotension include those with dehydration, hypovolemia, treatment with antihypertensive medication, history of cardiovascular disease (e.g., heart failure, myocardial infarction, ischemia, or conduction abnormalities), history of cerebrovascular disease,… (etiqueta de Lurasidona, Advertencias y precauciones)

The action of Mecamylamine HCl may be potentiated by anesthesia, other antihypertensive drugs and alcohol. (etiqueta de Mecamilamina, Interacciones medicamentosas)

There is one report of cardiopulmonary arrest, with full recovery, in a patient who was taking a beta blocker (propranolol) (see PRECAUTIONS, Cardiac Effects ). (etiqueta de Mefloquina, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Closely monitor patients with risk factors for development of prolonged QT interval (e.g., cardiac hypertrophy, concomitant diuretic use, hypokalemia, hypomagnesemia), a history of cardiac conduction abnormalities, and those taking medications affecting cardiac conduction. (etiqueta de Metadona, Advertencias y precauciones)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Beta-blockers Caution should be exercised when methylergonovine maleate is used concurrently with beta-blockers. (etiqueta de Metilergometrina, Interacciones medicamentosas)

Antihypertensive Drugs: Monitor blood pressure. (etiqueta de Metilfenidato, Interacciones medicamentosas)

…(oral): Due to potential inhibition of vitamin K activity by methimazole, the activity of oral anticoagulants (e.g., warfarin) may be increased; additional monitoring of PT/INR should be considered, especially before surgical procedures. β-adrenergic blocking agents: Hyperthyroidism may cause an increased clearance of beta blockers with a high extraction ratio. (etiqueta de Metimazol, Interacciones medicamentosas)

If such symptoms occur, increase diuretics and restore clinical stability before advancing the dose of Metoprolol Tartrate Tablets [see Dosage and Administration (2) ]. (etiqueta de Metoprolol, Advertencias y precauciones)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Geriatric Use ( 8.5 )] . (etiqueta de Milnaciprán, Advertencias y precauciones)

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly . (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia [see Use in Specific Populations (8.5) ] . (etiqueta de Mirtazapina, Advertencias y precauciones)

However, a retrospective analysis of the use of antihypertensive medication in these studies showed that a greater proportion of patients on PROVIGIL required new or increased use of antihypertensive medications (2.4%) compared to patients on placebo (0.7%). (etiqueta de Modafinilo, Advertencias y precauciones)

Symptomatic hypotension is most likely to occur in patients who have been salt- and volume- depleted as a result of prolonged diuretic therapy, dietary salt restriction, dialysis, diarrhea, or vomiting. (etiqueta de Moexipril, Advertencias)

Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Morfina, Interacciones medicamentosas)

Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (etiqueta de Motixafortida, Advertencias y precauciones)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Although beta-blockers should be avoided in overt congestive heart failure, if necessary, they can be used with caution in patients with a history of failure who are well-compensated, usually with digitalis and diuretics. (etiqueta de Nadolol, Advertencias)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Nalbufina, Interacciones medicamentosas)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antihypertensive Therapy Niacin may potentiate the effects of ganglionic blocking agents and vasoactive drugs resulting in postural hypotension. (etiqueta de Niacina, Interacciones medicamentosas)

Digitalis, Clonidine, and Calcium Channel Blockers: Digitalis glycosides, clonidine, diltiazem and verapamil slow atrioventricular conduction and decrease heart rate. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Digitalis, Clonidine, and Calcium Channel Blockers: Digitalis glycosides, clonidine, diltiazem and verapamil slow atrioventricular conduction and decrease heart rate. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Digitalis, Clonidine, and Calcium Channel Blockers: Digitalis glycosides, clonidine, diltiazem and verapamil slow atrioventricular conduction and decrease heart rate. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Digitalis, Clonidine, and Calcium Channel Blockers: Digitalis glycosides, clonidine, diltiazem and verapamil slow atrioventricular conduction and decrease heart rate. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antihypertensives: Possible additive hypotensive effects. (etiqueta de Nitroglicerina, Interacciones medicamentosas)

Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (‎7.2) ]. (etiqueta de Octreotida, Advertencias y precauciones)

