Interaction Checker

Interaksi Dutasterid

Dutasterid (Avodart), golongan penghambat 5-alfa reduktase, memiliki 67 interaksi terdokumentasi dalam label FDA dan lembar fakta yang kami indeks: 2 mayor, 20 moderat, 35 minor, dan 10 dengan label yang melaporkan tidak ada interaksi bermakna. Setiap entri di bawah ini mengutip kalimat yang mendasarinya. Halaman obat ini adalah titik awal, bukan putusan untuk situasi Anda.

Interaksi dari label

Interaksi mayor (2)

  • Dutasterid dan tamsulosinpenghambat 5-alfa reduktaseMayor

    Patients with previously demonstrated, clinically significant hypersensitivity (e.g., serious skin reactions, angioedema) to dutasteride or other 5 alpha-reductase inhibitors [see Adverse Reactions (6.2) ]. (label Dutasterid, Kontraindikasi)

  • Finasteridpenghambat 5-alfa reduktaseMayor

    Patients with previously demonstrated, clinically significant hypersensitivity (e.g., serious skin reactions, angioedema) to dutasteride or other 5 alpha-reductase inhibitors [see Adverse Reactions (6.2) ]. (label Dutasterid, Kontraindikasi)

Interaksi moderat (20)

  • Amlodipinpenghambat kanal kalsium dihidropiridinModerat

    Calcium Channel Antagonists Coadministration of verapamil or diltiazem decreases dutasteride clearance and leads to increased exposure to dutasteride. (label Dutasterid, Interaksi obat)

  • Amlodipin dan atorvastatinpenghambat kanal kalsium dihidropiridinModerat

    Calcium Channel Antagonists Coadministration of verapamil or diltiazem decreases dutasteride clearance and leads to increased exposure to dutasteride. (label Dutasterid, Interaksi obat)

  • Amlodipin dan benazeprilpenghambat kanal kalsium dihidropiridinModerat

    Calcium Channel Antagonists Coadministration of verapamil or diltiazem decreases dutasteride clearance and leads to increased exposure to dutasteride. (label Dutasterid, Interaksi obat)

  • Amlodipin dan olmesartanpenghambat kanal kalsium dihidropiridinModerat

    Calcium Channel Antagonists Coadministration of verapamil or diltiazem decreases dutasteride clearance and leads to increased exposure to dutasteride. (label Dutasterid, Interaksi obat)

  • Amlodipin dan valsartanpenghambat kanal kalsium dihidropiridinModerat

    Calcium Channel Antagonists Coadministration of verapamil or diltiazem decreases dutasteride clearance and leads to increased exposure to dutasteride. (label Dutasterid, Interaksi obat)

  • Digoksinglikosida digitalisModerat

    Digoxin Dutasteride capsules do not alter the steady-state pharmacokinetics of digoxin when administered concomitantly at a dose of 0.5 mg/day for 3 weeks [see Clinical Pharmacology (12.3) ]. (label Dutasterid, Interaksi obat)

  • Diltiazempenghambat kanal kalsiumModerat

    Calcium Channel Antagonists Coadministration of verapamil or diltiazem decreases dutasteride clearance and leads to increased exposure to dutasteride. (label Dutasterid, Interaksi obat)

  • Felodipinpenghambat kanal kalsium dihidropiridinModerat

    Calcium Channel Antagonists Coadministration of verapamil or diltiazem decreases dutasteride clearance and leads to increased exposure to dutasteride. (label Dutasterid, Interaksi obat)

  • Isradipinpenghambat kanal kalsium dihidropiridinModerat

    Calcium Channel Antagonists Coadministration of verapamil or diltiazem decreases dutasteride clearance and leads to increased exposure to dutasteride. (label Dutasterid, Interaksi obat)

  • Itrakonazolantijamur azolModerat

    Dutasteride Oxybutynin Sildenafil (for erectile dysfunction) Tadalafil (for erectile dysfunction and benign prostatic hyperplasia) Tolterodine Monitor for adverse reactions. (label Itrakonazol, Interaksi obat)