…of myocardial infarction or ischemia, heart failure, or conduction abnormalities), cerebrovascular disease, and conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications) where the occurrence of syncope, or hypotension and/or bradycardia might put the patient at increased medical risk. (etiqueta de Olanzapina, Advertencias y precauciones)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Oliceridina, Interacciones medicamentosas)

Hypotension in Volume- or Salt-Depleted Patients In patients with an activated renin-angiotensin-aldosterone system, such as volume- and/or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may be anticipated after initiation of treatment with Benicar. (etiqueta de Olmesartán, Advertencias y precauciones)

Digitalis, Clonidine, and Calcium Channel Blockers: Digitalis glycosides, clonidine, diltiazem and verapamil slow atrioventricular conduction and decrease heart rate. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (etiqueta de Omeprazol, Advertencias y precauciones)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (etiqueta de Omeprazol y bicarbonato de sodio, Advertencias y precauciones)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Oxicodona, Interacciones medicamentosas)

Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Oxicodona y paracetamol, Interacciones medicamentosas)

Caution in using drugs such as beta-blockers, anti-hypertensives, and/or cardiac glycosides is advised. (etiqueta de Oximetazolina, Interacciones medicamentosas)

Examples: butorphanol, nalbuphine, pentazocine, buprenorphine Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Oximorfona, Interacciones medicamentosas)

Use ERZOFRI with caution in patients with known cardiovascular disease (e.g., heart failure, history of myocardial infarction or ischemia, conduction abnormalities), cerebrovascular disease, or conditions that predispose the patient to hypotension (e.g., dehydration, hypovolemia, and treatment with antihypertensive medications). (etiqueta de Paliperidona, Advertencias y precauciones)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (etiqueta de Pantoprazol, Advertencias y precauciones)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Paracetamol y codeína, Interacciones medicamentosas)

The risk may be increased when Paricalcitol Injection is used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (etiqueta de Paricalcitol, Advertencias y precauciones)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Adjustments in the dose of drugs known to slow the heart rate (e.g., beta-blockers, calcium channel blockers) and correction of electrolyte disturbances may be necessary when initiating or during the course of SIGNIFOR LAR treatment. (etiqueta de Pasireotida, Advertencias y precauciones)

Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (etiqueta de Pazopanib, Advertencias y precauciones)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Pentazocina y naloxona, Interacciones medicamentosas)

Small decreases in blood pressure have been observed in some patients treated with pentoxifylline extended-release tablets; periodic systemic blood pressure monitoring is recommended for patients receiving concomitant antihypertensive therapy. (etiqueta de Pentoxifilina, Interacciones medicamentosas)

Symptomatic hypotension is most likely to occur in patients who have been volume or salt-depleted as a result of prolonged diuretic therapy, dietary salt restriction, dialysis, diarrhea or vomiting [see Dosage and Administration (2.1) ] . (etiqueta de Perindopril, Advertencias y precauciones)

Examples: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Petidina (meperidina), Interacciones medicamentosas)

Drug Interactions Pilocarpine should be administered with caution to patients taking beta-adrenergic antagonists because of the possibility of conduction disturbances. (etiqueta de Pilocarpina, Interacciones medicamentosas)

Although beta-blockers should be avoided in overt congestive heart failure, if necessary, pindolol tablets can be used with caution in patients with a history of failure who are well-compensated, usually with digitalis and diuretics. (etiqueta de Pindolol, Advertencias)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Use with caution in persons with increased risk of anticholinergic reactions, such as persons with bronchial asthma, chronic obstructive pulmonary disease, bradycardia, cardiac arrhythmias, beta blocker treatment (increased risk of anticholinergic reactions). (etiqueta de Piridostigmina, Advertencias y precauciones)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Experience with PONVORY is limited in patients receiving concurrent therapy with drugs that decrease heart rate (e.g., beta-blockers, non-dihydropyridine calcium channel blockers - diltiazem and verapamil, and other drugs that may decrease heart rate such as digoxin). (etiqueta de Ponesimod, Advertencias y precauciones)

Syncopal episodes have usually occurred within 30 to 90 minutes of the initial dose of the drug; occasionally, they have been reported in association with rapid dosage increases or the introduction of another antihypertensive drug into the regimen of a patient taking high doses of prazosin hydrochloride capsules. (etiqueta de Prazosina, Advertencias)

Patients may be unresponsive to the usual doses of epinephrine used to treat allergic reaction. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

Diuretics : Codeine may reduce the efficacy of diuretics. (etiqueta de Prometazina y codeína, Interacciones medicamentosas)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Beta-adrenergic blocking agents: Hyperthyroidism may cause an increased clearance of beta blockers with a high extraction ratio. (etiqueta de Propiltiouracilo, Interacciones medicamentosas)

Quetiapine should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (etiqueta de Quetiapina, Advertencias y precauciones)

The thiazide component of quinapril and hydrochlorothiazide tablets may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic- blocking drugs. (etiqueta de Quinapril e hidroclorotiazida, Advertencias)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Although clinical drug interaction studies have not been performed, antimalarial doses (greater than or equal to 600 mg) of quinine may inhibit the metabolism of other drugs that are CYP2D6 substrates (e.g., flecainide, debrisoquine, dextromethorphan, metoprolol, paroxetine ). (etiqueta de Quinina, Interacciones medicamentosas)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (etiqueta de Rabeprazol, Advertencias y precauciones)

Experience with another ACE inhibitor suggests that these increases would be reversible upon discontinuation of ramipril and/or diuretic therapy. (etiqueta de Ramipril, Advertencias y precauciones)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Catecholamine-depleting drugs (e.g., MAO inhibitors): Hypotension, bradycardia. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Decrease exposure Beta-blockers Metoprolol Decrease exposure Propranolol Decrease exposure Benzodiazepines Diazepam , Administered with rifampin 1200 mg daily Decrease exposure Benzodiazepine-related drugs Zopiclone Decrease AUC by 82% Zolpidem Decrease AUC by 73% Calcium Channel Blockers Diltiazem Decrease exposure Nifedipine Rifampin 1200 mg administered as… (etiqueta de Rifampicina, Interacciones medicamentosas)

…Anticonvulsants Phenytoin Antimalarials Quinine Azole Antifungals Fluconazole, itraconazole, ketoconazole Antipsychotics Haloperidol Barbiturates Phenobarbital Benzodiazepines Diazepam Beta-Blockers Propranolol Calcium Channel Blockers Diltiazem, nifedipine, verapamil Cardiac Glycoside Preparations Digoxin Corticosteroids Prednisone Fibrates Clofibrate Oral Hypoglycemics… (etiqueta de Rifapentina, Interacciones medicamentosas)

Consider the potential for symptomatic hypotension or ischemia in patients with hypovolemia, severe left ventricular outflow obstruction, resting hypotension, autonomic dysfunction, or concomitant treatment with antihypertensives or strong CYP and P-gp/BCRP inhibitors [see Drug Interactions (7.2) and Clinical Pharmacology (12.3) ] . (etiqueta de Riociguat, Advertencias y precauciones)

Clinically significant hypotension has been observed with concomitant use of oral RISPERDAL and antihypertensive medication. (etiqueta de Risperidona, Advertencias y precauciones)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Nadolol/Metoprolol : In a drug interactions study, effects of multiple doses of nadolol 80 mg or metoprolol 100 mg every 12 hours on the pharmacokinetics of a single dose of 10 mg rizatriptan were evaluated in healthy subjects (n=12). (etiqueta de Rizatriptán, Interacciones medicamentosas)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Patients on beta-blockers may not manifest changes in heart rate, but blood pressure monitoring can detect a rise in systolic blood pressure. (etiqueta de Ropivacaína, Advertencias y precauciones)

Patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients (e.g., those being treated with high doses of diuretics), are at greater risk. (etiqueta de Sacubitrilo y valsartán, Advertencias y precauciones)

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly . (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly . (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Catecholamine-depleting drugs (e.g., MAO inhibitors): Hypotension, bradycardia. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (etiqueta de Sertralina, Advertencias y precauciones)

Caution is advised when SILDENAFIL ORAL FILM is co-administered with alpha-blockers or antihypertensives. (etiqueta de Sildenafilo, Advertencias y precauciones)

However, patients in the Phase 3 clinical studies taking concomitant antihypertensive medications with silodosin capsules did not experience a significant increase in the incidence of syncope, dizziness, or orthostasis. (etiqueta de Silodosina, Advertencias y precauciones)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Patients also taking beta blockers, or those with underlying cardiac comorbidities and/or advanced liver disease may be at increased risk for symptomatic bradycardia with coadministration of amiodarone. (etiqueta de Sofosbuvir y velpatasvir, Advertencias y precauciones)