  • Lopinavir dan ritonavirantiretroviralModerat

    Use with caution in patients taking potent, chronic cytochrome P450 (CYP)3A4 enzyme inhibitors (e.g., ritonavir). (label Dutasterid, Interaksi obat)

  • Nifedipinpenghambat kanal kalsium dihidropiridinModerat

    Calcium Channel Antagonists Coadministration of verapamil or diltiazem decreases dutasteride clearance and leads to increased exposure to dutasteride. (label Dutasterid, Interaksi obat)

  • Nikardipinpenghambat kanal kalsium dihidropiridinModerat

    Calcium Channel Antagonists Coadministration of verapamil or diltiazem decreases dutasteride clearance and leads to increased exposure to dutasteride. (label Dutasterid, Interaksi obat)

  • Nimodipinpenghambat kanal kalsium dihidropiridinModerat

    Calcium Channel Antagonists Coadministration of verapamil or diltiazem decreases dutasteride clearance and leads to increased exposure to dutasteride. (label Dutasterid, Interaksi obat)

  • Nirmatrelvir dan ritonavirantivirusModerat

    Use with caution in patients taking potent, chronic cytochrome P450 (CYP)3A4 enzyme inhibitors (e.g., ritonavir). (label Dutasterid, Interaksi obat)

  • Nisoldipinpenghambat kanal kalsium dihidropiridinModerat

    Calcium Channel Antagonists Coadministration of verapamil or diltiazem decreases dutasteride clearance and leads to increased exposure to dutasteride. (label Dutasterid, Interaksi obat)

  • Olmesartan, amlodipin, dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Moderat

    Calcium Channel Antagonists Coadministration of verapamil or diltiazem decreases dutasteride clearance and leads to increased exposure to dutasteride. (label Dutasterid, Interaksi obat)

  • RitonavirantiretroviralModerat

    Use with caution in patients taking potent, chronic cytochrome P450 (CYP)3A4 enzyme inhibitors (e.g., ritonavir). (label Dutasterid, Interaksi obat)

  • Telmisartan dan amlodipinpenghambat reseptor angiotensin II (ARB)Moderat

    Calcium Channel Antagonists Coadministration of verapamil or diltiazem decreases dutasteride clearance and leads to increased exposure to dutasteride. (label Dutasterid, Interaksi obat)

  • Verapamilpenghambat kanal kalsiumModerat

    Calcium Channel Antagonists Coadministration of verapamil or diltiazem decreases dutasteride clearance and leads to increased exposure to dutasteride. (label Dutasterid, Interaksi obat)

Penyebutan minor (35)

  • AmiodaronantiaritmiaMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Aprepitantpenghambat CYP3A4Minor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • AtazanavirantiretroviralMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • DarunavirantiretroviralMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Darunavir dan kobisistatantiretroviralMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • DronedaronantiaritmiaMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • EfavirenzantiretroviralMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Efavirenz, lamivudin, dan tenofovirantiretroviralMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Elvitegravir, kobisistat, emtrisitabin, dan tenofovirantiretroviralMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Eritromisinantibiotik makrolidaMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • EverolimusimunosupresanMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Flukonazolantijamur azolMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • FosamprenavirantiretroviralMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Fosaprepitantpenghambat CYP3A4Minor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Imatinibpenghambat CYP3A4Minor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • IsoniazidantibiotikMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Ivakaftorpenghambat CYP3A4Minor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Ketokonazolantijamur azolMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Klaritromisinantibiotik makrolidaMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • LenakapavirantiretroviralMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Mifepristonpenghambat CYP3A4Minor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Mirabegronagonis beta-adrenergikMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • NefazodonantidepresanMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Palbosiklibpenghambat CYP3A4Minor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • PerampanelantikonvulsanMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Posakonazolantijamur azolMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Ranolazinobat yang memperpanjang interval QTMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • SenobamatantikonvulsanMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • SiklosporinimunosupresanMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Simetidinpenghambat H2Minor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Suvoreksantsedatif-hipnotikMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Tamsulosinpenyekat alfaMinor

    Coadministration of dutasteride and tamsulosin resulted in similar changes to serum PSA as dutasteride monotherapy. (label Dutasterid, Peringatan dan perhatian)