Consider temporary or permanent discontinuation for severe or persistent hypertension despite antihypertensive therapy. (etiqueta de Sorafenib, Advertencias y precauciones)

Special attention should be given to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or patients receiving concomitant diuretic drugs. (etiqueta de Sotalol, Advertencias y precauciones)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Initiate and/or adjust antihypertensive therapy as appropriate. (etiqueta de Sunitinib, Advertencias y precauciones)

Prolonged Neuromuscular Block in Patients with Hypokalemia or Hypocalcemia Neuromuscular blockade may be prolonged in patients with hypokalemia (e.g., after severe vomiting, diarrhea, digitalisation and diuretic therapy) or hypocalcemia (e.g., after massive transfusions). (etiqueta de Suxametonio (succinilcolina), Advertencias y precauciones)

• Hypertension: May require antihypertensive therapy; monitor relevant drug interactions. (etiqueta de Tacrolimus, Advertencias y precauciones)

…use of skeletal muscle relaxants and opioids, consider prescribing naloxone for the emergency treatment of opioid overdose [see Dosage and Administration (2.2) , Warnings and Precautions (5.2 , 5.3) ] Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Tapentadol, Interacciones medicamentosas)

Beta-adrenergic Receptor Antagonists (e.g., acebutolol, metoprolol) Beta-adrenergic receptor antagonists have been shown to reduce the production of melatonin via specific inhibition of beta-1 adrenergic receptors. (etiqueta de Tasimelteón, Interacciones medicamentosas)

Hypotension In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of therapy with telmisartan tablets. (etiqueta de Telmisartán, Advertencias y precauciones)

Digitalis, Clonidine, and Calcium Channel Blockers: Digitalis glycosides, clonidine, diltiazem and verapamil slow atrioventricular conduction and decrease heart rate. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly . (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Risk of Hypotension with Concomitant Use of Other Antihypertensive Agents and Phospodiesterase Type 5 Inhibitors (PDE5-I): Concomitant administration of TEZRULY with antihypertensives or phosphodiesterase-5 (PDE-5) inhibitors can result in additive blood pressure lowering effects and symptomatic hypotension (5.3). (etiqueta de Terazosina, Advertencias y precauciones)

CYP2D6 inhibitors: Increased metoprolol concentration. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly . (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

In patients with hypertension on antihypertensive therapy, TLANDO increased the mean systolic/diastolic BP by 4.8/1.6 mm Hg from baseline. [see Adverse Reactions ( 6.1 )] . (etiqueta de Testosterona, Advertencias y precauciones)

Drug Interactions with Metoprolol Catecholamine Depleting Drugs: The concomitant use of catecholamine-depleting drugs (e.g., reserpine, monoamine oxidase (MAO) inhibitors) with beta adrenergic blockers may have an additive affect and increase the risk of hypotension or bradycardia CYP2D6 Inhibitors: Drugs that are strong inhibitors of CYP2D6 such as quinidine,… (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly . (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Antidiabetic drugs: Dosage adjustment may be required. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Some diuretics can enhance aminoglycoside toxicity by altering antibiotic concentrations in serum and tissue. (etiqueta de Tobramicina, Interacciones medicamentosas)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects of diuretics. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Co-administration of diuretics also increases the risk of too rapid correction of serum sodium and such patients should undergo close monitoring of serum sodium. (etiqueta de Tolvaptán, Advertencias y precauciones)

Hydrochlorothiazide (HCTZ) Topiramate C max and AUC increased when HCTZ was added to immediate-release topiramate. (etiqueta de Topiramato, Interacciones medicamentosas)

If such symptoms occur, increase diuretics and restore clinical stability before advancing the dose of metoprolol. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Drugs that decrease renal calcium excretion, e.g., thiazide diuretics, may increase the risk of hypercalcemia in patients receiving FARESTON. (etiqueta de Toremifeno, Interacciones medicamentosas)

Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Tramadol, Interacciones medicamentosas)

Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Tramadol y paracetamol, Interacciones medicamentosas)

Symptomatic hypotension is most likely to occur in patients who have been salt- or volume-depleted as a result of prolonged treatment with diuretics, dietary salt restriction, dialysis, diarrhea, or vomiting. (etiqueta de Trandolapril, Advertencias)

Concomitant use with an antihypertensive may require a reduction in the dose of the antihypertensive drug. (etiqueta de Trazodona, Advertencias y precauciones)

If such symptoms occur, increase diuretics and restore clinical stability before advancing the dose of metoprolol. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

If such symptoms occur, increase diuretics and restore clinical stability before advancing the dose of metoprolol. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Trifluoperazina, Precauciones)

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly . (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly . (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Drug Interactions with Metoprolol Catecholamine Depleting Drugs: The concomitant use of catecholamine-depleting drugs (e.g., reserpine, monoamine oxidase (MAO) inhibitors) with beta adrenergic blockers may have an additive affect and increase the risk of hypotension or bradycardia CYP2D6 Inhibitors: Drugs that are strong inhibitors of CYP2D6 such as quinidine,… (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

In patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients receiving high doses of diuretics, symptomatic hypotension may occur. (etiqueta de Valsartán, Advertencias y precauciones)

Vardenafil hydrochloride tablets can potentiate the hypotensive effects of nitrates, alpha- blockers, and antihypertensives. (etiqueta de Vardenafilo, Interacciones medicamentosas)

Caution should be exercised with co-administration of venlafaxine and metoprolol. (etiqueta de Venlafaxina, Interacciones medicamentosas)

Digitalis, Clonidine, and Calcium Channel Blockers: Digitalis glycosides, clonidine, diltiazem and verapamil slow atrioventricular conduction and decrease heart rate. (etiqueta de Metoprolol e hidroclorotiazida, Interacciones medicamentosas)

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly . (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs and SNRIs [see Use in Specific Populations ( 8.5 )] . (etiqueta de Vilazodona, Advertencias y precauciones)

Los diuréticos tiazídicos reducen la excreción de calcio; combinados con suplementos de vitamina D y de calcio, esto puede llevar a hipercalcemia, sobre todo en adultos mayores. (NIH Office of Dietary Supplements, Vitamin D)

Also, patients taking diuretics or who are otherwise volume-depleted can be at greater risk. (etiqueta de Vortioxetina, Advertencias y precauciones)

Concurrent use with potassium-containing medications, potassium-sparing diuretics and angiotensin-converting enzyme inhibitors (ACE inhibitors) may result in hyperkalemia and cardiac arrhythmias or cardiac arrest. (etiqueta de Yoduro de potasio, Interacciones medicamentosas)

Zileuton increases propranolol levels and beta-blocker activity. (etiqueta de Zileutón, Interacciones medicamentosas)

Hypokalemia may result from diuretic therapy, diarrhea, and other causes. (etiqueta de Ziprasidona, Advertencias y precauciones)

Effects of Adenosine on Other Drugs Adenosine injection has been given with other cardioactive drugs (such as beta adrenergic blocking agents, cardiac glycosides, and calcium channel blockers) without apparent adverse interactions, but its effectiveness with these agents has not been systematically evaluated. (etiqueta de Adenosina, Interacciones medicamentosas)

Coadministration of 1 Dyazide (triamterene/hydrochlorothiazide) resulted in a higher plasma amantadine hydrochloride concentration in a 61-year old man receiving amantadine hydrochloride 100 mg TID for Parkinson's disease. (etiqueta de Amantadina, Interacciones medicamentosas)

Patients required intervention with a diuretic, fluid management, or, in some cases, hospitalization for decompensating heart failure. (etiqueta de Ambrisentán, Advertencias y precauciones)

Because of its relative beta 1 cardio-selectivity, however, metoprolol tartrate may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Patients required intervention with a diuretic, fluid management, or hospitalization for decompensating heart failure. (etiqueta de Bosentán, Advertencias y precauciones)

In such cases, butorphanol should be discontinued and the hypertension treated with antihypertensive drugs. (etiqueta de Butorfanol, Advertencias)

Los diuréticos tiazídicos reducen la excreción de calcio, por lo que una ingesta alta de calcio puede elevar el calcio en sangre. (NIH Office of Dietary Supplements, Calcium)