  • Terazosinpenyekat alfaMinor

    The effect of administration of tamsulosin or terazosin on dutasteride pharmacokinetic parameters has not been evaluated. (label Dutasterid, Interaksi obat)

  • TikagrelorantiplateletMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

  • Vorikonazolantijamur azolMinor

    The effect of potent CYP3A4 inhibitors on dutasteride has not been studied. (label Dutasterid, Interaksi obat)

Tidak ada interaksi bermakna yang dilaporkan (10)

  • Alfuzosinpenyekat alfaTanpa interaksi

    Alpha-adrenergic Antagonists The administration of dutasteride capsules in combination with tamsulosin or terazosin has no effect on the steady-state pharmacokinetics of either alpha-adrenergic antagonist. (label Dutasterid, Interaksi obat)

  • Doksazosinpenyekat alfaTanpa interaksi

    Alpha-adrenergic Antagonists The administration of dutasteride capsules in combination with tamsulosin or terazosin has no effect on the steady-state pharmacokinetics of either alpha-adrenergic antagonist. (label Dutasterid, Interaksi obat)

  • Fenoksibenzaminpenyekat alfaTanpa interaksi

    Alpha-adrenergic Antagonists The administration of dutasteride capsules in combination with tamsulosin or terazosin has no effect on the steady-state pharmacokinetics of either alpha-adrenergic antagonist. (label Dutasterid, Interaksi obat)

  • Fentolaminpenyekat alfaTanpa interaksi

    Alpha-adrenergic Antagonists The administration of dutasteride capsules in combination with tamsulosin or terazosin has no effect on the steady-state pharmacokinetics of either alpha-adrenergic antagonist. (label Dutasterid, Interaksi obat)

  • Karvedilolpenyekat betaTanpa interaksi

    Alpha-adrenergic Antagonists The administration of dutasteride capsules in combination with tamsulosin or terazosin has no effect on the steady-state pharmacokinetics of either alpha-adrenergic antagonist. (label Dutasterid, Interaksi obat)

  • Kolestiraminsekuestran asam empeduTanpa interaksi

    Cholestyramine Administration of a single 5-mg dose of dutasteride capsules followed 1 hour later by 12 g of cholestyramine does not affect the relative bioavailability of dutasteride [see Clinical Pharmacology (12.3) ]. (label Dutasterid, Interaksi obat)

  • Labetalolpenyekat betaTanpa interaksi

    Alpha-adrenergic Antagonists The administration of dutasteride capsules in combination with tamsulosin or terazosin has no effect on the steady-state pharmacokinetics of either alpha-adrenergic antagonist. (label Dutasterid, Interaksi obat)

  • Prazosinpenyekat alfaTanpa interaksi

    Alpha-adrenergic Antagonists The administration of dutasteride capsules in combination with tamsulosin or terazosin has no effect on the steady-state pharmacokinetics of either alpha-adrenergic antagonist. (label Dutasterid, Interaksi obat)

  • Silodosinpenyekat alfaTanpa interaksi

    Alpha-adrenergic Antagonists The administration of dutasteride capsules in combination with tamsulosin or terazosin has no effect on the steady-state pharmacokinetics of either alpha-adrenergic antagonist. (label Dutasterid, Interaksi obat)

  • WarfarinantikoagulanTanpa interaksi

    Warfarin Concomitant administration of dutasteride capsules 0.5 mg/day for 3 weeks with warfarin does not alter the steady-state pharmacokinetics of the S- or R-warfarin isomers or alter the effect of warfarin on prothrombin time [see Clinical Pharmacology (12.3) ]. (label Dutasterid, Interaksi obat)

Periksa Dutasterid terhadap semua yang Anda gunakan. Tambahkan seluruh daftar Anda; setiap pasangan diperiksa sekaligus.

Buka di pemeriksa

Bukan nasihat medis. Tingkat keparahan mencerminkan kata-kata dalam label, bukan keadaan Anda. Tanda “mayor” bisa merupakan hal yang rutin di bawah pengawasan, dan tanda “minor” bisa menjadi penting pada dosis tinggi. Tanyakan kepada apoteker.