Because of its relative beta 1 cardio-selectivity, however, metoprolol tartrate may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Acthar Gel may accentuate the electrolyte loss associated with diuretic therapy. (etiqueta de Corticotropina, Interacciones medicamentosas)

Fluid retention events were typically managed by supportive care measures that may include diuretics or short courses of steroids. (etiqueta de Dasatinib, Advertencias y precauciones)

If other contraceptive methods are not suitable, hormonal contraceptive therapy may continue combined with antihypertensive therapy. (etiqueta de Desogestrel y etinilestradiol, Advertencias)

Examples of alkalinizing agents include gastrointestinal alkalinizing agents (e.g., sodium bicarbonate) and urinary alkalinizing agents (e.g. acetazolamide, some thiazides). (etiqueta de Dexanfetamina, Interacciones medicamentosas)

Because of its relative beta 1 cardio-selectivity, however, metoprolol tartrate may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (etiqueta de Docetaxel, Advertencias y precauciones)

Pheochromocytoma: First initiate therapy with an alpha blocker. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Pheochromocytoma: First initiate therapy with an alpha blocker. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Examples: α-adrenergic antagonists, β-adrenergic receptor antagonists, reserpine, quinidine, mephentermine Other Drug Interactions G u anethidine C linical Impact: Ephedrine may inhibit the neuron blockage produced by guanethidine, resulting in loss of antihypertensive effectiveness. (etiqueta de Efedrina, Interacciones medicamentosas)

Because of its relative beta 1 cardio-selectivity, however, metoprolol tartrate may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

In addition to discontinuation of the drug, diuretic therapy may be required. (etiqueta de Estrógenos esterificados y metiltestosterona, Advertencias)

In Vivo Drug Interaction Studies Based on drug interaction studies in healthy patients, ULORIC does not have clinically significant interactions with colchicine, naproxen, indomethacin, hydrochlorothiazide, warfarin or desipramine [see Clinical Pharmacology (12.3) ]. (etiqueta de Febuxostat, Interacciones medicamentosas)

Pheochromocytoma: First initiate therapy with an alpha blocker. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Pheochromocytoma: First initiate therapy with an alpha blocker. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

…PROSCAR was concomitantly used in clinical studies with acetaminophen, acetylsalicylic acid, α-blockers, angiotensin-converting enzyme (ACE) inhibitors, analgesics, anti-convulsants, beta-adrenergic blocking agents, diuretics, calcium channel blockers, cardiac nitrates, HMG-CoA reductase inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), benzodiazepines,… (etiqueta de Finasterida, Interacciones medicamentosas)

Drugs That Slow Heart Rate or Atrioventricular Conduction (e.g., beta blockers or diltiazem) Experience with GILENYA in patients receiving concurrent therapy with drugs that slow the heart rate or AV conduction (e.g., beta blockers, digoxin, or heart rate-slowing calcium channel blockers, such as diltiazem or verapamil) is limited. (etiqueta de Fingolimod, Interacciones medicamentosas)

Drugs that may cause hypercalcemia: Vitamin D, vitamin A, thiazide diuretics, estrogen, calcipotriene and teriparatide administration may cause hypercalcemia. (etiqueta de Gluconato de calcio, Interacciones medicamentosas)

Because of its relative beta 1 cardio-selectivity, however, metoprolol tartrate may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Because of its relative beta 1 cardio-selectivity, however, metoprolol tartrate may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Because of its relative beta 1 cardio-selectivity, however, metoprolol tartrate may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

ACE Inhibitors FIRAZYR is a bradykinin B2 receptor antagonist and thereby has the potential to have a pharmacodynamic interaction with ACE inhibitors where FIRAZYR may attenuate the antihypertensive effect of ACE inhibitors. (etiqueta de Icatibant, Interacciones medicamentosas)

Because of its relative beta 1 cardio-selectivity, however, metoprolol tartrate may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Pheochromocytoma: First initiate therapy with an alpha blocker. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Abrupt withdrawal in thyrotoxicosis might precipitate a thyroid storm. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Because of its relative beta 1 cardio-selectivity, however, metoprolol tartrate may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Because of its relative beta 1 cardio-selectivity, however, metoprolol tartrate may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Postmarketing cases of edema and fluid retention occurring within weeks of starting OPSUMIT, some requiring intervention with a diuretic or hospitalization for decompensated heart failure, have been reported [see Adverse Reactions (6.2) ] . (etiqueta de Macitentán, Advertencias y precauciones)

El uso a largo plazo de diuréticos de asa y diuréticos tiazídicos aumenta la pérdida de magnesio por la orina. (NIH Office of Dietary Supplements, Magnesium)

Because of its relative beta 1 cardio-selectivity, however, metoprolol tartrate may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etiqueta de Metilprednisolona, Interacciones medicamentosas)

In addition to discontinuation of the drug, diuretic therapy may be required. (etiqueta de Metiltestosterona, Advertencias)

In a large compassionate use program mexiletine has been used concurrently with commonly employed antianginal, antihypertensive, and anticoagulant drugs without observed interactions. (etiqueta de Mexiletina, Interacciones medicamentosas)

…been observed in limited experience with patients in whom milrinone was used concurrently with the following drugs: digitalis glycosides; lidocaine, quinidine; hydralazine, prazosin; isosorbide dinitrate, nitroglycerin; chlorthalidone, furosemide, hydrochlorothiazide, spironolactone; captopril; heparin, warfarin, diazepam, insulin; and potassium supplements. (etiqueta de Milrinona, Interacciones medicamentosas)

Because of its relative beta 1 cardio-selectivity, however, metoprolol tartrate may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

The antihypertensive action of guanethidine and similar agents may be blocked. (etiqueta de Nortriptilina, Advertencias)

Because of its relative beta 1 cardio-selectivity, however, metoprolol tartrate may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Drug Interactions Metabolism of a number of medications, including antipsychotics, antidepressants, β-blockers, and antiarrhythmics, occurs through the cytochrome P450 2D6 isoenzyme (debrisoquine hydroxylase). (etiqueta de Perfenazina, Interacciones medicamentosas)

Los diuréticos de asa y los diuréticos tiazídicos aumentan la pérdida de potasio; a veces se prescribe un suplemento junto con ellos. (NIH Office of Dietary Supplements, Potassium)

Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etiqueta de Prednisolona, Interacciones medicamentosas)

Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etiqueta de Prednisona, Interacciones medicamentosas)

Because of its relative beta 1 cardio-selectivity, however, metoprolol tartrate may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Protriptyline may block the antihypertensive effect of guanethidine or similarly acting compounds. (etiqueta de Protriptilina, Advertencias)

Pheochromocytoma: First initiate therapy with an alpha blocker. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Because of its relative beta 1 cardio-selectivity, however, metoprolol tartrate may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Abrupt withdrawal in thyrotoxicosis might precipitate a thyroid storm. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Because of its relative beta 1 cardio-selectivity, however, metoprolol tartrate may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Amphotericin B injection and potassium-depleting agents: When corticosteroids are administered concomitantly with potassium-depleting agents ( i.e., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etiqueta de Triamcinolona, Interacciones medicamentosas)

Because of its relative beta 1 cardio-selectivity, however, metoprolol tartrate may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

Los diuréticos tiazídicos aumentan la pérdida de zinc por la orina con el uso a largo plazo. (NIH Office of Dietary Supplements, Zinc)

Beta-adrenergic blocking agents: Coadministration of beta-adrenergic blocking agents did not have any effect on either the safety or efficacy of ibutilide in the clinical trials. (etiqueta de Ibutilida, Interacciones medicamentosas)

Loop Diuretics Concomitant administration of a loop diuretic had no effect on the calcium-lowering action of pamidronate disodium. (etiqueta de Pamidronato, Interacciones medicamentosas)

Commonly Administered Drugs: Population analysis showed that commonly administered drugs (e.g., selegiline, amantadine, tricyclic antidepressants, benzodiazepines, ibuprofen, thiazides, antihistamines, anticholinergics) did not affect the clearance of ropinirole. (etiqueta de Ropinirol, Interacciones medicamentosas)

Table 5: Sevelamer Drug Interactions Oral drugs for which sevelamer did not alter the pharmacokinetics when administered concomitantly Digoxin Enalapril Iron Metoprolol Warfarin Oral drugs that have demonstrated interaction with sevelamer and are to be dosed separately from sevelamer carbonate Dosing Recommendations Ciprofloxacin Take at least 2 hours before… (etiqueta de Sevelámero, Interacciones medicamentosas)